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chr12:56,805,309-58,303,535
Best TWAS P=7.01e-14 · Best GWAS P=4.77e-14 conditioned to 1
56.8M
57M
57.2M
57.4M
57.6M
57.8M
58M
58.2M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Tibial
LRP1
0.15
0.12
lasso
2
0.10
3.9e-08
-7.5
7.5
7.0e-14
-1.00
0.00
1.00
TRUE
2
GTEx
Artery Tibial
STAT6
0.08
0.03
enet
4
0.02
1.3e-02
-6.5
-6.7
1.8e-11
0.61
0.22
0.29
TRUE
5
The Cancer Genome Atlas
Thyroid Carcinoma
STAT6
0.04
0.01
blup
47
0.01
2.3e-02
-6.4
-7.3
2.1e-13
0.79
0.02
0.82
FALSE
4
METSIM
Adipose
STAT6
0.08
0.02
blup
343
0.03
5.0e-06
-6.5
5.7
1.2e-08
-0.53
0.34
0.64
FALSE
3
METSIM
Adipose
NXPH4
0.04
0.01
bslmm
354
0.02
1.7e-04
-6.4
5.6
1.6e-08
-0.47
0.03
0.65
FALSE