TWAS hub - PDXK

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1350	0.0440	2.4e-05	0.107	NA	0.100	NA	0.116	1.8e-06	NA	3.8e-06	NA	6.2e-07
2	GTEx	Cells Transformed fibroblasts	0.1130	0.0470	8.8e-03	-0.002	NA	0.037	NA	0.004	4.5e-01	NA	8.7e-04	NA	1.4e-01
3	GTEx	Esophagus Mucosa	0.2870	0.0640	3.6e-12	0.176	NA	0.240	NA	0.235	7.1e-12	NA	4.2e-16	NA	8.4e-16
4	GTEx	Heart Left Ventricle	0.2068	0.0615	4.0e-04	-0.003	NA	0.032	NA	0.002	5.4e-01	NA	8.0e-03	NA	2.3e-01
5	GTEx	Liver	0.1770	0.0760	6.1e-03	0.041	NA	0.034	NA	0.051	2.7e-02	NA	4.1e-02	NA	1.5e-02
6	GTEx	Lung	0.1387	0.0529	3.8e-04	0.041	NA	0.042	NA	0.045	4.0e-04	NA	3.5e-04	NA	2.3e-04
7	GTEx	Muscle Skeletal	0.0623	0.0275	2.6e-03	0.018	NA	0.002	NA	0.006	6.3e-03	NA	1.7e-01	NA	8.3e-02
8	GTEx	Vagina	0.2310	0.0780	7.2e-04	0.193	NA	0.205	NA	0.230	3.4e-05	NA	1.9e-05	NA	5.2e-06
9	NTR	Blood	0.0741	0.0209	4.6e-08	0.054	0.028	0.048	0.048	0.052	7.3e-17	2.2e-09	3.1e-15	3.8e-15	2.2e-16
10	TCGA	Lung Squamous Cell Carcinoma	0.0414	0.0214	8.6e-03	-0.002	0.010	0.000	NA	-0.001	8.3e-01	2.4e-02	3.1e-01	NA	3.9e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Medication: Blood pressure	8.9	15.6	30.3	-5.3	1.1	-5.5	-1.3	-4.5	-3.7	-5.3	-5.3	0.2	2.0
Medication for cholesterol, blood pressure or diabetes	6.8	11.3	21.2	4.6	-0.2	4.5	-0.4	4.2	2.8	4.6	4.4	-0.5	-2.3
Vascular/heart problems diagnosed by doctor	6.4	17.4	36.5	6.0	-1.1	6.0	1.0	4.4	4.2	4.7	5.5	0.4	-3.2
Had major operations	5.6	6.6	13.4	-3.7	1.0	-2.2	-0.0	-3.6	-3.0	-2.9	-3.3	0.6	2.2
Medication: Blood pressure	5.4	10.2	22.6	-4.4	0.8	-4.8	-1.0	-3.2	-3.1	-3.5	-4.1	-1.0	2.8
Hayfever/allergic rhinitis (self-reported)	5.3	7.0	15.7	3.4	-0.8	2.6	-0.2	3.5	2.2	4.0	3.9	-1.6	-0.9
Alcohol intake versus 10 years previously	5.3	7.9	18.0	-3.8	0.0	-4.2	1.7	-3.5	-3.2	-2.9	-3.3	-0.8	1.1
Breast cancer (self-reported)	5.3	6.3	9.7	2.9	-1.6	2.8	2.7	2.8	2.5	2.7	3.1	-0.5	-2.4
Medication: Lisinopril	5.0	6.5	12.6	-3.2	1.1	-3.5	-1.0	-2.6	-2.9	-3.0	-2.8	-1.5	2.4
High blood pressure	4.9	13.7	29.1	-5.4	0.4	-5.1	-1.0	-3.9	-3.7	-4.3	-5.3	-0.3	2.3
High blood pressure (siblings)	4.8	7.0	15.3	-3.2	0.0	-3.9	-0.0	-3.0	-3.1	-3.5	-3.2	-0.5	1.6
Systolic Blood Pressure	4.4	21.9	41.7	-6.1	1.0	-6.5	-0.6	-4.9	-5.5	-5.6	-5.8	-3.0	3.3
Reason for reducing amount of alcohol drunk: Health precaution	4.4	5.2	9.3	-2.6	-0.5	-2.0	0.8	-2.7	-3.0	-2.2	-2.5	-3.1	1.7
Hypertension (Self-reported)	4.4	12.3	26.8	-5.2	0.2	-4.8	-1.4	-3.7	-3.2	-4.2	-5.0	0.2	1.8
Cardiovascular Disease	4.3	14.1	27.4	-5.2	1.6	-5.1	-0.5	-3.4	-4.1	-4.8	-5.2	-1.0	2.2
Coronary Artery Disease (CAD)	3.9	4.7	9.9	-3.0	-0.5	-2.1	-0.0	-2.5	-2.2	-2.8	-3.1	-0.8	1.9
Mouth/teeth dental problems: Dentures	3.9	6.6	12.1	-2.9	2.0	-3.5	1.6	-2.3	-2.1	-3.1	-3.1	-1.4	2.8
Body Mass Index (BMI) (2010)	3.8	5.2	10.4	-3.2	-0.1	-2.5	-0.2	-3.0	-1.9	-1.9	-2.7	-1.6	3.0
Illnesses of mother	3.8	4.7	6.7	2.5	1.7	2.5	-1.5	2.6	1.2	2.2	2.5	2.0	-2.6
Friendships satisfaction	3.7	4.6	10.2	2.4	-1.2	2.7	0.6	2.3	1.5	3.2	2.9	0.8	-2.2
Medication for cholesterol	3.5	5.3	11.6	3.0	-0.7	3.4	0.3	2.6	2.6	2.2	2.5	1.5	-2.3
Medication: Atenolol	3.3	4.2	7.4	-2.4	1.6	-2.7	-0.4	-2.2	-2.6	-2.4	-2.5	0.3	1.6
Medication: Ramipril	3.3	4.2	9.7	-2.8	-0.9	-3.1	0.9	-2.5	-1.7	-2.4	-2.1	-0.3	2.1
Hayfever, allergic rhinitis or eczema	3.2	7.0	16.9	3.8	0.6	2.1	-1.0	3.7	2.6	3.4	4.1	-0.4	-0.9
