Best TWAS P=3.23e-12 · Best GWAS P=1.36e-18 conditioned to 1.72e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATXN2 | 0.02 | 0.03 | enet | 8 | 0.02 | 4.8e-04 | -4.3 | 6.4 | 1.5e-10 | 0.56 | 0.28 | 0.62 | FALSE |
| 2 | GTEx | Artery Tibial | HECTD4 | 0.05 | 0.02 | lasso | 3 | 0.01 | 3.1e-02 | 6.1 | 5.5 | 3.4e-08 | 0.78 | 0.01 | 0.92 | FALSE |
| 3 | YFS | Blood | SH2B3 | 0.05 | 0.01 | enet | 22 | 0.02 | 3.3e-07 | -4.7 | 7.0 | 3.2e-12 | 0.64 | 0.73 | 0.27 | TRUE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ERP29 | 0.11 | 0.03 | blup | 25 | 0.05 | 5.0e-03 | -3.7 | -5.3 | 1.3e-07 | -0.60 | 0.01 | 0.75 | FALSE |