TWAS hub - MRPL51

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0780	0.0290	3.5e-04	0.046	0.021	0.010	0.023	0.024	2.8e-06	1.1e-03	1.7e-02	6.6e-04	5.6e-04
2	GTEx	Adipose Subcutaneous	0.3340	0.0450	0.0e+00	0.381	NA	0.397	NA	0.371	7.8e-33	NA	2.0e-34	NA	1.0e-31
3	GTEx	Adipose Visceral Omentum	0.2760	0.0560	1.8e-11	0.305	NA	0.281	NA	0.303	2.7e-16	NA	6.0e-15	NA	3.3e-16
4	GTEx	Brain Nucleus accumbens basal ganglia	0.5110	0.1240	1.3e-03	0.010	NA	0.001	NA	-0.008	1.7e-01	NA	3.0e-01	NA	6.1e-01
5	GTEx	Breast Mammary Tissue	0.2240	0.0560	2.5e-07	0.175	NA	0.160	NA	0.107	2.5e-09	NA	1.4e-08	NA	4.0e-06
6	GTEx	Breast Mammary Tissue (Male)	0.1396	0.0855	7.2e-02	0.027	NA	-0.011	NA	0.004	8.0e-02	NA	6.7e-01	NA	2.5e-01
7	GTEx	Breast Mammary Tissue (Female)	0.1490	0.0666	1.6e-02	0.197	NA	0.055	NA	0.149	1.6e-06	NA	9.9e-03	NA	3.4e-05
8	GTEx	Cells Transformed fibroblasts	0.2650	0.0480	0.0e+00	0.302	NA	0.301	NA	0.298	5.2e-23	NA	5.9e-23	NA	1.1e-22
9	GTEx	Lung	0.1448	0.0424	2.4e-06	0.133	NA	0.095	NA	0.116	2.5e-10	NA	9.7e-08	NA	3.4e-09
10	GTEx	Nerve Tibial	0.2877	0.0446	0.0e+00	0.357	NA	0.326	NA	0.337	2.5e-26	NA	1.2e-23	NA	1.5e-24
11	GTEx	Ovary	0.4070	0.1060	1.9e-05	0.206	NA	0.148	NA	0.166	8.4e-06	NA	1.8e-04	NA	7.2e-05
12	GTEx	Skin Sun Exposed Lower leg	0.0870	0.0330	7.0e-04	0.060	NA	0.007	NA	0.037	1.0e-05	NA	7.6e-02	NA	4.9e-04
13	GTEx	Testis	0.1940	0.0670	1.6e-03	0.078	NA	0.042	NA	-0.001	2.5e-04	NA	6.1e-03	NA	3.5e-01
14	METSIM	Adipose	0.0535	0.0167	8.2e-06	0.057	0.044	0.050	0.050	0.052	6.8e-09	3.5e-07	5.3e-08	5.6e-08	3.0e-08
15	NTR	Blood	0.0463	0.0126	1.5e-09	0.035	0.033	0.037	0.035	0.038	2.3e-11	6.4e-11	6.4e-12	1.8e-11	3.1e-12
16	ROSMAP	Brain Pre-frontal Cortex	0.0782	0.0211	8.7e-07	0.099	0.053	0.098	0.061	0.048	1.1e-12	2.2e-07	1.4e-12	2.9e-08	8.4e-07
17	YFS	Blood	0.0715	0.0154	0.0e+00	0.049	0.063	0.065	0.069	0.073	8.0e-16	6.8e-20	1.9e-20	1.6e-21	7.8e-23
18	TCGA	Brain Lower Grade Glioma	0.0255	0.0166	5.8e-03	0.013	0.012	0.008	NA	0.014	1.1e-02	1.6e-02	3.5e-02	NA	8.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Osteoarthritis (self-reported)	10.2	13.2	17.7	1.9	4.0	4.1	-1.3	3.7	4.1	4.0	4.2	4.2	4.1	4.0	4.1	2.1	4.2	3.1	-0.9	4.1	4.2
Back pain experienced in last month	6.4	9.4	30.8	5.5	1.8	2.1	1.7	1.5	2.3	1.7	3.1	2.3	2.4	2.0	2.3	-2.6	2.2	5.5	4.2	5.0	1.8
Length of working week for main job	5.0	5.5	8.8	-1.3	-2.5	-2.5	0.4	-2.7	-2.6	-2.9	-2.9	-2.9	-3.0	-2.6	-3.0	-1.3	-2.8	-0.9	0.8	-1.4	-2.7
Diabetes (father)	4.7	5.8	8.9	-0.8	-3.0	-2.6	2.0	-2.4	-2.6	-2.9	-2.7	-2.8	-2.8	-2.8	-2.9	-2.0	-2.8	-0.9	1.1	-1.4	-2.6
Hair/balding pattern: Pattern 2	4.4	5.6	8.0	-0.4	-2.6	-2.8	1.2	-2.6	-2.7	-2.7	-2.6	-2.7	-2.7	-2.8	-2.7	-2.3	-2.7	-1.4	1.3	-2.1	-2.7
Schizophrenia vs Biploar Disorder	4.1	5.4	12.0	2.9	2.1	2.0	2.5	1.6	2.1	1.9	2.7	2.5	2.3	2.1	2.3	-0.7	2.2	3.5	1.4	3.5	1.9
Ovarian Cancer	3.9	5.2	8.2	0.5	2.6	2.5	-1.0	2.2	2.2	2.8	2.7	2.6	2.9	2.8	2.8	2.1	2.8	0.8	-1.4	1.8	2.1
Exposure to tobacco smoke at home	3.7	4.2	5.9	0.0	-2.3	-1.8	2.3	-2.1	-2.2	-2.4	-2.2	-2.3	-2.3	-2.2	-2.3	-2.2	-2.2	-0.3	1.7	-1.3	-2.4
Breast cancer (self-reported)	3.5	4.2	9.1	1.0	-2.3	-2.9	0.3	-2.4	-2.1	-2.2	-1.7	-2.2	-2.1	-1.8	-2.0	-3.0	-2.3	0.7	2.5	-0.2	-2.3
Lupus	3.4	5.2	8.9	-0.8	-2.7	-3.0	0.6	-2.3	-2.8	-2.4	-2.4	-2.4	-2.5	-2.5	-2.5	-1.5	-2.6	-1.8	0.9	-2.7	-2.8
Hearing difficulty/problems: Yes	3.1	4.7	6.4	0.6	2.4	2.1	0.6	2.5	2.4	2.4	2.5	2.4	2.5	2.5	2.5	1.9	2.3	1.9	-1.0	2.4	2.4
Financial situation satisfaction	2.8	3.5	11.3	3.4	1.0	1.1	3.2	0.8	1.3	0.8	1.5	1.1	1.1	1.0	1.1	-1.7	1.1	3.1	2.6	2.6	0.9
Triglycerides	2.6	4.2	8.2	2.6	2.0	1.6	1.0	1.9	2.1	2.1	2.4	2.2	2.3	2.4	2.3	0.1	2.1	2.9	1.0	2.5	1.6
Pain all over the body in last month	2.5	2.7	11.0	-2.1	1.4	1.4	-2.2	1.4	1.1	1.3	0.6	1.0	0.9	1.0	1.0	3.3	1.2	-1.6	-2.9	-1.0	1.4
Loud music exposure frequency	2.5	2.7	7.4	-2.0	-1.5	-1.7	0.8	-1.3	-1.6	-1.4	-1.9	-1.7	-1.6	-1.4	-1.6	0.6	-1.7	-2.7	-1.0	-2.4	-1.4
Medication: Ibuprofen	2.4	2.9	5.2	1.2	1.9	2.3	-0.9	1.5	1.9	1.8	2.0	1.8	1.8	1.6	1.8	1.4	2.0	1.4	-0.2	1.7	1.9
Commuting to job workplace: Walk	2.4	2.6	10.9	2.4	-1.2	-0.8	1.5	-1.5	-0.9	-1.4	-0.7	-1.2	-1.1	-1.0	-1.1	-2.8	-1.0	1.9	3.3	0.8	-1.5
Crohns Disease (2017)	2.3	5.1	11.6	3.2	2.6	3.4	-0.6	1.7	2.5	2.0	2.5	2.1	2.2	2.0	2.2	-0.5	2.6	2.3	1.5	2.4	2.2
Illnesses of father: Heart disease	2.3	3.2	10.6	1.5	-1.8	-1.5	0.6	-2.0	-1.8	-1.9	-1.5	-1.7	-1.7	-1.6	-1.8	-3.3	-1.7	0.7	2.8	-0.2	-2.0
Medication: Ramipril	2.2	2.8	6.1	2.0	1.5	1.9	0.1	1.5	1.5	1.5	1.9	1.7	1.7	1.9	1.7	-0.4	1.8	2.2	0.9	2.5	1.7
Average weekly red wine intake	2.2	3.2	4.9	0.5	-2.2	-1.5	-0.2	-2.2	-2.1	-2.1	-1.8	-1.9	-2.0	-2.1	-2.0	-2.2	-1.9	-0.6	1.8	-1.2	-2.1
Hair/balding pattern: Pattern 3	2.0	2.9	4.2	1.1	1.8	1.8	-0.9	1.8	1.8	1.8	2.0	1.9	1.9	2.1	1.9	1.5	1.9	1.5	-0.2	2.0	1.8
Happiness	2.0	2.4	12.2	3.0	-0.6	-0.4	1.7	-0.7	-0.3	-0.7	0.2	-0.3	-0.3	-0.6	-0.3	-3.5	-0.4	2.0	3.3	1.3	-0.6
Angina (self-reported)	2.0	2.7	7.5	1.8	1.5	1.2	1.2	1.1	1.8	1.4	1.9	1.6	1.6	1.7	1.5	-0.3	1.4	2.6	0.8	2.7	1.6
Cardiovascular Disease	1.8	5.8	15.2	1.6	-2.9	-2.5	1.6	-2.7	-2.5	-2.6	-1.9	-2.4	-2.4	-2.3	-2.4	-3.9	-2.5	0.0	3.3	-1.1	-2.6
Lung FVC	1.8	9.1	12.9	0.8	3.5	2.8	-2.6	2.7	3.0	3.2	3.4	3.3	3.3	3.5	3.4	3.3	3.2	2.7	-1.4	3.6	3.0
Hearing difficulty/problems with background noise	1.8	2.9	5.0	0.6	1.7	1.5	0.2	1.6	1.7	1.9	2.0	1.9	1.9	2.2	1.9	1.9	1.8	1.6	-0.7	2.0	1.7
Pulse wave reflection index	1.8	2.3	3.4	0.8	1.7	1.4	1.6	1.8	1.6	1.7	1.7	1.6	1.7	1.7	1.7	1.5	1.7	0.8	-0.5	1.2	1.4
Average weekly beer plus cider intake	1.8	2.7	5.0	-1.0	2.0	2.2	-1.8	1.9	1.4	1.8	1.3	1.6	1.6	1.7	1.6	1.3	1.8	-1.0	-2.2	0.0	1.7
