Best TWAS P=1.81e-07 · Best GWAS P=4.4e-07 conditioned to 0.378
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DNAJC11 | 0.03 | 0.03 | lasso | 5 | 0.04 | 3.1e-05 | -5.1 | -5.2 | 1.8e-07 | 0.89 | 0.02 | 0.97 | TRUE |
| 2 | GTEx | Testis | THAP3 | 0.22 | 0.19 | lasso | 5 | 0.22 | 3.1e-10 | -4.7 | -5.2 | 2.4e-07 | 0.89 | 0.02 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DNAJC11 | 0.02 | 0.00 | blup | 74 | 0.01 | 9.1e-03 | -4.7 | -5.2 | 2.3e-07 | 0.90 | 0.02 | 0.64 | FALSE |