Hub : Genes

STAT6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1120	0.0390	4.8e-05	0.083	0.046	0.112	0.089	0.114	2.4e-10	2.6e-06	1.9e-13	5.2e-11	9.1e-14
2	GTEx	Artery Aorta	0.1240	0.0530	2.5e-03	0.071	NA	0.048	NA	0.038	9.0e-05	NA	1.1e-03	NA	3.8e-03
3	GTEx	Artery Tibial	0.0806	0.0382	9.5e-03	0.028	NA	0.018	NA	0.011	2.8e-03	NA	1.3e-02	NA	4.4e-02
4	GTEx	Brain Cerebellum	0.3630	0.1190	1.9e-03	0.138	NA	0.046	NA	0.131	7.2e-05	NA	1.7e-02	NA	1.1e-04
5	GTEx	Colon Sigmoid	0.2200	0.0950	4.9e-03	0.095	NA	0.080	NA	0.124	3.1e-04	NA	9.1e-04	NA	3.8e-05
6	METSIM	Adipose	0.0751	0.0241	1.8e-06	0.018	0.035	0.022	0.033	0.022	7.8e-04	5.0e-06	2.3e-04	7.9e-06	2.2e-04
7	NTR	Blood	0.3698	0.0383	0.0e+00	0.241	0.281	0.303	0.276	0.294	8.9e-77	2.3e-91	8.0e-100	2.2e-89	3.9e-96
8	YFS	Blood	0.7382	0.0223	0.0e+00	0.576	0.660	0.734	0.530	0.727	2.1e-237	9.5e-298	0.0e+00	2.3e-209	0.0e+00
9	TCGA	Thyroid Carcinoma	0.0360	0.0200	4.5e-03	0.009	0.012	0.010	NA	0.009	4.1e-02	2.3e-02	3.6e-02	NA	3.8e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	2.2	3.5	9.2	2.6	0.9	1.5	-1.5	3.0	-1.7	1.9	-1.4	1.5
Bipolar Disorder or Schizophrenia	5.7	13.9	21.1	4.5	1.6	3.9	-0.3	4.5	-4.1	3.9	-3.7	4.6
Depressed Affect (Nagel 2018)	2.8	5.9	15.0	-2.8	-0.3	-3.3	-1.6	-0.7	3.9	-1.2	1.6	-3.5
Depression (Nagel 2018)	1.3	1.9	5.2	-1.8	0.5	-0.8	-2.0	1.0	2.3	1.1	-0.7	-1.3
Intelligence (Savage-Jansen 2018)	3.0	9.3	16.2	-1.5	-0.5	-3.5	-0.4	-3.5	4.0	-3.6	4.0	-3.4
Neuroticism (Nagel 2018)	0.9	2.1	7.1	-1.4	-0.6	-2.1	-0.1	0.2	2.7	-0.4	0.7	-2.1
Schizophrenia (2018)	5.6	11.7	22.3	3.7	1.3	3.8	0.7	3.3	-3.9	3.5	-3.7	4.7
Schizophrenia vs Biploar Disorder	0.4	0.5	1.4	0.5	-0.7	0.7	0.1	-0.2	-0.6	0.3	-1.1	1.2
Worry (Nagel 2018)	0.2	0.5	2.4	-0.6	0.1	0.2	1.5	0.8	0.5	0.5	-0.8	0.1
Alzheimer’s Disease (in mother)	1.6	1.8	4.8	-0.9	0.8	0.6	-1.2	2.1	-0.5	1.9	-2.2	0.4
Alzheimer’s Disease (in father)	0.8	0.9	4.0	1.2	-1.2	0.3	-2.0	0.5	-1.0	0.1	-0.3	0.3
Alzheimer’s Disease (including proxy)	1.4	2.1	5.2	0.0	0.2	0.9	-2.3	1.9	-0.7	1.9	-2.2	0.3
Crohns Disease (2017)	2.2	4.9	9.1	-0.6	-0.1	-2.2	0.2	-3.0	2.6	-2.8	2.9	-2.6
Irritable Bowel Disease (IBD)	1.0	2.3	5.5	0.1	-0.5	-1.2	0.3	-2.3	2.1	-1.6	2.0	-1.6
Ulcerative Colitis (UC)	0.1	0.2	0.9	0.9	-0.1	0.0	0.3	-0.7	0.8	-0.1	0.4	-0.1
Major Depression (MDD)	0.9	1.1	4.6	0.5	-0.7	-0.8	-0.4	-0.8	2.1	-0.9	0.8	-1.1
Reaction Time	0.5	0.9	3.2	0.6	0.8	0.0	-1.8	1.4	1.2	0.7	0.0	-0.1
Verbal and Numeric Reasoning (VNR)	2.0	4.8	9.1	-0.9	-1.7	-2.6	-0.1	-2.2	2.0	-2.6	3.0	-2.8
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	0.3	0.4	1.9	0.3	1.4	-0.6	-0.9	0.0	0.4	0.1	0.1	-0.7
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.8	1.2	4.0	2.0	-0.4	0.2	1.9	-0.1	-1.0	-0.6	0.4	1.2
Bipolar Disorder (2011)	1.9	1.8	4.8	1.7	-0.2	1.2	-0.4	2.2	-1.9	1.3	-1.4	0.0
Body Mass Index (BMI) (2010)	0.2	0.3	1.4	-0.3	0.1	-0.2	-0.7	-0.6	1.2	-0.0	0.0	0.4
Coronary Artery Disease (CAD)	0.4	0.5	2.2	1.5	0.2	0.3	0.1	0.9	-0.5	0.6	-0.4	0.6
Crohns Disease (2012)	3.7	6.0	9.8	-2.0	-1.4	-2.7	-1.3	-2.7	2.5	-2.9	2.9	-3.1
Mean Putamen Volume	1.4	1.6	5.0	-1.4	-0.4	-2.2	-0.1	-1.1	1.3	-1.1	1.1	-1.5
Fasting Glucose	2.4	2.9	5.6	0.4	-0.9	-2.0	-0.1	-2.2	2.4	-2.1	2.0	-1.3
HbA1C	0.4	0.4	1.6	-0.3	-0.8	0.2	-0.2	-1.3	0.8	-0.5	0.3	0.2
HDL Cholesterol	0.4	0.6	1.7	0.8	0.3	0.7	1.3	-0.7	-1.3	-0.3	-0.1	0.5
LDL Cholesterol	0.8	1.2	7.6	0.7	0.4	-0.2	2.8	0.9	-0.2	0.8	-0.5	1.0
Lupus	2.5	3.8	7.9	0.0	-0.1	-2.1	2.5	-2.8	1.4	-2.5	2.6	-0.7
Neuroticism (2016)	2.3	3.3	5.6	-1.2	-1.7	-2.0	-0.4	-1.5	2.4	-2.2	2.2	-1.8
Primary Biliary Cirrhosis	3.3	4.7	13.0	-1.9	-1.4	-2.8	-1.9	-0.9	2.9	-1.0	1.2	-3.6
Rheumatoid Arthritis	1.3	1.8	3.6	-1.0	1.4	1.3	-1.8	0.5	-0.0	1.8	-1.9	1.0
