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chr1:11,060,075-12,600,396

Best TWAS P=6.94e-11 · Best GWAS P=9.61e-11 conditioned to 0.0176

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Skin Not Sun Exposed Suprapubic CLCN6 0.12 0.03 lasso 3 0.04 3.3e-03 3.8 5.5 3.2e-08 0.83 0.02 0.94 FALSE
2 METSIM Adipose DRAXIN 0.09 0.01 enet 21 0.04 1.6e-06 1.3 -5.1 2.9e-07 -0.51 0.03 0.92 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma CLCN6 0.06 0.06 blup 104 0.06 5.0e-12 4.9 6.5 6.9e-11 0.75 0.25 0.75 TRUE
4 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CLCN6 0.04 0.06 lasso 2 0.05 1.1e-06 4.9 5.5 4.0e-08 0.69 0.10 0.89 FALSE
5 The Cancer Genome Atlas Lung Adenocarcinoma CLCN6 0.06 0.04 blup 104 0.04 5.2e-06 6.5 6.5 9.7e-11 0.91 0.01 0.99 FALSE
6 The Cancer Genome Atlas Prostate Adenocarcinoma CLCN6 0.10 0.07 blup 104 0.07 3.9e-08 4.6 5.9 4.4e-09 0.59 0.20 0.79 FALSE
7 The Cancer Genome Atlas Stomach Adenocarcinoma CLCN6 0.07 0.04 blup 104 0.05 2.4e-04 6.3 5.6 2.1e-08 0.94 0.01 0.98 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma CLCN6 0.08 0.02 blup 104 0.05 2.5e-05 3.9 5.7 1.1e-08 0.64 0.15 0.84 FALSE