Smoking status: Previous	3.2	4.8	9.4	-2.6	3.1	-2.1	0.6	-1.8	-2.9	-2.1	-2.9	1.4	0.9
Breast Cancer	3.1	7.6	12.7	-3.3	1.4	-2.5	0.8	-3.3	-3.3	-3.4	-3.6	-0.6	3.1
Allergy or Eczema	3.0	8.0	17.5	4.1	0.2	2.6	-0.4	3.7	3.0	3.6	4.2	-0.4	-1.6
Medication: Cholesterol lowering	3.0	4.7	8.1	-2.9	-0.4	-2.8	1.6	-2.8	-1.4	-2.5	-2.6	-0.4	2.4
Supplements: Calcium	3.0	3.3	4.8	1.9	-0.7	2.2	2.1	1.7	2.1	2.1	2.1	1.3	-1.5
Happiness	2.9	3.6	7.3	2.4	0.0	2.2	-1.2	1.9	1.8	2.3	2.7	1.6	-1.4
Medication: Bendroflumethiazide	2.9	4.4	8.5	-2.6	1.2	-2.9	-2.3	-2.4	-1.8	-1.6	-2.2	-0.3	2.4
Past tobacco smoking	2.8	5.2	9.6	2.8	-2.7	2.0	-0.6	2.1	3.0	2.6	3.1	-0.7	-1.4
Time employed in main current job	2.8	3.2	6.9	-2.6	0.8	-1.8	-0.7	-2.4	-1.8	-1.6	-2.1	-0.6	2.0
Angina (self-reported)	2.6	3.4	7.7	-2.3	0.9	-2.8	1.7	-1.8	-1.2	-2.2	-2.0	-0.6	1.9
Angina	2.5	3.3	8.3	-2.3	0.9	-2.9	1.4	-1.7	-1.2	-2.1	-2.0	-0.7	2.0
Mean time to correctly identify matches	2.5	4.7	9.0	3.0	-1.2	2.5	1.1	2.8	2.3	2.7	2.7	-0.1	-1.2
Smoking Status	2.4	5.7	10.6	-3.1	0.9	-2.5	1.7	-2.5	-2.5	-2.6	-3.2	-1.2	2.5
Medication for hormone replacement therapy	2.4	2.6	6.8	-1.6	0.2	-1.7	1.0	-2.0	-1.7	-0.9	-1.2	-2.0	2.6
Qualifications: A levels/AS levels or equivalent	2.4	5.2	11.4	3.0	-0.7	2.5	-0.5	2.4	2.6	1.7	3.4	1.6	-2.5
Medication: Aspirin	2.4	3.1	6.2	-2.2	1.4	-2.5	-0.0	-1.4	-1.8	-2.5	-2.2	-0.1	1.5
Myopia	2.4	3.5	11.5	2.3	-3.4	1.3	1.6	1.9	1.8	1.3	2.4	-0.5	-0.6
Blood Eosinophil Count	2.3	17.4	31.9	-4.9	2.4	-5.4	2.9	-4.2	-3.9	-3.8	-4.8	-2.3	5.6
Illnesses of siblings	2.3	3.2	6.2	2.2	0.5	2.5	-0.0	2.1	1.3	2.3	2.3	1.1	-1.8
Medication: Lansoprazole	2.2	2.5	6.1	-1.6	2.2	-2.2	-0.5	-1.3	-0.6	-1.6	-1.2	0.5	2.5
Deep venous thrombosis (DVT) (self-reported)	2.2	2.9	5.9	-1.8	0.7	-1.8	-1.4	-1.6	-2.4	-2.3	-1.9	1.0	1.1
Medication: Metformin	2.1	3.0	7.0	-2.1	1.4	-2.2	0.8	-1.5	-2.0	-2.6	-2.1	-0.5	0.3
Diabetes (self-reported)	2.1	3.2	6.9	-2.5	0.8	-2.3	1.4	-1.7	-2.2	-1.8	-2.6	0.5	-0.2
Reaction Time	2.0	3.9	8.6	2.9	-1.0	2.0	0.9	2.8	1.8	2.0	2.5	-0.0	-1.6
HbA1C	2.0	2.2	3.5	1.4	-1.6	1.7	-1.0	1.7	1.5	1.8	1.1	-0.9	-1.9
Number of full brothers	2.0	2.5	4.6	2.1	0.0	1.7	-0.4	2.0	1.6	1.8	2.2	1.5	0.7
Medication: Aspirin	2.0	2.6	5.4	-1.9	1.6	-2.3	0.2	-1.1	-1.7	-2.1	-1.9	-0.6	1.3
Commuting to job workplace: Walk	2.0	2.1	3.4	1.6	-1.3	1.8	1.2	1.5	1.0	1.3	1.3	-1.6	-1.7
Ever had prostate specific antigen (PSA) test	2.0	2.3	4.7	-2.2	0.1	-1.9	1.0	-1.8	-1.2	-1.5	-1.8	-0.4	1.7
Vitamin and mineral supplements	1.9	2.6	6.9	-1.3	2.6	-1.8	-1.0	-1.1	-2.4	-1.8	-1.1	-1.1	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.1	10.9	3.1	-2.3	3.3	0.7	2.8	1.8	2.7	2.5	-0.3	-3.2
Medication: Amlodipine	1.9	2.7	5.8	-2.3	-0.9	-2.4	-0.4	-1.9	-1.7	-1.8	-2.2	0.3	0.0
Comparative body size at age 10	1.9	5.3	11.0	-3.3	1.9	-1.2	-2.7	-3.0	-2.3	-1.8	-3.2	0.7	1.4
Heart disease (mother)	1.9	2.3	8.1	-1.9	-0.8	-1.1	-0.7	-1.9	-0.6	-1.3	-1.8	0.3	2.8
Basal cell carcinoma (self-reported)	1.9	2.3	7.0	1.4	-1.0	1.5	-1.6	1.3	2.7	1.6	1.7	-0.9	-0.2
Bipolar Disorder (2018)	1.8	2.8	5.7	1.7	-0.3	2.1	-0.9	2.4	1.9	2.3	1.4	1.1	-1.5
Crohns Disease (2012)	1.8	2.9	7.9	-2.4	-0.2	-1.8	0.3	-1.7	-1.4	-2.8	-2.4	-0.4	0.9
Qualifications: CSEs or equivalent	1.8	2.4	6.3	2.5	-1.0	1.4	0.4	2.0	2.1	1.5	1.9	0.2	0.1
Allergy	1.8	4.2	9.5	-2.7	-0.5	-1.4	1.3	-2.9	-1.9	-2.9	-3.1	0.5	-0.5
