[Hub]/) : Traits : Back pain experienced in last month :

chr10:73,027,892-74,809,596

Best TWAS P=1.31e-11 · Best GWAS P=7.54e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CHST3 0.12 0.12 lasso 6 0.11 1.1e-13 -6.6 -6.8 1.3e-11 0.98 0.02 0.98 TRUE
2 GTEx Adrenal Gland SPOCK2 0.44 0.46 lasso 15 0.46 3.5e-18 4.4 -5.5 5.0e-08 0.70 0.91 0.09 FALSE
3 GTEx Adrenal Gland DNAJB12 0.18 0.06 lasso 5 0.10 2.2e-04 -3.8 -5.3 1.1e-07 0.52 0.26 0.54 FALSE
4 GTEx Esophagus Muscularis ASCC1 0.16 0.03 enet 23 0.04 2.0e-03 3.1 -5.4 7.9e-08 0.46 0.52 0.16 FALSE
5 GTEx Muscle Skeletal SPOCK2 0.08 0.03 lasso 3 0.05 2.5e-05 3.1 5.2 2.4e-07 -0.76 0.28 0.70 FALSE
6 METSIM Adipose SPOCK2 0.06 0.06 lasso 10 0.07 1.3e-10 -6.0 5.2 1.8e-07 -0.80 0.12 0.88 FALSE
7 ROSMAP Brain Pre-frontal Cortex CHST3 0.15 0.18 lasso 5 0.18 1.1e-22 -6.3 -6.4 2.0e-10 0.96 0.07 0.93 FALSE
8 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CHST3 0.10 0.03 blup 99 0.04 5.8e-03 -6.0 -5.7 1.0e-08 0.89 0.02 0.51 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma CHST3 0.05 0.03 lasso 2 0.03 4.0e-04 3.8 -5.4 8.3e-08 0.59 0.15 0.77 FALSE