TWAS hub - CGREF1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1610	0.0560	2.1e-04	-0.002	0.015	-0.002	0.016	-0.001	8.8e-01	5.6e-03	6.6e-01	4.1e-03	4.9e-01
2	GTEx	Cells Transformed fibroblasts	0.0990	0.0350	9.3e-08	0.106	NA	0.111	NA	0.115	2.4e-08	NA	1.2e-08	NA	6.4e-09
3	GTEx	Esophagus Mucosa	0.0910	0.0430	1.7e-04	0.069	NA	0.043	NA	0.060	2.4e-05	NA	7.5e-04	NA	7.9e-05
4	GTEx	Muscle Skeletal	0.1099	0.0514	5.7e-06	0.035	NA	0.054	NA	0.061	2.0e-04	NA	5.1e-06	NA	1.2e-06
5	GTEx	Skin Sun Exposed Lower leg	0.0680	0.0380	1.6e-03	0.005	NA	0.002	NA	0.008	1.2e-01	NA	2.0e-01	NA	7.1e-02
6	NTR	Blood	0.0120	0.0068	9.8e-03	0.003	0.005	0.003	0.005	0.005	3.5e-02	5.7e-03	3.9e-02	5.8e-03	6.0e-03
7	ROSMAP	Brain Pre-frontal Cortex	0.0603	0.0221	2.1e-07	0.043	0.061	0.021	0.055	0.038	2.5e-06	2.6e-08	7.9e-04	1.2e-07	1.1e-05
8	TCGA	Breast Invasive Carcinoma	0.0147	0.0099	1.4e-03	0.003	0.008	0.008	NA	0.003	7.4e-02	7.9e-03	8.1e-03	NA	6.7e-02
9	TCGA	Cervical Squamous Cell Carcinoma	0.1090	0.0640	6.4e-03	0.026	0.023	0.002	NA	0.012	1.9e-02	2.6e-02	2.4e-01	NA	8.1e-02
10	TCGA	Head and Neck Squamous Cell Carcinoma	0.0311	0.0162	1.7e-05	0.027	0.037	0.029	NA	0.031	5.1e-04	5.1e-05	3.1e-04	NA	1.8e-04
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0525	0.0334	1.5e-04	0.027	0.027	0.027	NA	0.021	4.2e-04	4.3e-04	5.0e-04	NA	1.7e-03
12	TCGA	Brain Lower Grade Glioma	0.0246	0.0173	1.7e-03	0.013	0.020	0.019	NA	0.014	1.0e-02	2.3e-03	2.5e-03	NA	9.5e-03
13	TCGA	Lung Adenocarcinoma	0.0401	0.0217	5.9e-05	0.037	0.034	0.028	NA	0.034	3.4e-05	7.2e-05	2.6e-04	NA	7.0e-05
14	TCGA	Lung Squamous Cell Carcinoma	0.0306	0.0190	3.0e-04	0.017	0.030	0.028	NA	0.024	4.2e-03	2.3e-04	3.3e-04	NA	8.2e-04
15	TCGA	Pancreatic Adenocarcinoma	0.1830	0.0950	4.3e-03	-0.006	0.064	0.064	NA	0.012	6.8e-01	1.1e-03	1.1e-03	NA	9.5e-02
16	TCGA	Prostate Adenocarcinoma	0.0221	0.0143	4.8e-03	0.015	0.005	-0.001	NA	0.004	8.4e-03	9.8e-02	4.4e-01	NA	1.1e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Fasting Glucose	15.5	18.6	46.9	1.6	4.1	4.2	4.6	0.9	6.8	6.2	4.5	5.2	3.2	2.5	5.2	4.1	3.4	3.8	4.7
Risk taking	12.9	18.9	28.9	-0.4	-5.3	-4.9	-4.2	-5.2	-1.2	-3.8	-4.1	-3.5	-4.9	-5.4	-4.7	-5.0	-5.4	-2.2	-5.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	8.6	10.1	17.2	-0.4	-3.1	-3.1	-3.0	-2.2	-4.0	-4.2	-3.5	-3.2	-3.1	-2.8	-3.8	-3.6	-3.2	-2.0	-3.6
Medication for hormone replacement therapy	8.5	9.5	13.2	-2.5	-3.5	-3.5	-3.3	-3.5	-2.5	-3.2	-3.0	-2.5	-3.2	-2.6	-3.6	-2.9	-3.2	-2.3	-3.4
Triglycerides	8.4	13.8	118.8	0.6	1.6	1.6	0.1	6.0	-10.9	-5.8	-0.2	-3.6	2.0	2.3	-1.4	-0.0	1.6	-0.4	-0.4
Medication for cholesterol	5.1	7.8	25.5	-0.9	2.5	2.6	2.5	1.7	5.0	2.7	3.2	2.0	2.4	1.6	3.7	2.8	2.4	3.1	2.9
Age at First Birth	5.0	7.3	11.9	0.8	3.1	2.9	2.6	3.1	-0.4	1.7	3.0	2.2	3.2	3.5	2.9	3.4	3.3	1.4	3.2
Heart attack/myocardial infarction (self-reported)	5.0	6.4	12.0	-2.3	-2.9	-2.9	-2.7	-3.5	-1.1	-2.2	-2.1	-1.2	-2.9	-2.9	-2.8	-2.2	-2.8	-2.2	-2.6
Medication: Amlodipine	4.9	6.9	12.2	1.1	-2.5	-2.8	-2.3	-3.4	-3.5	-2.0	-3.3	-0.7	-2.9	-2.0	-3.1	-2.7	-2.8	-2.9	-2.3
Medication: Atorvastatin	4.9	6.1	18.7	-2.1	-1.8	-1.9	-1.9	-0.7	-4.3	-3.4	-2.7	-3.7	-1.5	-1.3	-2.7	-2.2	-1.4	-2.5	-2.6
Intelligence (Savage-Jansen 2018)	4.8	14.7	23.1	3.4	3.8	3.5	3.6	4.8	1.2	3.7	4.2	4.5	3.5	3.6	4.5	4.2	3.6	3.5	4.4
Qualifications: O levels/GCSEs or equivalent	4.6	7.3	11.1	2.0	3.0	2.8	2.9	3.3	0.6	3.2	2.9	3.1	2.4	2.2	3.1	2.5	2.3	2.7	3.0
Schizophrenia (2018)	4.5	9.4	20.7	-4.4	-3.1	-3.0	-3.4	-3.0	1.1	-4.6	-3.0	-3.8	-2.6	-2.8	-2.3	-3.0	-2.5	-1.6	-3.0
Schizophrenia (2014)	4.4	9.7	22.4	-4.5	-3.1	-3.0	-3.4	-2.8	0.6	-4.7	-2.9	-3.9	-2.6	-2.9	-2.5	-3.2	-2.7	-1.4	-3.2
Average weekly spirits intake	4.4	5.4	9.4	-0.3	-2.3	-2.3	-2.5	-1.8	-2.1	-2.6	-3.1	-2.6	-2.3	-1.9	-2.8	-2.4	-2.5	-1.7	-2.7
Fluid intelligence score	4.4	9.0	16.4	2.2	3.1	3.0	3.4	3.6	1.6	4.0	3.0	3.5	2.6	2.5	3.3	3.1	2.5	2.3	3.4
Qualifications: A levels/AS levels or equivalent	4.3	9.4	17.6	1.5	3.3	3.0	3.5	2.9	2.2	3.4	3.6	4.2	2.4	1.8	3.5	2.9	2.3	3.5	3.7
Heart attack	4.1	5.2	10.8	-1.9	-2.6	-2.6	-2.4	-3.3	-1.1	-1.9	-1.9	-0.8	-2.6	-2.6	-2.6	-2.1	-2.5	-2.0	-2.4
Overall health rating	4.1	8.9	17.6	-1.7	-2.7	-2.4	-2.6	-3.6	-3.2	-4.2	-2.9	-3.6	-2.5	-2.6	-3.6	-3.1	-2.7	-1.7	-3.3
Bipolar Disorder (2011)	4.0	3.9	12.0	-2.5	-1.6	-1.4	-1.6	-2.1	-2.1	-3.5	-1.5	-1.5	-1.6	-2.2	-1.7	-2.5	-1.9	0.2	-1.8
Trunk fat percentage	4.0	15.8	25.7	-1.6	-4.4	-4.0	-4.2	-3.7	-1.4	-5.1	-4.4	-4.2	-4.0	-3.9	-4.5	-4.5	-4.0	-3.5	-4.4
Worry too long after embarrassment	3.9	6.6	10.1	3.2	2.3	2.2	2.4	3.0	1.8	2.0	2.9	3.0	2.6	2.5	2.6	2.8	2.8	1.4	2.8
Knee pain experienced in last month	3.9	6.1	8.9	-0.8	-2.6	-2.6	-2.4	-3.0	-1.8	-2.5	-2.9	-2.1	-2.7	-2.1	-3.0	-2.3	-2.7	-2.6	-2.6
Ever used hormone-replacement therapy (HRT)	3.8	4.8	9.3	-0.9	-2.2	-2.4	-2.4	-2.8	0.4	-1.4	-3.0	-2.0	-2.4	-1.4	-2.7	-1.9	-2.4	-2.7	-2.3
Schizophrenia vs Biploar Disorder	3.7	4.9	8.5	-1.8	-2.0	-2.0	-2.5	-2.7	2.7	-0.7	-2.8	-2.9	-1.7	-1.8	-1.7	-2.6	-1.4	-2.3	-2.5
Verbal and Numeric Reasoning (VNR)	3.7	9.0	16.7	2.9	2.8	2.7	3.2	3.4	1.0	3.5	3.2	4.1	2.5	2.5	3.5	3.1	2.5	2.4	3.4
LDL Cholesterol	3.7	5.8	15.6	0.9	2.7	2.6	2.0	4.0	0.9	1.1	2.3	1.6	2.8	2.9	2.6	3.1	2.9	0.9	2.6
Number of incorrect matches in round	3.7	6.2	8.9	-0.9	-2.8	-2.6	-2.8	-2.2	-0.3	-3.0	-2.9	-2.0	-2.6	-2.8	-2.6	-2.9	-2.6	-1.9	-2.9
