[Hub]/) : Traits : Medication: Cholesterol lowering :

chr19:48,464,978-49,872,085

Best TWAS P=6.89e-08 · Best GWAS P=4.71e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Skin Not Sun Exposed Suprapubic NTN5 0.19 0.07 lasso 5 0.08 2.5e-05 5.3 5.1 2.8e-07 0.93 0.02 0.98 FALSE
2 METSIM Adipose NTN5 0.13 0.10 bslmm 450 0.14 3.2e-20 5.3 5.3 1.5e-07 0.68 0.01 0.99 FALSE
3 The Cancer Genome Atlas Colon Adenocarcinoma FUT2 0.18 0.22 enet 12 0.18 6.8e-11 5.3 -5.3 1.3e-07 -0.95 0.01 0.99 FALSE
4 The Cancer Genome Atlas Brain Lower Grade Glioma NTN5 0.05 0.04 lasso 2 0.02 6.7e-04 5.3 5.3 1.1e-07 0.97 0.01 0.99 FALSE
5 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FUT2 0.05 0.08 lasso 2 0.08 6.7e-09 5.2 -5.3 1.1e-07 -0.96 0.01 0.99 FALSE
6 The Cancer Genome Atlas Pancreatic Adenocarcinoma FUT2 0.08 0.12 lasso 4 0.11 2.5e-05 5.3 -5.3 1.2e-07 -0.92 0.01 0.97 FALSE
7 The Cancer Genome Atlas Rectum Adenocarcinoma FUT2 0.26 0.28 lasso 10 0.22 5.2e-06 5.3 -5.3 1.1e-07 -0.96 0.01 0.98 FALSE
8 The Cancer Genome Atlas Stomach Adenocarcinoma FUT2 0.14 0.16 lasso 8 0.14 4.9e-10 5.3 -5.4 6.9e-08 -0.96 0.01 0.99 TRUE
9 The Cancer Genome Atlas Thyroid Carcinoma NTN5 0.11 0.07 blup 43 0.09 2.6e-09 5.5 5.1 2.8e-07 0.89 0.01 0.99 FALSE