Number of children fathered	1.8	2.0	3.6	-1.3	-1.0	-1.4	1.0	-1.6	-1.3	-1.7	-1.9	-1.7	1.0
Neck or shoulder pain in last month	1.8	2.5	5.7	-1.8	0.8	-2.4	-0.9	-1.9	-2.1	-0.7	-1.3	0.1	2.1
Ever smoked	1.8	3.1	5.3	-2.2	1.5	-1.9	0.1	-1.7	-2.3	-2.2	-2.3	0.1	1.6
Mean Putamen Volume	1.7	1.9	4.4	1.6	0.4	2.1	-0.2	1.5	2.0	1.6	1.4	1.2	-0.3
Blood Red Count	1.7	16.6	32.1	-4.9	2.1	-5.7	-0.1	-5.1	-4.7	-5.1	-4.8	-1.2	2.6
Heart attack	1.7	2.2	4.8	-1.9	0.7	-2.1	-0.1	-1.7	-0.7	-2.2	-1.6	0.5	1.5
Medication: Simvastatin	1.7	2.4	4.4	-2.0	-0.8	-2.0	1.2	-1.8	-1.6	-2.1	-1.9	-0.3	0.1
Migraine (self-reported)	1.7	2.1	5.0	1.2	-2.2	1.9	0.3	1.7	0.8	1.7	1.4	0.0	-1.7
Family relationship satisfaction	1.7	2.1	4.5	1.3	0.7	1.6	-1.2	1.5	1.0	1.7	1.6	2.1	-1.2
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.0	4.3	1.8	-1.6	2.1	1.2	1.6	1.1	1.2	1.5	0.8	-0.3
Number of self-reported non-cancer illnesses	1.7	3.0	8.3	-1.7	-1.0	-2.9	1.4	-1.5	-1.8	-1.4	-1.3	-2.4	1.1
Financial situation satisfaction	1.7	2.1	6.7	1.7	-1.3	0.9	2.6	1.3	1.0	0.1	1.3	-0.9	-1.9
Pain type(s) experienced in last month: Hip pain	1.7	2.1	11.4	0.6	-3.4	-0.8	0.8	0.9	1.9	0.6	0.4	-0.7	-1.8
Bipolar Disorder or Schizophrenia	1.6	3.9	8.2	2.5	-0.1	2.3	-1.2	2.9	1.9	2.6	2.5	0.7	-0.9
Number of treatments/medications taken	1.5	2.6	8.2	-1.7	-0.3	-2.9	1.9	-1.6	-1.4	-1.6	-1.3	-1.0	1.3
Relative age voice broke	1.5	2.2	5.2	1.7	0.9	1.6	-0.7	1.6	0.9	1.7	2.3	1.6	-1.2
Hearing difficulty/problems with background noise	1.5	2.4	6.5	-2.6	-0.8	-0.9	0.9	-2.3	-1.8	-0.9	-1.9	-1.0	0.8
Blood clot in the leg (DVT)	1.5	1.9	4.6	-1.4	0.2	-1.3	-1.4	-1.2	-2.1	-1.7	-1.5	1.3	0.9
Mouth/teeth dental problems: Loose teeth	1.5	1.8	5.0	1.5	-0.3	2.2	1.7	1.4	1.2	1.4	1.5	-0.7	-0.4
Medication: Gliclazide	1.5	1.7	4.1	-1.9	-1.0	-1.5	0.4	-1.7	-0.8	-1.5	-2.0	0.2	0.2
Illnesses of father: High blood pressure	1.5	1.9	5.3	-1.7	-1.2	-1.0	-0.7	-1.2	-0.8	-1.7	-2.3	0.6	-1.5
Alzheimer’s Disease (in mother)	1.4	1.7	5.2	-0.4	-1.7	-0.6	2.2	-0.6	1.0	-0.4	-0.3	-2.3	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	5.6	-1.8	0.0	-1.2	0.5	-2.1	-2.4	-1.5	-1.6	0.2	1.4
Osteoporosis (self-reported)	1.4	1.7	4.6	-1.3	0.5	-1.4	1.1	-1.3	-2.1	-0.9	-1.2	-1.1	1.4
Mother’s age at death	1.4	1.7	3.7	1.6	-1.0	1.3	0.4	1.6	1.6	1.9	1.7	0.1	0.1
Number of operations (self-reported)	1.4	2.0	5.0	-2.2	0.7	-2.0	-0.3	-1.7	-1.7	-1.1	-1.7	-0.1	0.9
LDL Cholesterol	1.3	2.1	6.0	1.4	-0.0	1.6	-1.0	1.9	0.1	2.5	1.6	-0.4	-1.8
Ulcerative Colitis	1.3	1.8	3.9	1.7	-1.8	1.0	2.0	1.4	1.7	-0.2	1.4	-0.2	-0.8
Relative age of first facial hair	1.3	2.6	6.8	-1.8	1.9	-0.7	-0.8	-2.5	-2.6	-1.5	-1.3	1.1	-0.6
Systolic blood pressure, automated reading	1.3	3.9	10.2	-2.5	-0.7	-3.2	0.2	-1.8	-1.6	-2.4	-2.3	-2.1	1.0
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	4.2	-1.3	-0.3	-1.9	0.4	-0.3	-1.4	-1.2	-1.4	-2.0	-0.2
Hair/balding pattern: Pattern 2	1.3	1.6	7.8	0.6	-1.9	1.0	-0.3	0.7	-0.2	1.2	1.0	0.4	-2.8
Smoking status: Current	1.3	2.0	5.5	-1.3	-0.9	-1.2	0.8	-1.2	-0.9	-1.7	-1.4	-2.3	1.8
Trunk fat percentage	1.2	4.7	7.8	2.2	-2.7	2.1	2.4	2.0	2.8	1.9	2.4	1.0	-1.5
Current tobacco smoking	1.2	2.0	5.2	-1.2	-0.7	-1.3	0.6	-1.1	-0.9	-1.6	-1.3	-2.3	2.1
Hip circumference	1.2	5.0	9.5	1.7	-3.1	2.9	1.3	2.1	2.7	2.3	1.8	2.2	-1.7
Lung cancer (father)	1.2	1.4	4.0	-0.9	0.4	-1.8	1.8	-0.6	-0.8	-0.8	-0.5	-2.0	1.2
