Best TWAS P=2.83e-08 · Best GWAS P=1.77e-08 conditioned to 0.123
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | MRPL51 | 0.08 | 0.05 | lasso | 4 | 0.02 | 5.6e-04 | 5.4 | 5.5 | 4.9e-08 | 0.89 | 0.01 | 0.99 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | CD27 | 0.12 | 0.02 | lasso | 5 | 0.03 | 2.4e-03 | 5.5 | 5.5 | 3.0e-08 | 0.90 | 0.01 | 0.96 | FALSE |
3 | NTR | Blood | MRPL51 | 0.05 | 0.03 | lasso | 6 | 0.04 | 3.1e-12 | 5.6 | 5.5 | 2.8e-08 | 0.89 | 0.01 | 0.99 | TRUE |