TWAS hub - DNAJC11

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0340	0.0140	0.0018	0.030	0.020	0.028	0.018	0.036	0.00012	0.0014	0.00019	0.0027	3.1e-05
2	TCGA	Brain Lower Grade Glioma	0.0181	0.0118	0.0097	0.003	0.014	0.002	NA	0.005	0.12000	0.0091	0.20000	NA	7.3e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Blood pressure	18.5	32.6	32.9	5.7	5.7
Medication for cholesterol, blood pressure or diabetes	16.3	27.0	27.2	-5.2	-5.2
Lung FEV1/FVC ratio	15.1	76.4	78.9	8.9	8.6
Medication: Cholesterol lowering	14.1	22.0	22.8	4.8	4.6
High blood pressure (mother)	12.8	18.0	19.6	4.4	4.0
Heel T-Score	12.6	99.9	104.0	9.8	10.2
Leg fat percentage (right)	11.5	41.6	42.4	6.5	6.4
Medication: Simvastatin	11.3	16.6	17.7	4.2	3.9
Leg fat percentage (left)	10.6	38.4	39.1	6.3	6.1
Comparative body size at age 10	9.7	26.9	29.7	4.9	5.5
Major Depression (MDD)	9.5	11.5	11.6	-3.4	-3.4
Cardiovascular Disease	9.5	31.5	34.1	5.8	5.4
Had menopause	9.4	11.7	13.2	-3.6	-3.2
High blood pressure	8.8	24.5	24.8	5.0	4.9
Hypertension (Self-reported)	8.5	23.7	24.0	4.9	4.8
Leg fat mass (right)	8.4	32.5	33.4	5.8	5.6
Heel bone mineral density (BMD) T-score, automated (left)	8.2	18.6	18.6	4.3	4.3
Leg fat mass (left)	8.1	31.7	32.5	5.7	5.6
Vascular/heart problems diagnosed by doctor	8.0	21.9	22.7	-4.8	-4.6
Systolic Blood Pressure	7.6	37.9	39.1	6.1	6.2
Heel bone mineral density (BMD) T-score, automated (right)	7.0	16.0	16.5	3.9	4.1
Diabetes (self-reported)	6.8	10.5	12.3	3.5	3.0
Number of live births	6.8	9.6	12.0	2.7	3.5
Waist circumference	6.6	24.3	26.4	5.1	4.7
Medication: Atenolol	6.4	8.0	8.6	2.9	2.7
Arm fat percentage (left)	6.4	25.6	26.1	5.1	5.0
Vitamin and mineral supplements	6.2	8.5	9.1	3.0	2.8
Multivitamins +/- minerals	6.2	7.9	8.8	-3.0	-2.6
Body fat percentage	6.2	24.4	25.7	5.1	4.8
Schizophrenia (2018)	5.8	12.1	12.7	-3.4	-3.6
Arm fat percentage (right)	5.8	23.0	24.0	4.9	4.7
Diabetes diagnosed by doctor	5.8	9.5	11.0	3.3	2.8
BMI	5.7	33.1	34.0	5.8	5.7
Whole body fat mass	5.7	23.8	25.3	5.0	4.7
Arm fat mass (left)	5.7	23.6	24.7	5.0	4.7
Medication: Ramipril	5.6	7.2	7.4	2.6	2.7
Body mass index (BMI)	5.5	23.5	24.1	4.9	4.8
Medication: Bendroflumethiazide	5.3	8.0	8.6	2.7	2.9
Diabetes (mother)	5.2	6.6	7.3	2.7	2.4
Systolic blood pressure, automated reading	5.1	14.8	15.8	3.7	4.0
Arm fat mass (right)	5.1	21.2	22.5	4.7	4.4
Supplements: Fish oil (including cod liver oil)	5.1	6.6	7.7	-2.8	-2.3
Depression (Nagel 2018)	5.0	7.5	7.7	-2.7	-2.8
Illnesses of siblings: Diabetes	5.0	6.2	6.7	2.6	2.4
Schizophrenia (2014)	4.8	10.5	10.7	-3.3	-3.2
Illnesses of siblings	4.8	6.7	8.2	-2.9	-2.3
Medication: Blood pressure	4.8	9.0	9.3	3.0	3.0
Trunk fat percentage	4.7	18.7	19.4	4.4	4.2
Trunk fat mass	4.7	20.2	21.4	4.6	4.4
Hearing difficulty/problems with background noise	4.7	7.5	8.0	-2.6	-2.8
High cholesterol (Self-reported)	4.7	8.3	9.5	3.1	2.7
Bipolar Disorder or Schizophrenia	4.6	11.3	12.2	-3.5	-3.2
HbA1C	4.5	5.0	6.3	2.5	1.9