Schizophrenia (2014)	5.0	11.0	17.7	3.7	0.9	3.5	0.1	3.8	-3.5	3.5	-3.9	4.2
Triglycerides	0.4	0.7	2.9	1.4	0.2	-0.4	-0.9	0.5	1.7	-0.1	0.4	0.0
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.3	0.8	-0.8	0.1	0.5	1.1	-0.1	0.7	-0.6	0.1
Ulcerative Colitis	0.1	0.2	0.6	0.8	0.0	0.3	-0.4	-0.6	0.6	0.1	0.2	0.0
Blood Eosinophil Count	1.5	11.8	50.7	-0.1	4.7	4.3	1.6	-1.3	-2.9	1.5	-0.7	7.1
Blood Platelet Count	1.2	14.4	51.6	-1.3	5.9	-1.9	-7.2	4.6	0.2	-0.1	1.6	-3.6
Blood Red Count	0.1	0.9	1.9	-1.4	-0.4	-1.4	-0.8	0.1	1.0	0.9	-0.9	-0.6
Blood White Count	0.4	2.8	7.8	-0.4	1.9	2.3	-0.9	1.6	-0.6	1.8	-1.2	2.8
Heel T-Score	0.8	6.4	24.1	-2.8	3.1	0.4	-4.9	2.4	-1.2	1.9	-1.1	-1.8
BMI	0.6	3.7	11.3	2.8	0.6	2.2	-0.3	-0.7	-2.9	-0.0	0.3	3.4
Height	2.3	44.0	82.3	-3.1	-4.6	-8.4	1.8	-7.9	9.1	-7.0	6.1	-7.8
Waist Hip Ratio (WHR)	0.2	1.1	4.2	0.2	-1.5	2.1	0.6	-1.0	-1.0	-0.7	-0.2	0.4
Systolic Blood Pressure	0.9	4.7	14.7	0.8	1.8	2.2	-1.4	3.8	-2.3	2.1	-1.8	2.0
Smoking Status	1.6	3.8	7.4	-1.1	-2.2	-2.1	-1.3	-1.1	1.9	-2.2	2.4	-2.7
Allergy or Eczema	6.2	16.2	46.8	-1.9	6.8	5.0	1.5	-0.9	-3.1	2.3	-2.5	6.8
Cardiovascular Disease	0.3	0.9	3.1	-0.4	1.6	-0.1	-0.8	1.8	-1.2	0.2	-0.1	0.2
Hypothyroidism (self reported)	0.7	1.7	8.2	-0.8	2.9	-0.2	-0.6	-0.0	1.8	1.2	-1.3	0.3
Respiratory disease	13.1	29.3	80.6	1.2	6.6	8.3	1.1	0.7	-4.2	4.5	-5.4	9.0
Type 2 Diabetes (T2D) (2018)	0.6	1.1	7.1	0.4	-0.9	0.7	-2.7	-0.1	-0.7	-0.2	0.2	0.6
Lung FEV1/FVC ratio	4.5	23.0	52.4	7.2	2.6	6.3	1.7	2.3	-6.2	1.8	-2.2	7.2
Lung FVC	1.0	5.2	13.8	0.5	-2.7	-1.3	3.7	-1.9	1.5	-2.3	2.5	-2.4
Neuroticism	2.6	6.2	13.8	-2.4	-1.5	-3.6	0.7	-1.2	3.7	-2.1	2.2	-3.0
Chronotype (morning person)	0.7	1.6	5.6	-1.0	0.7	-0.6	0.1	-1.8	-0.2	-1.8	2.4	-0.7
Hair Pigment	0.2	5.5	12.2	1.5	3.5	2.4	0.6	1.5	-2.0	2.6	-2.7	2.8
Tanning	0.1	1.3	4.9	-0.4	-1.7	-1.2	1.0	0.4	-0.4	-0.6	0.3	-2.2
Hand grip strength (left)	1.0	2.7	6.9	-1.0	-2.2	-2.6	1.3	-1.2	0.9	-1.4	1.5	-1.9
Number of treatments/medications taken	3.0	5.5	15.8	-3.1	-0.9	-2.6	-3.0	-0.2	2.3	-0.6	1.1	-4.0
Average weekly spirits intake	1.1	1.3	4.7	-1.4	2.2	-0.2	0.7	1.9	0.3	0.9	-0.6	-0.1
Sensitivity / hurt feelings	2.2	3.7	10.9	-1.6	-2.5	-2.5	0.1	-0.1	3.3	-0.1	0.3	-2.6
Frequency of depressed mood in last 2 weeks	2.1	2.9	8.4	-2.5	1.4	-0.4	-1.7	0.8	2.9	1.5	-1.3	-1.5
Hearing difficulty/problems: Yes	0.6	1.0	2.4	-0.5	-0.7	-0.9	0.6	-1.5	0.4	-1.4	1.2	-0.8
Relative age of first facial hair	1.3	2.6	9.4	0.6	-0.3	0.8	3.1	-1.1	-1.9	-2.0	1.6	1.3
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.9	-1.7	0.6	-0.2	-1.2	-0.9	0.8	0.2	-0.2	-1.2
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.1	0.2	-1.0	0.9	-0.2	-0.3	-0.6	-0.0	-0.4	-0.3
Ever had hysterectomy (womb removed)	0.3	0.3	1.0	-0.7	-0.2	-0.0	-0.6	-0.5	-0.3	-0.7	0.6	-1.0
Systolic blood pressure, automated reading	1.4	4.1	10.0	1.7	1.1	2.4	-1.4	3.2	-1.6	2.1	-1.9	2.1
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.7	0.3	1.0	1.1	-1.6	0.6	-1.1	0.5	-0.7	1.1
Angina	0.4	0.5	1.4	-0.5	-0.7	-0.4	-1.2	0.1	-0.5	-0.8	1.1	-0.1
Medication for hormone replacement therapy	0.7	0.8	2.8	-1.6	0.1	-0.3	-0.7	0.3	0.7	0.3	-0.2	-1.7
Vitamin and mineral supplements	9.6	13.1	41.1	4.2	2.7	4.4	2.6	1.9	-3.3	2.4	-2.5	6.4
Supplements: Zinc	4.3	4.7	8.4	-1.0	-1.8	-2.7	-1.2	-2.7	2.9	-1.8	1.7	-2.8
Medication: Co-codamol	0.1	0.2	0.5	0.2	0.7	0.3	-0.7	0.0	-0.2	0.5	0.0	-0.3
Medication: Metformin	0.3	0.4	1.7	0.4	0.9	0.4	-1.3	-0.2	-0.6	-0.5	0.5	0.1
Diabetes (father)	0.2	0.3	1.2	1.1	-0.6	-0.2	-0.1	0.8	0.0	0.6	-0.1	-0.1
Diabetes (mother)	3.1	3.9	8.2	0.4	-0.8	-1.8	1.9	-2.5	2.1	-2.7	2.9	-1.3
Severe depression (siblings)	1.5	1.7	3.6	-0.8	1.9	1.5	0.3	1.4	0.9	1.2	-1.6	1.6
Pack years adult smoking proportion	0.8	1.2	3.5	0.5	1.9	1.2	0.9	0.8	-0.5	1.1	-1.0	1.3
