Best TWAS P=1.2e-18 · Best GWAS P=2.13e-18 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | STAT6 | 0.11 | 0.08 | lasso | 3 | 0.11 | 9.1e-14 | -4.0 | -5.4 | 8.7e-08 | 0.52 | 0.98 | 0.02 | FALSE |
| 2 | GTEx | Artery Tibial | LRP1 | 0.15 | 0.12 | lasso | 2 | 0.10 | 3.9e-08 | -8.8 | 8.8 | 1.2e-18 | -1.00 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | STAT6 | 0.04 | 0.01 | blup | 47 | 0.01 | 2.3e-02 | -6.7 | -6.4 | 1.8e-10 | 0.79 | 0.02 | 0.73 | FALSE |