Best TWAS P=3.37e-12 · Best GWAS P=2.83e-62 conditioned to 1.77e-37
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | PVRL2 | 0.09 | 0.05 | blup | 55 | 0.03 | 4.6e-04 | 0.58 | -7.0 | 3.4e-12 | 0.31 | 0.46 | 0.09 | TRUE |
| 4 | YFS | Blood | TOMM40 | 0.04 | 0.00 | bslmm | 371 | 0.01 | 2.6e-04 | -4.92 | 5.9 | 2.8e-09 | -0.08 | 0.05 | 0.02 | TRUE |
| 3 | GTEx | Stomach | BCAM | 0.33 | 0.00 | enet | 3 | 0.01 | 9.6e-02 | 2.12 | -5.9 | 3.9e-09 | 0.27 | 0.07 | 0.08 | TRUE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | APOC2 | 0.18 | 0.12 | enet | 14 | 0.13 | 5.2e-06 | -1.15 | 5.7 | 1.2e-08 | -0.19 | 0.64 | 0.05 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | ZNF229 | 0.28 | 0.09 | enet | 58 | 0.08 | 2.2e-05 | -1.09 | -5.3 | 9.6e-08 | 0.07 | 0.19 | 0.06 | TRUE |
| 1 | GTEx | Esophagus Mucosa | PVRL2 | 0.15 | 0.01 | enet | 10 | 0.02 | 1.7e-02 | -7.26 | 5.4 | 5.9e-08 | -0.16 | 0.14 | 0.04 | FALSE |