Impedance of leg (right)	0.5	2.6	7.1	2.2	-0.7	1.8	2.7	1.2	-0.5	0.4	-1.0	2.3
Leg fat-free mass (left)	1.5	8.2	14.7	-1.5	-1.1	-3.8	-0.7	-3.8	3.3	-3.0	3.1	-3.2
Trunk fat percentage	0.8	3.4	9.1	3.0	0.6	2.4	0.8	0.1	-2.2	0.6	-0.7	2.9
Hand grip strength (right)	3.1	8.5	17.3	-3.3	-2.7	-4.2	1.3	-2.4	2.4	-2.4	2.4	-4.1
Townsend deprivation index at recruitment	1.2	1.7	3.3	-1.6	0.4	-0.9	0.1	-1.8	1.5	-1.8	1.8	-0.7
Current tobacco smoking	0.5	0.8	2.1	-0.8	-0.7	-0.8	-1.5	0.6	1.0	-0.2	0.3	-1.4
Average weekly fortified wine intake	0.6	0.7	2.6	0.5	0.1	1.6	0.2	0.5	-1.5	0.5	-0.3	0.8
Maternal smoking around birth	0.8	1.1	2.8	0.9	-0.9	-0.6	0.6	-1.5	0.0	-1.7	1.6	0.2
Fed-up feelings	2.4	4.4	12.7	-2.3	-0.4	-2.4	-1.5	-1.7	3.6	-1.5	1.9	-2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	3.9	-1.3	1.1	0.6	-1.1	1.5	0.9	2.0	-1.9	-0.3
Relative age voice broke	1.3	1.9	7.3	-0.7	-0.8	-0.6	2.7	-1.9	0.6	-1.7	1.3	0.2
Taking other prescription medications	0.2	0.4	1.5	-1.1	0.3	0.2	-1.2	-0.2	-0.5	0.1	-0.3	0.3
Age when periods started (menarche)	1.5	3.7	9.2	-1.1	-2.1	-1.8	3.0	-2.3	0.9	-2.2	2.0	-0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.8	-0.3	0.3	-0.3	0.7	-0.9	0.5	-0.7	0.8	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	3.6	-1.8	0.4	-1.1	-1.9	0.1	-0.1	0.1	-0.2	-1.3
Tinnitus: Yes, but not now, but have in the past	3.6	3.9	9.0	-3.0	-0.5	-2.5	0.8	-1.4	2.4	-1.6	1.6	-2.3
Qualifications: CSEs or equivalent	1.3	1.8	4.3	-0.8	-0.2	1.1	-1.9	1.4	0.0	2.0	-2.1	0.5
Serious illness, injury or assault to yourself	0.8	0.9	4.7	-1.6	0.6	0.0	-2.2	0.0	-0.0	0.5	-0.7	-0.5
High blood pressure	0.2	0.5	2.6	-0.8	1.6	-0.3	-0.1	0.7	-0.5	-0.1	0.3	0.1
Hayfever, allergic rhinitis or eczema	5.9	12.9	37.5	-1.5	5.8	4.6	1.3	-0.6	-2.8	2.4	-2.5	6.1
Multivitamins +/- minerals	4.4	5.5	18.2	-2.6	-0.7	-2.7	-2.9	-1.0	2.4	-0.8	1.2	-4.3
Stomach or abdominal pain in last month	2.0	2.4	13.0	-3.6	1.6	-1.1	-1.1	0.1	1.4	0.4	-0.3	-1.4
Supplements: Glucosamine	0.9	1.2	3.1	-1.8	-1.5	-1.1	0.0	-0.5	0.8	-0.1	0.5	-1.7
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	3.1	-1.8	0.4	-0.6	-0.5	-0.7	1.6	-0.3	0.3	-1.7
Medication: Atenolol	0.3	0.4	1.0	-0.3	1.0	-0.5	-0.2	0.7	-0.8	-0.5	0.9	0.0
Medication: Levothyroxine sodium	0.9	1.5	4.5	-2.0	2.1	-0.3	-0.1	0.1	1.2	1.1	-1.4	-0.4
Sitting height	3.5	25.1	68.7	-4.5	-2.6	-7.0	-1.4	-3.7	8.3	-3.1	2.8	-7.0
Chronic bronchitis/emphysema (father)	0.3	0.4	2.8	-0.2	-1.7	0.3	-0.4	0.3	-0.7	0.2	-0.1	-0.2
High blood pressure (mother)	0.3	0.5	1.1	0.2	0.2	-0.5	-0.4	-0.6	1.1	-0.8	1.0	-0.7
Body mass index (BMI)	0.4	1.6	4.3	2.1	0.5	1.1	-0.7	-0.5	-2.1	0.0	0.4	1.8
Impedance of leg (left)	0.5	2.7	6.6	2.1	-1.0	1.7	2.6	1.4	-1.1	0.5	-1.1	2.1
Leg predicted mass (left)	1.6	8.4	15.2	-1.6	-1.2	-3.9	-0.8	-3.8	3.4	-3.0	3.1	-3.3
Trunk fat mass	0.2	1.0	4.0	2.0	-0.1	0.7	0.5	-0.9	-0.9	-0.5	0.4	1.4
Waist circumference	0.2	0.8	1.8	1.3	-0.1	0.4	-0.6	-1.2	-1.4	-0.8	0.6	0.7
Number of incorrect matches in round	1.4	2.3	6.7	0.5	-1.6	1.5	-0.1	1.5	-0.9	2.0	-2.6	1.4
Past tobacco smoking	1.7	3.1	6.3	0.5	2.0	1.8	0.5	1.1	-0.4	2.4	-2.5	2.5
Alcohol usually taken with meals	0.8	1.3	4.3	-2.1	-0.7	-1.3	-1.0	0.7	0.4	0.2	-0.2	-1.9
Nervous feelings	0.2	0.3	2.0	-0.3	-0.2	-0.1	1.4	0.3	0.5	0.0	0.0	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	5.3	-2.3	1.4	0.5	-0.3	0.2	1.1	0.8	-0.8	-0.8
Hearing difficulty/problems with background noise	3.9	6.2	11.2	-2.2	-3.3	-2.7	-1.7	-1.9	2.1	-2.3	2.4	-3.3
Hair/balding pattern: Pattern 2	0.8	1.1	3.0	0.2	0.1	-1.7	0.6	-0.7	1.3	-0.7	0.9	-1.7
Had menopause	1.3	1.6	5.4	2.3	-1.5	1.7	-0.5	1.0	-1.3	0.7	-0.6	0.7
Had other major operations	1.4	1.7	3.2	0.9	1.1	1.8	-1.4	1.5	-0.3	1.6	-1.7	0.7
