Best TWAS P=7.01e-14 · Best GWAS P=4.77e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | LRP1 | 0.15 | 0.12 | lasso | 2 | 0.10 | 3.9e-08 | -7.5 | 7.5 | 7.0e-14 | -1.00 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Artery Tibial | STAT6 | 0.08 | 0.03 | enet | 4 | 0.02 | 1.3e-02 | -6.5 | -6.7 | 1.8e-11 | 0.61 | 0.22 | 0.29 | TRUE |
| 3 | METSIM | Adipose | NXPH4 | 0.04 | 0.01 | bslmm | 354 | 0.02 | 1.7e-04 | -6.4 | 5.6 | 1.6e-08 | -0.47 | 0.03 | 0.65 | FALSE |
| 4 | METSIM | Adipose | STAT6 | 0.08 | 0.02 | blup | 343 | 0.03 | 5.0e-06 | -6.5 | 5.7 | 1.2e-08 | -0.53 | 0.34 | 0.64 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | STAT6 | 0.04 | 0.01 | blup | 47 | 0.01 | 2.3e-02 | -6.4 | -7.3 | 2.1e-13 | 0.79 | 0.02 | 0.82 | FALSE |