Best TWAS P=1.17e-09 · Best GWAS P=7.12e-25 conditioned to 1.98e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Colon Adenocarcinoma | LRPPRC | 0.17 | 0.00 | lasso | 7 | 0.07 | 0.00012 | 2.6 | -5.8 | 6.6e-09 | -0.01 | 0.19 | 0.04 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LRPPRC | 0.10 | 0.02 | blup | 109 | 0.05 | 0.00068 | -1.6 | -6.1 | 1.2e-09 | -0.22 | 0.08 | 0.22 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ABCG5 | 0.05 | 0.04 | blup | 75 | 0.02 | 0.00160 | -3.9 | 5.7 | 9.4e-09 | 0.35 | 0.42 | 0.12 | TRUE |