Forced vital capacity (FVC)	2.3	8.9	13.7	-1.1	-2.8	-3.2	2.9	-3.4	3.7	-3.3	2.6	-3.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	3.8	-1.1	1.9	0.6	-0.7	1.0	-1.8	1.1	-1.3	0.7
Ever unenthusiastic/disinterested for a whole week	2.4	2.9	6.7	-2.6	-0.8	-2.5	0.5	-0.2	2.2	-0.8	1.5	-2.1
Qualifications: None of the above	0.5	1.2	3.1	1.3	-0.2	0.6	-0.9	1.3	-1.8	0.4	-0.0	1.6
Financial difficulties in last 2 years	0.9	1.3	2.9	-0.7	-0.4	1.2	-1.5	1.1	-0.6	1.6	-1.7	-0.2
Mouth/teeth dental problems	0.4	0.6	2.1	0.9	-0.4	-0.7	1.5	-0.4	1.1	0.1	-0.1	-0.1
Heart attack	0.6	0.8	4.9	-2.2	0.8	0.2	-1.2	0.3	-0.1	0.0	-0.1	-0.0
Allergy	9.3	21.3	58.7	0.7	-6.9	-6.5	-1.6	0.2	3.3	-3.6	3.9	-7.7
Pain all over the body in last month	1.7	1.8	3.1	0.4	1.5	1.5	-1.0	1.2	-1.7	1.3	-1.2	1.8
Diabetes (self-reported)	0.2	0.4	1.3	0.4	0.6	0.7	-1.1	-0.1	-0.8	-0.1	0.3	0.8
Hayfever/allergic rhinitis (self-reported)	4.2	5.6	19.6	1.4	2.6	3.8	0.7	-0.6	-2.0	1.3	-1.2	4.4
Medication: Ramipril	0.4	0.5	2.9	-0.8	-0.5	-0.5	-1.7	0.2	-0.5	-0.0	-0.2	-0.7
Medication: Simvastatin	0.2	0.3	0.8	0.4	0.9	0.2	-0.7	0.9	-0.8	-0.1	0.4	-0.0
Fluid intelligence score	3.5	7.3	11.4	-1.8	-1.8	-3.4	0.5	-3.2	3.1	-3.0	3.1	-3.1
Illnesses of siblings	0.9	1.3	3.5	0.8	0.2	0.8	0.9	0.9	-1.6	1.2	-1.0	1.9
Neuroticism score	1.2	2.5	9.3	-1.6	-0.7	-2.0	0.6	-0.6	3.0	-1.0	1.1	-1.8
Weight	0.5	2.4	6.2	0.3	-1.2	-1.9	-0.3	-2.5	0.9	-2.1	2.1	-1.1
Impedance of arm (right)	0.4	2.0	6.2	0.5	0.3	2.5	1.6	0.6	-0.2	0.9	-1.7	2.2
Arm fat percentage (right)	0.7	2.7	8.5	2.1	1.0	2.2	0.4	-0.4	-2.4	0.3	-0.1	2.9
Trunk fat-free mass	3.1	17.5	37.3	-2.9	-2.9	-6.1	-1.1	-4.0	4.9	-4.0	4.1	-5.4
Hip circumference	0.1	0.6	1.3	0.8	-0.2	-1.1	-0.6	-1.1	-0.6	-0.9	1.1	-0.1
Time employed in main current job	2.5	2.9	5.3	1.3	1.4	2.1	0.5	1.3	-2.0	2.0	-2.3	1.8
Alcohol intake versus 10 years previously	1.9	2.8	5.7	-0.7	-1.3	-1.9	-0.6	-1.8	1.3	-2.0	2.4	-2.2
Father’s age at death	4.1	5.5	8.5	0.2	-2.8	-2.3	1.7	-2.9	2.9	-2.3	2.4	-2.4
Worrier / anxious feelings	2.3	4.3	8.0	-2.4	-1.9	-2.6	1.0	-1.8	2.4	-1.7	1.5	-2.8
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	7.6	-2.4	0.8	-1.2	-0.9	-1.3	2.8	-0.6	0.3	-1.5
Falls in the last year	1.0	1.4	3.5	-1.5	-1.1	-0.8	-0.4	-1.9	0.5	-1.4	0.8	-1.4
Hair/balding pattern: Pattern 3	0.3	0.4	1.5	-0.4	-1.2	-0.6	-0.1	-0.1	1.0	-0.6	0.4	-0.7
Number of live births	1.4	2.0	5.3	-0.4	0.5	1.0	-2.2	2.3	-0.9	1.8	-1.5	-0.4
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	10.7	0.4	-2.1	-0.9	3.3	-2.5	1.2	-2.5	1.6	-0.9
Pulse rate	0.3	0.5	3.0	0.4	1.7	0.6	-0.7	-0.2	0.2	-0.1	0.4	0.3
Happiness	0.5	0.6	1.6	-1.0	0.8	-1.0	0.7	0.0	1.3	0.2	0.2	-0.7
Noisy workplace	0.5	0.7	2.2	-0.9	-0.2	-0.2	0.7	1.5	-0.5	1.2	-0.9	-0.1
Qualifications: A levels/AS levels or equivalent	0.7	1.5	4.0	-2.0	-0.4	-1.7	-0.2	-0.8	1.2	-1.0	1.2	-1.4
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.5	4.4	-1.0	-1.3	-2.0	0.4	-1.6	1.2	-1.7	1.9	-2.1
Mouth/teeth dental problems: Dentures	0.8	1.4	2.6	-0.1	1.0	1.2	-1.4	1.6	-1.5	1.1	-1.0	0.9
Asthma	11.4	22.5	61.9	0.6	6.9	7.0	0.8	-0.3	-3.4	3.6	-4.2	7.9
Medication: Ibuprofen (e.g. Nurofen)	18.8	23.9	53.9	-4.7	-4.3	-6.7	-2.7	-2.9	5.7	-3.6	3.8	-7.3
Medication: Cholesterol lowering	0.3	0.4	0.9	-0.0	1.0	-0.9	-0.9	0.3	0.4	-0.3	0.8	-0.3
Depression (self-reported)	1.3	1.5	4.2	-2.0	-0.8	-1.5	-1.1	0.5	1.2	0.8	-0.8	-1.5
Medication: Lansoprazole	0.4	0.4	2.6	0.1	-1.6	-0.1	-0.7	-0.5	-0.3	-0.3	-0.3	-0.3
Prospective memory result	2.6	3.2	6.2	2.2	1.8	1.4	-0.5	2.4	-2.5	1.2	-1.2	1.9
Lung cancer (father)	0.6	0.6	2.8	0.1	-0.9	0.3	1.7	-0.4	-0.8	-0.9	0.6	-0.4
Illnesses of mother	0.2	0.2	0.7	-0.2	-0.8	0.1	-0.5	-0.8	-0.6	-0.2	-0.0	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	9.7	1.2	-2.1	-0.9	3.1	-2.1	1.2	-2.3	1.6	-0.7