Loud music exposure frequency	1.2	1.3	8.0	-0.1	-0.3	0.4	2.8	-0.3	-0.1	-0.0	0.4	-1.9	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	2.7	-1.7	1.5	-1.2	0.4	-1.4	-1.6	-0.9	-1.6	-0.3	1.2
Eye problems/disorders: None of the above	1.2	1.4	3.7	1.0	-0.7	1.6	1.9	1.2	0.5	1.2	1.0	-1.2	-0.2
Medication: Omeprazole	1.2	1.4	6.3	-0.5	-1.7	-1.0	2.5	-0.2	0.6	-0.3	-0.5	-1.1	1.2
Asthma (self-reported)	1.2	2.3	5.1	1.8	0.8	1.8	-0.5	2.2	2.1	1.8	1.8	0.0	0.5
Wears glasses or contact lenses	1.2	1.4	4.8	-1.0	0.6	-1.2	0.6	-1.6	-0.5	-0.7	-0.6	-1.6	2.2
Tinnitus: Yes, now most or all of the time	1.2	1.3	3.7	-1.2	1.1	-1.1	-1.1	-0.5	-0.8	-0.8	-1.8	1.9	0.1
Commuting to job workplace: Public transport	1.2	1.4	3.6	1.3	-0.6	1.1	1.8	1.0	-0.7	0.4	1.3	0.8	-1.9
Ever depressed for a whole week	1.2	1.5	3.8	1.0	-1.4	1.8	1.9	0.7	0.5	1.5	1.0	-0.6	-1.2
High blood pressure (mother)	1.1	1.5	3.1	-1.3	-1.3	-1.0	1.4	-1.2	-1.8	-1.2	-1.0	-1.4	-0.1
Forced vital capacity (FVC), Best measure	1.1	3.9	7.9	2.4	-1.8	2.8	0.5	2.3	1.4	2.3	1.9	-0.2	-2.4
Osteoarthritis (self-reported)	1.1	1.4	3.7	-1.3	1.0	-1.5	0.8	-1.4	-0.4	-1.0	-0.9	-1.9	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	5.3	1.8	-0.2	2.3	-0.0	1.7	0.9	2.2	1.8	-0.8	-1.3
Heart attack/myocardial infarction (self-reported)	1.1	1.4	3.4	-1.5	0.5	-1.8	-0.3	-1.3	-0.4	-1.8	-1.2	0.4	0.9
Primary Biliary Cirrhosis	1.0	1.4	2.8	1.5	-0.4	0.9	0.7	1.7	1.4	1.3	1.1	-0.2	-1.6
Falls in the last year	1.0	1.4	3.6	-1.3	-1.6	-1.4	0.6	-1.9	0.1	-1.4	-0.9	-0.2	0.6
Pulse rate	1.0	1.6	4.7	-0.9	2.1	-1.5	1.5	-0.9	-2.2	-1.0	-0.8	-0.2	-0.1
Asthma	1.0	2.0	4.2	1.6	0.8	1.6	-0.6	2.0	1.8	1.8	1.6	-0.0	0.6
Chronic bronchitis/emphysema (mother)	1.0	1.1	2.9	-1.0	1.0	-0.6	-1.2	-1.2	-1.0	-0.7	-1.1	1.7	-0.6
Body fat percentage	1.0	4.0	6.7	1.9	-2.6	1.9	2.5	1.8	2.6	1.6	2.1	1.1	-1.3
Shortness of breath walking on level ground	1.0	1.2	3.1	-1.7	0.2	-1.5	-0.0	-1.2	-0.2	-1.2	-1.8	0.1	0.8
Loneliness, isolation	1.0	1.4	2.6	-1.6	0.4	-1.4	0.4	-1.4	-1.5	-0.9	-1.5	-0.6	1.3
Ever had bowel cancer screening	1.0	1.1	2.9	0.6	-0.9	1.0	1.5	0.7	0.9	1.7	0.7	-0.7	-1.3
Diabetes diagnosed by doctor	1.0	1.7	3.5	-1.7	0.5	-1.6	1.0	-1.1	-1.7	-1.6	-1.9	0.6	-0.5
Diastolic blood pressure, automated reading	1.0	3.1	5.4	-2.3	-0.9	-2.3	-1.1	-1.6	-1.2	-2.2	-2.2	-1.5	1.7
Crohns Disease (2017)	0.9	1.9	5.2	-1.8	0.0	-1.4	1.1	-1.1	-1.5	-2.3	-1.9	0.3	0.5
Respiratory disease	0.9	2.0	4.9	1.6	0.4	1.0	0.0	1.8	2.0	1.7	2.2	-0.7	0.8
Average weekly spirits intake	0.9	1.1	4.3	0.8	-2.1	0.3	0.8	0.8	2.0	0.6	0.2	-0.1	-0.3
Sensitivity / hurt feelings	0.9	1.6	8.0	-0.9	-0.6	-0.2	2.8	-1.2	-1.1	-1.0	-0.7	-1.0	1.1
Hearing difficulty/problems: Yes	0.9	1.4	3.9	-2.0	-0.3	-0.1	-0.3	-1.9	-1.3	-0.7	-1.7	1.2	0.5
Ever had hysterectomy (womb removed)	0.9	1.0	3.3	-0.8	0.8	-1.4	0.8	-0.8	0.4	-0.7	-0.5	1.1	1.8
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	4.2	-0.2	1.3	0.1	-1.6	0.2	-0.4	0.2	-0.1	-2.1	1.2
Multivitamins +/- minerals	0.9	1.1	2.4	1.1	-1.5	1.0	1.3	0.8	1.5	0.5	0.5	1.2	0.3
Sitting height	0.9	6.6	15.7	2.6	-2.0	3.5	-0.4	2.8	2.9	4.0	3.0	0.0	-1.2
Trunk fat mass	0.9	4.1	7.1	1.8	-2.7	2.1	2.2	1.9	2.7	1.9	2.0	1.2	-1.1
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.4	1.2	-0.3	1.2	1.4	0.8	0.8	0.6	1.2	-1.0	-1.5
Forced expiratory volume in 1-second (FEV1)	0.9	3.1	7.8	2.0	-0.9	2.7	-0.5	2.0	0.8	1.8	1.6	-0.2	-2.8
