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chr1:242,590,540-244,359,621

Best TWAS P=4.46e-08 · Best GWAS P=3.06e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SDCCAG8 0.18 0.10 enet 25 0.11 1.4e-09 -4.9 -5.2 1.9e-07 0.86 0.08 0.91 FALSE
2 GTEx Artery Tibial SDCCAG8 0.14 0.02 lasso 3 0.03 1.9e-03 -5.3 -5.2 1.7e-07 0.93 0.02 0.97 FALSE
3 GTEx Cells Transformed fibroblasts SDCCAG8 0.23 0.25 enet 13 0.28 3.5e-21 -4.9 -5.3 1.1e-07 0.95 0.03 0.97 FALSE
4 GTEx Esophagus Mucosa SDCCAG8 0.17 0.15 lasso 4 0.15 3.3e-10 -5.4 -5.5 4.5e-08 0.97 0.02 0.98 TRUE
5 GTEx Esophagus Muscularis CEP170 0.09 0.11 lasso 4 0.10 1.2e-06 -5.3 -5.3 1.0e-07 0.97 0.02 0.98 FALSE
6 GTEx Heart Atrial Appendage SDCCAG8 0.14 0.06 lasso 7 0.06 1.6e-03 -5.3 -5.2 1.8e-07 0.95 0.02 0.95 FALSE
7 GTEx Nerve Tibial CEP170 0.09 0.08 lasso 1 0.05 1.1e-04 -5.4 -5.4 7.5e-08 0.97 0.02 0.98 FALSE
8 GTEx Whole Blood SDCCAG8 0.18 0.15 lasso 7 0.14 6.2e-13 -4.7 -5.2 2.5e-07 0.91 0.09 0.91 FALSE
9 METSIM Adipose SDCCAG8 0.12 0.13 enet 17 0.14 5.6e-21 -5.2 -5.3 1.0e-07 0.92 0.06 0.94 FALSE
10 The Cancer Genome Atlas Rectum Adenocarcinoma SDCCAG8 0.30 0.06 blup 113 0.12 8.0e-04 -5.5 -5.4 5.9e-08 0.86 0.01 0.90 FALSE