Best TWAS P=2.3e-09 · Best GWAS P=1.04e-08 conditioned to 0.118
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PDXK | 0.14 | 0.11 | lasso | 3 | 0.12 | 6.2e-07 | -5.3 | -5.3 | 8.9e-08 | 0.97 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | HSF2BP | 0.30 | 0.27 | lasso | 3 | 0.30 | 1.4e-10 | -5.2 | -5.2 | 2.2e-07 | 0.84 | 0.07 | 0.93 | FALSE |
| 3 | GTEx | Esophagus Mucosa | PDXK | 0.29 | 0.18 | enet | 12 | 0.24 | 4.1e-16 | -5.3 | -5.5 | 3.7e-08 | 0.84 | 0.04 | 0.96 | FALSE |
| 4 | GTEx | Muscle Skeletal | PDXK | 0.06 | 0.02 | lasso | 3 | 0.01 | 8.3e-02 | -5.5 | -5.3 | 1.5e-07 | 0.80 | 0.03 | 0.90 | FALSE |
| 5 | GTEx | Testis | HSF2BP | 0.22 | 0.27 | lasso | 3 | 0.27 | 2.8e-12 | -5.5 | -5.4 | 7.7e-08 | 0.86 | 0.04 | 0.96 | FALSE |
| 6 | GTEx | Vagina | PDXK | 0.23 | 0.19 | lasso | 1 | 0.23 | 5.2e-06 | -5.3 | -5.3 | 1.1e-07 | 0.90 | 0.05 | 0.93 | FALSE |
| 7 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | HSF2BP | 0.16 | -0.01 | blup | 62 | 0.02 | 4.7e-02 | 3.2 | 5.6 | 1.9e-08 | -0.87 | 0.01 | 0.19 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | HSF2BP | 0.04 | 0.02 | lasso | 3 | 0.02 | 1.1e-02 | -5.5 | -6.0 | 2.3e-09 | 0.80 | 0.02 | 0.68 | TRUE |