[Hub]/) : Traits : Medication: Blood pressure :

chr15:90,712,555-92,135,418

Best TWAS P=2.15e-21 · Best GWAS P=6.77e-17 conditioned to 0.948

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum FES 0.21 0.09 lasso 5 0.05 1.3e-03 8.4 -8.3 1.4e-16 -0.99 0.00 1.00 FALSE
2 GTEx Artery Tibial FES 0.16 0.04 lasso 5 0.05 4.8e-05 8.0 -8.3 1.1e-16 -0.89 0.00 1.00 FALSE
3 GTEx Cells Transformed fibroblasts FES 0.28 0.17 enet 21 0.20 2.8e-15 8.4 -8.8 1.5e-18 -0.92 0.00 1.00 FALSE
4 GTEx Lung FES 0.24 0.07 lasso 6 0.05 5.1e-05 8.0 -8.8 1.9e-18 -0.90 0.00 1.00 FALSE
5 GTEx Skin Sun Exposed Lower leg FES 0.09 0.04 lasso 5 0.04 1.4e-04 8.4 -7.3 2.5e-13 -0.91 0.00 0.99 FALSE
6 GTEx Thyroid FES 0.33 0.19 lasso 6 0.18 4.3e-14 7.9 -8.2 2.3e-16 -0.95 0.01 0.99 FALSE
7 METSIM Adipose FES 0.08 0.06 lasso 3 0.05 6.8e-08 7.7 -8.1 7.5e-16 -0.88 0.04 0.96 FALSE
8 YFS Blood FES 0.31 0.11 enet 77 0.22 1.2e-68 8.4 -6.8 8.8e-12 -0.61 0.00 1.00 FALSE
9 YFS Blood FURIN 0.11 0.03 enet 37 0.06 8.3e-19 -4.8 -6.1 1.4e-09 -0.48 0.79 0.21 FALSE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma FES 0.06 0.05 blup 46 0.06 1.9e-05 7.7 -7.3 2.1e-13 -0.74 0.02 0.96 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma FES 0.06 0.05 blup 46 0.07 7.4e-14 8.4 -9.5 2.1e-21 -0.88 0.00 1.00 TRUE
12 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FES 0.06 0.02 blup 46 0.02 2.4e-02 8.4 -8.3 1.1e-16 -0.81 0.00 0.90 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma FES 0.08 0.07 blup 46 0.06 3.4e-04 7.0 -7.9 2.4e-15 -0.84 0.04 0.88 FALSE
14 The Cancer Genome Atlas Glioblastoma Multiforme FES 0.12 0.06 enet 6 0.06 5.7e-03 7.6 -7.4 1.7e-13 -0.80 0.01 0.80 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FES 0.06 0.03 blup 46 0.05 5.6e-06 7.6 -7.8 4.4e-15 -0.78 0.01 0.99 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FES 0.10 0.07 enet 5 0.05 2.8e-06 7.7 -7.3 2.8e-13 -0.70 0.21 0.79 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma FES 0.05 0.04 lasso 2 0.04 2.2e-05 8.4 -8.7 3.1e-18 -0.95 0.00 1.00 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FES 0.08 0.07 enet 7 0.08 4.2e-09 8.4 -8.7 2.2e-18 -0.93 0.00 1.00 FALSE
19 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FES 0.13 0.16 lasso 2 0.14 6.1e-10 8.4 -8.3 9.6e-17 -0.99 0.00 1.00 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma FES 0.12 0.09 lasso 5 0.08 4.1e-09 8.4 -8.9 5.5e-19 -0.95 0.00 1.00 FALSE
21 The Cancer Genome Atlas Stomach Adenocarcinoma FES 0.04 0.01 blup 46 0.02 1.7e-02 7.7 -8.4 6.4e-17 -0.75 0.01 0.56 FALSE
22 The Cancer Genome Atlas Testicular Germ Cell Tumors FES 0.32 0.26 lasso 2 0.25 2.0e-09 8.2 -8.2 2.6e-16 -0.96 0.00 1.00 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma FES 0.30 0.30 lasso 7 0.32 1.3e-31 8.2 -8.8 1.6e-18 -0.95 0.00 1.00 FALSE