416 significantly associated models · 38 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 173885712 | 175194390 | 1 | 1 | 1.3e-07 | 2.6e-09 | 1.0e+00 | 100 | RABGAP1L |
2 | 1 | 242590540 | 244359621 | 3 | 1 | 6.7e-11 | 8.2e-11 | 3.3e-01 | 98 | SDCCAG8 |
3 | 3 | 48618666 | 50448632 | 6 | 1 | 7.0e-08 | 2.5e-06 | 3.4e-01 | 96 | RNF123 |
4 | 6 | 12020241 | 13990267 | 2 | 1 | 3.3e-08 | 1.8e-08 | 1.0e+00 | 100 | RP1-257A7.5 |
5 | 6 | 25285943 | 26689223 | 1 | 1 | 1.3e-11 | 2.8e-13 | 8.8e-05 | 71 | U91328.21 |
6 | 6 | 96275538 | 97699026 | 2 | 1 | 9.8e-09 | 8.4e-10 | 2.4e-02 | 86 | KIAA0776 |
7 | 8 | 140969818 | 142706843 | 1 | 1 | 4.8e-08 | 1.3e-04 | 8.4e-01 | 100 | PTK2 |
8 | 9 | 125444045 | 127385609 | 1 | 1 | 1.5e-07 | 7.8e-07 | 7.0e-01 | 99 | DENND1A |
9 | 12 | 56805309 | 58303535 | 2 | 1 | 1.2e-18 | 2.1e-18 | 1.0e+00 | 100 | LRP1 |
10 | 17 | 42774693 | 45796313 | 19 | 1 | 4.3e-15 | 7.4e-15 | 1.0e+00 | 100 | LRRC37A4P |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Artery Coronary | 10 | 0.845 | 2.1 |
GTEx | Uterus | 6 | 1.058 | 2.1 |
GTEx | Brain Putamen basal ganglia | 5 | 0.801 | 2.0 |
GTEx | Small Intestine Terminal Ileum | 4 | 0.868 | 2.0 |
GTEx | Vagina | 5 | 0.787 | 2.0 |
GTEx | Brain Hippocampus | 4 | 0.763 | 1.9 |
GTEx | Brain Hypothalamus | 4 | 0.678 | 1.9 |
GTEx | Brain Nucleus accumbens basal ganglia | 6 | 0.694 | 1.9 |
GTEx | Cells EBV-transformed lymphocytes | 9 | 0.632 | 1.9 |
GTEx | Colon Sigmoid | 7 | 0.479 | 1.9 |
GTEx | Esophagus Gastroesophageal Junction | 8 | 0.554 | 1.9 |
GTEx | Ovary | 6 | 0.661 | 1.9 |
GTEx | Pancreas | 7 | 0.429 | 1.9 |
GTEx | Prostate | 5 | 0.599 | 1.9 |
GTEx | Adipose Visceral Omentum | 6 | 0.295 | 1.8 |
GTEx | Artery Aorta | 11 | 0.369 | 1.8 |
GTEx | Artery Tibial | 10 | 0.266 | 1.8 |
GTEx | Brain Cerebellum | 7 | 0.353 | 1.8 |
GTEx | Brain Cortex | 7 | 0.676 | 1.8 |
GTEx | Brain Frontal Cortex BA9 | 6 | 0.649 | 1.8 |
GTEx | Breast Mammary Tissue | 9 | 0.456 | 1.8 |
GTEx | Breast Mammary Tissue (Male) | 7 | 0.587 | 1.8 |
GTEx | Breast Mammary Tissue (Female) | 8 | 0.487 | 1.8 |
GTEx | Colon Transverse | 9 | 0.436 | 1.8 |
GTEx | Esophagus Muscularis | 11 | 0.340 | 1.8 |
GTEx | Liver | 4 | 0.558 | 1.8 |
GTEx | Pituitary | 5 | 0.448 | 1.8 |
GTEx | Skin Not Sun Exposed Suprapubic | 8 | 0.325 | 1.8 |
GTEx | Skin Sun Exposed Lower leg | 9 | 0.247 | 1.8 |
GTEx | Stomach | 7 | 0.481 | 1.8 |
GTEx | Testis | 10 | 0.317 | 1.8 |
GTEx | Adipose Subcutaneous | 9 | 0.258 | 1.7 |
GTEx | Adrenal Gland | 5 | 0.343 | 1.7 |
GTEx | Brain Caudate basal ganglia | 6 | 0.652 | 1.7 |
GTEx | Brain Cerebellar Hemisphere | 6 | 0.403 | 1.7 |
GTEx | Cells Transformed fibroblasts | 10 | 0.238 | 1.7 |
GTEx | Esophagus Mucosa | 11 | 0.331 | 1.7 |
GTEx | Heart Atrial Appendage | 8 | 0.507 | 1.7 |
GTEx | Heart Left Ventricle | 7 | 0.458 | 1.7 |
GTEx | Lung | 9 | 0.313 | 1.7 |
GTEx | Muscle Skeletal | 8 | 0.277 | 1.7 |
GTEx | Nerve Tibial | 9 | 0.208 | 1.7 |
GTEx | Spleen | 5 | 0.354 | 1.7 |
GTEx | Thyroid | 10 | 0.250 | 1.7 |
GTEx | Whole Blood | 6 | 0.301 | 1.7 |
The Cancer Genome Atlas | Esophageal Carcinoma | 3 | 0.438 | 1.7 |
NTR | Blood | 4 | 0.167 | 1.6 |
ROSMAP | Brain Pre-frontal Cortex | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 3 | 0.181 | 1.6 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 3 | 0.273 | 1.6 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 1 | 0.098 | 1.6 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 5 | 0.170 | 1.6 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 4 | 0.160 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 4 | 0.241 | 1.6 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 4 | 0.301 | 1.6 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 3 | 0.434 | 1.6 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 4 | 0.375 | 1.6 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.187 | 1.6 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 2 | 0.394 | 1.6 |
METSIM | Adipose | 2 | 0.043 | 1.5 |
YFS | Blood | 0 | 0.000 | 1.5 |
CommonMind | Brain Pre-frontal Cortex | 4 | 0.074 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 2 | 0.045 | 1.5 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 2 | 0.073 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 6 | 0.146 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 2 | 0.098 | 1.5 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 4 | 0.093 | 1.5 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 3 | 0.271 | 1.5 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 4 | 0.251 | 1.5 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 8 | 0.173 | 1.5 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 3 | 0.178 | 1.5 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 1 | 0.078 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 4 | 0.078 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 1 | 0.048 | 1.4 |