Unable to work because of sickness or disability	3.7	4.8	7.1	0.0	-2.3	-2.2	-2.5	-2.5	0.1	-2.6	-2.5	-2.0	-2.6	-2.7	-2.3	-2.1	-2.7	-1.2	-2.2
Alcohol intake frequency.	3.6	8.3	51.7	-1.4	-0.6	-0.4	-1.3	1.7	-7.2	-4.9	-3.1	-4.0	-0.9	-0.3	-3.0	-2.0	-1.0	-2.0	-2.2
Medication for pain relief, constipation, heartburn	3.5	6.0	30.1	-2.0	2.3	2.4	1.6	2.0	5.5	1.5	2.1	0.8	2.3	1.2	3.1	1.6	2.2	3.0	2.1
Pain experienced in last month	3.5	5.8	10.0	1.0	2.3	1.9	1.4	3.2	3.1	2.4	2.4	2.8	2.2	2.2	3.0	2.7	2.6	1.5	2.6
Bipolar Disorder or Schizophrenia	3.3	8.1	28.7	-4.5	-2.8	-2.6	-2.5	-2.6	-0.5	-5.4	-2.3	-3.2	-2.4	-2.6	-2.2	-2.5	-2.7	-0.8	-2.6
Vitamin and mineral supplements	3.3	4.5	10.2	-0.6	2.4	2.4	2.1	1.8	3.2	2.5	1.8	2.1	1.7	1.6	2.5	1.9	1.6	2.2	2.4
Diverticular disease/diverticulitis (self-reported)	3.3	4.0	7.6	2.3	2.3	2.3	2.7	1.9	-0.4	2.1	2.1	1.3	2.1	1.8	1.8	1.2	1.5	2.8	1.9
Osteoarthritis (self-reported)	3.3	4.3	7.2	-1.9	-1.9	-1.8	-1.9	-2.6	-2.4	-1.0	-2.6	-0.9	-2.4	-1.8	-2.7	-2.1	-2.5	-1.9	-1.9
High cholesterol (Self-reported)	3.3	5.9	42.2	-0.8	-0.4	-0.3	-1.1	0.8	-6.5	-4.1	-2.1	-4.0	0.1	-0.0	-2.2	-1.7	-0.1	-0.7	-1.9
Medication: Paracetamol	3.3	5.1	19.1	-1.2	-2.0	-2.0	-1.4	-2.9	-4.4	-2.6	-2.0	-1.7	-2.0	-1.5	-2.8	-1.8	-2.3	-1.5	-2.1
Diabetes (self-reported)	3.2	5.0	10.3	-0.7	-2.8	-2.8	-2.7	-3.2	0.7	0.5	-2.1	0.5	-3.2	-2.4	-2.0	-1.0	-2.7	-3.2	-1.8
Falls in the last year	3.0	4.1	8.2	-1.4	-1.9	-1.8	-2.1	-2.2	-2.1	-2.9	-2.3	-1.7	-2.0	-1.8	-2.4	-1.6	-1.9	-2.0	-2.0
Neck or shoulder pain in last month	3.0	4.3	9.1	-2.1	-1.9	-1.8	-1.8	-3.0	-1.5	-1.5	-2.3	-2.8	-1.6	-1.3	-2.5	-2.2	-1.8	-1.8	-2.4
Friendships satisfaction	3.0	3.7	6.3	0.1	2.3	2.2	2.2	1.7	-0.3	0.5	2.0	1.2	2.2	2.4	2.2	2.5	2.1	1.8	2.5
Stomach or abdominal pain in last month	2.9	3.6	8.8	0.1	-2.0	-1.8	-1.6	-0.7	-3.0	-2.1	-1.8	-2.5	-1.4	-1.1	-2.5	-1.9	-1.5	-1.9	-2.4
Trunk fat mass	2.9	12.3	18.0	-1.6	-4.1	-3.8	-3.6	-4.2	0.6	-3.9	-3.5	-3.3	-3.7	-3.6	-3.8	-3.9	-3.6	-3.1	-3.8
Diabetes diagnosed by doctor	2.9	4.7	11.2	-0.7	-2.7	-2.8	-2.6	-3.3	1.2	0.5	-1.9	0.5	-3.1	-2.3	-2.0	-1.0	-2.7	-2.6	-1.6
Vascular/heart problems diagnosed by doctor	2.9	7.9	17.2	-1.7	2.6	2.7	2.7	2.6	4.1	2.7	3.5	1.9	2.4	1.4	3.5	2.6	2.2	4.2	2.6
Waist Hip Ratio (WHR)	2.8	12.5	31.6	-4.0	-2.8	-2.3	-2.6	-4.1	0.2	-4.6	-3.6	-5.6	-2.6	-3.7	-3.4	-4.6	-3.5	0.9	-3.8
Medication: Blood pressure	2.8	5.3	11.2	3.4	-2.1	-2.3	-2.1	-1.6	-3.1	-1.7	-2.7	-0.8	-2.0	-1.0	-2.8	-2.2	-1.8	-3.3	-2.1
Blood White Count	2.7	19.9	58.7	2.6	5.2	5.0	4.3	7.0	-7.7	-0.4	3.1	1.4	4.8	5.7	2.5	4.5	4.5	1.6	4.1
Multivitamins +/- minerals	2.7	3.5	6.1	1.1	-2.1	-2.1	-2.2	-1.5	-2.5	-2.1	-1.8	-1.6	-1.6	-1.3	-2.1	-1.7	-1.5	-1.9	-2.2
Pain all over the body in last month	2.7	2.9	6.8	-0.7	-1.5	-1.5	-1.4	-2.6	-1.4	-1.7	-2.0	-1.8	-1.5	-1.2	-2.2	-1.8	-1.6	-2.0	-1.7
Loud music exposure frequency	2.7	2.9	5.2	-0.9	-1.9	-1.8	-1.8	-1.8	0.4	-1.1	-2.0	-2.3	-1.5	-1.7	-1.6	-2.2	-1.5	-1.6	-2.1
Medication: Paracetamol	2.7	4.5	22.4	-0.4	-1.9	-2.0	-1.3	-2.3	-4.7	-2.3	-1.8	-1.5	-1.7	-0.8	-2.7	-1.4	-1.8	-2.0	-1.9
Body fat percentage	2.7	10.5	18.7	-1.0	-3.5	-3.2	-3.3	-2.9	-1.1	-4.3	-3.6	-3.5	-3.2	-3.1	-3.8	-3.8	-3.2	-2.7	-3.6
HDL Cholesterol	2.6	4.4	10.2	-1.1	-2.4	-2.1	-2.0	-1.8	-0.4	-1.5	-2.5	-3.2	-1.8	-1.6	-2.5	-2.4	-1.8	-1.8	-2.8
Type 2 Diabetes (T2D) (2018)	2.6	4.9	15.3	-1.5	-2.6	-2.6	-2.6	-3.9	2.5	0.3	-1.8	0.0	-2.8	-2.4	-1.7	-1.2	-2.4	-2.2	-1.7
Waist circumference	2.6	9.6	19.0	-0.4	-3.6	-3.3	-2.8	-4.4	0.6	-3.3	-3.1	-2.9	-3.2	-3.2	-3.5	-3.3	-3.4	-2.6	-3.2
Gout (self-reported)	2.5	3.4	33.5	-0.1	0.8	1.0	0.4	2.6	-5.8	-3.0	-0.6	-1.0	0.4	0.4	-1.1	-0.6	0.1	0.3	-0.2
Myopia	2.5	3.6	6.9	-0.5	-2.0	-2.1	-2.6	-1.0	-1.6	-1.3	-2.6	-2.3	-1.8	-1.3	-2.2	-1.7	-1.8	-2.0	-2.2
Chronotype (morning person)	2.4	5.5	8.1	1.1	2.7	2.7	2.8	2.7	0.5	2.5	2.4	1.5	2.8	2.8	2.4	2.1	2.7	2.2	2.2
Angina	2.4	3.1	6.3	-0.2	-1.3	-1.3	-1.4	-2.5	-1.0	-2.3	-2.3	-1.4	-1.8	-2.0	-2.1	-2.5	-2.1	-0.2	-1.7
Medication: Metformin	2.4	3.4	7.4	-0.9	-2.3	-2.2	-2.1	-2.7	1.9	-0.3	-1.6	-0.7	-2.5	-2.1	-1.6	-0.9	-2.3	-1.7	-1.5
Hayfever, allergic rhinitis or eczema	2.4	5.1	13.0	1.9	2.7	2.5	2.1	3.6	-1.6	2.3	1.9	1.6	2.5	2.9	1.9	1.8	2.6	0.9	2.1
Had menopause	2.4	3.0	9.7	-1.0	-1.3	-1.5	-1.7	-2.6	3.1	-0.7	-2.0	-1.4	-1.7	-1.9	-1.1	-2.1	-1.7	-0.3	-1.5
Number of treatments/medications taken	2.3	4.1	26.6	1.4	-1.5	-1.6	-1.2	-1.3	-5.2	-1.5	-1.8	-0.5	-1.8	-1.2	-2.7	-1.5	-1.9	-2.0	-1.6
Medication: Cholesterol lowering	2.3	3.6	16.2	-0.5	-1.0	-1.0	-1.6	-0.7	-4.0	-2.4	-2.4	-3.0	-0.8	-0.6	-2.3	-1.8	-1.1	-1.2	-1.9
High blood pressure (siblings)	2.3	3.3	14.8	1.2	-1.1	-1.1	-1.5	-0.0	-3.9	-0.6	-2.4	-2.5	-0.7	0.0	-2.1	-1.7	-0.7	-2.7	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.3	3.0	7.7	-1.0	-1.4	-1.2	-1.4	-2.4	0.2	-2.8	-1.6	-2.4	-1.4	-1.7	-1.7	-1.9	-2.1	1.0	-1.7
Ulcerative Colitis	2.2	3.2	9.2	-0.4	-1.7	-1.8	-1.5	-2.2	-3.0	-2.2	-1.8	-1.3	-1.7	-1.3	-1.9	-1.7	-1.7	-1.3	-1.8
Cardiovascular Disease	2.2	7.3	32.8	1.7	-2.0	-1.8	-2.2	-0.8	-5.7	-2.7	-3.1	-2.6	-1.7	-1.3	-3.3	-3.1	-1.8	-3.1	-2.7
Tinnitus: Yes, but not now, but have in the past	2.2	2.3	5.3	-0.1	-1.8	-1.6	-1.6	-2.3	0.3	-1.3	-1.1	-1.2	-1.8	-2.2	-1.4	-1.5	-1.8	-0.3	-1.5
Commuting to job workplace: Public transport	2.2	2.6	4.9	0.5	1.4	1.2	1.1	2.2	1.8	1.5	1.8	1.9	1.6	1.8	1.7	2.1	1.7	0.7	1.8
