Best TWAS P=3.02e-08 · Best GWAS P=1.54e-08 conditioned to 0.17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | REEP3 | 0.10 | 0.03 | lasso | 3 | 0.03 | 7.2e-04 | -5.6 | 5.5 | 3.0e-08 | -0.93 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Stomach | NRBF2 | 0.09 | 0.04 | lasso | 6 | 0.03 | 1.6e-02 | -4.1 | -5.2 | 1.8e-07 | 0.87 | 0.03 | 0.74 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NRBF2 | 0.10 | 0.06 | lasso | 7 | 0.08 | 3.5e-09 | -5.5 | -5.2 | 1.5e-07 | 0.83 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | REEP3 | 0.04 | 0.04 | blup | 59 | 0.05 | 1.8e-06 | -5.7 | 5.2 | 1.5e-07 | -0.83 | 0.01 | 0.99 | FALSE |