Pulse wave Arterial Stiffness index	0.6	0.7	1.7	0.2	1.1	-1.3	-0.4	0.0	0.9	-0.5	0.5	-1.3
Impedance of arm (left)	0.6	2.9	8.1	1.0	0.7	2.9	2.3	0.5	-0.4	1.1	-1.8	2.5
Arm fat mass (right)	0.2	0.8	2.3	1.5	-0.2	0.4	-0.1	-1.3	-1.0	-0.6	0.8	1.2
Trunk predicted mass	3.1	17.9	38.5	-2.9	-3.0	-6.2	-1.0	-4.0	5.0	-4.1	4.2	-5.4
Standing height	2.4	23.5	45.0	-3.7	-3.8	-6.6	0.6	-4.4	6.7	-4.7	3.8	-6.2
Length of working week for main job	1.5	1.7	5.2	0.4	2.3	1.6	0.8	0.2	-1.6	0.1	-0.4	1.9
Exposure to tobacco smoke at home	0.9	1.0	1.5	1.2	1.2	1.1	-0.9	1.2	-1.0	0.5	-0.5	1.1
Breastfed as a baby	0.3	0.4	1.6	0.3	-0.3	-1.3	-0.8	-0.4	0.3	-0.5	0.8	-0.5
Tense / ‘highly strung’	1.4	2.4	9.6	0.5	1.1	1.5	3.1	0.5	-0.5	0.8	-1.2	2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.7	8.1	-1.8	-0.1	-1.9	-0.9	-0.8	2.9	-0.8	1.2	-2.3
Hair/balding pattern: Pattern 4	0.3	0.7	1.6	0.6	-1.0	-1.0	-1.3	-0.0	0.4	-0.8	1.2	-0.5
Birth weight of first child	1.4	2.6	7.7	-0.7	-2.0	-2.8	0.0	-0.3	1.4	-1.1	1.7	-2.3
Peak expiratory flow (PEF)	0.4	0.9	2.9	0.6	-0.3	0.7	1.7	-1.6	-0.2	-1.1	0.7	0.4
Pulse wave reflection index	1.7	2.1	5.7	0.1	-1.7	-2.4	-0.4	-0.5	1.6	-0.9	0.8	-2.4
Ever highly irritable/argumentative for 2 days	0.6	0.8	3.6	-1.5	-0.1	-0.2	-1.9	-0.4	0.5	-0.2	0.6	-0.1
Loud music exposure frequency	0.8	0.9	2.7	-1.7	-0.6	0.8	-0.7	-0.0	-1.4	0.5	-0.9	0.5
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	6.8	-2.6	-0.7	-1.5	-1.0	-1.0	1.2	-1.0	0.8	-1.6
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.4	-0.4	0.4	0.1	0.5	-0.2	-0.4	0.1	-0.1	0.6
Blood clot in the leg (DVT)	0.6	0.8	1.7	0.7	0.3	1.3	-0.2	1.1	-0.7	1.1	-1.0	0.9
Medication: Paracetamol	8.8	14.5	40.7	-5.4	-2.0	-4.5	-3.7	-0.7	4.5	-0.8	1.4	-6.4
Headache pain in last month	24.9	42.9	121.0	-8.0	-3.4	-8.7	-2.6	-3.2	8.5	-3.4	3.7	-11.0
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.7	0.1	-0.6	1.3	-0.1	-0.0	-0.2	0.7	-1.0	0.4
Glaucoma (self-reported)	0.8	0.9	3.7	-1.9	-1.0	-0.6	-1.2	0.4	0.6	0.4	-0.4	-1.0
Gout (self-reported)	2.1	2.9	8.9	-2.3	-0.6	-1.8	-0.7	0.2	2.6	-0.2	1.1	-3.0
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	11.0	-1.4	3.3	0.9	-0.4	0.8	0.6	2.1	-2.4	0.8
Medication: Amlodipine	0.3	0.4	1.2	-0.0	-0.4	0.4	-0.5	1.1	-1.0	0.3	-0.1	1.0
Medication: Ventolin 100micrograms inhaler	7.7	9.9	22.8	0.4	3.5	4.2	-0.9	2.0	-3.0	3.3	-3.4	4.8
Birth weight	2.8	6.1	13.3	-0.7	-1.3	-3.6	-0.1	-2.2	3.4	-2.5	2.6	-3.0
Chronic bronchitis/emphysema (mother)	0.7	0.8	3.7	-1.3	1.9	0.5	-0.2	0.1	0.5	0.6	-0.5	0.9
High blood pressure (siblings)	2.9	4.2	10.8	-2.2	-0.8	-2.1	0.4	-1.9	2.5	-2.0	1.7	-3.3
Forced vital capacity (FVC), Best measure	2.3	8.3	11.6	-0.4	-3.2	-3.2	2.9	-2.9	3.4	-3.1	2.5	-3.0
Body fat percentage	0.9	3.6	9.8	3.1	0.6	2.4	0.7	0.2	-2.5	0.6	-0.5	3.1
Leg fat percentage (right)	1.1	3.8	12.0	3.5	0.4	1.9	1.0	0.1	-2.6	0.1	0.1	3.2
Arm fat-free mass (right)	1.8	9.2	21.7	-1.4	-2.0	-4.7	-0.8	-3.0	3.2	-3.1	3.2	-3.9
Exposure to tobacco smoke outside home	0.7	0.9	2.7	-0.2	1.0	-1.1	-0.3	0.0	-0.2	-1.5	1.6	-0.9
Comparative body size at age 10	0.6	1.7	4.9	-0.1	-0.3	-1.2	0.0	-1.9	0.5	-2.0	2.2	-1.0
Number of full brothers	0.2	0.2	0.7	-0.3	-0.8	0.4	-0.8	0.4	-0.6	0.1	-0.2	-0.1
Worry too long after embarrassment	0.5	0.8	2.1	0.2	-1.0	-1.3	-0.3	0.4	1.4	0.0	0.1	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	1.7	-0.9	0.7	-0.3	-1.1	1.2	0.4	1.1	-1.2	-1.3
Wheeze or whistling in the chest in last year	2.3	4.1	18.5	-1.0	4.3	2.7	-0.7	-0.5	-0.9	0.9	-1.0	2.6
Number of children fathered	0.4	0.5	1.7	-1.3	-0.6	-0.6	-1.0	-0.1	0.1	-0.6	0.3	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.5	1.2	-0.9	0.4	0.7	-0.2	0.2	-0.0	0.2	0.7
Age at first live birth	0.3	0.6	1.3	1.1	0.9	-0.4	1.0	-0.5	0.8	-0.7	0.6	0.2
