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chr1:9,576,675-11,170,131

Best TWAS P=6.66e-09 · Best GWAS P=6.44e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	PGD	0.15	0.10	lasso	2	0.02	4.3e-02	-5.7	-5.6	1.6e-08	0.99	0.01	0.93	FALSE
2	GTEx	Cells EBV-transformed lymphocytes	PGD	0.17	0.14	lasso	6	0.08	1.7e-03	-5.6	-5.3	1.2e-07	0.91	0.02	0.95	FALSE
3	GTEx	Cells Transformed fibroblasts	PGD	0.47	0.56	enet	15	0.55	7.5e-49	-5.8	-5.7	1.1e-08	1.00	0.01	0.99	FALSE
4	GTEx	Esophagus Muscularis	PGD	0.07	0.05	enet	9	0.05	4.8e-04	-5.8	-5.6	2.6e-08	0.94	0.03	0.96	FALSE
5	GTEx	Lung	KIF1B	0.09	0.11	lasso	2	0.10	7.8e-08	-5.6	-5.6	1.8e-08	0.97	0.01	0.99	FALSE
6	GTEx	Muscle Skeletal	PGD	0.14	0.15	enet	9	0.16	2.1e-15	-5.8	-5.7	9.9e-09	1.00	0.01	0.99	FALSE
7	GTEx	Stomach	PGD	0.10	-0.01	enet	10	0.00	3.9e-01	-5.8	-5.7	9.0e-09	0.99	0.02	0.97	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PGD	0.04	0.02	blup	52	0.03	2.6e-03	-5.8	-5.4	8.8e-08	0.92	0.01	0.92	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIF1B	0.05	0.01	blup	108	0.01	9.4e-04	-5.8	-5.4	7.1e-08	0.92	0.01	0.96	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	PGD	0.06	0.07	lasso	5	0.07	9.8e-15	-5.7	-5.6	2.1e-08	0.98	0.01	0.99	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	PGD	0.04	0.06	lasso	9	0.06	3.9e-07	-5.8	-5.8	6.7e-09	0.99	0.01	0.99	TRUE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PGD	0.06	0.00	enet	9	0.01	3.8e-02	-4.4	-5.1	3.0e-07	0.90	0.01	0.70	FALSE
13	The Cancer Genome Atlas	Stomach Adenocarcinoma	KIF1B	0.04	0.03	blup	108	0.05	1.9e-04	-4.8	-5.2	2.0e-07	0.89	0.05	0.90	FALSE
14	The Cancer Genome Atlas	Stomach Adenocarcinoma	PGD	0.05	0.04	blup	51	0.03	2.8e-03	-5.8	-5.4	5.4e-08	0.96	0.01	0.96	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	PGD	0.06	0.05	enet	10	0.03	7.7e-04	-5.8	-5.6	1.9e-08	0.99	0.01	0.99	FALSE