Mineral and other dietary supplements	4.5	6.0	7.5	2.7	2.1
Myopia	4.4	6.4	6.8	-2.5	-2.6
Medication for hormone replacement therapy	4.2	4.7	4.9	-2.1	-2.2
Illnesses of father: High blood pressure	4.0	4.9	5.2	2.1	2.3
Medication: Metformin	3.9	5.5	5.7	2.4	2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.9	5.1	6.0	-2.0	-2.5
Medication: Gliclazide	3.9	4.4	4.6	2.1	2.1
Hearing aid user	3.9	4.4	4.9	2.0	2.2
Guilty feelings	3.8	5.7	6.1	-2.3	-2.5
Chronic bronchitis/emphysema (mother)	3.7	4.3	4.7	-2.2	-2.0
Verbal and Numeric Reasoning (VNR)	3.6	8.7	8.7	2.9	2.9
Type 2 Diabetes (T2D) (2018)	3.6	6.7	7.3	2.7	2.5
Noisy workplace	3.6	4.5	4.6	-2.1	-2.1
Wears glasses or contact lenses	3.6	4.2	4.3	-2.0	-2.1
Body Mass Index (BMI) (2010)	3.5	4.8	5.3	2.3	2.1
Ever highly irritable/argumentative for 2 days	3.5	4.2	4.7	-1.9	-2.2
Number of self-reported non-cancer illnesses	3.5	6.1	6.5	2.5	2.4
Type 2 Diabetes (T2D) (2012)	3.4	4.0	4.5	1.8	2.1
Hip circumference	3.4	14.8	15.4	3.9	3.8
Ever used hormone-replacement therapy (HRT)	3.2	4.0	4.2	-2.1	-2.0
Supplements: Zinc	3.2	3.5	4.6	-2.1	-1.5
Frequency of tenseness / restlessness in last 2 weeks	3.2	5.0	6.0	-2.0	-2.4
Medication: Lisinopril	3.2	4.2	5.2	2.3	1.8
Had other major operations	3.1	3.7	4.5	-1.7	-2.1
Risk taking	3.1	4.6	4.7	-2.2	-2.1
Mean Putamen Volume	3.0	3.4	4.2	-2.1	-1.6
Heart disease (siblings)	3.0	3.7	4.5	2.1	1.7
Frequency of depressed mood in last 2 weeks	2.9	4.0	4.0	-2.0	-2.0
Diverticular disease/diverticulitis (self-reported)	2.9	3.4	3.7	1.9	1.8
Schizophrenia vs Biploar Disorder	2.8	3.7	4.7	-1.6	-2.2
Weight	2.8	13.6	15.1	3.9	3.5
Age started oral contraceptive pill	2.8	3.5	4.6	1.6	2.1
Medication: Amlodipine	2.7	3.8	3.9	2.0	1.9
Angina (self-reported)	2.7	3.5	3.7	1.9	1.8
Commuting to job workplace: Walk	2.7	2.9	3.4	-1.6	-1.8
Birth weight of first child	2.6	4.7	4.8	-2.2	-2.1
Alcohol intake frequency.	2.6	6.1	7.1	2.2	2.7
Cholesterol lowering medication	2.6	3.9	4.8	2.2	1.7
Ever unenthusiastic/disinterested for a whole week	2.5	3.0	3.1	-1.7	-1.8
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.2	3.6	-1.7	-1.9
Alcohol intake versus 10 years previously	2.4	3.5	4.6	-1.6	-2.1
Father’s age at death	2.4	3.2	3.3	-1.8	-1.8
Fluid intelligence score	2.2	4.6	5.3	2.0	2.3
Number of full brothers	2.2	2.7	3.1	1.8	1.5
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.6	2.7	-1.6	-1.6
Intelligence (Savage-Jansen 2018)	2.1	6.6	7.5	2.4	2.7
High blood pressure (siblings)	2.1	3.0	3.8	1.9	1.5
Medication: Ibuprofen	2.1	2.5	2.6	-1.6	-1.6
Average weekly beer plus cider intake	2.1	3.0	3.6	-1.9	-1.6
Bipolar Disorder (2011)	2.0	2.0	2.0	-1.4	-1.4
Triglycerides	2.0	3.3	3.9	2.0	1.6
Chronotype (morning person)	2.0	4.7	6.0	1.9	2.4
Angina	2.0	2.7	2.8	1.7	1.6
Ever depressed for a whole week	2.0	2.5	2.8	-1.7	-1.5
Birth weight	1.9	4.0	4.2	-2.0	-2.0
Osteoarthritis (self-reported)	1.9	2.5	2.8	-1.7	-1.5
Peak expiratory flow (PEF)	1.8	4.2	4.6	2.0	2.1
Medication: Paracetamol	1.8	3.0	3.1	-1.7	-1.8