Sensitivity / hurt feelings	1.7	3.0	4.8	-1.1	-2.1	-1.8	-1.6	-2.0	-1.9	-1.9	-1.9	-2.2	-1.9	-2.2	-2.0	-0.9	-1.9	-1.3	0.3	-1.2	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	4.5	-1.0	1.7	1.3	0.2	2.0	1.8	1.8	1.5	1.6	1.6	1.6	1.6	1.7	1.5	-0.5	-2.1	0.1	2.0
Heart attack	1.7	2.2	3.5	0.8	1.8	1.9	0.2	1.3	1.7	1.6	1.9	1.6	1.6	1.6	1.6	0.3	1.7	1.1	-0.3	1.7	1.7
Hair/balding pattern: Pattern 4	1.7	4.1	16.1	-3.0	1.8	1.4	-1.9	2.2	1.5	1.7	0.9	1.4	1.3	1.4	1.3	3.4	1.4	-1.9	-4.0	-0.7	2.0
Pulse rate, automated reading	1.7	5.5	10.0	1.4	-2.5	-1.9	1.7	-2.8	-2.5	-2.8	-2.2	-2.6	-2.6	-2.5	-2.6	-2.7	-2.4	0.4	3.2	-1.0	-2.7
Waist Hip Ratio (WHR)	1.6	7.2	12.8	-1.3	-3.0	-2.9	0.1	-2.6	-2.9	-2.9	-3.3	-3.0	-3.1	-2.9	-3.1	-0.8	-3.1	-2.6	0.8	-3.6	-3.0
Angina	1.6	2.1	5.6	1.4	1.4	1.1	1.0	0.9	1.6	1.2	1.7	1.4	1.4	1.6	1.4	-0.2	1.3	2.2	0.5	2.4	1.5
Lung cancer (father)	1.6	1.9	2.9	0.0	1.5	1.4	-1.7	1.2	1.5	1.5	1.5	1.5	1.6	1.6	1.5	1.2	1.4	0.7	-1.0	1.2	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.8	3.3	0.7	1.4	1.5	-0.8	1.2	1.8	1.5	1.5	1.5	1.6	1.6	1.5	0.2	1.6	1.0	-0.4	1.3	1.8
Supplements: Fish oil (including cod liver oil)	1.6	2.1	4.6	-0.1	-1.7	-1.5	0.5	-2.2	-1.6	-1.6	-1.5	-1.4	-1.7	-1.6	-1.6	-1.7	-1.6	-0.6	0.8	-1.0	-1.4
Bipolar Disorder (2018)	1.5	2.4	3.5	-0.1	-1.6	-1.6	1.2	-1.4	-1.6	-1.7	-1.7	-1.6	-1.7	-1.8	-1.6	-1.9	-1.6	-1.1	1.1	-1.6	-1.8
Intelligence (Savage-Jansen 2018)	1.5	4.5	13.9	3.7	1.4	1.9	0.8	1.0	1.7	1.3	2.2	1.7	1.6	1.6	1.6	-2.1	1.8	3.7	2.7	3.0	1.4
Irritable Bowel Disease (IBD)	1.5	3.5	9.1	3.0	2.1	2.6	-0.0	1.4	2.1	1.7	2.0	1.7	1.8	1.5	1.8	-0.8	2.1	2.0	1.6	1.9	1.7
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	8.3	2.8	-0.4	-0.2	1.5	-0.5	-0.2	-0.2	0.6	0.2	0.2	0.1	0.2	-2.3	0.0	2.5	2.9	1.9	-0.4
Maternal smoking around birth	1.5	2.2	4.0	-0.4	1.8	1.7	-1.8	1.5	1.4	1.7	1.5	1.5	1.6	2.0	1.6	1.2	1.6	0.6	-1.5	0.8	1.4
Multivitamins +/- minerals	1.5	1.9	3.7	-0.9	-1.3	-1.2	-1.9	-1.7	-1.6	-1.5	-1.6	-1.5	-1.5	-1.5	-1.5	-0.2	-1.5	-0.9	0.1	-1.4	-1.6
Medication for cholesterol	1.5	2.3	5.3	-0.9	1.6	1.5	-2.3	1.9	1.3	1.7	1.2	1.4	1.5	1.5	1.5	2.2	1.5	-0.4	-1.9	0.1	1.4
Pain experienced in last month	1.5	2.6	5.1	-1.7	-1.4	-1.6	-1.0	-1.4	-1.7	-1.5	-2.0	-1.8	-1.8	-1.7	-1.7	-0.4	-1.7	-2.0	-0.5	-2.3	-1.6
Primary Biliary Cirrhosis	1.4	1.9	3.6	-0.2	-1.5	-1.8	-0.4	-1.9	-1.8	-1.5	-1.4	-1.4	-1.4	-1.4	-1.5	-1.6	-1.6	-0.6	0.8	-0.8	-1.7
Comparative height size at age 10	1.4	7.6	20.9	2.7	-3.1	-2.8	1.1	-3.3	-2.6	-3.0	-2.2	-2.7	-2.9	-3.1	-2.7	-2.9	-2.8	0.8	4.6	-0.3	-2.7
Overall health rating	1.4	2.9	7.5	1.4	1.5	1.5	2.7	1.7	2.1	1.7	1.9	1.8	1.8	1.8	1.8	0.0	1.6	1.5	0.2	1.8	2.0
Age at last live birth	1.4	2.1	5.7	-2.4	-1.1	-1.0	-2.0	-1.0	-1.4	-1.1	-1.6	-1.3	-1.2	-1.2	-1.3	0.5	-1.3	-1.8	-1.5	-1.9	-1.3
Alcohol drinker status: Previous	1.4	1.5	2.4	-0.0	1.2	1.6	-1.3	1.4	1.5	1.1	1.2	1.2	1.2	1.4	1.2	1.2	1.4	1.2	-0.7	1.3	1.4
Heel T-Score	1.3	10.4	20.2	4.4	3.1	3.2	3.0	2.0	3.2	2.9	3.9	3.2	3.2	3.2	3.2	-0.8	3.2	3.9	2.2	4.5	3.1
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.2	3.8	0.5	1.6	1.8	0.2	1.7	1.9	1.6	1.8	1.7	1.6	1.6	1.6	0.4	1.7	0.8	-0.6	1.4	2.0
Medication: Allopurinol	1.3	1.8	2.9	0.2	1.7	1.4	0.2	1.7	1.6	1.6	1.4	1.5	1.5	1.4	1.6	1.1	1.5	0.5	-0.8	1.1	1.7
Ever taken oral contraceptive pill	1.3	1.5	3.0	0.7	-1.3	-1.7	1.7	-1.2	-1.4	-1.2	-0.9	-1.0	-1.1	-1.2	-1.1	-1.7	-1.3	-0.1	1.4	-0.5	-1.2
Unable to work because of sickness or disability	1.3	1.6	4.5	2.1	1.0	1.4	1.8	0.5	1.0	0.8	1.2	1.1	1.0	1.0	1.0	-1.3	1.1	1.8	1.5	1.4	0.8
Supplements: Calcium	1.3	1.4	3.6	0.8	0.9	0.6	-1.9	1.2	1.0	1.2	1.3	1.3	1.4	1.5	1.4	1.0	1.1	1.5	-0.0	1.5	0.8
Medication: Levothyroxine sodium	1.2	2.0	7.4	2.0	-1.1	-0.6	2.3	-1.3	-0.7	-1.1	-0.3	-0.7	-0.8	-1.1	-0.8	-2.4	-0.7	1.5	2.7	1.0	-1.1
Sitting height	1.2	8.8	13.4	0.6	-3.5	-3.7	-1.1	-3.5	-3.6	-3.5	-3.0	-3.1	-3.3	-3.4	-3.3	-2.8	-3.5	-0.1	2.9	-1.1	-3.4
Birth weight of first child	1.2	2.1	4.9	2.2	1.3	1.2	1.3	1.3	1.2	1.4	1.7	1.6	1.7	1.4	1.6	-0.1	1.5	1.8	1.3	1.5	0.9
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.3	-0.9	-1.3	-1.4	-1.5	-1.3	-1.5	-1.3	-1.3	-1.2	-1.3	-1.2	-1.3	-0.4	-1.3	-0.6	0.1	-1.0	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	4.7	0.1	-1.9	-2.2	0.1	-1.6	-1.9	-1.8	-1.7	-1.7	-1.9	-1.8	-1.8	-1.0	-1.9	-0.6	1.2	-1.2	-2.0
Commuting to job workplace: Cycle	1.2	1.5	2.6	1.6	1.4	1.6	-0.5	1.3	1.5	1.2	1.4	1.2	1.4	1.0	1.3	0.0	1.5	0.9	0.6	0.7	1.4
Reaction Time	1.1	2.2	5.3	-2.2	-1.2	-1.6	-0.4	-0.8	-1.2	-1.2	-1.8	-1.4	-1.4	-1.5	-1.4	0.6	-1.5	-2.3	-1.3	-2.1	-1.0
Mean Putamen Volume	1.1	1.2	3.1	0.4	-1.4	-1.1	0.2	-1.0	-1.0	-1.2	-1.0	-1.1	-1.2	-1.4	-1.2	-1.8	-1.2	-0.4	1.2	-0.9	-1.2
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	2.7	1.1	1.3	1.6	-0.6	1.0	1.2	1.2	1.5	1.2	1.3	1.1	1.3	0.9	1.4	1.2	0.1	1.3	1.2
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	7.2	2.3	-0.4	0.5	2.1	-1.0	-0.2	-0.8	0.1	-0.5	-0.5	-0.4	-0.5	-2.1	-0.1	2.3	2.7	1.5	-0.6
Medication: Seretide 50 evohaler	1.1	1.3	4.7	-2.2	-0.6	-0.7	-1.4	-0.0	-0.6	-0.4	-1.0	-0.5	-0.5	-0.7	-0.6	1.0	-0.6	-2.1	-1.8	-1.8	-0.4
Eye problems/disorders: Cataract	1.1	1.2	2.1	0.8	1.0	0.8	0.9	0.9	1.0	1.2	1.4	1.5	1.4	1.4	1.3	0.8	1.2	1.1	-0.1	1.4	1.0
Smoking status: Current	1.1	1.7	5.3	1.6	1.0	1.1	2.0	0.7	0.9	0.9	1.4	1.2	1.3	1.2	1.2	-0.3	1.2	2.3	1.0	1.9	0.7
Hearing aid user	1.1	1.3	4.1	1.1	1.1	1.0	-0.5	0.7	1.0	1.0	1.3	1.2	1.1	1.1	1.2	0.4	1.1	1.8	0.4	2.0	1.0
Ever smoked	1.1	2.0	4.3	-0.3	1.6	1.3	-2.1	1.4	1.4	1.6	1.4	1.5	1.5	1.8	1.6	1.2	1.5	0.8	-1.3	1.2	1.3