Pulse wave peak to peak time	0.4	0.4	1.3	-0.6	-1.2	0.9	0.5	-0.3	-0.4	0.2	-0.2	0.9
Health satisfaction	0.9	1.2	2.5	-1.6	-0.4	0.0	-1.4	1.5	-0.9	1.2	-1.1	-0.6
Shortness of breath walking on level ground	1.3	1.6	3.0	-0.8	-0.3	0.9	-1.3	1.6	-1.6	1.6	-1.7	-0.3
Qualifications: College or University degree	0.8	2.4	5.1	-0.2	-1.1	-1.7	0.7	-1.5	2.2	-1.8	1.7	-1.9
Eye problems/disorders: None of the above	0.4	0.5	1.4	1.0	-0.8	0.2	1.2	-0.2	-1.0	-0.1	0.1	0.4
Mouth/teeth dental problems: Loose teeth	1.0	1.2	4.0	-0.8	0.1	-0.2	1.1	-2.0	0.7	-1.4	1.3	-0.7
Emphysema/chronic bronchitis	1.6	1.8	3.8	-0.5	1.8	1.6	-0.3	1.2	-0.4	1.7	-1.9	1.3
Medication for pain relief, constipation, heartburn	13.1	22.4	63.3	6.4	2.2	5.8	4.0	1.3	-5.8	1.7	-2.2	8.0
Neck or shoulder pain in last month	0.9	1.3	6.2	-2.5	0.5	-0.2	-1.5	0.0	0.2	0.5	-0.9	-1.4
Medication: Blood pressure	0.2	0.4	1.3	-0.7	0.8	-1.1	0.4	0.6	-0.5	-0.3	0.5	-0.3
Angina (self-reported)	0.4	0.6	1.5	-0.5	-0.7	-0.5	-1.2	0.0	-0.4	-0.9	1.2	-0.2
Migraine (self-reported)	25.6	31.8	87.8	-6.3	-5.3	-7.7	-0.8	-3.3	5.1	-4.0	4.2	-9.4
Medication: Ibuprofen	14.2	17.0	39.3	-4.4	-2.9	-5.8	-2.7	-2.2	4.9	-2.8	3.0	-6.3
Medication: Allopurinol	1.1	1.5	4.2	-1.2	-0.2	-1.3	-0.2	0.0	2.0	-0.6	1.3	-2.1
Medication: Omeprazole	0.9	1.1	2.5	-1.6	-0.9	-0.8	-0.5	-0.8	1.6	-0.8	0.3	-1.2
Medication: Seretide 50 evohaler	3.6	4.1	10.5	-1.1	1.1	3.2	-0.0	1.1	-1.5	2.3	-2.3	3.2
Mean time to correctly identify matches	0.5	0.9	4.1	0.7	0.3	-0.1	-2.0	1.3	1.2	0.6	0.1	-0.6
Heart disease (mother)	0.3	0.4	1.4	-0.5	0.8	-0.5	-0.4	-0.2	1.2	-0.4	0.4	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.9	-0.8	-0.5	-0.7	0.6	0.1	-0.7	-0.6	1.0	-0.2
Whole body fat mass	0.3	1.1	4.2	2.0	-0.1	0.6	0.6	-1.0	-1.0	-0.5	0.6	1.4
Leg fat mass (right)	0.3	1.3	5.1	2.3	-0.3	0.3	0.5	-1.1	-1.2	-0.8	1.0	1.5
Arm predicted mass (right)	1.7	8.9	21.3	-1.3	-1.7	-4.6	-0.9	-2.9	3.3	-2.9	3.1	-3.9
Pulse rate, automated reading	0.2	0.7	2.5	1.0	1.6	0.7	-0.2	0.8	-0.9	0.6	-0.4	0.8
Alcohol intake frequency.	4.1	9.5	25.0	-3.3	-0.6	-4.3	-2.1	-1.7	3.9	-1.5	2.4	-5.0
Comparative height size at age 10	0.6	3.3	8.9	-1.8	-1.1	-2.2	-0.9	-1.9	3.0	-1.6	0.9	-2.0
Number of full sisters	0.2	0.2	1.3	-0.1	-0.1	0.3	-1.1	-0.3	0.4	0.1	0.1	0.5
Suffer from ‘nerves’	0.2	0.3	0.7	-0.8	-0.3	0.1	-0.4	0.8	-0.4	0.5	-0.7	-0.1
Overall health rating	1.2	2.5	5.0	-0.6	2.2	2.2	-0.3	1.0	-0.9	1.9	-2.1	1.7
Chest pain or discomfort	1.4	2.0	6.1	-2.5	1.9	1.2	-1.4	0.7	-0.8	1.1	-1.4	0.6
Had major operations	1.6	1.8	5.0	-1.4	-0.6	-1.4	-0.8	-0.9	1.4	-1.2	1.5	-2.2
Age at last live birth	0.4	0.6	2.0	1.2	1.4	0.3	0.4	-0.3	-1.0	-0.5	0.5	0.5
Family relationship satisfaction	0.3	0.3	1.3	-0.7	0.6	-0.5	-0.4	1.1	0.0	0.6	-0.2	-0.0
Leg pain on walking	0.2	0.3	1.0	-0.2	0.8	0.7	-0.5	-0.0	0.5	0.2	-0.1	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.8	-0.2	-0.1	0.3	-0.5	-0.2	-0.1	0.3	-0.6	-0.9
Commuting to job workplace: Car/motor vehicle	2.0	2.3	4.5	2.1	0.7	2.0	-0.0	1.3	-1.8	1.2	-1.4	1.7
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.8	1.3	0.3	0.5	0.8	0.2	-0.6	-0.3	0.2	1.2
Medication: Aspirin	0.9	1.2	3.3	-1.8	1.1	-0.7	-0.6	1.1	0.9	0.5	-0.4	-1.6
Supplements: Vitamin C	2.7	3.2	6.1	-1.7	-1.8	-2.0	0.8	-1.9	1.4	-1.9	1.6	-2.5
Knee pain experienced in last month	0.7	1.0	3.1	0.0	0.8	1.7	0.1	-1.4	-0.7	-0.2	0.2	1.8
Hypertension (Self-reported)	0.2	0.5	2.4	-1.0	1.6	-0.4	-0.2	0.6	-0.4	-0.2	0.2	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.4	-0.2	-1.0	-1.4	-0.3	-1.4	0.9	-1.5	1.5	-0.9
Illnesses of father: Heart disease	0.1	0.2	0.8	-0.3	-0.3	0.1	-0.9	0.0	0.0	-0.4	0.6	0.6
Illnesses of siblings: Diabetes	3.0	3.7	6.1	0.3	-2.1	-2.4	0.2	-2.1	2.0	-2.1	2.5	-1.9