Leg fat percentage (right)	0.9	3.1	6.3	1.7	-2.0	1.8	2.5	1.7	2.4	1.4	1.8	0.6	-0.7
Pulse wave peak to peak time	0.9	1.1	2.1	1.2	0.7	0.8	-1.2	0.9	0.1	1.0	1.1	1.2	-1.4
Qualifications: College or University degree	0.9	3.0	7.1	1.8	-1.3	2.4	-0.8	1.7	1.1	2.0	1.8	-0.2	-2.7
Medication: Allopurinol	0.9	1.2	3.8	-0.7	0.6	-1.2	0.6	-0.7	-0.7	-2.0	-1.7	0.9	0.3
Overall health rating	0.9	1.9	4.7	-2.0	-1.0	-2.2	-0.2	-1.8	-0.5	-1.6	-1.6	0.5	0.2
Supplements: Vitamin C	0.9	1.1	3.9	0.7	-1.1	1.3	0.5	0.8	1.1	2.0	1.0	0.6	-0.1
Average weekly red wine intake	0.9	1.3	2.3	1.3	-0.8	1.2	1.0	1.3	0.6	1.5	1.0	-1.4	-0.6
Guilty feelings	0.9	1.4	4.7	-1.1	-0.9	-0.8	1.8	-1.0	-1.1	-0.3	-0.9	-2.2	0.4
Eye problems/disorders: Glaucoma	0.9	1.1	3.1	-1.1	0.4	-1.8	-0.4	-1.2	-0.9	-1.1	-0.9	-0.3	1.2
Alcohol drinker status: Never	0.9	1.1	3.9	-0.6	1.2	-1.1	0.9	-1.0	-1.2	0.0	0.6	-0.8	2.0
Schizophrenia (2018)	0.8	1.6	4.6	1.8	0.2	1.2	-0.8	1.7	0.8	1.4	2.2	-0.1	0.0
HDL Cholesterol	0.8	1.3	3.9	1.3	-0.9	2.0	0.2	0.7	1.8	0.5	1.0	0.6	-0.8
Schizophrenia (2014)	0.8	1.8	4.8	1.9	0.2	1.3	-1.0	1.9	0.9	1.5	2.2	0.3	0.4
Triglycerides	0.8	1.2	2.7	-1.4	0.3	-1.2	-1.3	-1.6	-1.3	-1.1	-1.1	0.6	0.5
Waist Hip Ratio (WHR)	0.8	3.8	6.5	-2.2	2.5	-2.4	-0.1	-1.9	-1.9	-1.7	-2.2	-1.8	1.7
Ever used hormone-replacement therapy (HRT)	0.8	1.1	4.1	-0.3	0.6	-0.5	1.1	-0.4	0.4	0.6	-0.0	-2.0	2.0
Supplements: Zinc	0.8	0.8	3.9	-0.1	-0.5	1.0	0.7	0.5	1.4	0.4	-0.2	2.0	0.5
Medication: Co-codamol	0.8	0.9	1.9	-1.2	0.6	-1.2	-0.3	-1.4	-0.7	-0.7	-1.3	1.2	0.3
Diabetes (mother)	0.8	1.0	3.6	0.6	-1.9	1.5	0.9	0.4	1.3	0.6	0.7	0.3	0.3
Serious illness, injury or assault to yourself	0.8	1.0	2.5	1.0	-0.6	1.0	1.5	1.2	0.9	1.6	0.7	0.5	-0.1
Stomach or abdominal pain in last month	0.8	1.0	2.5	0.9	-1.2	1.1	-0.2	1.3	1.6	1.2	0.8	0.6	-0.2
Had menopause	0.8	1.0	2.9	0.9	-0.0	0.2	1.1	0.8	1.7	0.8	0.8	-1.6	0.7
Qualifications: None of the above	0.8	1.7	4.8	-1.6	1.2	-2.2	-0.2	-1.5	-0.7	-1.4	-1.5	-0.3	1.2
Arm fat percentage (right)	0.8	3.1	5.8	1.6	-2.2	1.8	2.4	1.6	2.2	1.4	1.8	1.4	-0.9
Breastfed as a baby	0.8	1.0	3.3	-0.6	-0.3	-0.6	1.8	-0.9	-1.1	-0.3	-0.6	-1.4	1.1
Commuting to job workplace: Car/motor vehicle	0.8	0.9	4.9	-1.0	-0.6	-1.3	0.1	-0.6	0.0	-0.4	-0.8	-0.6	2.2
Hearing aid user	0.8	0.9	5.2	0.9	-0.4	1.0	-0.7	0.9	0.7	0.2	0.5	0.1	-2.3
Leg fat percentage (left)	0.8	2.8	6.3	1.4	-2.1	1.7	2.5	1.5	2.3	1.3	1.5	0.7	-0.4
Alzheimer’s Disease (in father)	0.7	0.8	2.4	0.9	0.2	0.6	-0.3	1.2	0.8	0.8	1.1	-0.6	-1.5
Alzheimer’s Disease (including proxy)	0.7	0.9	4.0	0.1	-0.9	-0.2	1.6	0.2	1.3	0.1	0.1	-2.0	0.6
Severe depression (siblings)	0.7	0.8	2.6	-0.8	0.8	-1.3	-0.4	-0.9	-0.6	-1.6	-1.0	0.3	-0.3
Maternal smoking around birth	0.7	1.0	2.5	-1.1	1.4	-0.4	-1.6	-1.0	-0.6	-0.6	-1.1	0.3	0.8
Impedance of arm (right)	0.7	3.3	8.8	3.0	-0.6	1.8	0.0	2.0	2.0	1.7	2.7	0.2	-1.4
Father’s age at death	0.7	0.9	3.2	1.0	-0.5	0.8	-0.5	0.4	-0.0	1.8	1.0	-0.4	-1.6
Depression (self-reported)	0.7	0.8	2.1	0.9	-1.5	1.3	1.1	0.5	-0.1	0.9	0.8	-0.7	0.2
Tense / ‘highly strung’	0.7	1.2	2.7	0.9	-1.5	1.6	0.9	1.2	1.2	1.1	1.0	0.8	0.4
Pulse wave reflection index	0.7	0.8	2.5	-1.1	-1.1	0.2	0.1	-1.4	0.5	-0.7	-0.9	0.1	1.6
Medication: Paracetamol	0.7	1.2	3.0	1.1	0.4	1.2	0.5	1.3	1.7	1.1	1.4	0.0	0.7
Whole body fat mass	0.7	3.0	5.6	1.4	-2.4	1.8	2.1	1.5	2.1	1.5	1.7	1.2	-0.8