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.4	0.9	1.4	1.5	0.5	0.9	1.4	1.2	1.5	1.3	1.3	1.3	1.3	0.1	1.4	1.1	-0.0	1.5	1.4
Smoking Status	1.0	2.3	4.1	0.5	1.7	1.5	-0.1	1.5	1.4	1.7	1.8	1.8	1.8	2.0	1.8	1.0	1.8	1.6	-0.6	1.8	1.3
Systolic blood pressure, automated reading	1.0	2.8	5.8	2.1	1.6	1.5	2.4	1.4	1.9	1.5	1.8	1.6	1.6	1.7	1.6	-0.8	1.6	1.5	0.9	1.8	1.8
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	6.4	0.4	-0.9	-0.6	2.5	-1.2	-0.9	-0.9	-0.7	-0.8	-0.9	-0.9	-0.9	-1.6	-0.8	-0.4	1.0	-0.6	-0.9
Supplements: Zinc	1.0	1.1	2.7	0.9	-1.2	-1.0	1.4	-1.2	-1.0	-1.1	-0.8	-0.9	-0.9	-0.9	-1.0	-1.7	-1.0	0.2	1.6	-0.3	-1.1
Alcohol usually taken with meals	1.0	1.6	4.6	-1.5	-1.1	-0.8	-1.7	-0.9	-1.1	-1.0	-1.4	-1.1	-1.2	-1.3	-1.2	-0.2	-1.1	-2.1	-0.9	-1.8	-1.0
Diabetes (self-reported)	1.0	1.6	9.8	1.7	-0.7	-0.0	3.1	-1.0	-0.5	-0.8	-0.3	-0.6	-0.6	-0.5	-0.5	-2.2	-0.4	1.4	2.1	0.2	-0.8
Gout (self-reported)	1.0	1.4	2.7	0.1	1.3	1.1	0.6	1.7	1.3	1.5	1.3	1.3	1.3	1.5	1.4	0.9	1.3	0.4	-0.9	0.8	1.5
Eye problems/disorders: Glaucoma	1.0	1.2	1.9	-0.0	-1.2	-0.9	0.9	-1.4	-0.9	-1.2	-1.2	-1.2	-1.4	-1.4	-1.3	-1.3	-1.2	-0.6	0.9	-1.2	-1.0
Number of operations (self-reported)	1.0	1.6	3.3	1.5	0.9	0.9	0.7	1.1	1.0	1.1	1.6	1.5	1.4	1.5	1.3	-0.4	1.2	1.7	0.7	1.8	0.9
Average weekly fortified wine intake	0.9	1.0	4.3	1.9	0.1	0.5	-0.1	-0.2	0.4	-0.1	0.5	0.2	0.3	0.2	0.2	-1.3	0.3	2.1	2.0	1.9	0.3
Age when periods started (menarche)	0.9	2.1	8.8	-3.0	0.0	-0.4	-2.2	0.3	-0.4	0.2	-0.6	-0.1	-0.1	0.1	-0.1	1.9	-0.2	-2.7	-2.9	-1.9	0.1
Qualifications: CSEs or equivalent	0.9	1.2	7.0	1.8	0.0	0.3	2.6	-0.4	0.1	-0.1	0.4	0.2	0.1	-0.0	0.1	-2.0	0.1	1.8	1.8	1.3	-0.2
Medication: Cholesterol lowering	0.9	1.3	2.0	-1.0	-1.4	-1.3	0.3	-1.0	-1.3	-1.1	-1.3	-1.4	-1.2	-1.2	-1.2	-0.7	-1.3	-1.2	-0.1	-1.4	-1.2
Age at first live birth	0.9	1.6	5.2	-1.8	-0.7	-0.6	-2.3	-0.6	-1.1	-0.8	-1.2	-1.1	-0.9	-1.2	-1.0	0.9	-0.9	-1.9	-1.2	-1.9	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	3.8	-1.9	-0.3	-0.6	-1.0	0.2	-0.5	-0.2	-0.8	-0.5	-0.4	-0.1	-0.4	1.7	-0.5	-1.6	-1.7	-1.7	-0.5
Verbal and Numeric Reasoning (VNR)	0.8	1.8	6.1	2.3	0.8	1.3	0.8	0.5	1.0	0.7	1.3	1.0	0.8	1.0	0.9	-1.3	1.1	2.5	1.7	2.0	0.9
Severe depression (siblings)	0.8	0.9	1.7	0.6	1.0	0.7	-0.8	0.8	1.1	1.2	1.2	1.3	1.2	1.2	1.2	0.2	1.0	0.8	-0.3	0.8	1.0
Current tobacco smoking	0.8	1.3	3.9	1.5	0.9	0.9	1.8	0.6	0.8	0.8	1.2	1.1	1.1	1.1	1.1	-0.3	1.0	2.0	1.0	1.7	0.6
Relative age voice broke	0.8	1.2	2.9	-0.5	1.3	1.3	-1.7	0.9	1.3	1.0	1.0	1.0	1.0	1.2	0.9	0.8	1.2	0.8	-1.1	1.3	1.3
Had menopause	0.8	0.9	2.6	-0.7	0.9	0.9	-0.2	0.9	1.3	1.0	0.7	1.0	0.9	1.1	0.9	1.6	0.9	0.2	-1.4	0.4	1.3
Mouth/teeth dental problems	0.8	1.2	2.4	-1.0	-1.1	-1.3	-1.6	-1.0	-1.2	-1.1	-1.3	-1.2	-1.2	-1.2	-1.1	0.6	-1.1	-0.7	-0.2	-1.0	-1.2
Impedance of arm (right)	0.8	3.5	7.0	-1.9	-1.8	-2.1	-2.6	-1.8	-1.7	-1.7	-2.2	-1.9	-1.8	-2.0	-1.9	0.2	-2.0	-1.9	-0.6	-2.3	-1.9
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.8	0.7	0.9	0.6	-1.1	1.1	1.2	1.1	1.3	1.3	1.2	1.1	1.2	-0.1	0.9	0.5	-0.1	0.8	1.2
Impedance of arm (left)	0.8	3.6	7.4	-1.9	-1.8	-2.0	-2.7	-1.7	-1.6	-1.8	-2.2	-2.0	-1.9	-2.1	-2.0	0.2	-2.0	-2.1	-0.6	-2.5	-1.8
Standing height	0.8	8.3	13.2	1.4	-3.4	-3.6	-0.3	-3.6	-3.1	-3.3	-2.6	-2.9	-3.1	-3.3	-3.1	-3.3	-3.3	0.1	3.5	-0.9	-3.0
Peak expiratory flow (PEF)	0.8	1.8	4.9	1.1	1.4	1.0	-0.9	1.1	1.4	1.3	1.5	1.6	1.3	1.4	1.4	0.7	1.3	2.2	0.3	2.0	1.3
Medication: Amlodipine	0.8	1.1	2.1	-1.0	-1.1	-1.0	-0.6	-0.7	-1.1	-1.0	-1.3	-1.2	-1.2	-1.1	-1.2	0.1	-1.1	-1.5	-0.2	-1.4	-1.1
Exposure to tobacco smoke outside home	0.8	1.1	2.8	0.6	-1.0	-0.7	1.7	-0.7	-1.1	-1.2	-1.0	-1.1	-1.1	-1.3	-1.2	-0.9	-1.1	-0.5	1.3	-0.8	-1.2
Illnesses of father: High blood pressure	0.8	1.0	2.7	-0.8	-1.2	-1.5	1.6	-0.8	-1.0	-0.9	-1.0	-0.9	-1.0	-0.8	-1.0	-0.3	-1.2	-0.9	-0.0	-0.8	-1.0
Ever had prostate specific antigen (PSA) test	0.8	1.0	1.8	0.7	1.0	0.8	-0.1	0.8	0.9	1.2	1.3	1.2	1.4	1.3	1.3	-0.4	1.2	0.8	-0.1	0.7	0.8
Alzheimer’s Disease (including proxy)	0.7	1.0	3.9	-0.8	-0.9	-1.2	-1.1	-0.2	-1.0	-0.6	-1.0	-0.7	-0.7	-0.9	-0.6	-0.2	-0.8	-2.0	-0.2	-1.7	-0.8
Ulcerative Colitis	0.7	1.0	3.6	1.2	-0.8	-0.6	1.5	-0.7	-0.7	-0.8	-0.7	-0.8	-0.7	-0.8	-0.7	-1.9	-0.7	0.7	1.8	-0.1	-1.0
Height	0.7	14.2	24.6	1.0	-4.6	-4.9	-1.2	-5.0	-4.2	-4.3	-3.6	-3.8	-4.1	-4.4	-4.0	-3.6	-4.4	-0.6	3.8	-1.8	-4.1
Allergy or Eczema	0.7	1.8	8.4	-2.0	0.7	0.4	-0.9	1.1	0.5	0.9	0.1	0.6	0.7	0.9	0.6	2.9	0.5	-2.1	-2.7	-1.1	0.7
Hypothyroidism (self reported)	0.7	1.5	4.5	0.5	-1.2	-1.0	2.1	-1.5	-1.2	-1.4	-0.9	-1.2	-1.3	-1.3	-1.3	-1.5	-1.2	-0.0	1.4	-0.1	-1.3
Respiratory disease	0.7	1.6	2.3	-0.4	1.5	1.5	-0.8	1.4	1.5	1.5	1.2	1.4	1.5	1.4	1.4	1.3	1.5	-0.1	-1.4	0.1	1.5
Type 2 Diabetes (T2D) (2018)	0.7	1.4	4.9	1.4	-1.0	-0.5	2.0	-1.1	-0.8	-1.0	-0.5	-0.9	-1.0	-0.8	-0.9	-2.2	-0.8	0.7	2.1	-0.1	-1.0
Pack years adult smoking proportion	0.7	1.0	3.3	1.7	0.7	1.0	-0.8	0.7	0.9	0.7	0.9	0.8	0.8	0.8	0.8	0.0	0.9	1.8	1.2	1.6	0.7
Stomach or abdominal pain in last month	0.7	0.8	8.3	1.2	0.2	0.1	2.9	0.5	0.2	0.2	0.6	0.5	0.4	0.4	0.4	-1.1	0.2	1.1	0.9	0.7	-0.1
Number of incorrect matches in round	0.7	1.1	4.5	-1.8	0.5	0.2	-0.8	0.4	0.3	0.7	0.2	0.4	0.5	0.3	0.5	1.9	0.4	-2.0	-2.1	-1.1	0.6
Past tobacco smoking	0.7	1.3	3.2	0.6	-1.1	-1.0	1.8	-1.2	-1.0	-1.2	-1.0	-1.1	-1.1	-1.4	-1.2	-1.1	-1.1	-0.5	1.3	-0.9	-1.0
Qualifications: None of the above	0.7	1.4	5.3	-1.2	1.1	1.4	-1.4	1.4	1.1	0.9	0.6	0.6	0.7	0.9	0.7	2.3	1.0	-0.7	-1.9	0.2	1.4
Fluid intelligence score	0.7	1.5	5.6	2.1	0.6	0.8	0.8	0.4	0.9	0.5	1.1	0.8	0.7	0.8	0.7	-1.6	0.9	2.4	1.6	2.1	0.8
