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chr2:26,883,355-28,414,302

Best TWAS P=3.72e-15 · Best GWAS P=4.58e-15 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FNDC4	0.13	0.06	lasso	2	0.05	1.1e-03	7.8	-7.9	3.7e-15	-0.99	0.00	0.96	TRUE
2	GTEx	Esophagus Muscularis	NRBP1	0.07	0.04	lasso	6	0.04	1.3e-03	-5.0	6.5	9.9e-11	0.82	0.01	0.97	FALSE
4	GTEx	Testis	NRBP1	0.16	0.09	lasso	3	0.06	1.8e-03	-5.0	6.1	9.5e-10	0.80	0.03	0.96	FALSE
5	GTEx	Testis	AC074117.10	0.14	0.08	lasso	6	0.12	4.5e-06	-4.0	6.1	1.2e-09	0.85	0.05	0.94	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	GPN1	0.06	0.02	lasso	6	0.02	7.2e-05	6.5	6.0	1.6e-09	0.54	0.00	0.98	FALSE
3	GTEx	Ovary	AC074117.10	0.16	0.04	enet	9	0.05	2.0e-02	-3.8	5.8	5.9e-09	0.77	0.04	0.80	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	FNDC4	0.24	0.09	enet	9	0.17	1.9e-16	-3.0	-5.7	1.1e-08	-0.70	0.41	0.59	FALSE
6	GTEx	Thyroid	FNDC4	0.24	0.10	enet	23	0.16	2.2e-12	-2.6	-5.6	2.8e-08	-0.69	0.67	0.33	FALSE
1	GTEx	Esophagus Mucosa	AC074117.10	0.12	0.14	lasso	8	0.14	2.1e-09	-5.0	5.2	1.9e-07	0.74	0.94	0.06	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	GCKR	0.18	0.08	enet	5	0.13	1.7e-12	-2.6	-5.2	2.4e-07	-0.64	0.91	0.09	FALSE
9	The Cancer Genome Atlas	Skin Cutaneous Melanoma	SLC4A1AP	0.17	0.05	blup	26	0.08	4.4e-03	6.5	-5.1	2.8e-07	-0.47	0.01	0.72	FALSE