Blood Platelet Count	2.1	24.6	222.0	-1.0	-1.8	-1.7	-2.9	2.2	-14.9	-6.3	-4.4	-5.3	-1.5	-0.1	-5.0	-2.8	-1.9	-3.3	-3.6
Medication: Allopurinol	2.1	2.8	21.4	0.4	1.5	1.6	0.7	3.0	-4.6	-1.6	0.3	0.0	1.2	1.6	-0.1	0.5	1.0	0.6	0.8
High blood pressure	2.0	5.7	16.0	2.3	-2.0	-2.1	-2.1	-1.9	-4.0	-2.1	-2.9	-1.6	-1.7	-0.7	-2.9	-2.1	-1.6	-3.9	-2.0
Hearing difficulty/problems with background noise	2.0	3.2	5.6	-1.1	-1.7	-1.7	-1.4	-2.4	-1.9	-1.0	-2.1	-0.7	-1.9	-1.9	-2.2	-2.2	-1.7	-2.1	-1.7
Qualifications: None of the above	2.0	4.3	7.7	0.1	-2.5	-2.3	-2.4	-1.8	-0.4	-1.8	-2.2	-2.8	-1.9	-1.8	-2.4	-2.3	-1.8	-2.1	-2.7
Whole body fat mass	2.0	8.4	12.4	-1.3	-3.4	-3.1	-2.9	-3.5	0.7	-3.2	-2.8	-2.8	-3.0	-3.0	-3.1	-3.2	-2.9	-2.8	-3.2
Commuting to job workplace: Walk	2.0	2.2	6.0	1.4	1.3	1.1	0.8	2.1	-0.0	1.3	0.6	0.3	1.7	2.5	1.2	2.0	2.2	-1.4	1.3
Medication: Lansoprazole	1.9	2.2	5.1	0.4	-1.2	-1.1	-0.7	-2.2	-1.1	-1.2	-1.9	-1.5	-1.6	-1.6	-1.9	-1.8	-1.9	-0.5	-1.5
Impedance of arm (left)	1.9	8.7	19.0	-2.5	-2.2	-2.4	-3.6	0.3	-4.0	-4.4	-3.6	-4.2	-1.9	-1.5	-3.0	-2.9	-1.8	-2.4	-3.2
Age at first live birth	1.9	3.3	7.2	0.1	2.2	2.0	2.3	1.5	0.3	1.1	2.0	1.8	1.9	1.5	2.1	1.7	1.6	2.7	2.2
Angina (self-reported)	1.9	2.5	5.2	-0.1	-1.1	-1.1	-1.2	-2.2	-0.7	-2.3	-2.0	-1.3	-1.7	-1.9	-1.8	-2.2	-1.9	-0.1	-1.5
Chronic bronchitis/emphysema (father)	1.8	2.2	8.6	-1.5	-1.3	-1.0	-1.1	-1.6	-1.0	-2.9	-1.1	-1.4	-1.3	-1.7	-1.4	-1.4	-1.4	-0.6	-1.4
Medication: Simvastatin	1.8	2.7	12.0	1.3	-1.0	-1.0	-1.3	-0.4	-3.5	-2.4	-1.7	-2.3	-0.7	-0.3	-2.1	-1.5	-0.9	-0.9	-1.7
Average weekly beer plus cider intake	1.8	2.6	4.5	-0.1	-1.9	-1.9	-2.1	-2.1	1.4	-1.8	-1.3	-1.6	-1.6	-2.1	-1.1	-1.7	-1.5	-0.5	-1.7
Primary Biliary Cirrhosis	1.7	2.5	3.8	-0.9	-1.8	-1.8	-1.7	-1.1	-1.4	-1.9	-1.4	-1.1	-1.9	-1.6	-1.9	-1.4	-1.7	-1.6	-1.5
Hypothyroidism (self reported)	1.7	3.9	6.8	1.5	2.1	2.0	1.9	2.2	1.0	2.4	2.1	2.6	1.9	2.0	2.0	2.0	2.1	0.6	2.3
Tense / ‘highly strung’	1.7	2.9	5.4	-0.4	-1.7	-1.6	-1.7	-2.0	-1.3	-2.3	-1.8	-2.1	-1.3	-1.6	-1.9	-2.0	-1.5	-0.5	-2.1
Hypertension (Self-reported)	1.7	4.8	15.3	2.6	-1.7	-1.9	-1.9	-1.6	-3.9	-1.6	-2.6	-1.0	-1.6	-0.5	-2.6	-1.7	-1.4	-3.8	-1.6
Medication: Levothyroxine sodium	1.6	2.7	4.8	0.8	1.7	1.5	1.7	1.5	-0.2	2.1	1.7	2.2	1.6	2.1	1.4	2.1	1.7	0.0	2.0
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.9	5.0	-0.2	1.6	1.6	1.8	-0.2	0.9	1.4	1.3	2.2	0.6	0.4	1.5	1.1	0.4	2.2	1.7
Hearing aid user	1.6	1.8	5.5	0.4	1.7	1.8	1.5	0.9	1.3	1.0	0.9	-0.4	1.9	1.1	1.5	-0.1	1.6	2.3	0.8
Major Depression (MDD)	1.5	1.8	3.8	-2.0	-1.3	-1.4	-1.4	-1.7	0.3	-1.6	-1.5	-1.8	-0.8	-0.5	-1.4	-1.3	-1.0	-1.1	-1.2
Ovarian Cancer	1.5	1.9	5.6	1.8	1.1	1.2	1.8	1.2	0.1	1.1	2.0	2.4	0.6	0.2	1.2	1.1	0.3	2.1	1.5
High blood pressure (mother)	1.5	2.0	16.3	4.0	0.3	0.2	0.1	0.4	-3.7	0.4	0.1	0.7	0.2	0.8	-0.2	0.4	0.2	-0.7	0.4
Had other major operations	1.5	1.9	5.2	-1.4	-0.9	-0.8	-0.4	-1.9	-2.1	-1.8	-1.6	-2.3	-0.4	0.1	-1.5	-0.9	-0.8	-1.2	-1.3
Hip circumference	1.5	6.3	16.2	0.3	-3.3	-3.2	-2.6	-3.1	-0.2	-2.0	-2.3	-1.0	-2.9	-2.1	-2.8	-1.9	-2.5	-4.0	-2.4
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	6.2	0.6	-1.9	-1.8	-1.3	-1.2	-1.6	-2.5	-1.1	-0.4	-1.7	-1.5	-1.9	-1.4	-1.7	-1.4	-1.5
Happiness	1.5	1.8	4.5	0.4	1.4	0.9	0.9	2.1	-1.0	0.7	1.0	1.2	1.2	2.1	1.1	2.1	1.4	-0.1	1.7
Pulse wave reflection index	1.5	1.9	5.1	-0.4	-1.8	-1.8	-1.0	-2.3	-0.1	-1.2	-0.8	-0.1	-1.7	-1.9	-1.4	-1.3	-1.9	-0.5	-1.3
Shortness of breath walking on level ground	1.5	1.8	2.9	-0.5	-1.7	-1.6	-1.6	-1.5	-1.1	-1.5	-1.1	-0.8	-1.6	-1.4	-1.4	-0.8	-1.2	-1.6	-1.5
Medication: Aspirin	1.5	1.9	3.7	1.3	-1.4	-1.5	-1.6	-0.9	-1.9	-0.7	-1.6	-0.2	-1.6	-0.9	-1.8	-1.1	-1.4	-1.9	-1.2
Weight	1.4	6.9	17.8	-1.1	-3.4	-3.1	-2.4	-4.2	2.5	-1.8	-1.9	-1.2	-2.9	-2.9	-2.5	-2.4	-2.7	-2.8	-2.6
Alcohol intake versus 10 years previously	1.4	2.1	12.7	-0.6	-0.6	-0.6	-1.3	0.3	-3.6	-1.2	-1.6	-1.9	-0.8	0.0	-1.8	-0.5	-0.4	-2.3	-1.2
Worrier / anxious feelings	1.4	2.6	4.8	1.7	1.8	1.6	1.8	1.7	0.2	1.7	1.5	0.5	2.0	2.2	1.5	1.7	2.1	0.7	1.8
Prospective memory result	1.4	1.8	3.7	-1.0	-1.3	-1.3	-1.4	-1.6	-0.1	-1.2	-1.4	-1.9	-0.9	-0.9	-1.4	-1.6	-0.7	-1.6	-1.7
Number of children fathered	1.4	1.5	5.2	0.4	-1.2	-1.2	-0.5	-2.3	-0.4	-1.7	-1.1	-0.4	-1.6	-1.6	-1.2	-1.3	-1.8	0.1	-0.7
Emphysema/chronic bronchitis	1.4	1.6	3.3	1.8	1.1	1.0	1.3	0.9	1.1	1.4	1.5	1.3	1.2	1.2	1.4	0.9	0.9	1.3	1.4
Arm fat percentage (left)	1.4	5.7	11.6	0.0	-2.8	-2.5	-2.4	-2.1	-0.5	-3.4	-2.4	-2.1	-2.5	-2.5	-2.7	-2.7	-2.4	-2.4	-2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	2.9	7.1	1.2	2.0	1.9	2.2	1.0	1.0	1.4	1.9	2.0	1.5	1.0	2.0	1.4	1.1	2.7	1.9
Tinnitus: Yes, now most or all of the time	1.4	1.6	3.3	0.0	1.6	1.6	1.8	1.1	0.2	1.4	1.2	1.0	1.2	1.1	1.3	1.4	1.1	1.1	1.6
Cholesterol lowering medication	1.4	2.1	13.1	0.4	-0.6	-0.5	-0.8	0.6	-3.6	-2.5	-1.2	-1.6	-0.7	-0.8	-1.6	-1.5	-0.7	-0.3	-1.4
Depressed Affect (Nagel 2018)	1.3	2.7	6.9	2.3	-1.6	-1.7	-1.4	-1.0	-2.6	-1.8	-1.4	-0.7	-1.5	-1.0	-2.0	-0.9	-1.4	-2.2	-1.3
Blood Red Count	1.3	12.1	28.4	0.8	3.4	3.4	4.4	1.1	2.3	3.8	4.5	5.3	3.0	2.9	3.7	3.9	2.7	3.2	4.3
Diabetes (father)	1.3	1.6	5.9	-0.0	0.8	0.8	1.1	0.8	2.4	0.8	1.5	0.9	1.3	1.4	1.6	1.8	1.6	-0.4	1.2
Impedance of arm (right)	1.3	5.8	16.3	-2.0	-1.4	-1.6	-3.0	1.4	-3.8	-4.0	-2.9	-3.4	-1.2	-0.4	-2.2	-1.7	-0.7	-2.8	-2.2