Pulse rate	0.7	1.1	3.4	1.1	-0.9	-0.3	0.7	-1.1	-0.9	-1.2	-1.0	-1.0	-1.0	-1.1	-1.1	-1.6	-0.9	0.7	1.9	-0.1	-1.1
Mouth/teeth dental problems: Dentures	0.7	1.2	7.3	1.4	0.6	0.7	2.7	0.3	0.7	0.7	1.1	0.8	0.8	1.0	0.8	-0.1	0.8	1.4	0.9	1.6	0.8
Glaucoma (self-reported)	0.7	0.8	1.6	-0.2	-1.1	-0.7	1.0	-1.3	-0.7	-1.0	-0.9	-1.0	-1.1	-1.1	-1.1	-1.0	-1.0	-0.3	0.5	-0.8	-0.7
Emphysema/chronic bronchitis	0.7	0.7	2.7	0.1	-0.8	-0.9	0.4	-1.1	-1.1	-0.8	-0.8	-0.6	-0.8	-0.7	-0.8	-1.6	-0.9	-0.4	0.7	-0.8	-1.1
Number of full sisters	0.7	0.9	3.2	1.2	0.7	0.5	-1.8	0.9	0.9	0.9	1.1	0.9	1.0	1.0	1.0	0.5	0.8	1.1	0.5	0.9	0.8
Family relationship satisfaction	0.7	0.9	4.0	2.0	0.4	0.1	0.9	0.7	0.6	0.4	0.8	0.5	0.5	0.3	0.6	-1.5	0.4	1.3	1.5	1.0	0.5
Average weekly champagne plus white wine intake	0.7	1.0	3.6	-1.3	0.9	0.7	-0.4	1.4	0.7	1.0	0.4	0.8	0.7	0.9	0.8	1.6	0.8	-1.0	-1.9	-0.5	0.7
Guilty feelings	0.7	1.1	2.6	-0.7	-1.1	-1.3	-1.6	-0.7	-1.1	-0.9	-1.0	-1.0	-1.0	-0.9	-1.0	-1.1	-1.1	-1.1	-0.1	-1.4	-1.0
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.8	1.1	-0.8	-0.5	-1.3	-1.2	-0.8	-1.0	-0.5	-0.9	-0.9	-0.7	-0.8	-0.6	-0.6	0.8	1.7	0.9	-0.9
Medication: Paracetamol	0.7	1.1	4.0	-1.5	0.9	1.2	-0.9	0.8	0.9	0.8	0.5	0.4	0.6	0.7	0.5	1.8	0.7	-1.0	-2.0	0.1	1.1
Irritability	0.7	1.2	4.8	-0.7	1.2	1.0	-2.2	1.0	1.0	1.1	1.0	1.2	1.1	0.9	1.0	0.7	1.0	-0.1	-1.5	0.4	1.1
Ever depressed for a whole week	0.7	0.9	2.9	-1.3	-0.9	-1.1	-0.5	-0.3	-0.7	-0.7	-0.9	-0.7	-0.7	-0.7	-0.8	1.1	-0.9	-1.3	-0.8	-1.7	-0.7
Impedance of whole body	0.7	3.6	7.3	-2.2	-1.7	-2.0	-2.7	-1.7	-1.7	-1.7	-2.2	-1.9	-1.8	-1.9	-1.9	0.4	-1.9	-2.0	-0.8	-2.4	-1.7
Crohns Disease (2012)	0.6	1.0	4.1	2.0	0.6	1.4	-0.4	-0.1	0.5	0.2	0.6	0.2	0.4	0.2	0.3	-1.5	0.7	1.6	1.9	1.2	0.3
LDL Cholesterol	0.6	1.0	1.9	0.2	1.4	1.2	-0.3	1.1	1.1	1.3	1.1	1.3	1.3	1.1	1.3	0.7	1.2	-0.2	-0.5	0.3	1.0
Blood White Count	0.6	4.8	10.2	-0.6	-2.2	-2.3	3.2	-2.0	-2.2	-2.1	-2.2	-2.2	-2.3	-2.3	-2.2	-2.1	-2.4	-1.9	0.8	-2.7	-2.3
Systolic Blood Pressure	0.6	2.9	11.6	3.4	0.9	1.2	2.2	0.6	1.1	0.9	1.5	1.1	1.1	1.2	1.2	-2.4	1.2	2.0	2.5	2.0	1.0
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.7	0.2	0.7	0.9	-1.1	0.3	0.9	0.8	1.0	0.9	0.8	0.9	0.9	0.8	0.9	1.3	-0.4	1.3	0.8
Vitamin and mineral supplements	0.6	0.8	4.5	-0.3	0.7	0.7	2.1	1.1	0.9	0.8	0.7	0.8	0.8	0.7	0.8	0.2	0.8	-0.5	-0.9	0.1	1.1
Waist circumference	0.6	2.2	3.7	-0.3	-1.8	-1.4	1.1	-1.4	-1.5	-1.8	-1.7	-1.8	-1.9	-1.8	-1.8	-1.3	-1.7	-1.0	0.8	-1.0	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.8	0.6	0.9	0.4	0.5	1.3	1.0	1.2	1.2	1.3	1.3	1.1	1.2	0.4	1.0	0.3	-0.2	0.4	1.1
Falls in the last year	0.6	0.8	1.5	0.3	-1.0	-0.8	-0.5	-0.9	-0.9	-1.2	-1.0	-1.2	-1.1	-1.1	-1.1	-0.7	-1.0	0.2	0.9	-0.4	-1.1
Noisy workplace	0.6	0.7	1.5	-0.7	-1.0	-1.0	1.1	-1.0	-1.2	-0.9	-0.8	-0.8	-0.9	-0.8	-0.9	-0.1	-0.9	-0.8	0.0	-0.5	-1.2
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	1.8	-0.1	1.4	1.2	-0.5	0.9	1.2	1.1	1.1	1.2	1.1	1.2	1.1	1.0	1.2	0.6	-0.9	1.0	1.1
Health satisfaction	0.6	0.7	5.0	1.5	0.1	0.7	2.2	0.1	0.6	-0.1	0.3	0.1	0.0	-0.1	0.0	-1.3	0.3	0.9	1.4	0.8	0.4
Eye problems/disorders: None of the above	0.6	0.7	2.9	-1.6	0.4	0.3	-1.6	0.8	0.3	0.3	-0.1	0.0	0.2	0.1	0.1	1.3	0.2	-1.1	-1.7	-0.7	0.4
Mouth/teeth dental problems: Loose teeth	0.6	0.8	6.4	1.4	0.1	0.2	2.5	-0.3	0.1	-0.2	0.2	-0.1	-0.1	-0.2	-0.1	-1.1	-0.0	1.1	1.5	0.7	0.0
Neck or shoulder pain in last month	0.6	0.8	3.8	2.0	0.0	0.7	1.1	-0.2	0.5	0.1	0.6	0.3	0.3	0.1	0.2	-1.5	0.4	1.2	1.8	1.0	0.3
Mood swings	0.6	1.1	5.4	-1.9	0.6	0.5	-1.5	0.6	0.4	0.8	0.4	0.7	0.7	0.3	0.6	1.2	0.5	-1.4	-2.3	-0.9	0.7
Qualifications: nursing, teaching	0.6	1.0	1.8	0.3	-1.1	-1.1	-1.1	-1.1	-1.2	-1.1	-0.9	-1.1	-1.1	-1.2	-1.1	-0.4	-1.1	-0.2	0.9	-0.5	-1.3
Medication: Lisinopril	0.6	0.8	6.9	-1.7	-0.0	-0.3	-0.2	0.2	-0.5	-0.0	-0.3	-0.1	-0.1	0.3	-0.1	2.6	-0.2	-0.8	-1.6	-0.0	-0.2
Risk taking	0.6	0.8	3.7	1.8	0.0	0.1	-0.2	-0.4	0.1	-0.1	0.6	0.3	0.3	0.0	0.3	-1.7	0.2	1.9	1.8	1.1	-0.0
Bipolar Disorder or Schizophrenia	0.5	1.1	4.4	0.7	-0.8	-0.8	2.1	-1.1	-0.9	-0.9	-0.7	-0.9	-0.8	-1.0	-0.8	-1.8	-0.8	-0.2	1.3	-0.8	-1.1
Body Mass Index (BMI) (2010)	0.5	0.7	2.8	1.7	0.6	0.6	1.3	0.6	0.6	0.5	0.9	0.8	0.6	0.4	0.6	-0.7	0.7	0.8	1.1	0.9	0.5
Fasting Glucose	0.5	0.6	2.2	0.6	0.7	0.4	1.0	1.0	1.5	0.8	0.7	0.8	0.6	0.9	0.8	0.5	0.8	0.4	0.1	-0.1	0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.0	0.7	-0.7	-1.4	1.4	-0.6	-0.6	-0.2	-0.3	-1.0	-0.3	-0.4	-0.2	-1.1	-0.8	-0.2	1.1	-0.5	-0.4
Average weekly spirits intake	0.5	0.6	6.8	0.9	-0.1	-0.1	2.6	-0.5	0.0	-0.2	0.2	-0.1	-0.0	-0.1	-0.0	-0.6	-0.0	0.9	0.9	0.4	-0.1
Trunk fat percentage	0.5	2.1	4.4	-1.9	-1.4	-1.2	0.7	-0.9	-1.2	-1.4	-1.7	-1.7	-1.7	-1.6	-1.7	-0.0	-1.6	-2.1	-1.0	-1.8	-1.0
High blood pressure	0.5	1.4	5.2	2.3	0.2	0.4	1.9	0.5	0.7	0.4	0.9	0.7	0.6	0.8	0.6	-1.5	0.5	2.0	1.9	1.8	0.4
Medication: Atenolol	0.5	0.6	2.1	-1.0	0.7	0.8	0.1	0.6	0.8	0.7	0.6	0.7	0.6	0.7	0.7	0.7	0.8	-0.3	-1.4	0.4	1.1
Trunk fat mass	0.5	2.1	3.2	-1.3	-1.6	-1.4	0.9	-1.1	-1.4	-1.6	-1.7	-1.7	-1.8	-1.7	-1.7	-0.6	-1.7	-1.6	-0.3	-1.4	-1.1
Had other major operations	0.5	0.7	2.2	1.4	0.1	-0.2	0.6	-0.0	0.3	0.4	0.9	0.6	0.7	0.7	0.6	-1.0	0.4	1.4	1.1	1.5	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.7	0.4	1.2	1.6	0.7	0.6	0.9	0.9	1.3	1.1	1.0	1.3	1.0	0.5	1.3	1.0	-0.4	1.6	1.2
Allergy	0.5	1.2	5.2	1.8	-0.5	-0.3	1.1	-0.8	-0.3	-0.7	-0.0	-0.6	-0.6	-0.7	-0.5	-1.9	-0.4	1.9	2.3	1.2	-0.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.6	-0.8	0.7	0.8	-0.4	0.8	0.7	0.8	0.5	0.7	0.7	0.7	0.7	1.9	0.7	-0.2	-1.4	0.0	0.8
Neuroticism score	0.5	1.1	2.6	0.0	-1.2	-1.2	-1.2	-0.9	-1.0	-1.1	-0.9	-1.0	-0.9	-1.3	-1.0	-1.6	-1.2	-0.5	0.7	-0.9	-0.9
