TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Multivitamins +/- minerals
:
←
chr10:64,195,778-66,034,105
Best TWAS P=3.02e-08 · Best GWAS P=1.54e-08 conditioned to 0.17
64.5M
65M
65.5M
66M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
REEP3
0.10
0.03
lasso
3
0.03
7.2e-04
-5.6
5.5
3.0e-08
-0.93
0.01
0.98
TRUE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
NRBF2
0.10
0.06
lasso
7
0.08
3.5e-09
-5.5
-5.2
1.5e-07
0.83
0.00
1.00
FALSE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
REEP3
0.04
0.04
blup
59
0.05
1.8e-06
-5.7
5.2
1.5e-07
-0.83
0.01
0.99
FALSE
2
GTEx
Stomach
NRBF2
0.09
0.04
lasso
6
0.03
1.6e-02
-4.1
-5.2
1.8e-07
0.87
0.03
0.74
FALSE