Health satisfaction	1.3	1.7	5.2	1.6	-1.1	-1.3	-1.2	-0.5	-2.3	-1.5	-1.1	-2.2	-0.4	-0.3	-1.3	-0.9	-0.3	-1.3	-1.4
Pulse rate, automated reading	1.3	4.2	15.4	-3.6	1.1	1.2	-0.0	3.0	-3.7	-3.9	0.0	-2.3	1.4	1.5	-0.2	0.4	1.6	-0.0	-0.1
Commuting to job workplace: Car/motor vehicle	1.3	1.5	4.3	0.3	-0.6	-0.6	-1.0	-1.9	-2.1	-0.3	-1.7	-1.4	-1.1	-1.0	-1.4	-1.4	-1.4	-0.2	-1.1
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	6.1	-0.4	1.0	0.9	1.1	1.1	1.1	2.0	1.4	2.5	0.6	0.4	1.6	1.0	0.8	1.0	1.4
Supplements: Vitamin C	1.3	1.5	2.4	-0.3	-1.5	-1.5	-0.7	-1.5	-1.1	-0.6	-1.0	-1.4	-1.1	-1.2	-1.4	-1.5	-1.3	-0.9	-1.6
Impedance of whole body	1.3	6.6	19.4	-2.3	-1.4	-1.5	-2.7	0.8	-4.1	-3.8	-3.2	-4.4	-1.2	-1.0	-2.5	-2.7	-1.3	-1.1	-2.8
Depression (Nagel 2018)	1.2	1.9	6.4	0.7	-1.2	-1.4	-1.5	-0.1	-2.1	-1.4	-1.6	-1.6	-0.7	-0.2	-1.6	-0.6	-0.5	-2.5	-1.5
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	3.7	0.5	-1.2	-1.2	-1.3	0.0	-1.0	-1.9	-1.3	-1.7	-1.0	-1.1	-1.2	-1.2	-1.0	-0.5	-1.4
Allergy	1.2	2.7	4.6	-0.6	-2.1	-2.0	-1.5	-2.1	0.9	-1.6	-1.6	-0.8	-2.1	-2.1	-1.6	-1.3	-1.9	-1.5	-1.7
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	13.6	-1.1	0.5	0.6	1.0	0.8	3.7	0.8	2.0	1.1	0.8	-0.0	1.9	1.0	0.9	1.7	0.8
Number of full sisters	1.2	1.4	3.5	-0.8	1.5	1.5	1.2	0.6	1.4	0.6	1.4	0.7	1.2	0.7	1.3	1.0	1.0	1.9	1.3
Arm fat mass (left)	1.2	5.1	8.4	-0.2	-2.9	-2.6	-2.1	-2.9	0.9	-2.5	-1.9	-1.6	-2.4	-2.5	-2.4	-2.4	-2.3	-2.4	-2.3
Miserableness	1.2	2.0	3.8	2.0	1.3	1.2	1.8	1.8	-1.9	0.2	1.6	1.7	1.1	1.5	0.7	1.5	1.0	0.5	1.5
Leg fat percentage (left)	1.2	4.3	8.4	-0.4	-2.1	-1.8	-1.7	-2.1	-0.6	-2.9	-2.3	-2.5	-1.9	-2.0	-2.5	-2.6	-2.1	-1.4	-2.4
Ulcerative Colitis (UC)	1.1	2.0	8.2	-0.2	-1.4	-1.5	-1.0	-1.5	-2.9	-1.4	-1.2	-0.1	-1.4	-1.2	-1.5	-1.1	-1.2	-1.8	-1.3
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	11.5	1.8	-0.9	-0.9	-0.3	-1.0	-3.4	-0.9	-0.3	0.3	-0.9	-0.7	-1.1	-0.5	-1.1	-0.6	-0.6
Eye problems/disorders: None of the above	1.1	1.2	2.6	-0.7	-1.4	-1.5	-1.6	-0.4	1.5	0.1	-0.8	-0.2	-1.3	-1.5	-0.5	-1.4	-1.1	-0.7	-1.2
Suffer from ‘nerves’	1.1	1.8	7.5	2.7	1.1	0.9	0.8	1.6	0.1	2.0	0.8	1.2	1.0	1.5	1.0	1.3	1.3	0.1	1.3
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.0	1.7	-1.5	-1.4	-0.7	-1.1	-1.5	-0.4	-0.7	-1.0	-0.9	-1.2	-1.3	-1.5	-1.1	-0.3	-1.6
Medication: Bendroflumethiazide	1.1	1.6	10.7	3.3	0.0	-0.3	-0.4	0.0	-2.8	-0.2	-1.5	-0.7	-0.0	1.0	-1.1	-0.6	-0.1	-1.6	-0.3
Medication: Lisinopril	1.1	1.4	3.7	0.4	-1.4	-1.5	-1.2	-1.5	-0.5	0.2	-1.4	-0.1	-1.4	-0.9	-1.5	-0.8	-1.4	-1.9	-1.1
Leg fat mass (left)	1.1	4.2	9.2	-0.6	-2.4	-2.1	-1.8	-3.0	1.3	-2.1	-1.9	-1.9	-2.0	-2.1	-2.2	-2.3	-2.1	-1.8	-2.2
Allergy or Eczema	1.0	2.7	7.0	1.1	2.1	1.9	1.7	2.6	-2.1	1.6	1.0	1.2	1.6	2.1	1.1	1.1	1.6	0.6	1.5
Sensitivity / hurt feelings	1.0	1.8	3.1	0.4	-1.7	-1.8	-1.0	-1.6	-1.3	-1.4	-1.1	-0.6	-1.4	-1.1	-1.4	-1.0	-1.3	-1.7	-1.4
Pulse rate	1.0	1.6	4.6	-2.0	1.5	1.7	0.8	2.1	-1.0	-1.1	0.7	-0.9	1.3	0.8	0.7	0.5	1.2	1.8	0.6
Illnesses of mother	1.0	1.2	9.6	-2.3	0.5	0.6	0.8	0.2	3.1	-0.2	0.8	0.8	0.2	-0.1	0.8	0.8	0.3	0.6	0.8
Arm fat mass (right)	1.0	4.3	7.2	-0.3	-2.7	-2.4	-2.0	-2.6	1.1	-2.4	-1.7	-1.4	-2.2	-2.2	-2.1	-2.1	-2.0	-2.5	-2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	2.7	0.1	-1.2	-1.4	-1.3	-1.1	-1.5	-1.3	-1.5	-1.3	-1.1	-0.7	-1.6	-1.2	-1.3	-0.8	-1.4
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	7.6	0.3	-0.5	-0.6	-0.4	-1.0	-2.8	-1.4	-1.2	-1.5	-0.7	-0.3	-1.6	-0.6	-1.0	-0.7	-0.8
Leg fat mass (right)	1.0	3.9	8.1	-0.6	-2.4	-2.1	-1.8	-2.8	1.3	-2.1	-1.8	-1.7	-2.0	-2.1	-2.1	-2.2	-2.0	-1.9	-2.1
Leg pain on walking	1.0	1.3	3.8	0.1	-1.1	-1.1	-1.0	-2.0	-0.4	-0.6	-1.2	-0.4	-1.5	-1.1	-1.3	-0.8	-1.5	-1.2	-1.0
Irritable Bowel Disease (IBD)	0.9	2.2	10.0	-1.0	-1.2	-1.4	-1.2	-0.7	-3.2	-1.9	-1.3	-0.7	-1.2	-1.2	-1.5	-1.4	-0.8	-1.9	-1.5
Prostate Cancer	0.9	1.3	3.8	-0.4	-1.2	-1.3	-1.1	-0.5	-1.4	-1.9	-1.1	-1.1	-1.2	-0.8	-1.4	-0.8	-1.5	-0.4	-1.0
Systolic Blood Pressure	0.9	4.7	34.3	5.9	0.4	0.1	0.0	1.2	-5.4	2.1	-0.5	1.4	0.0	1.3	-1.0	-0.2	-0.3	-0.8	0.3
Systolic blood pressure, automated reading	0.9	2.7	17.7	4.2	0.9	0.6	0.8	1.3	-3.1	1.8	0.5	1.8	0.8	1.6	0.2	0.8	0.7	-0.4	1.2
Medication: Ramipril	0.9	1.2	3.1	0.6	-0.6	-0.7	-0.8	-1.2	-1.8	0.2	-1.7	-0.3	-1.2	-0.7	-1.5	-0.9	-1.1	-1.6	-0.6
Arm fat percentage (right)	0.9	3.6	9.4	0.2	-2.2	-2.0	-2.0	-1.3	-0.4	-3.1	-1.9	-1.6	-1.9	-1.7	-2.1	-1.9	-1.6	-2.5	-1.9
Standing height	0.9	8.5	21.7	-3.6	-3.4	-3.4	-2.9	-4.7	3.8	-0.8	-2.0	-2.2	-2.7	-2.6	-2.2	-2.2	-2.4	-2.5	-3.0
Exposure to tobacco smoke at home	0.9	1.0	2.1	-1.1	-0.9	-0.9	-1.1	-1.0	-0.8	0.1	-1.4	-0.1	-1.2	-1.0	-1.2	-0.9	-1.2	-0.8	-0.9
Leg fat percentage (right)	0.9	3.3	7.5	-0.4	-1.9	-1.6	-1.6	-1.6	-0.6	-2.7	-2.0	-2.1	-1.7	-1.8	-2.2	-2.2	-1.8	-1.6	-2.1
Comparative height size at age 10	0.9	4.9	15.9	-0.9	-2.9	-2.9	-2.6	-3.1	4.0	-0.3	-1.2	-0.7	-2.2	-2.1	-1.4	-1.4	-1.7	-2.4	-2.2
Mother’s age at death	0.9	1.1	2.7	-1.3	-1.2	-1.5	-1.6	-0.8	0.9	-0.9	-1.0	-1.3	-0.8	-0.9	-0.4	-0.8	-0.6	-0.5	-1.1
Alcohol drinker status: Never	0.9	1.0	2.6	-0.8	-0.7	-0.5	0.0	-1.1	-0.8	-1.6	-0.9	-1.2	-0.8	-1.2	-1.2	-1.4	-1.2	0.0	-1.2
Age started oral contraceptive pill	0.9	1.2	4.1	-0.5	1.2	1.3	0.8	1.2	1.1	0.3	1.2	0.6	1.1	0.2	1.5	0.7	1.1	2.0	1.1
Bipolar Disorder (2018)	0.8	1.2	8.4	-1.7	-0.5	-0.4	0.1	-0.5	-2.2	-2.9	-0.0	-0.4	-0.6	-0.6	-0.6	-0.4	-1.1	0.6	-0.3