Depression (self-reported)	0.5	0.6	1.2	1.0	0.7	0.7	-1.1	0.5	0.6	0.9	1.0	1.0	0.9	0.9	1.0	-0.9	0.9	0.5	0.2	0.4	0.4
Worry too long after embarrassment	0.5	0.9	1.3	0.9	0.9	0.9	-0.2	0.7	1.0	0.8	1.2	1.0	1.0	1.0	1.0	-1.1	0.9	1.1	0.3	1.1	1.0
Heart disease (mother)	0.5	0.6	1.5	-0.5	0.8	0.6	-0.5	0.7	0.8	0.9	0.7	0.9	0.7	1.0	0.8	0.9	0.7	0.0	-1.2	0.4	1.0
Chest pain or discomfort	0.5	0.8	2.1	1.5	0.5	0.4	-0.2	0.6	0.6	0.8	1.2	1.0	1.0	1.0	0.9	-0.8	0.8	1.1	0.9	1.1	0.7
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.7	-1.3	-0.5	-0.9	-0.3	-0.9	-0.8	-0.4	-0.5	-0.5	-0.4	-0.5	-0.5	0.8	-0.7	-1.2	-1.0	-1.0	-0.5
Supplements: Vitamin C	0.5	0.6	1.0	0.5	0.9	1.0	-0.3	0.8	0.9	0.8	0.9	0.7	0.8	1.0	0.8	0.6	0.8	0.8	-0.0	0.7	0.6
Hypertension (Self-reported)	0.5	1.3	5.5	2.3	-0.1	0.1	1.8	0.1	0.3	-0.0	0.5	0.2	0.2	0.4	0.2	-1.7	0.2	1.9	2.3	1.6	0.0
Smoking status: Previous	0.5	0.7	4.1	-0.9	0.6	0.5	-2.0	0.7	0.5	0.8	0.5	0.6	0.7	0.9	0.7	1.1	0.7	-0.3	-1.4	0.3	0.7
Handedness (chirality/laterality): Left-handed	0.5	0.6	0.9	0.2	0.8	0.8	0.1	1.0	0.8	1.0	0.9	0.8	0.9	0.7	0.9	0.6	1.0	0.1	-0.3	0.6	0.9
Long-standing illness, disability or infirmity	0.5	0.8	5.0	1.6	0.1	-0.1	2.2	0.3	0.4	0.4	0.8	0.7	0.6	0.4	0.6	-1.5	0.3	0.9	1.2	0.6	0.4
Diabetes diagnosed by doctor	0.5	0.8	5.1	1.5	-0.2	0.3	2.3	-0.5	0.1	-0.2	0.3	-0.1	-0.1	0.0	-0.0	-1.7	0.1	1.3	1.6	0.6	-0.1
Friendships satisfaction	0.5	0.6	3.3	1.5	0.1	0.0	0.9	-0.2	0.2	-0.0	0.4	0.2	0.1	-0.0	0.1	-1.8	0.1	1.0	1.5	0.7	0.1
Mother’s age at death	0.5	0.6	3.1	-1.2	0.1	-0.4	-1.8	0.6	0.1	0.2	-0.3	-0.1	0.0	0.1	0.0	0.9	-0.1	-1.3	-1.3	-1.1	0.1
Commuting to job workplace: Public transport	0.5	0.6	1.8	-0.8	-0.7	-0.4	-1.3	-0.5	-0.6	-0.9	-1.0	-1.0	-0.9	-0.9	-1.0	-0.4	-0.8	-0.8	-0.1	-1.0	-0.6
Medication: Bendroflumethiazide	0.5	0.7	1.2	0.3	-1.0	-0.5	1.1	-0.9	-1.0	-1.1	-0.9	-1.0	-1.0	-0.9	-1.0	-0.6	-0.8	0.3	1.0	0.2	-0.8
Age started oral contraceptive pill	0.5	0.6	1.3	-0.5	0.9	0.9	-0.0	0.6	0.9	0.9	0.7	0.8	0.8	0.8	0.8	1.1	0.8	-0.2	-1.1	0.3	0.9
Pack years of smoking	0.5	0.8	1.9	1.2	0.7	1.1	-1.0	0.8	0.9	0.7	0.7	0.7	0.8	0.7	0.7	0.3	0.8	1.4	0.7	1.2	0.7
Depressed Affect (Nagel 2018)	0.4	0.9	1.8	0.2	-1.0	-1.3	-0.7	-1.4	-1.2	-1.0	-0.6	-0.9	-0.8	-1.1	-0.9	-1.1	-1.1	-0.2	0.8	-0.5	-1.1
Neuroticism (Nagel 2018)	0.4	0.8	2.3	-0.4	-0.9	-1.0	-1.5	-1.2	-0.7	-0.9	-0.6	-0.9	-0.8	-1.0	-0.9	-1.4	-1.0	-0.7	0.2	-0.8	-0.7
Alzheimer’s Disease (in mother)	0.4	0.4	4.0	-0.7	0.1	0.1	-2.0	0.6	0.1	0.1	-0.2	0.1	0.0	-0.0	0.0	0.7	0.0	-1.2	-0.8	-0.8	-0.0
Ulcerative Colitis (UC)	0.4	0.7	1.5	1.2	1.1	1.0	0.5	0.8	1.2	0.9	0.9	0.8	0.9	0.5	0.9	-0.4	1.0	0.8	0.5	0.6	0.9
HbA1C	0.4	0.4	5.0	-0.0	0.1	-0.4	-2.2	0.2	0.3	0.5	0.3	0.2	0.5	0.6	0.5	0.5	0.1	-0.5	-0.3	-0.1	0.3
Schizophrenia (2014)	0.4	1.0	8.0	1.6	0.0	0.3	2.8	-0.3	-0.0	-0.1	0.3	0.1	0.1	-0.2	0.1	-1.7	0.3	1.0	1.6	0.4	-0.3
Blood Eosinophil Count	0.4	3.0	6.6	1.1	2.0	1.2	2.6	1.9	1.8	2.0	2.1	2.1	2.0	1.7	2.1	0.4	1.8	0.8	-0.3	1.0	1.8
Tanning	0.4	4.6	7.6	-0.5	-2.5	-2.5	-0.3	-2.6	-2.6	-2.6	-2.4	-2.6	-2.5	-2.3	-2.4	-1.7	-2.5	0.2	1.4	-1.0	-2.8
Relative age of first facial hair	0.4	0.9	3.3	0.4	1.1	1.8	-1.1	0.5	1.1	0.6	0.9	0.9	0.8	0.7	0.7	-0.3	1.1	1.3	-0.0	1.0	1.0
Taking other prescription medications	0.4	0.6	1.3	1.1	0.4	0.4	0.4	0.5	0.5	0.7	0.9	0.8	0.8	0.8	0.9	-0.7	0.7	1.0	0.6	1.1	0.6
High blood pressure (mother)	0.4	0.6	5.5	0.9	0.1	0.3	2.4	0.1	0.1	0.0	0.3	0.1	0.1	0.4	0.1	-1.1	0.2	1.2	0.9	0.7	-0.1
Impedance of leg (left)	0.4	2.0	3.7	-1.1	-1.5	-1.7	-1.9	-1.8	-1.5	-1.5	-1.6	-1.5	-1.5	-1.4	-1.5	-0.3	-1.6	-0.8	0.0	-1.4	-1.6
Time employed in main current job	0.4	0.4	1.5	-0.8	0.6	0.3	-0.6	0.2	0.4	0.6	0.4	0.7	0.6	0.6	0.6	1.2	0.5	-0.5	-1.2	-0.2	0.5
Number of live births	0.4	0.5	1.7	-0.6	-0.8	-1.0	1.1	-1.3	-0.7	-0.9	-0.7	-0.7	-0.7	-0.4	-0.7	0.5	-0.8	0.3	0.0	0.1	-0.8
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.4	1.3	1.2	1.6	-0.2	0.6	1.0	0.7	1.0	0.8	0.7	0.5	0.8	-0.8	1.1	0.8	0.6	0.4	0.7
Asthma	0.4	0.8	2.5	-1.0	0.7	0.5	-1.0	0.9	0.8	0.8	0.5	0.7	0.8	0.7	0.7	1.2	0.6	-0.9	-1.6	-0.7	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	1.7	0.5	0.7	0.8	0.3	1.3	1.0	1.0	1.0	1.0	1.0	0.9	1.0	-0.1	0.9	0.3	-0.2	0.4	0.9
Medication: Paracetamol	0.4	0.6	2.5	-1.4	0.4	0.7	-1.4	0.4	0.6	0.4	0.2	0.0	0.2	0.3	0.2	1.3	0.3	-1.1	-1.6	0.0	0.7
Birth weight	0.4	0.9	4.5	-1.6	-0.2	-0.5	-0.6	0.3	-0.3	-0.2	-0.7	-0.4	-0.4	-0.4	-0.4	1.7	-0.5	-2.1	-1.4	-1.6	-0.1
Number of children fathered	0.4	0.5	3.4	0.8	0.3	0.1	-1.9	-0.2	0.2	0.4	0.7	0.4	0.6	0.5	0.5	0.3	0.4	1.1	0.6	0.8	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	2.1	1.4	0.0	0.1	0.7	-0.2	0.2	0.2	0.5	0.4	0.5	0.3	0.4	-0.6	0.4	1.2	1.3	0.7	-0.1
Shortness of breath walking on level ground	0.4	0.5	2.8	0.8	-0.8	-0.4	0.6	-0.7	-0.2	-0.6	-0.4	-0.4	-0.6	-0.5	-0.6	-1.7	-0.6	0.5	1.2	0.1	-0.4
Medication for pain relief, constipation, heartburn	0.4	0.7	1.2	-0.1	-0.8	-1.1	0.7	-0.6	-1.0	-0.9	-1.0	-0.8	-0.8	-1.0	-0.8	-0.9	-0.9	-0.4	0.6	-0.9	-1.1
Mean time to correctly identify matches	0.4	0.8	2.9	-1.7	-0.4	-0.6	-0.8	-0.1	-0.2	-0.3	-0.8	-0.5	-0.5	-0.6	-0.5	1.5	-0.6	-1.6	-1.4	-1.2	-0.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.7	-1.2	-0.1	-0.2	0.7	-0.5	-0.5	-0.5	-0.7	-0.7	-0.7	-0.7	-0.7	0.4	-0.4	-1.2	-0.8	-1.3	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	2.1	-1.0	-0.3	-0.6	-1.1	0.1	-0.4	0.1	-0.3	0.1	0.1	-0.1	0.0	0.6	-0.2	-1.4	-1.0	-1.3	-0.3
Medication: Gliclazide	0.4	0.4	4.1	-0.2	0.4	0.6	2.0	0.3	0.5	0.5	0.3	0.4	0.4	0.7	0.4	-0.3	0.5	-0.4	-0.6	-0.7	0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.6	-0.1	0.9	0.8	-1.3	1.0	0.9	0.6	0.5	0.5	0.6	0.5	0.6	1.1	0.6	-0.0	-0.5	0.0	0.8