Qualifications: None of the above	1.7	3.6	4.0	2.0	1.8
Hair/balding pattern: Pattern 4	1.7	4.0	4.2	2.0	2.0
Supplements: Vitamin C	1.7	2.0	2.3	-1.5	-1.3
HDL Cholesterol	1.6	2.7	3.7	-1.9	-1.3
Allergy or Eczema	1.6	4.1	4.2	-2.0	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	2.2	-1.4	-1.5
Sitting height	1.6	11.4	13.4	-3.1	-3.7
Qualifications: College or University degree	1.6	5.1	6.1	-2.5	-2.0
Lupus	1.5	2.2	2.4	1.4	1.6
Ever had hysterectomy (womb removed)	1.5	1.7	1.8	-1.3	-1.3
Illnesses of mother	1.5	1.9	2.0	-1.4	-1.4
Ulcerative Colitis	1.4	2.1	2.4	-1.3	-1.6
Average weekly spirits intake	1.4	1.7	2.8	-0.8	-1.7
Average weekly fortified wine intake	1.4	1.6	2.0	1.4	1.1
Chest pain or discomfort	1.4	2.0	2.3	1.5	1.3
Family relationship satisfaction	1.4	1.7	2.4	-1.0	-1.6
Smoking status: Previous	1.4	2.1	2.7	-1.2	-1.6
Smoking Status	1.3	3.0	3.7	-1.5	-1.9
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	2.6	-0.9	-1.6
Eye problems/disorders: None of the above	1.3	1.5	2.4	1.5	0.8
Migraine (self-reported)	1.3	1.6	2.1	-1.5	-1.1
Overall health rating	1.3	2.9	3.4	1.8	1.5
Supplements: Calcium	1.3	1.4	2.1	-1.4	-0.9
Past tobacco smoking	1.2	2.2	3.1	1.1	1.8
Loud music exposure frequency	1.2	1.3	1.4	-1.1	-1.2
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	2.1	1.5	1.3
Friendships satisfaction	1.2	1.5	1.8	-1.1	-1.3
Medication: Paracetamol	1.2	1.9	2.0	-1.3	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	1.8	-0.9	-1.3
Illnesses of father: Heart disease	1.1	1.6	1.9	1.4	1.1
Average weekly red wine intake	1.1	1.7	1.7	-1.3	-1.3
Fractured/broken bones in last 5 years	1.1	1.4	1.5	-1.2	-1.2
Alzheimer’s Disease (including proxy)	1.0	1.5	1.6	-1.3	-1.1
Blood Red Count	1.0	9.9	11.6	-2.9	-3.4
Exposure to tobacco smoke at home	1.0	1.1	1.1	1.1	1.1
Glaucoma (self-reported)	1.0	1.1	1.2	-1.1	-1.0
Pulse wave peak to peak time	1.0	1.2	1.8	-1.3	-0.8
Rheumatoid Arthritis	0.9	1.3	1.4	1.2	1.1
Hearing difficulty/problems: Yes	0.9	1.3	1.5	-1.1	-1.2
Relative age of first facial hair	0.9	1.8	2.1	-1.3	-1.4
Financial difficulties in last 2 years	0.9	1.2	1.4	1.2	1.0
Heart attack	0.9	1.2	1.4	1.2	1.0
Headache pain in last month	0.9	1.6	2.2	-0.9	-1.5
Shortness of breath walking on level ground	0.9	1.1	1.2	1.1	1.0
Breast cancer (self-reported)	0.9	1.1	1.2	-0.9	-1.1
Miserableness	0.9	1.6	2.0	-1.0	-1.4
Medication: Atorvastatin	0.9	1.2	1.2	1.1	1.1
Arm fat-free mass (left)	0.9	4.4	5.2	2.3	1.9
Bipolar Disorder (2018)	0.8	1.2	1.9	-1.4	-0.7
Irritable Bowel Disease (IBD)	0.8	1.9	2.4	-1.6	-1.2
Lung cancer (father)	0.8	0.9	1.0	-0.9	-1.0
Pulse wave Arterial Stiffness index	0.8	1.0	1.6	1.3	0.6
Pulse wave reflection index	0.8	1.0	1.5	1.2	0.7
Ever taken oral contraceptive pill	0.8	0.9	1.0	0.9	1.0
Mother’s age at death	0.8	1.0	1.5	-1.2	-0.8
Financial situation satisfaction	0.8	1.0	1.2	-0.8	-1.1
Alcohol drinker status: Never	0.8	1.0	1.5	0.7	1.2
Basal metabolic rate	0.8	4.2	5.1	2.2	1.8
Arm predicted mass (left)	0.8	4.1	5.0	2.2	1.8
