Best TWAS P=4e-08 · Best GWAS P=1.98e-07 conditioned to 0.884
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C2orf16 | 0.03 | 0.00 | lasso | 5 | 0.02 | 3.3e-03 | 4.7 | -5.3 | 1.1e-07 | -0.81 | 0.06 | 0.53 | FALSE |
| 2 | GTEx | Lung | ATRAID | 0.08 | 0.09 | lasso | 2 | 0.09 | 3.8e-07 | 5.0 | 5.3 | 1.1e-07 | 0.98 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Nerve Tibial | ATRAID | 0.12 | 0.05 | lasso | 4 | 0.04 | 1.0e-03 | 5.2 | 5.1 | 3.1e-07 | 1.00 | 0.01 | 0.98 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | ATRAID | 0.14 | 0.07 | enet | 15 | 0.09 | 1.3e-07 | 5.0 | 5.4 | 6.0e-08 | 0.92 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Whole Blood | NRBP1 | 0.06 | 0.00 | enet | 11 | 0.00 | 2.3e-01 | 5.0 | -5.4 | 5.2e-08 | -0.64 | 0.03 | 0.46 | TRUE |
| 6 | NTR | Blood | CGREF1 | 0.01 | 0.00 | blup | 307 | 0.01 | 5.7e-03 | 3.5 | 5.5 | 4.0e-08 | 0.81 | 0.02 | 0.88 | TRUE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SLC5A6 | 0.03 | 0.02 | blup | 49 | 0.02 | 4.6e-03 | 5.0 | -5.3 | 1.5e-07 | -0.91 | 0.01 | 0.83 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC5A6 | 0.07 | 0.05 | lasso | 3 | 0.03 | 5.6e-03 | 5.2 | -5.2 | 1.9e-07 | -1.00 | 0.01 | 0.95 | FALSE |