Medication: Blood pressure	0.4	0.7	4.6	1.2	0.3	0.3	2.1	0.3	0.5	0.4	0.7	0.5	0.5	0.6	0.5	-0.4	0.4	1.1	0.8	1.3	0.5
Fractured/broken bones in last 5 years	0.4	0.5	1.7	-0.6	-0.9	-1.3	-0.3	-0.3	-0.8	-0.7	-0.7	-0.8	-0.6	-0.3	-0.7	0.4	-0.9	-0.3	-0.2	-0.2	-0.8
Myopia	0.4	0.5	2.0	-1.0	-0.6	-0.6	1.2	-0.3	-0.5	-0.5	-0.7	-0.6	-0.6	-0.6	-0.6	-0.7	-0.5	-1.4	-0.6	-0.7	-0.4
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.5	-1.9	-0.4	-0.5	-1.5	-0.7	-0.8	-0.6	-1.0	-0.8	-0.8	-0.9	-0.8	1.2	-0.7	-1.7	-1.4	-1.6	-0.7
Age at First Birth	0.3	0.4	1.7	-0.8	0.2	-0.2	-0.0	0.5	0.1	0.5	-0.0	0.1	0.4	0.0	0.4	1.3	0.1	-1.3	-1.2	-1.1	0.0
Neuroticism (2016)	0.3	0.5	3.0	1.1	-0.5	-0.2	-0.8	-0.6	-0.2	-0.3	0.1	-0.2	-0.1	-0.3	-0.1	-1.7	-0.1	0.4	1.3	0.7	-0.3
Blood Platelet Count	0.3	3.0	37.2	1.6	-1.3	-0.2	6.1	2.0	0.0	-0.2	-0.6	0.2	0.0	0.2	0.0	0.3	-0.1	1.8	1.9	1.2	-0.1
Number of treatments/medications taken	0.3	0.5	1.6	1.3	0.2	0.4	0.5	0.1	0.4	0.4	0.8	0.6	0.6	0.7	0.6	-0.5	0.5	1.1	1.0	1.3	0.4
Ever had hysterectomy (womb removed)	0.3	0.3	0.7	0.0	-0.6	-0.2	0.4	-0.7	-0.5	-0.7	-0.7	-0.8	-0.8	-0.4	-0.7	-0.6	-0.5	-0.1	0.6	-0.1	-0.7
Medication for hormone replacement therapy	0.3	0.3	1.5	0.5	-0.4	-0.3	0.4	-0.5	-0.2	-0.6	-0.3	-0.3	-0.5	-0.5	-0.5	-0.4	-0.4	1.2	0.9	0.5	-0.3
Medication: Co-codamol	0.3	0.3	0.9	-0.3	-0.6	-0.6	0.5	-1.0	-0.6	-0.6	-0.8	-0.4	-0.6	-0.6	-0.6	-0.3	-0.6	-0.2	0.2	-0.5	-0.7
Townsend deprivation index at recruitment	0.3	0.5	1.5	-0.1	-0.8	-0.7	1.2	-0.3	-0.6	-0.7	-0.9	-0.7	-0.6	-0.7	-0.7	-0.3	-0.8	-0.6	0.4	-0.7	-0.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.9	0.1	-0.9	-0.7	-0.0	-0.7	-0.7	-0.7	-0.7	-0.6	-0.7	-0.3	-0.7	0.2	-0.7	0.4	0.6	-0.1	-0.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.9	0.2	-0.4	-0.1	0.8	-0.4	-0.5	-0.6	-0.5	-0.6	-0.5	-0.3	-0.6	-1.0	-0.5	0.1	0.6	-0.0	-0.7
Serious illness, injury or assault to yourself	0.3	0.4	1.6	1.3	-0.1	-0.5	0.7	-0.2	-0.3	0.2	0.6	0.3	0.4	0.4	0.3	-1.0	0.0	0.9	1.1	0.8	-0.1
Hayfever, allergic rhinitis or eczema	0.3	0.7	3.2	-1.4	0.4	0.4	-0.4	0.7	0.2	0.5	0.0	0.4	0.4	0.6	0.4	1.8	0.3	-1.5	-1.8	-0.8	0.3
Supplements: Glucosamine	0.3	0.4	4.3	0.7	-0.2	0.3	-2.1	-0.5	-0.0	-0.3	-0.0	-0.1	-0.2	-0.5	-0.2	-0.3	0.0	1.1	0.9	0.6	-0.1
Chronic bronchitis/emphysema (father)	0.3	0.4	1.4	1.1	0.3	-0.1	-0.2	-0.1	0.3	0.4	0.7	0.5	0.5	0.5	0.5	-0.9	0.3	1.2	0.7	1.0	0.4
Forced vital capacity (FVC)	0.3	1.1	6.4	2.1	0.3	-0.2	-0.6	-0.5	-0.0	0.1	0.7	0.5	0.3	0.3	0.4	-0.6	0.2	2.5	1.9	1.9	-0.1
Financial difficulties in last 2 years	0.3	0.5	1.9	1.0	-0.7	-0.6	1.4	-0.3	-0.3	-0.5	-0.3	-0.3	-0.3	-0.3	-0.4	-0.9	-0.5	0.6	1.3	0.3	-0.5
Weight	0.3	1.6	3.0	0.3	-1.5	-1.3	1.7	-1.2	-1.2	-1.4	-1.1	-1.3	-1.5	-1.4	-1.4	-1.6	-1.4	-0.3	1.2	-0.3	-1.0
Trunk fat-free mass	0.3	1.8	7.3	2.3	-1.0	-1.0	1.8	-1.1	-0.8	-0.9	-0.1	-0.5	-0.7	-0.8	-0.6	-2.5	-0.7	1.5	2.7	1.1	-0.7
Father’s age at death	0.3	0.4	1.6	0.9	-0.6	-0.4	-0.1	-0.9	-0.6	-0.6	-0.1	-0.4	-0.3	-0.2	-0.4	-0.5	-0.4	1.1	1.3	1.0	-0.7
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	6.1	1.9	0.5	0.1	-0.4	-0.3	0.2	0.3	0.8	0.7	0.4	0.5	0.5	-0.5	0.4	2.5	1.6	1.8	0.1
Medication: Lansoprazole	0.3	0.3	1.3	0.6	0.3	0.7	0.5	0.4	0.3	0.4	0.5	0.5	0.4	0.6	0.4	0.7	0.5	0.8	0.4	1.1	0.4
Prospective memory result	0.3	0.3	1.7	-0.2	0.7	0.9	0.4	0.7	0.6	0.4	0.3	0.3	0.4	0.1	0.4	1.3	0.6	-0.2	-0.5	-0.6	0.4
Illnesses of mother	0.3	0.4	2.4	0.7	-0.6	-0.5	1.5	-0.7	-0.4	-0.4	-0.3	-0.3	-0.3	-0.6	-0.3	-1.0	-0.4	0.4	1.1	-0.0	-0.5
Trunk predicted mass	0.3	1.8	6.9	2.2	-1.1	-1.1	1.8	-1.2	-0.9	-1.0	-0.2	-0.5	-0.8	-0.8	-0.7	-2.5	-0.8	1.3	2.6	1.0	-0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.6	1.0	-0.2	0.2	1.1	-0.1	-0.0	-0.2	-0.1	-0.1	-0.0	-0.2	-0.1	-1.6	-0.1	0.2	1.2	-0.3	-0.2
Body fat percentage	0.3	1.3	3.4	-1.8	-1.0	-0.8	0.8	-0.5	-0.7	-1.0	-1.2	-1.2	-1.2	-1.1	-1.2	0.1	-1.1	-1.9	-1.1	-1.4	-0.5
Arm fat-free mass (right)	0.3	1.4	4.3	1.6	-1.0	-0.9	2.1	-0.9	-0.9	-1.0	-0.3	-0.7	-0.9	-0.8	-0.8	-2.1	-0.9	1.0	2.1	0.8	-0.7
Number of full brothers	0.3	0.4	0.9	-0.4	-0.8	-0.7	0.9	-0.7	-0.8	-0.7	-0.6	-0.9	-0.7	-0.6	-0.8	0.1	-0.8	-0.4	0.1	-0.3	-0.6
Whole body fat mass	0.3	1.2	1.8	-1.0	-1.2	-1.1	1.2	-0.7	-1.0	-1.1	-1.2	-1.3	-1.3	-1.3	-1.3	-0.6	-1.3	-1.3	-0.3	-1.0	-0.7
Arm predicted mass (right)	0.3	1.4	4.9	1.6	-1.0	-0.9	1.7	-1.0	-0.9	-1.0	-0.3	-0.7	-0.9	-0.9	-0.8	-2.2	-0.9	1.1	2.2	0.8	-0.7
Knee pain experienced in last month	0.3	0.4	2.1	-0.1	0.7	0.7	1.5	0.6	0.9	0.6	0.5	0.5	0.5	0.5	0.5	0.4	0.5	-0.0	-0.5	0.1	0.8
Illnesses of siblings: Diabetes	0.3	0.4	1.5	0.7	-0.7	-0.1	-0.6	-0.6	-0.6	-0.6	-0.5	-0.5	-0.4	-0.7	-0.5	-0.2	-0.3	0.3	1.2	-0.2	-0.9
Whole body fat-free mass	0.3	1.5	5.0	1.7	-1.1	-1.1	1.8	-1.0	-0.9	-1.0	-0.4	-0.7	-0.9	-0.9	-0.8	-2.2	-0.9	0.9	2.2	0.7	-0.8
Leg fat-free mass (right)	0.3	1.6	3.2	0.7	-1.4	-1.2	1.7	-1.2	-1.4	-1.4	-1.0	-1.3	-1.4	-1.4	-1.3	-1.8	-1.3	-0.0	1.5	-0.1	-1.2
Loneliness, isolation	0.3	0.5	1.3	0.2	-0.8	-0.9	0.0	-0.2	-0.7	-0.7	-0.6	-0.6	-0.7	-1.1	-0.6	-1.0	-0.7	-0.5	0.6	-0.9	-0.6
Whole body water mass	0.3	1.5	5.5	1.8	-1.0	-1.0	2.0	-1.0	-0.9	-0.9	-0.3	-0.6	-0.8	-0.8	-0.7	-2.3	-0.8	1.1	2.3	0.8	-0.7
Leg predicted mass (right)	0.3	1.6	3.0	0.6	-1.4	-1.2	1.7	-1.1	-1.4	-1.4	-1.0	-1.3	-1.4	-1.4	-1.3	-1.7	-1.3	-0.0	1.4	-0.1	-1.2
Basal metabolic rate	0.3	1.7	5.0	1.3	-1.4	-1.3	1.9	-1.3	-1.2	-1.3	-0.7	-1.0	-1.3	-1.2	-1.1	-2.2	-1.2	0.5	2.0	0.3	-1.0
Arm fat-free mass (left)	0.3	1.5	5.3	1.6	-1.0	-0.9	2.3	-1.0	-0.9	-0.9	-0.3	-0.6	-0.8	-0.7	-0.7	-2.1	-0.8	1.1	2.1	0.9	-0.7