Smoking status: Previous	0.6	1.0	3.1	-0.0	-1.2	-0.8	0.1	-0.5	0.2	-1.2	1.3	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.8	8.5	-2.4	-1.1	-2.9	-0.5	-1.2	2.0	-1.9	1.8	-2.5
Whole body fat-free mass	2.4	13.4	28.2	-2.2	-2.2	-5.3	-0.9	-3.9	4.2	-3.7	3.8	-4.6
Leg fat-free mass (right)	1.6	8.4	16.3	-1.6	-1.3	-4.0	-0.7	-3.7	3.2	-3.0	3.1	-3.5
Arm fat percentage (left)	0.8	3.1	8.7	2.3	1.2	2.4	0.4	-0.2	-2.5	0.5	-0.3	3.0
Average weekly red wine intake	0.5	0.8	1.5	0.0	0.7	0.7	0.7	0.4	-1.2	1.0	-1.2	1.2
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.1	-1.1	0.2	-0.2	-0.3	-0.9	0.3	-0.3	0.0	-0.1
Mood swings	2.0	3.7	8.7	-2.0	0.5	-2.6	-0.9	-0.6	3.0	-1.0	1.5	-2.9
Loneliness, isolation	2.6	3.7	7.6	-2.1	2.8	1.1	-1.9	2.1	-0.8	2.3	-2.3	0.4
Long-standing illness, disability or infirmity	0.4	0.6	1.5	-1.2	1.2	0.4	-0.4	-1.2	0.5	-0.0	-0.1	0.4
Ever had bowel cancer screening	1.2	1.4	2.4	-0.6	-1.2	-0.2	-1.4	-1.3	1.6	-1.3	1.4	-1.1
Diabetes diagnosed by doctor	0.3	0.4	1.0	0.7	0.7	0.4	-1.0	-0.5	-0.8	-0.5	0.6	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.6	-1.3	-0.6	-0.2	-0.5	1.0	0.4	0.6	-0.3	-0.8
Friendships satisfaction	0.7	0.9	4.0	-2.0	0.9	-0.1	-0.8	0.5	-0.2	1.0	-0.8	0.3
Qualifications: nursing, teaching	0.3	0.4	2.0	0.6	1.0	-0.1	1.4	-0.0	-0.1	-0.2	0.0	0.3
Commuting to job workplace: Walk	0.5	0.5	2.1	-1.4	0.5	-0.1	-0.6	-0.8	0.4	-0.7	0.8	-0.2
Eye problems/disorders: Cataract	2.5	2.9	5.5	-1.0	-0.8	-2.2	-0.9	-1.5	2.3	-1.7	1.7	-2.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.6	-0.1	-0.6	-0.0	-0.3	-0.7	0.8	-1.1	1.3	-0.7
Medication for cholesterol	1.5	2.3	5.3	1.4	-2.3	-1.0	1.2	-2.1	0.4	-1.7	1.6	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.3	-0.3	-1.0	-0.4	-1.8	0.8	0.1	0.3	-0.2	-1.0
Back pain experienced in last month	2.3	3.3	7.9	-2.7	-1.5	-1.9	-2.6	-0.0	1.2	-0.0	-0.1	-2.8
Mineral and other dietary supplements	4.0	5.4	16.2	2.3	2.8	2.9	0.6	1.5	-2.0	1.2	-1.7	4.0
Breast cancer (self-reported)	0.6	0.7	1.9	0.5	0.4	1.0	-0.7	0.2	0.2	0.9	-1.2	1.4
Asthma (self-reported)	12.0	24.0	65.1	0.9	6.8	7.4	0.7	0.1	-3.7	3.9	-4.5	8.1
Osteoporosis (self-reported)	0.3	0.3	1.0	0.2	0.1	1.0	0.3	-0.4	0.6	0.7	-0.8	-0.0
Osteoarthritis (self-reported)	0.3	0.5	1.4	-0.9	-0.4	-0.2	0.5	-1.2	0.8	-0.8	0.3	-0.3
Medication: Aspirin	1.0	1.3	3.4	-1.8	1.0	-1.0	-0.8	0.8	1.2	0.3	-0.3	-1.8
Medication: Gliclazide	0.9	1.0	2.6	-0.9	1.6	0.9	-1.5	0.2	-1.4	0.5	-0.3	0.2
Illnesses of father: None of the above (group 1)	0.2	0.3	0.9	-0.4	0.7	0.4	1.0	-0.5	0.4	0.0	-0.2	-0.5
Smoking status: Current	0.9	1.4	2.6	-1.0	-1.2	-1.5	-1.4	0.2	1.2	-0.7	0.9	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	5.3	1.7	-0.6	0.7	2.3	-0.1	-0.9	-0.5	0.2	0.9
Whole body water mass	2.4	13.5	28.5	-2.2	-2.2	-5.3	-0.9	-3.9	4.2	-3.7	3.8	-4.6
Leg predicted mass (right)	1.6	8.3	16.1	-1.5	-1.2	-4.0	-0.7	-3.7	3.2	-3.0	3.1	-3.4
Arm fat mass (left)	0.2	0.6	1.7	1.3	0.1	0.3	-0.1	-1.1	-0.9	-0.5	0.7	1.0
Number of self-reported non-cancer illnesses	0.5	0.9	2.7	-1.5	1.6	0.9	-0.6	-0.4	0.6	0.7	-0.8	0.1
Average weekly champagne plus white wine intake	0.5	0.7	2.0	0.0	-0.9	-1.4	-0.2	-0.9	1.2	-0.8	0.9	-0.4
Miserableness	4.7	8.2	24.3	-2.1	-1.5	-3.4	-0.5	-2.5	4.9	-2.4	2.7	-3.6
Guilty feelings	0.1	0.2	0.5	0.2	0.0	0.4	-0.7	0.4	0.3	0.4	-0.3	0.6
Wears glasses or contact lenses	0.5	0.6	3.2	0.6	-1.8	0.6	-0.7	0.1	-0.6	-0.5	0.3	0.4
Ever taken oral contraceptive pill	0.4	0.5	1.1	-1.0	-0.8	-1.0	0.6	0.4	0.0	-0.3	0.4	-1.0
Hearing aid user	1.1	1.2	3.1	-1.6	1.8	-0.6	-1.3	0.4	1.3	0.7	-0.6	-0.7
Mother’s age at death	0.6	0.7	3.6	-1.9	-1.1	-0.2	-0.6	0.1	0.0	0.1	-0.4	-1.0
Financial situation satisfaction	1.4	1.8	4.2	-1.3	-0.3	0.4	-1.6	2.0	-1.2	2.0	-1.5	-0.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.4	1.0	-0.1	-0.6	1.2	-0.6	0.8	-0.8	0.7	0.5
