Best TWAS P=9.14e-09 · Best GWAS P=1.15e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RABGAP1L | 0.10 | 0.09 | blup | 647 | 0.11 | 4.0e-13 | 5.2 | 5.4 | 7.5e-08 | 0.89 | 0.17 | 0.83 | FALSE |
| 2 | GTEx | Brain Putamen basal ganglia | DARS2 | 0.13 | 0.01 | enet | 14 | 0.00 | 3.7e-01 | 5.9 | -5.4 | 7.7e-08 | -0.96 | 0.02 | 0.87 | FALSE |
| 3 | GTEx | Muscle Skeletal | MRPS14 | 0.03 | 0.01 | enet | 10 | 0.01 | 9.0e-02 | -3.9 | 5.2 | 2.5e-07 | 0.79 | 0.11 | 0.37 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | RABGAP1L | 0.23 | 0.03 | enet | 25 | 0.10 | 4.8e-09 | 4.9 | 5.2 | 2.1e-07 | 0.71 | 0.47 | 0.53 | FALSE |
| 5 | The Cancer Genome Atlas | Esophageal Carcinoma | GPR52 | 0.16 | 0.10 | lasso | 4 | 0.08 | 1.4e-03 | 5.3 | 5.3 | 1.0e-07 | 0.86 | 0.04 | 0.57 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | MRPS14 | 0.06 | 0.01 | blup | 38 | 0.02 | 9.1e-04 | 4.3 | 5.2 | 2.0e-07 | 0.82 | 0.00 | 0.58 | FALSE |
| 7 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | RABGAP1L | 0.12 | 0.03 | blup | 305 | 0.03 | 1.2e-02 | 5.9 | 5.8 | 9.1e-09 | 0.97 | 0.03 | 0.91 | TRUE |
| 8 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RABGAP1L | 0.12 | 0.01 | lasso | 6 | 0.03 | 5.0e-04 | 5.9 | 5.5 | 4.3e-08 | 0.88 | 0.03 | 0.97 | FALSE |