Cholesterol lowering medication	0.3	0.4	2.5	0.5	-0.5	-0.7	1.6	-0.7	-0.3	-0.4	-0.0	-0.2	-0.3	-0.4	-0.3	-1.4	-0.4	0.1	0.7	0.3	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	2.2	-0.9	0.0	-0.5	1.5	0.3	-0.1	0.3	0.1	0.2	0.2	0.5	0.2	1.0	-0.1	-0.9	-1.0	-0.7	0.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	3.2	-0.9	-0.1	-0.3	-1.8	0.3	0.3	0.1	-0.1	0.1	-0.0	-0.1	0.0	0.2	-0.1	-0.8	-0.9	-0.5	0.4
Depression (Nagel 2018)	0.2	0.3	0.9	-0.7	0.4	-0.1	-0.0	0.5	0.5	0.6	0.4	0.4	0.5	0.3	0.4	0.7	0.2	-0.8	-1.0	-0.5	0.6
Schizophrenia (2018)	0.2	0.3	2.9	0.9	0.3	0.3	1.7	-0.2	0.2	0.2	0.5	0.2	0.3	0.2	0.3	-0.7	0.3	0.6	0.8	0.3	0.1
Major Depression (MDD)	0.2	0.2	1.0	-0.4	-0.2	-0.4	-0.9	0.1	-0.1	-0.1	-0.3	-0.2	-0.2	-0.2	-0.2	-0.1	-0.2	-1.0	-0.4	-0.9	-0.0
HDL Cholesterol	0.2	0.3	1.8	-1.0	0.0	0.2	-1.3	-0.2	-0.0	0.1	-0.1	-0.1	0.0	-0.2	0.0	0.3	0.1	-1.0	-0.9	-0.5	0.2
Blood Red Count	0.2	2.2	8.4	2.1	0.9	1.4	2.6	1.1	1.0	0.8	1.3	0.9	0.9	1.3	0.9	-0.2	1.0	1.9	1.5	2.9	1.2
Hand grip strength (left)	0.2	0.4	1.2	1.1	0.6	-0.1	-0.7	0.1	0.3	0.6	0.8	0.8	0.6	0.6	0.7	-0.3	0.4	0.9	0.6	0.8	0.2
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.5	0.5	0.5	-0.0	-0.6	0.5	0.6	0.6	0.7	0.7	0.6	0.3	0.6	-0.3	0.4	0.2	0.0	0.4	0.7
Medication: Metformin	0.2	0.2	3.4	-0.0	0.0	-0.2	1.8	0.4	0.4	0.3	0.2	0.3	0.2	0.4	0.3	0.1	0.1	-0.0	-0.2	-0.2	0.3
Impedance of leg (right)	0.2	0.7	3.1	-0.6	-0.8	-1.1	-1.8	-1.2	-0.7	-0.8	-0.9	-0.7	-0.7	-0.7	-0.8	-0.3	-0.9	-0.3	0.1	-0.8	-0.8
Leg fat-free mass (left)	0.2	1.2	3.3	0.8	-1.2	-1.0	1.7	-0.9	-1.0	-1.1	-0.7	-1.0	-1.2	-1.2	-1.0	-1.8	-1.1	0.1	1.4	0.1	-0.9
Hand grip strength (right)	0.2	0.5	2.4	1.5	0.1	-0.2	-0.3	-0.3	-0.1	0.1	0.5	0.4	0.2	0.2	0.3	-1.0	0.1	1.4	1.3	1.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.9	-0.1	0.6	1.0	1.4	0.1	0.3	0.4	0.7	0.5	0.5	0.7	0.5	0.7	0.6	0.3	-0.5	1.0	0.6
Leg predicted mass (left)	0.2	1.1	3.3	0.8	-1.1	-0.9	1.8	-0.9	-1.0	-1.0	-0.6	-0.9	-1.1	-1.1	-0.9	-1.8	-1.0	0.2	1.4	0.2	-0.8
Medication: Simvastatin	0.2	0.4	3.1	0.3	-0.7	-0.7	1.8	-0.4	-0.4	-0.5	-0.2	-0.4	-0.4	-0.4	-0.4	-0.7	-0.5	0.0	0.6	0.1	-0.3
Illnesses of siblings	0.2	0.3	0.7	-0.1	0.8	0.7	0.4	0.4	0.6	0.5	0.5	0.6	0.4	0.6	0.5	0.6	0.6	0.4	-0.5	0.8	0.7
Arm fat percentage (right)	0.2	0.8	2.3	-1.2	-0.7	-0.5	1.4	-0.3	-0.5	-0.7	-0.9	-0.9	-0.9	-0.9	-0.9	-0.1	-0.8	-1.5	-0.8	-1.0	-0.4
Hip circumference	0.2	0.7	2.3	0.3	-0.9	-0.7	0.9	-0.8	-0.7	-0.9	-0.5	-0.9	-0.9	-0.9	-0.8	-1.5	-0.8	0.2	0.9	0.5	-0.5
Alcohol intake versus 10 years previously	0.2	0.3	1.3	1.0	-0.3	0.0	1.1	0.0	0.1	-0.3	-0.1	-0.3	-0.3	-0.2	-0.3	-0.5	-0.2	0.3	1.1	0.5	0.0
Pulse wave Arterial Stiffness index	0.2	0.2	1.5	0.7	0.2	0.3	1.2	0.6	0.4	0.3	0.2	0.2	0.3	0.3	0.2	0.2	0.2	0.2	0.5	-0.1	0.2
Arm fat mass (right)	0.2	0.9	3.0	-0.4	-1.0	-0.8	1.7	-0.7	-0.9	-1.0	-1.0	-1.1	-1.2	-1.1	-1.1	-0.9	-1.1	-0.8	0.2	-0.6	-0.7
Breastfed as a baby	0.2	0.2	1.2	1.1	0.2	0.3	0.6	-0.2	0.3	0.1	0.3	0.3	0.2	-0.2	0.2	-0.4	0.3	0.7	1.0	0.4	0.4
Headache pain in last month	0.2	0.4	2.0	1.3	-0.3	0.3	0.5	-0.6	-0.2	-0.4	0.0	-0.2	-0.2	-0.4	-0.3	-1.1	-0.1	0.5	1.4	0.5	-0.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.3	0.5	-0.8	-0.7	1.2	-0.8	-0.6	-0.7	-0.2	-0.5	-0.5	-0.7	-0.5	-1.1	-0.5	0.1	0.8	0.2	-0.7
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	-0.2	0.5	0.5	-0.5	0.6	0.4	0.7	0.3	0.5	0.6	0.4	0.5	0.3	0.5	-0.8	-0.7	-0.9	0.5
Comparative body size at age 10	0.2	0.6	2.0	-0.9	0.5	0.3	-1.0	0.9	0.5	0.7	0.2	0.6	0.4	0.3	0.5	0.9	0.4	-1.4	-1.4	-0.8	0.7
Wheeze or whistling in the chest in last year	0.2	0.3	1.5	-1.0	0.3	0.3	0.2	0.1	0.2	0.4	0.2	0.3	0.4	0.4	0.3	0.5	0.3	-0.7	-1.2	-0.5	0.5
Pulse wave peak to peak time	0.2	0.3	1.6	-0.4	-0.4	-0.5	-1.2	-0.8	-0.6	-0.4	-0.3	-0.3	-0.5	-0.5	-0.4	-0.4	-0.4	-0.0	-0.1	0.0	-0.4
Alcohol intake frequency.	0.2	0.4	1.1	0.6	0.4	0.7	1.0	1.1	0.8	0.5	0.6	0.5	0.5	0.5	0.5	0.4	0.6	0.6	0.1	1.0	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.8	0.8	-0.1	-0.5	0.3	-0.4	-0.2	-0.0	0.2	0.2	0.0	-0.2	0.1	-0.7	-0.2	0.8	0.9	0.5	-0.2
Medication: Aspirin	0.2	0.3	1.3	0.6	0.2	0.4	-0.9	0.1	0.5	0.3	0.6	0.3	0.4	0.4	0.4	0.2	0.5	1.1	0.4	0.9	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.5	-0.3	0.5	0.4	-0.2	0.3	0.1	0.5	0.4	0.4	0.4	0.6	0.4	0.7	0.4	-0.5	-0.6	-0.0	0.2
Arm fat percentage (left)	0.2	0.8	2.4	-1.1	-0.7	-0.5	1.3	-0.2	-0.5	-0.7	-0.9	-1.0	-1.0	-1.0	-0.9	-0.2	-0.9	-1.6	-0.7	-1.1	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	2.0	-0.4	-0.4	-0.2	-1.4	-0.4	-0.4	-0.5	-0.4	-0.4	-0.5	-0.5	-0.5	-0.4	-0.5	-0.3	-0.1	-0.3	-0.2
Mineral and other dietary supplements	0.2	0.2	0.8	-0.2	0.5	0.5	0.5	0.9	0.5	0.4	0.4	0.3	0.5	0.5	0.4	0.9	0.4	0.1	-0.4	0.3	0.4
Asthma (self-reported)	0.2	0.5	1.6	-0.9	0.5	0.4	-0.9	0.7	0.6	0.6	0.3	0.5	0.7	0.5	0.5	0.8	0.5	-0.8	-1.3	-0.7	0.7
Osteoporosis (self-reported)	0.2	0.2	2.4	-0.7	0.2	0.0	-1.5	0.1	0.3	0.2	-0.2	0.2	0.1	0.1	0.1	0.1	0.1	-0.1	-0.7	0.0	0.3
Medication: Aspirin	0.2	0.3	1.5	0.7	0.2	0.3	-0.9	0.0	0.4	0.2	0.6	0.4	0.4	0.4	0.4	0.2	0.4	1.2	0.5	0.9	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.1	-0.3	-0.6	-1.1	-0.8	-1.0	-0.7	-0.5	-0.5	-0.4	-0.7	-0.6	-0.5	0.3	-0.8	-0.2	0.1	-0.1	-0.6
Arm fat mass (left)	0.2	0.7	2.5	-0.5	-0.9	-0.7	1.6	-0.5	-0.7	-0.9	-0.8	-1.0	-1.0	-1.0	-0.9	-0.7	-0.9	-0.9	-0.1	-0.6	-0.5
Number of self-reported non-cancer illnesses	0.2	0.3	0.9	0.7	0.2	0.3	0.9	0.2	0.4	0.5	0.6	0.6	0.6	0.5	0.6	-0.8	0.5	0.4	0.3	0.7	0.4
Miserableness	0.2	0.3	1.8	0.4	0.4	0.0	-1.3	0.4	0.2	0.4	0.7	0.5	0.6	0.2	0.6	-0.3	0.4	0.7	0.2	0.6	0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.8	-0.3	0.4	-0.2	0.1	0.6	0.3	0.5	0.5	0.7	0.5	0.3	0.5	0.9	0.2	-0.1	-0.6	0.3	0.4