Commuting to job workplace: Public transport	0.3	0.4	1.5	-1.2	-0.7	-0.7	0.4	-0.4	0.6	-0.4	0.2	-0.3
Eye problems/disorders: Glaucoma	0.7	0.9	2.8	-1.7	-0.2	-1.1	-0.1	-0.8	1.1	-0.6	0.7	-1.2
Medication: Blood pressure	0.8	1.5	6.9	-0.4	2.6	1.1	-0.1	1.4	-0.5	1.2	-1.2	0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.0	-0.2	0.7	1.4	-0.8	-0.5	0.2	0.2	-0.4	1.2
Supplements: Fish oil (including cod liver oil)	3.7	4.8	14.8	-2.9	-1.7	-2.9	-0.5	-1.4	1.9	-1.0	1.6	-3.8
High cholesterol (Self-reported)	1.5	2.7	6.3	0.3	2.1	0.9	-1.5	2.5	-2.1	1.7	-1.6	0.7
Medication: Bendroflumethiazide	1.2	1.7	5.9	0.6	2.4	1.3	0.6	0.9	-1.2	1.4	-1.3	1.3
Medication: Paracetamol	5.9	9.2	26.1	-4.0	-1.2	-3.5	-3.2	-0.6	3.9	-0.3	0.9	-5.1
Medication: Lisinopril	2.4	3.1	5.9	1.5	2.4	2.2	1.7	1.4	-1.7	1.0	-1.0	2.2
Medication: Atorvastatin	1.2	1.5	6.3	-1.0	2.5	1.2	0.6	0.1	-0.9	0.6	-0.9	1.5
Illnesses of father: High blood pressure	2.5	3.0	5.2	-2.1	-1.0	-2.3	1.4	-1.4	1.4	-2.0	1.6	-2.0
Alcohol drinker status: Never	1.4	1.7	4.2	-1.3	-1.1	-2.0	-0.7	-0.6	1.9	-0.8	1.2	-1.4
Ever smoked	1.7	3.1	7.2	-1.0	-1.2	-1.9	-1.1	-0.9	0.6	-2.4	2.5	-2.7
Basal metabolic rate	1.8	10.0	20.7	-1.6	-1.9	-4.5	-0.7	-3.7	3.5	-3.4	3.4	-3.7
Leg fat percentage (left)	1.1	4.1	11.6	3.4	0.4	2.0	0.8	0.4	-3.0	0.4	-0.1	3.3
Arm fat-free mass (left)	1.8	9.1	21.7	-1.2	-2.1	-4.7	-1.1	-3.0	3.3	-3.0	3.2	-3.7
Number of operations (self-reported)	3.6	5.4	15.2	-2.9	-1.1	-2.3	-2.0	-1.7	2.5	-1.5	1.5	-3.9
Average weekly beer plus cider intake	4.8	7.0	16.9	2.3	1.4	4.1	-0.5	1.7	-3.5	2.3	-2.6	3.3
Irritability	0.2	0.3	1.4	0.4	-0.1	-0.1	1.2	0.7	0.4	0.1	0.4	0.0
Risk taking	0.5	0.7	2.2	-0.4	-0.1	-0.3	0.4	-1.2	-0.8	-1.5	1.4	0.0
Ever had prostate specific antigen (PSA) test	1.5	1.8	3.8	-0.9	-0.9	-1.9	-0.8	-0.8	1.9	-0.9	1.2	-1.9
Fractured/broken bones in last 5 years	0.4	0.5	1.4	0.6	1.0	1.2	0.1	0.2	-0.1	-0.1	-0.2	1.2
Age started oral contraceptive pill	1.8	2.2	7.2	0.5	0.6	0.7	-1.8	2.7	-1.5	1.7	-1.8	0.1
Diastolic blood pressure, automated reading	0.3	0.9	3.7	0.6	0.9	0.2	-1.1	1.9	0.6	0.9	-0.7	0.3
Ever depressed for a whole week	0.4	0.5	1.5	-0.8	-0.0	-0.8	0.6	-0.2	1.1	-0.3	1.2	-0.3
Unable to work because of sickness or disability	1.3	1.6	3.4	0.0	1.1	1.0	-1.4	1.7	-0.6	1.8	-1.6	1.2
Commuting to job workplace: Cycle	2.1	2.5	4.3	0.4	1.6	1.5	-0.7	2.1	-2.0	1.6	-1.7	1.7
Myopia	7.1	10.4	25.4	-2.2	-5.0	-3.6	-0.5	-2.3	3.3	-2.7	2.4	-4.6
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.6	0.9	-1.3	0.4	0.4	-1.1	0.2	0.0	-0.4	0.1
Cholesterol lowering medication	0.8	1.2	2.6	-0.8	1.6	1.1	-0.7	1.1	-1.4	1.1	-1.1	0.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.0	-1.0	-1.0	-0.1	-1.0	-0.4	0.7	-0.4	0.0	-0.8
Pain experienced in last month	5.6	9.4	25.9	5.1	1.6	3.8	1.9	1.0	-3.2	0.6	-0.9	5.0
Supplements: Calcium	4.1	4.5	8.9	-0.9	-1.8	-2.4	-0.7	-2.8	1.2	-2.7	2.2	-3.0
Basal cell carcinoma (self-reported)	0.5	0.6	1.7	-0.6	-1.3	-0.0	-0.7	-0.4	0.8	-0.7	0.8	-0.8
Heart attack/myocardial infarction (self-reported)	0.5	0.6	3.8	-1.9	0.6	0.2	-1.0	0.3	-0.0	0.0	-0.1	0.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.0	0.8	0.2	1.0	-0.2	0.7	-0.1	0.9	-0.8	0.6
Heart disease (siblings)	1.0	1.2	3.4	-0.6	1.6	0.8	-1.9	1.3	0.4	1.1	-1.0	0.4
Alcohol drinker status: Previous	0.7	0.8	3.7	-1.6	-0.4	-0.4	-0.2	0.4	0.2	0.5	-0.6	-1.9
Pack years of smoking	0.5	0.8	2.7	0.3	1.6	0.7	1.1	0.4	-0.3	0.8	-0.7	1.0
Impedance of whole body	0.7	3.5	7.8	1.8	0.2	2.8	2.4	1.4	-0.7	1.3	-2.0	2.5
Leg fat mass (left)	0.3	1.3	5.1	2.2	-0.3	0.3	0.3	-1.0	-1.4	-0.8	0.9	1.5
Arm predicted mass (left)	1.8	9.1	21.2	-1.3	-2.3	-4.6	-0.8	-3.0	3.1	-3.1	3.2	-3.8