Alzheimer’s Disease (in mother)	0.7	0.8	0.9	-0.9	-0.9
Waist Hip Ratio (WHR)	0.7	3.2	4.5	2.1	1.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.4	-0.3	-1.2
Mood swings	0.7	1.3	1.7	-1.0	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	1.7	1.3	1.1
Eye problems/disorders: Glaucoma	0.7	0.8	0.9	-1.0	-0.8
Diastolic blood pressure, automated reading	0.7	2.2	2.6	1.3	1.6
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.2	1.1	0.8
Ulcerative Colitis (UC)	0.6	1.2	1.2	-1.1	-1.1
Reaction Time	0.6	1.2	1.2	-1.1	-1.1
Crohns Disease (2012)	0.6	0.9	1.0	-1.0	-0.9
Leg fat-free mass (left)	0.6	3.3	4.1	2.0	1.6
Hayfever, allergic rhinitis or eczema	0.6	1.2	1.5	-1.0	-1.2
Leg predicted mass (left)	0.6	3.1	3.8	1.9	1.6
Pain all over the body in last month	0.6	0.6	0.7	-0.9	-0.7
Arm predicted mass (right)	0.6	3.3	3.7	1.9	1.7
Neuroticism (Nagel 2018)	0.5	1.1	1.6	-0.8	-1.3
Worry (Nagel 2018)	0.5	1.1	1.4	-0.9	-1.2
Crohns Disease (2017)	0.5	1.0	1.6	-1.3	-0.7
Primary Biliary Cirrhosis	0.5	0.8	0.8	0.9	0.8
Height	0.5	9.5	12.3	-2.6	-3.5
Neuroticism	0.5	1.1	1.5	-0.9	-1.2
Pack years adult smoking proportion	0.5	0.8	1.1	1.0	0.7
Medication: Levothyroxine sodium	0.5	0.9	1.0	-0.9	-1.0
Forced vital capacity (FVC)	0.5	2.0	2.5	-1.3	-1.6
Allergy	0.5	1.1	1.4	0.8	1.2
Impedance of arm (right)	0.5	2.5	2.7	-1.5	-1.6
Falls in the last year	0.5	0.6	0.9	-0.9	-0.7
Depression (self-reported)	0.5	0.6	0.7	0.7	0.8
Standing height	0.5	4.5	5.6	-1.9	-2.4
Arm fat-free mass (right)	0.5	2.5	3.1	1.8	1.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	0.7	-0.8	-0.8
Pulse rate, automated reading	0.5	1.8	2.0	1.4	1.2
Age at last live birth	0.5	0.7	1.2	0.5	1.1
Long-standing illness, disability or infirmity	0.5	0.7	0.8	0.9	0.8
Medication for cholesterol	0.5	0.8	1.0	-1.0	-0.8
Commuting to job workplace: Public transport	0.5	0.6	0.7	0.7	0.9
Ever smoked	0.5	0.8	1.4	-0.5	-1.2
Alcohol drinker status: Previous	0.5	0.6	0.9	0.5	1.0
Age at First Birth	0.4	0.6	0.8	-0.7	-0.9
Coronary Artery Disease (CAD)	0.4	0.5	0.6	0.7	0.7
Neuroticism (2016)	0.4	0.5	0.7	0.8	0.6
Hand grip strength (left)	0.4	1.1	1.2	-1.0	-1.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	0.4	-0.7	-0.6
Maternal smoking around birth	0.4	0.6	0.6	-0.8	-0.8
Qualifications: CSEs or equivalent	0.4	0.6	0.7	0.8	0.7
Number of incorrect matches in round	0.4	0.6	0.7	-0.8	-0.8
Worrier / anxious feelings	0.4	0.7	0.9	-0.7	-0.9
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	1.6	1.3	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.8	0.9	0.3
Impedance of arm (left)	0.4	1.7	1.8	-1.3	-1.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.7	0.8	0.6
Blood clot in the leg (DVT)	0.4	0.5	0.9	-0.9	-0.4
Gout (self-reported)	0.4	0.5	0.7	-0.6	-0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	0.9	-0.8	-1.0
Forced vital capacity (FVC), Best measure	0.4	1.6	2.1	-1.1	-1.4
Emphysema/chronic bronchitis	0.4	0.4	0.5	0.7	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	0.5	0.7	0.6