Suffer from ‘nerves’	0.7	1.1	3.2	1.1	-0.6	1.5	-0.7	0.7	1.8	1.2	1.2	-0.5	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.6	-1.1	0.5	-1.6	0.4	-0.7	-0.6	-1.2	-1.0	0.6	-0.4
Arm fat percentage (left)	0.7	2.9	4.8	1.5	-1.9	1.9	2.2	1.5	2.2	1.3	1.7	1.7	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.9	-1.2	-0.9	-0.2	1.0	-0.0	-0.8	-0.3	-1.7	-0.4	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	4.3	-0.6	-0.6	-1.0	2.1	-0.3	0.3	-0.2	-0.6	-1.0	1.1
Neuroticism (Nagel 2018)	0.6	1.4	6.9	0.5	-2.6	0.7	1.7	0.4	1.0	0.5	0.8	-1.0	0.5
Age at First Birth	0.6	0.8	3.6	-0.3	-0.0	-0.6	1.9	-0.9	-0.1	0.2	-0.1	0.4	1.7
Lung FEV1/FVC ratio	0.6	3.2	11.5	2.0	-1.2	1.6	-0.8	1.9	0.8	1.4	2.3	0.3	-3.4
Average weekly fortified wine intake	0.6	0.7	2.4	0.4	-0.9	1.2	-0.8	0.6	0.7	0.4	0.3	-1.6	-0.3
Hair/balding pattern: Pattern 3	0.6	0.9	4.2	-1.0	-0.5	-1.1	0.0	-0.8	-0.8	-2.1	-1.1	-0.1	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	2.0	0.7	-1.2	1.4	0.7	-0.1	0.6	1.0	0.8	0.4	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	3.9	0.3	-0.6	-0.9	2.0	-0.1	0.1	-0.9	0.4	-1.2	0.1
Prospective memory result	0.6	0.8	2.3	-1.4	-0.5	-1.1	0.1	-0.8	0.4	-0.8	-1.5	0.3	0.2
Pulse wave Arterial Stiffness index	0.6	0.7	2.1	-0.9	-0.7	-0.6	0.8	-0.7	0.1	-0.6	-0.9	-0.9	1.4
Impedance of arm (left)	0.6	2.8	7.1	2.7	-0.4	1.8	0.1	1.6	1.9	1.4	2.3	0.9	-1.8
Length of working week for main job	0.6	0.7	2.7	0.6	0.2	0.8	-1.6	0.4	0.2	1.5	0.4	0.7	-0.5
Exposure to tobacco smoke at home	0.6	0.7	2.5	0.1	-1.2	0.7	-0.6	-0.5	0.2	0.0	-0.2	1.6	-1.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.0	1.1	0.7	0.9	-0.3	1.1	0.4	0.9	1.4	1.0	0.1
Headache pain in last month	0.6	1.0	5.0	-0.1	0.8	-0.7	0.6	-0.0	-0.7	0.3	0.7	-2.2	1.5
Glaucoma (self-reported)	0.6	0.7	2.7	-0.5	0.5	-1.6	0.4	-1.0	-0.2	-0.7	-0.2	0.2	1.6
Medication: Ibuprofen	0.6	0.7	1.9	-0.2	0.6	-1.4	1.3	-0.5	-0.7	-0.8	0.1	-0.9	0.7
Leg fat mass (right)	0.6	2.5	4.9	1.2	-2.0	1.6	2.2	1.4	2.0	1.5	1.5	1.1	-0.4
Number of full sisters	0.6	0.7	2.2	1.1	0.4	0.8	0.6	0.9	0.9	0.6	1.5	0.7	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.9	-1.4	0.6	-0.6	-0.5	-0.5	-1.0	-0.5	-1.4	0.8	0.7
Arm fat mass (left)	0.6	2.6	4.8	1.2	-2.2	1.8	2.0	1.4	1.9	1.4	1.4	1.5	-0.7
Miserableness	0.6	1.1	2.5	1.3	-0.6	1.3	0.3	1.6	0.8	1.3	1.2	0.2	-1.0
Ever taken oral contraceptive pill	0.6	0.7	2.5	0.2	-1.2	0.5	-0.0	0.4	0.6	0.8	-0.1	-1.3	-1.6
Average weekly beer plus cider intake	0.6	0.9	2.2	-1.5	0.6	-1.2	0.2	-0.6	-0.4	-1.0	-1.1	0.3	1.3
Commuting to job workplace: Cycle	0.6	0.7	2.8	-0.5	-0.4	0.6	-1.7	-0.7	-0.1	-0.3	-0.4	1.1	-1.2
Leg fat mass (left)	0.6	2.3	4.8	1.0	-2.1	1.5	2.2	1.2	2.0	1.4	1.2	1.2	-0.2
Worry (Nagel 2018)	0.5	1.0	3.8	0.8	-1.9	1.1	0.6	0.4	1.4	0.7	0.8	-0.5	0.8
Chronotype (morning person)	0.5	1.2	2.8	-1.2	0.5	-1.3	0.5	-1.3	-1.6	-1.7	-1.0	0.7	0.4
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	2.2	-0.8	-0.4	-0.2	-0.5	-0.6	-0.7	-0.8	-1.5	0.3	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	5.1	0.1	-0.5	0.6	2.3	0.3	0.3	0.8	0.7	-0.9	0.7
Forced vital capacity (FVC)	0.5	1.9	5.5	1.6	-1.0	2.3	-0.2	1.5	0.7	1.8	1.2	-0.6	-1.6
Arm fat mass (right)	0.5	2.2	4.2	1.1	-2.1	1.4	2.0	1.3	1.7	1.4	1.3	1.3	-0.6
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	1.0	-0.5	0.8	0.6	0.4	1.3	0.0	0.9	0.4	-1.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	1.8	1.1	-1.2	1.1	0.3	0.6	1.0	0.9	1.3	0.3	-0.8
