Best TWAS P=2.75e-09 · Best GWAS P=4.52e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PHACTR1 | 0.19 | 0.09 | enet | 25 | 0.12 | 5.7e-07 | -5.9 | 5.8 | 5.7e-09 | -0.86 | 0 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | RP1-257A7.5 | 0.11 | 0.14 | lasso | 3 | 0.13 | 1.7e-07 | -5.9 | 5.9 | 2.7e-09 | -0.95 | 0 | 1.00 | TRUE |
| 3 | GTEx | Artery Coronary | RP1-257A7.5 | 0.25 | 0.07 | lasso | 5 | 0.09 | 5.5e-04 | 4.2 | 5.4 | 5.7e-08 | -0.88 | 0 | 0.99 | FALSE |