Number of full sisters	0.4	0.4	0.8	0.3	0.9
Leg pain on walking	0.4	0.5	0.6	-0.6	-0.8
Back pain experienced in last month	0.4	0.5	1.0	-0.3	-1.0
Number of operations (self-reported)	0.4	0.6	0.7	-0.8	-0.7
Pain experienced in last month	0.4	0.7	1.3	0.1	1.2
Basal cell carcinoma (self-reported)	0.4	0.5	0.7	-0.5	-0.8
Fasting Glucose	0.3	0.4	0.5	0.6	0.7
Blood Platelet Count	0.3	3.4	5.4	2.3	1.2
Number of treatments/medications taken	0.3	0.6	0.8	0.6	0.9
Hand grip strength (right)	0.3	0.7	0.7	-0.9	-0.8
Age when periods started (menarche)	0.3	0.8	0.8	-0.9	-0.9
Serious illness, injury or assault to yourself	0.3	0.4	0.4	-0.6	-0.6
Chronic bronchitis/emphysema (father)	0.3	0.3	0.3	-0.5	-0.6
Alcohol usually taken with meals	0.3	0.5	0.5	0.7	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.9	-0.4	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	1.4	1.2	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.6	-0.5	-0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.6	-0.8	-0.5
Age at first live birth	0.3	0.5	0.9	-0.9	-0.2
Health satisfaction	0.3	0.4	0.6	-0.5	-0.8
Mean time to correctly identify matches	0.3	0.5	0.6	-0.7	-0.8
Had major operations	0.3	0.3	0.5	-0.3	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.5	-0.5	-0.7
Whole body fat-free mass	0.3	1.9	2.5	1.6	1.1
Leg fat-free mass (right)	0.3	1.4	1.9	1.4	1.0
Asthma (self-reported)	0.3	0.6	0.8	0.9	0.6
Medication: Aspirin	0.3	0.4	0.5	0.7	0.5
Whole body water mass	0.3	1.7	2.3	1.5	1.1
Leg predicted mass (right)	0.3	1.6	2.0	1.4	1.0
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.4	0.6	0.5
Unable to work because of sickness or disability	0.3	0.4	0.6	0.4	0.8
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.7	-0.9	-0.2
Pack years of smoking	0.3	0.4	0.6	0.8	0.5
Ovarian Cancer	0.2	0.3	0.3	-0.6	-0.4
Prostate Cancer	0.2	0.3	0.5	-0.3	-0.7
Hair Pigment	0.2	6.2	6.7	-2.6	-2.4
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.3	-0.6	-0.4
Medication: Co-codamol	0.2	0.2	0.4	0.6	0.3
Severe depression (siblings)	0.2	0.3	0.4	-0.4	-0.6
Townsend deprivation index at recruitment	0.2	0.2	0.3	-0.6	-0.4
Relative age voice broke	0.2	0.3	0.6	-0.1	-0.8
Hair/balding pattern: Pattern 2	0.2	0.2	0.3	-0.6	-0.3
Neuroticism score	0.2	0.5	0.8	-0.5	-0.9
Asthma	0.2	0.4	0.6	0.8	0.4
Breastfed as a baby	0.2	0.2	0.5	0.0	0.7
Tense / ‘highly strung’	0.2	0.3	0.5	-0.4	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.4	0.7	0.4	0.8
Medication: Allopurinol	0.2	0.3	0.4	-0.4	-0.6
Medication: Omeprazole	0.2	0.2	0.3	0.6	-0.3
Medication: Seretide 50 evohaler	0.2	0.2	0.2	0.4	0.5
Suffer from ‘nerves’	0.2	0.3	0.4	-0.4	-0.7
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.2	0.4	0.4
Ever had bowel cancer screening	0.2	0.2	0.4	0.6	0.2
Irritability	0.2	0.3	0.5	0.2	-0.7
Impedance of whole body	0.2	0.9	1.0	-1.0	-0.9
Depressed Affect (Nagel 2018)	0.1	0.2	0.3	-0.3	-0.6
Breast Cancer	0.1	0.3	0.5	0.7	0.1
LDL Cholesterol	0.1	0.1	0.2	0.4	0.1