Neuroticism (2016)	0.8	1.1	2.7	0.2	-1.1	-1.2	-1.5	-0.8	-1.4	-0.5	-1.3	-1.2	-0.8	-0.1	-1.4	-0.5	-0.6	-1.6	-1.1
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.9	-1.0	-1.1	-0.7	-0.6	-1.3	1.7	-0.1	-0.6	-0.3	-1.0	-1.5	-0.8	-0.9	-1.1	-0.3	-0.9
Diabetes (mother)	0.8	1.0	2.9	0.7	-1.1	-1.1	-1.3	-0.9	1.7	0.7	-0.8	-0.2	-0.9	-1.1	-0.6	-1.1	-0.6	-0.8	-1.0
Leg predicted mass (left)	0.8	4.0	15.0	-0.9	-2.4	-2.2	-1.5	-3.9	3.8	0.0	-0.7	0.3	-2.1	-2.0	-1.2	-1.0	-1.7	-2.3	-1.3
Illnesses of siblings	0.8	1.2	5.9	-0.4	0.7	0.5	0.8	0.3	2.4	-0.2	1.4	0.7	0.8	0.6	1.5	1.3	0.8	1.5	1.1
Headache pain in last month	0.8	1.4	5.0	2.1	1.0	1.2	1.6	1.6	-2.2	0.5	0.9	0.3	1.1	1.0	0.6	0.4	0.9	0.3	0.7
Medication: Ibuprofen	0.8	1.0	8.1	2.2	-0.5	-0.4	-0.1	-0.0	-2.8	-0.9	-0.0	0.2	-0.4	-0.2	-0.7	-0.1	-0.6	-0.4	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	4.5	-2.1	0.4	0.5	0.5	-0.3	-1.9	-0.1	-0.9	-2.1	0.3	0.3	-0.8	-0.5	-0.3	0.4	-0.4
Medication: Aspirin	0.8	1.0	2.8	1.2	-0.9	-1.0	-1.0	-0.6	-1.7	-0.3	-1.2	-0.0	-1.0	-0.4	-1.3	-0.7	-0.9	-1.5	-0.7
Number of self-reported non-cancer illnesses	0.8	1.4	14.0	0.5	-0.1	0.0	-0.5	-0.1	-3.7	-1.1	-1.3	-0.8	-0.4	-0.0	-1.2	-0.5	-0.3	-1.5	-0.5
Eye problems/disorders: Glaucoma	0.8	0.9	2.5	-0.1	1.0	1.1	1.2	0.4	0.9	0.5	1.2	0.6	0.8	0.6	1.0	1.2	0.6	1.6	1.0
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.5	-0.2	-0.9	-1.0	-0.7	-1.3	-1.0	-0.6	-1.3	-0.2	-1.5	-0.5	-1.4	-0.3	-1.6	-1.2	-0.4
Number of operations (self-reported)	0.8	1.2	7.7	0.9	0.9	0.8	1.4	-0.4	-2.8	0.4	0.2	-0.2	0.8	1.8	-0.2	1.1	0.6	-0.5	0.8
Neuroticism (Nagel 2018)	0.7	1.6	2.7	1.6	-1.4	-1.5	-1.1	-1.4	-1.2	-1.4	-1.4	-1.5	-0.9	-0.6	-1.5	-0.8	-0.9	-1.4	-1.1
Smoking Status	0.7	1.8	3.6	-1.8	-1.1	-1.2	-1.8	-1.0	-0.6	-1.5	-1.5	-1.9	-0.9	-0.9	-1.4	-1.2	-0.8	-1.3	-1.5
Pack years adult smoking proportion	0.7	1.0	6.8	-1.4	-0.3	-0.0	-0.0	-0.2	-0.7	-1.4	-0.5	-2.6	0.6	0.7	-0.7	-0.4	0.5	-1.3	-0.9
Leg fat-free mass (left)	0.7	3.9	14.4	-0.8	-2.4	-2.2	-1.4	-3.8	3.8	0.1	-0.7	0.3	-2.0	-2.0	-1.1	-1.0	-1.7	-2.3	-1.2
Average weekly fortified wine intake	0.7	0.8	2.0	0.7	0.9	0.9	1.4	0.7	0.9	0.6	0.9	0.5	1.1	1.0	1.0	0.8	1.1	0.4	0.8
Serious illness, injury or assault to yourself	0.7	0.9	3.5	-0.9	-0.5	-0.4	-0.8	-1.4	-1.9	-1.2	-1.0	-0.8	-0.8	-0.4	-1.2	-0.2	-0.9	-0.5	-0.5
Mouth/teeth dental problems: Dentures	0.7	1.1	4.1	2.0	0.8	0.7	1.0	-0.0	-0.2	1.9	0.9	1.5	0.6	0.9	0.6	1.0	0.4	1.0	1.0
Pulse wave Arterial Stiffness index	0.7	0.8	3.2	-0.6	-0.7	-0.7	-0.0	-1.8	-0.7	-1.2	-0.5	0.2	-1.1	-1.2	-1.0	-0.9	-1.4	0.4	-0.4
Arm fat-free mass (right)	0.7	3.4	20.8	-0.7	-1.7	-1.5	-0.4	-4.1	4.6	1.2	-0.0	0.3	-1.4	-1.8	-0.5	-0.9	-1.6	-0.2	-0.9
Medication: Blood pressure	0.7	1.3	5.1	1.9	-0.4	-0.5	-0.6	-1.1	-2.3	-0.0	-1.6	-0.4	-0.7	0.2	-1.5	-0.5	-0.8	-1.9	-0.3
Migraine (self-reported)	0.7	0.9	8.8	1.6	-0.4	-0.7	-0.1	-0.5	-3.0	-0.4	-0.4	-0.6	-0.2	0.2	-0.6	-0.2	-0.6	0.4	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.8	0.8	1.1	1.1	1.2	0.6	0.5	0.3	0.9	0.2	1.0	0.5	1.1	0.4	0.7	1.7	0.8
Leg fat-free mass (right)	0.7	3.9	15.4	-0.7	-2.4	-2.2	-1.4	-3.9	3.7	0.1	-0.7	0.3	-2.0	-2.0	-1.1	-1.1	-1.8	-2.1	-1.2
Long-standing illness, disability or infirmity	0.7	1.1	2.9	1.0	-1.0	-0.9	-0.9	-1.1	-1.7	-1.1	-0.8	-0.1	-1.2	-0.9	-1.2	-0.4	-1.1	-1.3	-0.6
Leg predicted mass (right)	0.7	3.9	15.4	-0.7	-2.4	-2.2	-1.3	-3.9	3.8	0.2	-0.7	0.3	-2.1	-2.0	-1.1	-1.1	-1.8	-2.0	-1.2
Wears glasses or contact lenses	0.7	0.8	2.3	0.1	-0.9	-0.8	-0.6	-1.5	-0.6	-0.5	-0.8	0.1	-1.2	-1.5	-0.8	-0.8	-1.2	-0.3	-0.6
Fractured/broken bones in last 5 years	0.7	1.0	2.4	0.9	-0.9	-0.9	-0.9	-0.9	-1.3	-1.0	-1.0	-0.6	-1.0	-0.6	-1.3	-0.7	-1.0	-1.6	-0.7
Diastolic blood pressure, automated reading	0.7	2.3	13.1	3.6	1.0	0.8	0.8	1.0	-2.1	1.9	1.0	2.0	0.9	1.6	0.7	1.0	0.8	0.2	1.5
Breast Cancer	0.6	1.4	3.6	1.8	1.3	1.1	1.2	1.9	-0.8	1.0	1.1	1.1	0.8	1.1	0.9	1.4	1.0	0.4	1.3
Body Mass Index (BMI) (2010)	0.6	0.8	3.6	1.9	-0.9	-1.0	-1.2	-0.5	0.3	-1.1	-0.9	-1.1	-0.4	-0.3	-0.4	-0.7	-0.4	-0.6	-0.7
Coronary Artery Disease (CAD)	0.6	0.7	1.8	-1.3	-0.5	-0.3	-1.0	-0.1	-0.0	-1.1	-0.9	-1.1	-0.4	-0.5	-0.5	-1.0	-0.2	-1.2	-1.0
Crohns Disease (2012)	0.6	1.0	3.6	-1.1	-0.7	-0.7	-0.7	0.3	-1.9	-1.7	-1.0	-1.2	-0.5	0.0	-0.9	-0.3	-0.3	-1.6	-0.8
Height	0.6	10.9	34.6	-4.2	-3.5	-3.3	-2.9	-5.9	5.1	-0.6	-2.3	-2.7	-2.9	-3.3	-2.0	-2.8	-2.9	-1.2	-3.2
Neuroticism	0.6	1.5	8.2	2.5	-0.6	-0.8	-0.5	-0.0	-2.9	-0.7	-1.0	-1.3	0.0	0.8	-1.2	-0.2	0.2	-1.7	-0.8
Financial difficulties in last 2 years	0.6	0.8	2.3	1.5	-0.8	-0.9	-1.1	-0.6	-0.6	-1.3	-0.8	-1.3	-0.6	0.0	-1.0	-0.3	-0.7	-0.7	-0.6
Hair/balding pattern: Pattern 4	0.6	1.5	4.5	-1.5	-1.4	-1.2	-1.2	-2.1	0.9	-0.1	-0.9	-0.3	-1.3	-1.6	-1.0	-1.4	-1.4	-0.7	-1.2
Blood clot in the leg (DVT)	0.6	0.8	2.1	0.3	0.8	0.9	1.4	-0.3	-0.2	0.7	1.1	0.6	0.9	1.0	0.6	0.9	0.4	1.4	1.0
Glaucoma (self-reported)	0.6	0.7	1.8	0.4	1.0	1.1	1.1	0.7	0.7	-0.1	0.8	-0.4	1.0	1.1	0.7	1.3	0.9	0.7	0.9
Pulse wave peak to peak time	0.6	0.7	2.1	0.5	0.5	0.6	-0.1	1.4	0.9	1.3	0.3	-0.3	0.9	1.1	0.8	0.8	1.2	-0.5	0.3
Qualifications: College or University degree	0.6	2.0	4.5	0.4	1.4	1.3	1.1	1.0	0.4	1.3	1.8	2.1	1.0	0.6	1.7	1.6	1.1	2.1	1.7
Medication: Omeprazole	0.6	0.7	3.5	0.2	-0.8	-0.8	-0.5	-0.9	-0.7	-0.3	-0.9	-1.9	-0.5	-0.6	-0.9	-0.9	-0.6	-0.6	-1.1
