TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
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Medication: Cholesterol lowering
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chr2:43,791,363-44,450,524
Best TWAS P=1.17e-09 · Best GWAS P=7.12e-25 conditioned to 1.98e-14
43.8M
43.9M
44M
44.1M
44.2M
44.3M
44.4M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
LRPPRC
0.10
0.02
blup
109
0.05
0.00068
-1.6
-6.1
1.2e-09
-0.22
0.08
0.22
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
ABCG5
0.05
0.04
blup
75
0.02
0.00160
-3.9
5.7
9.4e-09
0.35
0.42
0.12
TRUE
1
The Cancer Genome Atlas
Colon Adenocarcinoma
LRPPRC
0.17
0.00
lasso
7
0.07
0.00012
2.6
-5.8
6.6e-09
-0.01
0.19
0.04
FALSE