Respiratory disease	0.1	0.3	0.4	-0.5	-0.6
Tanning	0.1	0.7	0.9	-0.9	-0.7
Diabetes (father)	0.1	0.1	0.1	0.2	-0.3
Fed-up feelings	0.1	0.2	0.3	0.5	0.3
Taking other prescription medications	0.1	0.1	0.1	0.4	0.3
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	0.3	0.2
Stomach or abdominal pain in last month	0.1	0.1	0.1	-0.1	-0.3
Supplements: Glucosamine	0.1	0.2	0.4	-0.6	-0.0
Mouth/teeth dental problems	0.1	0.1	0.1	0.3	0.3
Trunk fat-free mass	0.1	0.8	1.2	1.1	0.7
Time employed in main current job	0.1	0.1	0.1	-0.3	-0.3
Pulse rate	0.1	0.1	0.2	0.1	0.5
Happiness	0.1	0.2	0.3	-0.1	-0.6
Prospective memory result	0.1	0.1	0.2	0.0	-0.4
Trunk predicted mass	0.1	0.7	1.1	1.0	0.6
Length of working week for main job	0.1	0.1	0.1	0.3	0.2
Exposure to tobacco smoke outside home	0.1	0.1	0.3	-0.1	-0.5
Neck or shoulder pain in last month	0.1	0.1	0.2	0.1	-0.5
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	-0.2	0.4
Medication: Aspirin	0.1	0.1	0.2	0.4	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	0.1	0.5
Qualifications: nursing, teaching	0.1	0.2	0.3	-0.6	-0.3
Eye problems/disorders: Cataract	0.1	0.1	0.3	0.1	0.5
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	-0.2	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.1	-0.0	0.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	-0.4	-0.3
Average weekly champagne plus white wine intake	0.1	0.1	0.3	0.0	-0.5
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	-0.5	0.2
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.2	-0.2	-0.5
Commuting to job workplace: Cycle	0.1	0.2	0.2	0.4	0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.3	0.2	-0.5
Alzheimer’s Disease (in father)	0.0	0.0	0.1	-0.3	-0.1
Blood Eosinophil Count	0.0	0.3	0.6	0.8	0.3
Blood White Count	0.0	0.0	0.1	0.3	0.1
Hypothyroidism (self reported)	0.0	0.0	0.0	0.1	-0.0
Lung FVC	0.0	0.2	0.4	0.2	0.6
Sensitivity / hurt feelings	0.0	0.1	0.1	0.1	-0.4
Impedance of leg (right)	0.0	0.2	0.2	0.4	0.5
Current tobacco smoking	0.0	0.0	0.0	0.1	-0.1
Impedance of leg (left)	0.0	0.0	0.0	0.1	0.2
Nervous feelings	0.0	0.0	0.1	0.1	-0.3
Hair/balding pattern: Pattern 3	0.0	0.0	0.1	0.1	-0.3
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.1	0.3	0.3
Mouth/teeth dental problems: Dentures	0.0	0.0	0.0	-0.2	0.1
Medication: Lansoprazole	0.0	0.0	0.0	0.0	0.2
Worry too long after embarrassment	0.0	0.1	0.2	-0.0	-0.4
Wheeze or whistling in the chest in last year	0.0	0.1	0.1	0.2	-0.3
Number of children fathered	0.0	0.0	0.0	-0.2	-0.2
Heart disease (mother)	0.0	0.0	0.1	-0.3	-0.1
Comparative height size at age 10	0.0	0.0	0.0	0.2	-0.0
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.0	0.1	-0.0
Knee pain experienced in last month	0.0	0.0	0.1	-0.3	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.0	0.0	0.2	-0.0
Loneliness, isolation	0.0	0.0	0.0	-0.0	0.2
Osteoporosis (self-reported)	0.0	0.0	0.0	-0.2	-0.1
Smoking status: Current	0.0	0.0	0.1	-0.0	-0.3

Hub : Genes

DNAJC11

Models

Trait associations