Gout (self-reported)	0.5	0.7	2.4	-0.7	0.2	-0.6	0.8	-0.6	-0.9	-0.9	-1.5	1.0	-0.4
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.4	-1.3	-0.4	-0.8	-0.1	-1.2	-1.5	-0.9	-1.1	-0.8	0.6
Medication: Ventolin 100micrograms inhaler	0.5	0.7	1.8	-0.7	1.3	-0.6	-1.3	-0.4	-0.9	0.3	-0.5	0.7	0.9
Exposure to tobacco smoke outside home	0.5	0.7	2.9	0.5	-0.7	1.0	-0.2	0.4	0.4	0.9	0.4	1.7	-0.9
Worry too long after embarrassment	0.5	0.9	2.8	0.4	-1.6	1.7	0.5	0.3	1.2	0.7	0.6	0.7	-0.5
Illnesses of siblings: Diabetes	0.5	0.6	1.4	-1.0	0.1	-0.5	-0.8	-1.1	0.2	-1.2	-1.1	0.7	0.2
Illnesses of father: None of the above (group 1)	0.5	0.6	1.3	1.1	-0.8	0.3	0.6	0.5	1.0	0.5	0.9	0.3	1.0
Average weekly champagne plus white wine intake	0.5	0.8	3.0	-0.7	-0.9	-0.7	0.1	-0.8	-1.7	-0.1	-0.4	-1.1	0.7
Heart disease (siblings)	0.5	0.6	1.5	-0.8	0.4	-1.2	-0.3	-0.7	-0.3	-0.3	-0.6	-1.1	1.1
Impedance of whole body	0.5	2.3	6.5	2.6	-0.3	1.5	-0.1	1.6	2.0	1.1	2.0	0.3	-1.6
Ulcerative Colitis (UC)	0.4	0.7	1.8	1.2	0.1	0.7	1.1	1.2	1.3	-0.2	0.9	0.1	-0.4
Ovarian Cancer	0.4	0.5	2.8	-0.3	-0.4	0.0	1.7	-0.6	0.2	-0.8	-0.6	-0.3	0.3
Neuroticism (2016)	0.4	0.5	1.7	-0.8	-1.3	0.2	-0.4	-1.1	0.2	-0.5	-1.1	0.0	0.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.4	-0.7	0.5	-0.3	0.7	-0.2	-0.9	-1.1	-0.8	1.2	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.2	0.6	0.1	1.0	0.7	0.7	0.7	1.1	0.9	0.8	0.4
Taking other prescription medications	0.4	0.6	2.4	-0.4	-0.5	-0.9	1.6	-0.3	-0.4	0.2	0.0	-0.7	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	1.9	-1.3	1.1	0.1	-0.8	-1.2	-1.1	-0.3	-1.3	-0.1	1.4
Supplements: Glucosamine	0.4	0.5	1.0	-1.0	1.0	-0.1	-0.7	-0.8	-0.7	0.5	-0.8	0.5	0.7
Waist circumference	0.4	1.3	3.7	0.5	-1.7	0.9	1.9	1.0	1.5	1.2	0.6	0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	3.0	-1.1	1.1	0.3	-0.4	-1.0	-0.6	-0.2	-0.9	0.6	1.7
Neuroticism score	0.4	0.9	2.0	0.9	-1.4	1.4	0.6	0.6	1.2	0.7	1.1	0.4	-0.0
Weight	0.4	2.0	5.2	0.8	-2.3	1.5	1.4	1.2	1.8	1.7	1.1	1.1	-0.3
Hair/balding pattern: Pattern 4	0.4	1.0	4.4	-0.2	1.7	0.2	2.1	-0.7	-0.3	-0.9	-0.5	0.2	0.9
Peak expiratory flow (PEF)	0.4	0.9	4.3	-0.3	0.6	-0.1	-1.7	0.2	-1.2	-0.1	-0.5	-0.3	-2.1
Health satisfaction	0.4	0.5	1.2	-0.8	0.2	-0.9	-0.7	-0.3	-0.2	-0.4	-0.8	1.1	-0.8
Emphysema/chronic bronchitis	0.4	0.4	1.9	-0.1	-1.4	-0.6	1.1	-0.1	-0.1	0.1	0.3	-0.7	-0.6
Medication for pain relief, constipation, heartburn	0.4	0.8	1.9	0.6	-1.0	1.1	-1.2	0.0	-0.1	1.0	0.4	0.7	-1.4
Leg pain on walking	0.4	0.5	2.7	0.2	0.7	0.0	1.6	0.2	0.4	0.6	0.5	-1.2	0.1
Knee pain experienced in last month	0.4	0.7	3.7	-0.8	-0.7	-0.3	1.9	-0.9	0.3	-0.9	-0.4	-0.1	0.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.0	0.2	1.4	-0.7	-1.1	0.5	-0.3	-0.7	0.0	-0.8	0.2
Long-standing illness, disability or infirmity	0.4	0.7	3.4	-0.7	-0.4	-1.1	1.8	-0.7	-0.5	-0.9	0.1	-0.2	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.8	-0.7	-0.7	-0.4	0.4	-0.2	-1.0	-0.6	-0.7	-1.7	-0.8
Back pain experienced in last month	0.4	0.6	1.5	0.8	0.6	0.4	0.1	1.2	0.6	1.1	0.6	0.8	-1.0
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.7	0.4	0.8	-0.1	-0.6	0.5	1.0	0.6	0.5	1.3	0.2
High cholesterol (Self-reported)	0.4	0.7	2.4	-0.4	-1.0	-0.6	1.4	-0.3	-0.8	-0.1	-0.4	-0.5	-1.6
Medication: Paracetamol	0.4	0.5	1.7	0.2	1.3	0.3	0.4	0.2	0.6	0.6	0.6	-0.7	1.3
