Best TWAS P=8.56e-09 · Best GWAS P=3.3e-09 conditioned to 0.0327
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | DHX38 | 0.09 | -0.01 | enet | 8 | 0.00 | 4.5e-01 | -5.9 | 5.3 | 1.5e-07 | -0.82 | 0.04 | 0.72 | FALSE |
| 2 | GTEx | Spleen | PHLPP2 | 0.18 | 0.11 | lasso | 13 | 0.09 | 2.2e-03 | -4.5 | -5.2 | 1.6e-07 | 0.82 | 0.05 | 0.72 | FALSE |
| 3 | GTEx | Thyroid | IST1 | 0.06 | 0.03 | lasso | 6 | 0.03 | 4.6e-03 | -5.8 | -5.5 | 5.0e-08 | 0.95 | 0.03 | 0.94 | FALSE |
| 4 | YFS | Blood | ATXN1L | 0.02 | 0.02 | blup | 413 | 0.02 | 6.5e-07 | -5.9 | -5.8 | 8.6e-09 | 0.81 | 0.01 | 0.99 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | MARVELD3 | 0.08 | 0.01 | blup | 44 | 0.06 | 7.1e-07 | 3.7 | -5.4 | 7.1e-08 | 0.74 | 0.02 | 0.84 | FALSE |