Medication: Atorvastatin	0.2	0.2	2.5	0.2	-0.3	-0.2	0.8	-0.5	-0.2	-0.1	-0.0	-0.0	0.0	-0.2	-0.0	-1.6	-0.1	-0.0	0.4	-0.2	-0.0
Diastolic blood pressure, automated reading	0.2	0.7	2.3	1.5	0.6	0.4	1.1	0.8	0.7	0.6	0.8	0.7	0.7	0.8	0.7	-0.5	0.6	0.9	1.0	1.2	0.8
Basal cell carcinoma (self-reported)	0.2	0.2	1.5	0.4	-0.5	-0.7	1.2	-0.3	-0.3	-0.2	-0.0	-0.2	-0.1	0.1	-0.1	-0.7	-0.3	0.1	0.6	0.1	-0.2
Leg fat mass (left)	0.2	0.7	2.4	-0.6	-1.0	-0.8	1.5	-0.6	-0.8	-0.9	-0.9	-1.0	-1.1	-0.9	-1.0	-0.7	-1.0	-0.7	-0.0	-0.5	-0.6
Arm predicted mass (left)	0.2	1.2	4.3	1.3	-0.9	-0.9	2.1	-0.9	-0.8	-0.9	-0.2	-0.6	-0.8	-0.6	-0.6	-1.8	-0.8	1.0	1.8	0.8	-0.6
Worry (Nagel 2018)	0.1	0.2	1.5	-0.2	-0.2	-0.4	-1.2	-0.2	0.0	-0.1	-0.1	-0.2	-0.1	-0.2	-0.2	-0.9	-0.3	-0.8	-0.2	-1.0	0.1
Bipolar Disorder (2011)	0.1	0.1	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.3
Coronary Artery Disease (CAD)	0.1	0.1	0.5	0.0	-0.5	0.4	0.0	-0.6	-0.2	-0.3	-0.3	-0.2	-0.2	-0.4	-0.3	-0.7	-0.1	-0.2	0.0	-0.4	-0.4
Rheumatoid Arthritis	0.1	0.2	0.5	0.3	0.3	0.2	0.1	0.7	0.2	0.6	0.5	0.5	0.6	0.4	0.6	0.2	0.4	0.0	-0.1	0.2	0.3
BMI	0.1	0.3	0.9	0.2	0.6	0.8	0.8	0.9	0.6	0.6	0.6	0.5	0.5	0.6	0.6	-0.0	0.6	0.1	-0.3	0.5	0.7
Lung FEV1/FVC ratio	0.1	0.5	1.2	0.3	0.7	1.1	0.4	0.5	0.7	0.7	0.8	0.8	0.9	0.9	0.8	1.1	0.9	0.4	-0.3	0.5	0.7
Neuroticism	0.1	0.3	2.1	0.3	-0.4	-0.5	-1.1	-0.5	-0.4	-0.4	-0.1	-0.3	-0.2	-0.5	-0.3	-1.5	-0.4	-0.2	0.5	-0.2	-0.2
Diabetes (mother)	0.1	0.1	0.4	0.1	-0.4	-0.4	0.3	-0.4	-0.3	-0.4	-0.2	-0.3	-0.4	-0.0	-0.3	0.0	-0.3	0.4	0.4	0.7	-0.2
Fed-up feelings	0.1	0.2	0.7	0.7	-0.2	-0.5	-0.5	-0.4	-0.2	-0.2	0.2	-0.1	-0.0	-0.3	-0.1	-0.8	-0.3	0.4	0.7	0.1	-0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.5	0.0	-0.3	-0.6	0.4	-0.6	-0.3	-0.3	-0.3	-0.3	-0.3	-0.5	-0.3	0.2	-0.4	-0.7	0.2	-0.5	-0.3
Body mass index (BMI)	0.1	0.3	4.2	-0.4	-0.1	0.2	2.0	0.3	-0.0	-0.1	-0.1	-0.2	-0.3	-0.1	-0.2	-0.2	-0.1	-0.5	-0.4	-0.0	0.2
Nervous feelings	0.1	0.2	1.6	0.9	0.2	0.3	-0.1	0.0	0.5	0.1	0.2	0.1	0.2	0.1	0.2	-1.3	0.2	0.2	0.7	-0.2	0.3
Worrier / anxious feelings	0.1	0.1	0.8	0.3	0.1	0.4	0.4	0.2	0.2	0.3	0.4	0.2	0.3	0.1	0.3	-0.9	0.2	-0.0	0.2	-0.1	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.9	0.6	-0.3	-0.6	-1.7	-0.9	-0.6	-0.5	-0.2	-0.3	-0.5	-0.5	-0.4	-0.2	-0.5	0.7	0.9	0.4	-0.6
Tense / ‘highly strung’	0.1	0.2	2.0	-0.1	-0.5	-0.7	-1.4	-0.0	-0.1	-0.2	-0.2	-0.2	-0.1	-0.1	-0.2	-0.9	-0.4	-0.3	0.1	-0.6	-0.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.7	-0.3	-0.0	-0.1	-0.2	0.4	-0.0	0.1	0.0	0.1	0.2	-0.2	0.0	-0.4	-0.1	-0.8	-0.4	-0.8	0.0
Blood clot in the leg (DVT)	0.1	0.1	0.9	-0.5	-0.1	-0.3	-0.9	0.3	0.4	0.1	-0.0	0.1	0.0	-0.1	0.1	-0.1	-0.1	-0.5	-0.5	-0.2	0.3
High blood pressure (siblings)	0.1	0.1	1.3	0.3	-0.1	-0.3	1.1	0.3	0.1	0.2	0.3	0.2	0.3	0.2	0.3	-0.6	0.1	-0.0	0.1	-0.0	0.1
Forced vital capacity (FVC), Best measure	0.1	0.5	3.2	0.6	-0.4	-0.9	-1.8	-0.8	-0.7	-0.5	-0.2	-0.3	-0.5	-0.5	-0.4	-0.1	-0.6	0.8	0.9	0.6	-0.6
Leg fat percentage (right)	0.1	0.3	2.0	-0.8	0.2	0.2	1.4	0.5	0.4	0.2	0.0	0.1	-0.0	0.1	0.0	0.2	0.1	-0.9	-0.9	-0.3	0.5
Qualifications: College or University degree	0.1	0.3	1.3	0.9	-0.1	-0.4	-0.4	-0.5	-0.3	-0.2	-0.2	-0.2	-0.3	-0.4	-0.2	-1.1	-0.2	-0.0	1.0	-0.4	-0.5
Medication: Blood pressure	0.1	0.2	1.0	0.8	-0.4	-0.2	0.4	0.0	-0.2	-0.2	-0.1	-0.2	-0.1	-0.1	-0.1	-0.5	-0.1	0.5	1.0	0.5	-0.1
Migraine (self-reported)	0.1	0.1	0.5	0.3	0.4	0.3	-0.7	-0.0	0.4	0.3	0.3	0.2	0.4	0.3	0.4	0.1	0.3	0.6	0.1	0.6	0.3
Medication: Omeprazole	0.1	0.2	1.6	-0.2	0.0	-0.5	1.3	0.1	0.1	0.3	0.3	0.3	0.4	0.6	0.3	0.2	0.1	-0.2	-0.4	-0.1	0.1
Leg fat mass (right)	0.1	0.4	2.7	-0.5	-0.6	-0.5	1.6	-0.2	-0.4	-0.6	-0.5	-0.6	-0.7	-0.6	-0.6	-0.6	-0.6	-0.7	-0.2	-0.3	-0.2
Suffer from ‘nerves’	0.1	0.1	0.5	-0.2	-0.1	-0.4	-0.5	0.6	0.3	0.2	0.1	0.1	0.2	0.2	0.1	0.2	-0.1	-0.7	-0.3	-0.5	0.4
High cholesterol (Self-reported)	0.1	0.1	0.9	-0.3	-0.4	-0.3	0.4	-0.4	-0.4	-0.2	-0.1	-0.2	-0.2	-0.3	-0.2	-0.9	-0.2	-0.4	-0.0	-0.5	-0.1
Alcohol drinker status: Never	0.1	0.1	0.5	0.4	0.0	0.3	0.5	0.4	0.1	0.1	0.2	0.2	0.1	0.1	0.2	0.2	0.2	0.7	0.3	0.1	-0.1
Leg fat percentage (left)	0.1	0.4	1.7	-1.1	-0.3	-0.2	1.3	0.1	-0.2	-0.3	-0.5	-0.5	-0.5	-0.4	-0.5	0.2	-0.4	-1.1	-0.9	-0.6	-0.1
Heart disease (siblings)	0.1	0.2	2.5	0.5	-0.1	-0.2	-1.6	0.1	0.1	0.2	0.4	0.2	0.2	0.1	0.2	-0.2	-0.0	0.1	0.3	-0.2	0.1
Alzheimer’s Disease (in father)	0.0	0.1	0.3	0.1	-0.2	-0.5	0.2	-0.1	-0.2	-0.1	-0.0	-0.1	-0.1	-0.2	-0.1	-0.1	-0.2	-0.6	0.2	-0.3	-0.2
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Chronotype (morning person)	0.0	0.1	1.0	0.5	0.1	0.1	-1.0	0.1	0.2	-0.1	-0.1	-0.1	-0.1	-0.4	-0.1	-0.1	-0.0	0.4	0.5	0.3	0.2
Hair Pigment	0.0	1.3	4.0	-1.1	-0.9	-1.3	-2.0	-0.8	-1.1	-0.9	-1.4	-1.0	-1.1	-1.2	-1.1	0.5	-1.2	-1.0	-0.5	-1.4	-0.9
Ever unenthusiastic/disinterested for a whole week	0.0	0.1	0.2	0.4	-0.2	-0.4	-0.4	0.2	0.1	0.1	0.2	0.2	0.2	0.2	0.2	0.3	-0.1	0.1	0.3	-0.1	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.3	-0.0	-0.1	-0.1	0.5	0.1	0.1	-0.0	-0.1	-0.0	-0.1	-0.0	-0.0	-0.5	-0.1	-0.2	-0.0	-0.2	0.1
Had major operations	0.0	0.1	0.3	0.2	0.2	0.1	-0.6	0.1	0.1	0.1	0.3	0.2	0.2	-0.0	0.1	-0.5	0.1	-0.2	0.1	-0.2	0.2
Leg pain on walking	0.0	0.1	0.3	0.5	0.0	0.3	0.4	0.1	0.2	0.0	0.2	0.1	0.1	0.0	0.0	-0.4	0.1	0.2	0.4	-0.0	0.0
Ever had bowel cancer screening	0.0	0.1	0.6	-0.1	0.1	0.3	0.8	-0.2	0.0	0.0	0.1	0.1	0.1	0.1	0.1	-0.1	0.2	0.0	-0.1	-0.3	-0.1
Wears glasses or contact lenses	0.0	0.0	0.3	-0.2	0.1	0.2	-0.0	-0.1	0.1	-0.1	0.1	-0.0	-0.0	-0.0	0.0	0.5	0.1	0.5	-0.1	0.3	0.0

Hub : Genes

MRPL51

Models

Trait associations