Best TWAS P=1.33e-10 · Best GWAS P=3.36e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARMS2 | 0.04 | 0.02 | lasso | 3 | 0.01 | 2.7e-02 | -5.3 | -6.2 | 5.2e-10 | 0.92 | 0.01 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ARMS2 | 0.23 | 0.20 | lasso | 2 | 0.21 | 7.0e-09 | -6.3 | -6.4 | 1.3e-10 | 0.99 | 0.00 | 1.00 | TRUE |