Arm predicted mass (right)	0.6	3.2	19.3	-0.5	-1.7	-1.5	-0.3	-4.1	4.4	1.2	0.1	0.5	-1.4	-1.7	-0.5	-0.8	-1.5	-0.4	-0.8
Age at last live birth	0.6	0.8	2.8	-0.7	1.1	1.1	1.1	0.2	-0.0	-0.2	0.9	0.6	0.7	0.6	1.0	1.0	0.5	1.7	1.2
Illnesses of father: Heart disease	0.6	0.8	6.2	-1.7	0.4	0.6	-0.0	0.3	-2.5	-0.3	-0.6	-1.6	0.3	0.5	-0.6	0.0	0.1	-0.2	-0.3
Illnesses of siblings: Diabetes	0.6	0.7	3.4	-1.0	-0.4	-0.3	-0.2	-1.9	1.8	1.0	-0.4	0.8	-0.6	-1.1	0.0	-0.7	-0.4	-0.0	-0.2
Smoking status: Previous	0.6	0.8	3.8	-2.0	-0.5	-0.9	-1.3	-0.7	-0.9	-0.1	-1.1	-0.8	-0.4	0.3	-0.8	-0.3	-0.3	-1.4	-0.5
Eye problems/disorders: Cataract	0.6	0.7	5.5	-0.3	0.6	0.7	0.5	-0.0	-2.4	-0.6	0.0	0.8	0.2	0.8	-0.4	1.0	0.4	-1.1	0.6
Illnesses of father: None of the above (group 1)	0.6	0.7	3.5	1.9	-0.2	-0.5	-0.3	0.8	1.2	1.1	0.3	1.7	-0.4	-0.1	0.2	0.5	0.1	-0.8	0.4
Whole body water mass	0.6	3.1	23.4	-0.5	-1.6	-1.5	-0.4	-3.6	4.8	1.3	0.4	1.0	-1.2	-1.3	-0.2	-0.2	-1.1	-1.0	-0.4
Financial situation satisfaction	0.6	0.7	3.9	1.4	-0.5	-0.8	-0.3	-0.2	-1.5	0.6	-0.7	0.6	-0.6	0.2	-0.8	0.0	-0.4	-2.0	-0.1
Basal metabolic rate	0.6	3.3	18.0	-0.7	-2.0	-1.8	-0.9	-3.8	4.2	0.6	-0.1	0.5	-1.6	-1.7	-0.7	-0.7	-1.4	-1.4	-0.9
Irritability	0.6	1.0	2.7	-0.3	-1.0	-1.1	-0.6	-1.6	-0.9	-1.6	-0.9	-0.8	-0.8	-1.1	-0.9	-1.3	-0.9	-0.1	-1.1
Pack years of smoking	0.6	0.8	5.5	-1.1	-0.1	0.1	0.0	-0.0	-0.3	-1.1	-0.4	-2.4	0.8	1.1	-0.4	-0.1	0.9	-1.4	-0.6
HbA1C	0.5	0.6	2.4	-0.7	-0.8	-0.9	-0.6	-0.7	-1.0	-0.2	-0.3	0.8	-0.9	-0.4	-0.9	-0.1	-0.8	-1.5	-0.3
Lung FVC	0.5	2.6	4.5	1.7	2.1	2.1	1.8	1.8	-0.3	1.4	1.5	1.2	1.7	1.4	1.6	1.1	1.4	2.1	1.9
Hand grip strength (left)	0.5	1.3	9.9	0.4	-0.1	-0.1	-0.2	0.0	3.1	1.7	1.3	1.1	0.1	-0.5	1.1	0.2	0.2	1.6	0.3
Medication: Co-codamol	0.5	0.5	3.5	0.2	0.2	0.5	0.3	0.4	-1.4	-1.9	-0.4	-1.3	-0.1	-0.3	-0.4	-0.4	-0.3	0.4	-0.3
Body mass index (BMI)	0.5	2.2	4.6	0.7	-1.9	-1.6	-1.1	-2.1	0.6	-1.6	-1.0	-0.3	-1.8	-1.8	-1.6	-1.5	-1.7	-1.7	-1.3
Impedance of leg (left)	0.5	2.6	13.5	-1.8	0.1	-0.0	-1.0	1.3	-2.8	-2.0	-1.8	-3.7	0.2	0.2	-1.1	-1.4	-0.2	0.7	-1.6
Trunk fat-free mass	0.5	3.0	28.4	-0.4	-0.9	-0.8	0.2	-3.1	5.3	2.0	1.2	1.5	-0.5	-0.6	0.6	0.6	-0.3	-0.3	0.2
Noisy workplace	0.5	0.6	0.9	0.2	-0.9	-0.8	-0.9	-0.9	0.9	-0.3	-0.8	-0.6	-0.8	-0.9	-0.8	-0.6	-0.8	-0.9	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	4.2	-2.1	-0.0	0.2	-0.2	-0.1	-0.9	-0.8	-0.7	-1.0	-0.1	-0.1	-0.5	-0.5	0.0	-0.5	-0.6
Lung cancer (father)	0.5	0.6	2.2	-1.5	-0.6	-0.6	-0.4	-0.3	1.2	-1.4	-0.5	-1.4	-0.2	-0.5	-0.2	-0.6	-0.1	-0.3	-0.7
Trunk predicted mass	0.5	3.0	28.1	-0.5	-0.9	-0.8	0.2	-3.1	5.3	2.0	1.1	1.5	-0.5	-0.7	0.6	0.6	-0.4	-0.3	0.2
Number of full brothers	0.5	0.6	2.7	-0.7	-0.1	0.3	-0.0	-0.3	-0.4	0.0	-0.7	-1.6	-0.2	-0.5	-0.7	-1.2	-0.7	1.4	-0.8
Had major operations	0.5	0.6	3.5	1.9	0.4	0.5	0.5	-0.4	-1.5	1.3	-0.5	-0.2	0.1	0.6	-0.5	0.0	0.1	-0.6	0.2
Whole body fat-free mass	0.5	3.1	24.0	-0.6	-1.6	-1.4	-0.4	-3.6	4.9	1.3	0.4	1.1	-1.2	-1.3	-0.1	-0.1	-1.0	-1.0	-0.4
Mood swings	0.5	1.0	6.9	2.6	-0.4	-0.4	-0.1	-0.6	-2.3	-0.6	-0.5	-0.3	-0.3	-0.1	-0.9	-0.6	-0.5	-0.5	-0.5
Medication: Gliclazide	0.5	0.6	3.8	-0.5	-0.7	-0.5	-0.7	-1.1	1.9	-0.3	-0.4	-1.0	-0.5	-0.8	-0.2	-0.5	-0.4	0.2	-0.7
Average weekly champagne plus white wine intake	0.5	0.7	3.0	0.4	0.3	0.5	1.2	-0.7	1.7	0.9	0.8	1.3	0.1	-0.5	0.7	-0.4	-0.2	1.4	0.5
Illnesses of father: High blood pressure	0.5	0.6	3.6	0.3	-0.3	-0.1	-0.2	-0.2	-1.9	0.3	-0.6	-1.4	0.2	0.3	-0.6	-0.7	0.2	-1.3	-0.7
Arm fat-free mass (left)	0.5	2.3	18.7	-0.2	-1.2	-1.0	0.1	-3.2	4.3	1.1	0.5	0.8	-0.9	-1.1	-0.1	-0.1	-1.0	-0.4	-0.2
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.5	-1.5	-0.7	-0.7	-0.6	-1.6	-0.1	-0.0	-0.6	-0.1	-0.8	-0.8	-0.7	-0.6	-0.8	-0.3	-0.5
Arm predicted mass (left)	0.5	2.6	17.8	-0.2	-1.5	-1.3	-0.3	-3.5	4.2	1.0	0.3	0.6	-1.2	-1.4	-0.3	-0.4	-1.2	-0.5	-0.6
Alzheimer’s Disease (in mother)	0.4	0.5	1.9	1.2	1.0	0.8	0.4	0.6	-0.6	0.2	-0.0	0.3	0.6	0.5	0.5	-0.5	0.4	1.4	0.5
Alzheimer’s Disease (in father)	0.4	0.5	1.8	-1.2	-0.2	-0.0	0.1	-1.2	-0.1	-1.3	-0.4	-1.0	-0.2	-0.7	-0.3	-0.8	-0.5	0.4	-0.5
Alzheimer’s Disease (including proxy)	0.4	0.5	2.9	0.1	0.5	0.5	0.3	-0.4	-0.5	-0.4	-0.4	-1.3	0.4	-0.2	0.1	-1.4	-0.0	1.7	-0.4
Crohns Disease (2017)	0.4	0.9	4.4	-1.2	-0.4	-0.5	-0.7	0.8	-2.1	-1.7	-0.7	-0.8	-0.4	-0.6	-0.8	-0.9	0.0	-0.9	-1.0
Lung FEV1/FVC ratio	0.4	2.1	9.5	0.4	1.7	1.9	2.0	1.5	1.0	0.5	1.4	0.7	1.4	0.9	1.5	0.8	0.8	3.1	1.3
Relative age of first facial hair	0.4	0.9	6.7	2.6	0.3	0.3	0.1	2.2	-1.0	-0.8	-0.3	-0.8	0.4	0.2	-0.2	-0.4	0.3	0.0	-0.2
Ever had hysterectomy (womb removed)	0.4	0.5	1.2	-1.1	-0.1	-0.1	-0.1	-0.9	-1.0	-1.0	-0.7	-0.6	-0.5	-0.5	-0.9	-0.8	-0.8	0.1	-0.5
Impedance of leg (right)	0.4	1.9	8.4	-1.7	0.3	0.2	-0.9	1.7	-2.6	-1.8	-1.3	-2.9	0.4	0.4	-0.8	-0.9	0.2	0.6	-1.2
Hand grip strength (right)	0.4	1.0	6.2	0.5	-0.0	0.0	0.1	-0.1	2.5	2.2	0.9	0.9	0.0	-0.3	0.9	0.3	0.1	1.3	0.3
Current tobacco smoking	0.4	0.7	3.3	0.5	-0.7	-0.5	-0.8	-0.3	0.2	-1.3	-0.5	-1.8	-0.3	-0.8	-0.7	-1.2	-0.2	-0.3	-1.3
Maternal smoking around birth	0.4	0.6	1.3	-1.1	-0.9	-1.0	-0.7	-1.0	0.3	-0.9	-0.5	-0.4	-1.0	-0.9	-0.6	-0.4	-0.9	-1.0	-0.4
Relative age voice broke	0.4	0.6	1.7	1.1	0.8	0.7	1.0	1.3	-0.8	-0.3	0.8	0.8	0.5	0.6	0.5	0.7	0.4	0.6	0.9
