Best TWAS P=1.7e-07 · Best GWAS P=3.66e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | CDC16 | 0.14 | 0.09 | lasso | 3 | 0.10 | 2.9e-04 | 5.1 | 5.1 | 3.0e-07 | 0.99 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | CDC16 | 0.17 | 0.13 | lasso | 6 | 0.15 | 4.6e-11 | 5.0 | 5.2 | 1.7e-07 | 0.98 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Colon Sigmoid | UPF3A | 0.15 | 0.10 | lasso | 8 | 0.08 | 8.3e-04 | 5.0 | 5.2 | 2.2e-07 | 0.97 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | CDC16 | 0.11 | 0.09 | blup | 49 | 0.09 | 1.8e-04 | 4.9 | 5.2 | 2.3e-07 | 0.98 | 0.01 | 0.97 | FALSE |