Best TWAS P=1.92e-08 · Best GWAS P=1.34e-07 conditioned to 0.107
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | KIF3B | 0.07 | 0.05 | blup | 355 | 0.06 | 2.6e-07 | -4.8 | -5.6 | 1.9e-08 | 0.75 | 0.09 | 0.90 | TRUE |
2 | METSIM | Adipose | C20orf112 | 0.06 | 0.08 | lasso | 4 | 0.08 | 1.2e-11 | -4.9 | -5.3 | 1.0e-07 | 0.95 | 0.04 | 0.95 | FALSE |
3 | YFS | Blood | ASXL1 | 0.03 | 0.02 | blup | 366 | 0.02 | 6.0e-08 | -4.8 | -5.5 | 3.9e-08 | 0.80 | 0.05 | 0.95 | FALSE |