Taking other prescription medications	0.4	0.6	1.4	0.1	-0.6	-0.6	-0.7	-1.1	-1.2	-0.4	-0.5	0.6	-1.1	-1.0	-1.1	-0.5	-1.1	-0.8	-0.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	3.9	0.1	0.4	0.2	0.3	-0.2	-2.0	0.3	-0.7	-0.1	-0.0	0.9	-0.9	0.4	-0.1	-1.3	0.2
Medication: Atenolol	0.4	0.5	7.5	2.7	0.0	0.0	0.1	0.1	0.0	0.3	-0.2	0.4	-0.0	0.2	-0.3	-0.3	-0.1	-0.3	-0.0
Past tobacco smoking	0.4	0.7	2.0	1.4	0.6	0.9	1.4	0.8	0.9	0.2	0.8	1.0	0.4	-0.3	0.7	0.1	0.2	1.2	0.6
Hair/balding pattern: Pattern 2	0.4	0.5	1.8	1.2	0.4	0.3	0.1	1.3	-1.1	-0.3	0.4	0.3	0.4	0.9	0.3	1.1	0.5	-0.1	0.6
Neuroticism score	0.4	0.9	6.8	2.6	0.5	0.3	0.8	0.7	-1.4	-0.1	0.4	0.7	0.7	1.1	0.1	0.6	0.7	-0.1	0.6
Birth weight of first child	0.4	0.8	7.5	-2.7	0.6	0.7	-0.2	0.6	1.2	0.4	-0.2	-1.1	0.5	0.5	0.4	0.1	0.4	0.8	-0.1
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.9	0.8	0.2	-0.0	0.7	-0.5	-1.2	-0.2	-0.1	0.2	0.3	0.9	-0.3	0.7	0.4	-1.7	0.2
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.7	1.2	-0.4	-0.6	-0.3	-0.8	-1.3	0.0	-0.3	0.2	-0.6	-0.3	-0.6	-0.0	-0.5	-1.0	-0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.5	0.0	-0.2	-0.6	-1.2	0.3	-1.0	-0.8	-1.2	-0.4	-0.5	-0.1	-0.9	-0.8	-0.3	-0.9	-0.6
Ever had bowel cancer screening	0.4	0.5	2.7	-1.0	-0.4	-0.3	-0.1	-0.5	-0.8	-1.0	-0.4	-1.6	-0.1	-0.2	-0.6	-0.6	-0.3	-0.1	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	3.0	-0.1	-0.2	-0.1	-0.2	-0.5	-1.7	-1.6	0.1	-1.1	0.3	0.0	-0.4	0.0	0.1	0.3	-0.5
Osteoporosis (self-reported)	0.4	0.5	3.0	0.2	-0.0	-0.1	-0.2	0.5	-1.6	-1.7	-0.4	-0.6	-0.3	0.1	-0.6	0.4	-0.3	-0.8	0.1
Smoking status: Current	0.4	0.6	2.6	0.5	-0.7	-0.4	-0.7	-0.5	0.5	-1.3	-0.2	-1.6	-0.2	-0.8	-0.5	-1.1	-0.2	0.1	-1.2
Ever smoked	0.4	0.6	2.5	-0.6	-0.6	-0.9	-1.6	-0.8	-1.0	-0.2	-0.7	-1.1	-0.4	0.2	-0.7	-0.2	-0.3	-1.2	-0.7
Basal cell carcinoma (self-reported)	0.4	0.5	1.3	0.7	0.8	0.7	1.1	-0.2	-0.1	-0.1	0.7	0.1	0.9	0.9	0.6	0.5	0.7	1.1	0.6
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.5	0.3	0.7	0.8	1.2	-0.2	0.0	0.7	0.9	0.4	0.8	0.8	0.5	0.8	0.4	1.2	0.9
Reaction Time	0.3	0.6	3.7	-1.9	0.5	0.6	-0.1	1.1	0.7	0.4	0.0	-0.3	0.7	0.5	0.2	0.1	1.2	-1.3	0.2
Lupus	0.3	0.5	2.3	-0.6	0.7	0.7	0.9	-0.1	-1.5	0.9	0.5	0.9	0.5	0.6	0.3	0.7	0.4	0.1	0.8
Blood Eosinophil Count	0.3	2.5	6.6	2.0	0.9	0.9	1.9	1.8	-0.6	2.4	2.1	2.6	1.1	1.4	1.0	1.8	1.1	-0.2	1.4
Heel T-Score	0.3	2.7	5.8	0.6	-2.1	-2.2	-1.5	-2.4	0.9	-0.8	-1.2	0.5	-2.4	-2.3	-1.2	-1.3	-2.2	-1.4	-1.1
BMI	0.3	1.8	4.9	0.7	-1.8	-1.4	-0.9	-2.2	2.0	-1.4	-0.6	-0.2	-1.1	-1.1	-1.1	-1.3	-1.0	-1.8	-1.1
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	2.0	0.7	-0.5	-0.5	-0.1	-0.4	0.8	0.9	0.1	0.6	-0.3	-0.1	-0.2	0.4	0.0	-1.4	0.1
Townsend deprivation index at recruitment	0.3	0.5	3.9	-0.9	0.4	0.5	-0.2	0.2	2.0	-0.4	0.4	-0.3	0.7	0.6	0.5	0.4	0.8	0.3	0.3
Age when periods started (menarche)	0.3	0.7	3.0	-1.1	-0.1	0.1	-0.3	-0.1	0.6	-1.7	-0.5	-1.3	-0.2	-0.6	-0.4	-0.9	-0.6	1.4	-0.5
Qualifications: CSEs or equivalent	0.3	0.4	1.2	-0.6	-0.4	-0.2	-0.2	-0.1	-0.8	0.3	-1.1	-1.0	-0.5	-0.2	-1.0	-0.9	-0.8	-0.5	-0.8
Sitting height	0.3	2.0	19.4	-0.4	-0.2	-0.3	0.2	-1.7	4.4	2.1	1.1	1.6	-0.1	-0.3	1.0	0.5	-0.1	0.4	0.5
Alcohol usually taken with meals	0.3	0.4	5.9	-0.1	-0.0	-0.1	-0.0	0.6	-2.4	-0.1	-0.1	-0.1	0.2	0.4	-0.3	-0.2	0.1	-0.2	-0.2
Mouth/teeth dental problems	0.3	0.5	2.5	-0.5	-0.9	-0.7	-0.9	0.5	1.6	-0.3	-0.1	0.2	-0.7	-0.9	0.1	-0.3	-0.3	-1.1	-0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	1.8	1.1	0.2	0.2	0.1	0.8	-0.0	1.4	-0.2	0.8	-0.4	-0.3	0.0	0.2	-0.1	-0.8	0.3
Time employed in main current job	0.3	0.3	1.8	1.2	0.3	0.2	-0.1	0.2	0.4	0.4	0.1	1.4	0.0	0.1	0.4	0.6	0.1	0.5	0.8
Father’s age at death	0.3	0.4	1.4	-1.1	0.2	0.2	0.4	0.3	1.2	0.7	0.8	-0.1	0.9	0.5	0.6	0.4	1.1	-0.5	0.3
Hair/balding pattern: Pattern 3	0.3	0.4	1.0	0.1	-0.7	-1.0	-0.7	-0.8	0.8	-0.4	-1.0	0.1	-0.7	-0.4	-0.4	-0.5	-0.6	-0.9	-0.4
Asthma	0.3	0.5	4.5	-2.1	-0.3	-0.2	-0.6	-0.5	0.3	-0.8	-0.2	-1.1	-0.1	-0.5	-0.2	-0.4	0.0	-0.2	-0.5
Length of working week for main job	0.3	0.3	1.8	0.7	-0.8	-0.9	-0.5	-0.3	-0.0	0.3	-0.1	0.6	-0.5	-0.2	-0.3	0.2	-0.2	-1.3	-0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.4	0.5	0.7	0.6	0.5	0.8	0.2	0.8	0.5	1.5	0.4	0.7	0.4	0.8	0.6	-0.5	0.8
Comparative body size at age 10	0.3	0.9	5.2	1.4	-0.1	-0.1	0.0	2.3	-2.2	-0.4	-0.1	0.7	-0.2	0.3	-0.3	0.4	0.0	-1.4	0.3
Medication: Seretide 50 evohaler	0.3	0.4	3.5	-1.9	0.2	0.4	0.3	-0.2	0.8	-0.4	0.3	-0.0	0.1	-0.5	0.3	-0.2	-0.0	0.9	0.1
Mean time to correctly identify matches	0.3	0.6	1.6	-1.2	0.8	0.9	0.2	0.7	0.7	1.0	0.3	0.2	0.8	0.6	0.4	0.5	1.3	-0.8	0.7
Family relationship satisfaction	0.3	0.3	0.9	-0.2	-0.7	-0.9	-0.9	-0.8	0.8	-0.5	-0.3	-0.8	-0.3	0.1	-0.1	0.3	-0.1	-0.7	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.4	-0.4	0.5	0.6	0.7	-0.6	-1.0	-0.0	-0.3	-0.9	0.3	-0.2	-0.2	-0.7	-0.0	1.2	-0.3
Loneliness, isolation	0.3	0.4	2.5	0.7	0.1	0.0	0.1	-0.6	-1.6	-1.0	0.0	-0.4	0.3	0.5	-0.3	0.3	0.4	-0.7	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	2.1	-1.2	0.6	0.6	0.7	-0.3	-1.1	-0.5	0.4	0.1	0.4	-0.2	0.3	-0.3	0.1	1.5	0.2
Back pain experienced in last month	0.3	0.5	2.2	-0.2	-0.7	-0.8	-0.2	-1.5	-1.3	-0.7	-0.0	-0.7	-0.4	-0.2	-0.6	-0.2	-0.5	-0.2	-0.6
Mineral and other dietary supplements	0.3	0.4	1.7	-1.1	0.6	0.6	0.2	0.4	0.3	0.4	0.2	1.3	0.1	0.3	0.5	0.7	0.4	-0.4	0.8
Supplements: Calcium	0.3	0.3	2.5	0.0	0.3	0.3	0.5	0.1	-1.6	-0.5	-0.4	-1.0	0.1	0.3	-0.6	-0.1	-0.3	0.1	-0.1
Heart disease (siblings)	0.3	0.3	1.9	-0.7	0.3	0.6	0.3	0.1	-0.7	-1.4	-0.2	-0.9	0.2	-0.2	-0.3	-0.5	0.1	0.5	-0.3
Alcohol drinker status: Previous	0.3	0.3	1.8	-1.3	-0.3	-0.2	-0.4	0.3	-0.7	-0.8	-0.5	-0.1	-0.6	-0.7	-0.4	-0.3	-0.7	0.1	-0.2
Worry (Nagel 2018)	0.2	0.5	2.3	0.7	-0.4	-0.5	-0.5	-0.7	-1.0	-0.3	-1.0	-1.5	-0.2	0.0	-0.8	-0.5	-0.2	-0.5	-0.7
Rheumatoid Arthritis	0.2	0.3	0.8	0.7	0.4	0.2	0.3	0.9	0.8	0.3	0.1	-0.4	0.6	0.5	0.8	0.2	0.9	-0.6	0.2
Respiratory disease	0.2	0.4	2.0	-1.4	-0.4	-0.3	-0.8	-0.5	0.5	-0.6	-0.4	-0.9	-0.2	-0.5	-0.3	-0.7	-0.1	-0.3	-0.6
Tanning	0.2	2.0	11.0	-0.5	-1.6	-1.5	-0.7	-2.6	3.3	-0.1	-0.4	-0.3	-1.1	-1.5	-0.2	-1.1	-0.9	-1.2	-1.2
Frequency of depressed mood in last 2 weeks	0.2	0.2	0.9	0.9	0.1	0.1	-0.1	0.2	-0.7	-0.8	-0.2	-0.7	0.4	0.4	-0.3	-0.4	0.3	-0.1	-0.3
Hearing difficulty/problems: Yes	0.2	0.3	1.6	-0.6	0.1	0.1	0.5	-1.1	-0.4	-0.2	-0.5	-0.3	-0.2	-0.5	-0.4	-1.3	-0.4	0.3	-0.3
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	2.4	-0.0	0.6	0.5	0.8	0.3	-1.6	-0.3	0.0	-0.0	0.2	0.5	-0.1	0.1	-0.1	0.3	0.4
Supplements: Zinc	0.2	0.2	1.5	1.2	-0.1	-0.0	-0.0	0.1	0.1	0.5	0.3	-0.5	0.5	0.2	0.3	-0.4	0.2	0.6	-0.3
Severe depression (siblings)	0.2	0.2	0.9	0.7	-0.0	0.2	0.7	0.3	0.5	-0.2	0.8	0.6	0.0	-0.5	0.3	-0.1	-0.1	0.9	0.1
Fed-up feelings	0.2	0.4	3.4	1.8	-0.4	-0.4	-0.1	0.1	-0.9	-0.9	0.1	0.3	-0.2	-0.1	-0.5	-0.1	-0.1	-0.8	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.3	0.7	-0.3	-0.3	-0.3	0.2	-0.8	-0.4	-0.4	-0.4	-0.2	0.2	-0.6	-0.1	-0.1	-1.2	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.6	3.7	0.4	0.4	0.1	0.3	0.2	0.8	1.1	0.7	1.9	-0.1	0.4	0.7	0.9	0.1	0.1	1.0
Supplements: Glucosamine	0.2	0.2	0.9	-0.4	0.4	0.4	0.6	-0.2	0.9	-0.5	0.6	0.2	0.2	0.2	0.4	0.5	-0.0	0.9	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	2.0	0.3	-0.2	-0.3	-0.3	-0.6	-0.8	-1.4	-0.2	-0.0	-0.3	-0.5	-0.5	-0.6	-0.3	0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	4.9	-0.1	-0.0	-0.3	-0.0	-0.3	0.1	1.1	0.2	2.2	-0.7	-0.2	0.1	0.3	-0.5	-0.4	0.6
Number of live births	0.2	0.3	1.6	-0.7	0.9	1.1	0.7	0.1	-0.3	0.1	0.1	0.0	0.2	0.0	0.1	-0.1	0.0	1.3	0.4
Breastfed as a baby	0.2	0.2	1.4	-0.3	-0.3	-0.1	-0.2	-0.0	-0.2	0.3	-0.8	-1.2	-0.0	0.0	-0.5	-0.6	-0.2	-0.2	-0.7
Peak expiratory flow (PEF)	0.2	0.6	2.4	-0.8	-0.6	-0.5	-0.1	-1.5	0.6	-0.1	-0.4	-0.8	-0.7	-0.9	-0.7	-0.8	-1.0	0.2	-0.8
Birth weight	0.2	0.4	2.8	-1.7	-0.3	-0.1	-0.4	0.2	-1.4	-0.0	-0.2	-0.9	0.0	0.2	-0.3	-0.3	0.1	-0.3	-0.4
Heart disease (mother)	0.2	0.3	1.4	0.7	0.1	0.0	-0.0	0.3	-0.8	0.4	-0.3	-0.9	0.4	0.1	-0.1	-0.6	0.0	1.2	-0.4
Average weekly red wine intake	0.2	0.3	1.1	0.9	0.2	0.1	0.2	-0.1	0.4	0.9	0.6	1.1	-0.0	-0.1	0.6	0.6	-0.1	0.9	0.6
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.8	-0.2	0.7	0.5	0.0	-0.1	0.9	-0.1	0.1	-0.3	0.7	0.8	0.7	0.2	0.6	0.6	0.3
Qualifications: nursing, teaching	0.2	0.3	2.0	-1.4	-0.1	-0.1	0.1	-0.9	-0.9	0.4	0.1	0.1	-0.1	-0.4	-0.2	-0.5	-0.3	0.5	-0.3
Breast cancer (self-reported)	0.2	0.2	0.6	0.6	0.5	0.4	0.2	-0.3	-0.2	0.8	0.4	-0.1	0.5	0.4	0.4	0.3	0.5	0.8	0.4
Asthma (self-reported)	0.2	0.4	3.1	-1.8	-0.3	-0.2	-0.6	-0.1	0.0	-0.8	-0.1	-1.1	-0.0	-0.3	-0.2	-0.2	0.1	-0.5	-0.4
Guilty feelings	0.2	0.3	1.7	0.7	-0.5	-0.5	-0.2	-0.5	-0.4	-1.3	-0.1	-0.1	-0.3	0.1	-0.4	0.7	-0.3	-1.1	-0.0
Ever taken oral contraceptive pill	0.2	0.2	1.0	-0.9	-0.0	-0.3	0.1	-0.3	0.5	1.0	0.5	0.6	-0.3	0.0	0.1	0.7	-0.3	-0.0	0.4
Ever depressed for a whole week	0.2	0.2	1.0	0.7	0.5	0.3	0.5	0.4	-0.4	-1.0	0.1	-0.3	0.4	0.6	0.4	0.6	0.3	0.2	0.5
Commuting to job workplace: Cycle	0.2	0.2	0.8	0.5	-0.2	-0.1	-0.2	0.9	-0.2	0.8	0.6	0.4	0.1	0.4	0.2	0.8	0.2	-0.3	0.1
Mean Putamen Volume	0.1	0.2	0.8	0.1	0.2	0.0	0.1	0.9	0.2	-0.1	0.5	0.9	0.2	0.2	0.5	0.3	0.3	0.3	0.5
Hair Pigment	0.1	2.1	21.3	1.9	0.7	0.8	1.6	0.6	-4.6	-1.1	0.9	0.7	0.3	0.4	-0.9	0.5	0.0	0.8	0.4
Nervous feelings	0.1	0.2	0.7	0.4	0.2	0.0	0.2	-0.3	-0.6	0.3	-0.1	0.1	0.4	0.8	0.1	0.5	0.6	-0.8	0.3
Forced vital capacity (FVC)	0.1	0.3	1.1	-0.4	-0.7	-0.6	-0.5	-0.8	1.1	0.1	-0.1	-0.2	-0.6	-0.6	-0.4	-0.5	-0.7	0.1	-0.5
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	1.4	0.1	-0.1	-0.1	0.2	-0.6	0.9	0.3	0.2	-0.1	-0.2	-0.4	-0.1	-0.4	-0.6	1.2	-0.2
Depression (self-reported)	0.1	0.1	0.4	-0.1	0.3	0.3	-0.1	-0.2	-0.5	0.0	-0.7	-0.3	-0.4	-0.4	-0.4	-0.2	-0.5	0.4	-0.2
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.6	-0.8	0.1	-0.0	0.1	0.2	-0.2	-0.3	0.6	0.5	0.0	-0.2	0.3	0.1	0.2	0.3	0.2
Forced vital capacity (FVC), Best measure	0.1	0.3	0.7	-0.6	-0.7	-0.7	-0.6	-0.9	0.8	0.4	-0.0	-0.0	-0.4	-0.4	-0.3	-0.5	-0.4	-0.2	-0.5
Exposure to tobacco smoke outside home	0.1	0.2	1.1	0.3	0.3	0.2	0.4	0.4	-1.0	0.5	-0.1	-0.2	0.5	0.7	0.0	-0.1	0.2	0.3	0.1
Chest pain or discomfort	0.1	0.2	0.8	0.9	-0.0	0.2	0.5	0.5	-0.5	-0.7	0.3	0.3	-0.0	-0.2	-0.2	-0.1	-0.0	0.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	2.0	-1.4	-0.3	-0.1	-0.4	-0.4	0.8	-0.2	0.3	-1.2	0.3	0.2	0.1	0.2	0.3	0.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	1.1	0.6	-0.2	-0.1	0.1	-0.2	-1.0	-0.2	-0.1	-0.8	0.0	-0.1	-0.4	-0.2	-0.0	-0.3	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.5	-0.0	-0.2	-0.2	0.0	-0.4	0.7	0.6	0.2	0.1	-0.1	-0.2	0.0	-0.3	-0.3	0.5	-0.2
Wheeze or whistling in the chest in last year	0.0	0.1	0.8	-0.3	0.1	0.2	0.2	-0.1	0.1	-0.1	0.1	-0.4	0.2	0.0	-0.0	0.3	0.2	-0.9	0.3

Hub : Genes

CGREF1

Models

Trait associations