Medication: Atorvastatin	0.4	0.5	1.5	0.3	-1.2	0.2	1.0	0.4	1.2	0.8	0.2	0.4	-0.1
Cholesterol lowering medication	0.4	0.5	4.5	0.2	-0.2	-0.0	0.6	0.5	0.2	0.1	0.4	-0.2	-2.1
Alcohol drinker status: Previous	0.4	0.5	2.1	0.2	0.3	0.6	-1.0	0.4	0.3	1.1	0.3	1.4	-0.3
Pack years of smoking	0.4	0.5	2.4	0.7	0.3	0.1	0.5	0.6	1.6	0.3	0.3	-0.1	1.3
Depression (Nagel 2018)	0.3	0.5	1.5	0.6	0.2	0.2	1.2	0.7	0.6	0.7	1.1	-0.5	0.3
Verbal and Numeric Reasoning (VNR)	0.3	0.6	2.1	0.1	1.5	0.2	0.4	0.2	-0.5	-1.1	0.0	1.0	-1.3
Prostate Cancer	0.3	0.4	1.4	0.4	1.0	0.1	-1.2	0.3	-0.8	0.3	0.4	-0.3	0.1
Fasting Glucose	0.3	0.4	1.9	0.6	1.4	0.2	-0.7	0.9	-0.3	0.0	0.3	0.0	-0.2
Rheumatoid Arthritis	0.3	0.4	1.5	-0.7	-0.2	-1.2	-0.5	-0.5	0.4	-0.3	-0.6	0.4	0.6
Blood White Count	0.3	1.9	3.3	-1.4	1.4	-1.4	-0.2	-1.5	-1.5	-1.5	-1.8	0.7	1.3
Neuroticism	0.3	0.7	2.8	0.6	-1.7	0.8	1.3	0.3	0.8	0.4	0.9	-0.1	0.4
Tanning	0.3	3.9	9.8	-2.2	-0.5	-3.1	0.5	-2.6	-1.9	-2.9	-2.1	-0.3	0.7
Hand grip strength (left)	0.3	0.9	2.5	-0.1	-0.5	0.7	-1.6	0.1	0.2	1.4	0.0	-1.1	1.6
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.3	0.4	-0.1	0.7	1.1	0.5	0.2	0.7	0.8	-0.1	-1.1
Diabetes (father)	0.3	0.3	1.8	-0.5	-0.5	0.2	-0.2	-0.2	-0.6	-0.2	-0.7	0.4	-1.3
Pack years adult smoking proportion	0.3	0.4	2.1	0.7	0.5	0.1	0.2	0.5	1.4	-0.0	0.1	0.3	1.0
Leg fat-free mass (left)	0.3	1.4	4.1	0.5	-2.0	1.5	0.6	0.9	1.1	1.6	0.9	1.4	-0.3
Townsend deprivation index at recruitment	0.3	0.4	2.1	-0.3	1.5	0.1	0.2	-0.4	-0.9	-0.3	-0.3	-0.4	0.1
Fed-up feelings	0.3	0.6	2.3	-0.3	-1.3	0.5	1.5	-0.3	-0.1	-0.4	-0.3	0.9	-0.7
Age when periods started (menarche)	0.3	0.7	2.0	-0.4	-1.4	-0.4	-1.2	-0.6	0.9	-0.8	-0.8	0.4	-0.7
Body mass index (BMI)	0.3	1.2	3.9	0.5	-1.7	1.0	2.0	0.8	1.2	0.8	0.8	0.9	-0.2
Leg predicted mass (left)	0.3	1.5	4.0	0.5	-2.0	1.6	0.6	0.9	1.1	1.6	1.0	1.4	-0.4
Number of incorrect matches in round	0.3	0.6	1.6	-0.9	-0.1	-0.6	-0.3	-1.2	-0.1	-0.6	-1.3	-0.2	0.9
Alcohol usually taken with meals	0.3	0.5	2.3	0.8	-1.5	0.4	0.0	0.2	0.9	1.0	0.4	-0.6	0.4
Nervous feelings	0.3	0.6	1.4	0.7	-0.3	1.2	-0.2	0.5	0.7	0.8	1.2	0.5	0.7
Financial difficulties in last 2 years	0.3	0.4	1.1	-0.1	-0.2	-0.5	-0.9	-0.1	0.4	-0.7	-0.3	1.0	-1.1
Fluid intelligence score	0.3	0.7	1.9	0.0	1.1	-0.6	0.2	0.0	-1.4	-1.0	-0.1	-0.7	-1.3
Number of live births	0.3	0.4	1.3	-0.4	0.6	-0.5	-1.0	-0.2	-1.1	0.1	-0.1	0.5	0.7
Birth weight	0.3	0.7	2.8	-0.2	1.5	0.1	-0.5	-0.2	-0.3	1.0	-0.1	0.3	1.7
Pulse rate, automated reading	0.3	1.1	5.8	0.1	1.9	-0.7	0.6	0.2	-0.0	-0.5	-0.1	-2.4	0.3
Chest pain or discomfort	0.3	0.4	1.6	0.6	1.3	-0.0	-0.6	0.3	0.2	0.4	1.0	0.7	0.1
Age at last live birth	0.3	0.5	3.7	-0.6	0.1	-0.1	-1.9	-0.5	-0.3	-0.1	-0.6	0.2	0.0
Leg fat-free mass (right)	0.3	1.5	4.4	0.5	-2.1	1.5	0.3	0.9	1.1	1.7	0.9	1.5	-0.2
Eye problems/disorders: Cataract	0.3	0.3	1.3	0.2	0.8	-0.9	-1.2	0.2	0.2	-0.3	0.2	-0.1	-0.4
Leg predicted mass (right)	0.3	1.4	4.4	0.4	-2.1	1.5	0.4	0.8	1.1	1.6	0.9	1.5	-0.2
Depressed Affect (Nagel 2018)	0.2	0.5	2.6	-0.1	-1.6	-0.2	1.1	-0.0	0.4	-0.0	-0.0	-0.8	0.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.7	0.1	1.5	0.4	-0.7	0.5	-0.2	-0.7	-0.1	0.7	-1.6
Schizophrenia vs Biploar Disorder	0.2	0.3	1.1	0.8	0.1	0.3	-0.0	0.5	1.0	-0.1	1.0	-0.1	0.4
Irritable Bowel Disease (IBD)	0.2	0.4	1.9	-0.2	0.1	-0.5	1.0	0.3	-0.1	-1.4	-0.5	0.3	-0.1
Lupus	0.2	0.3	1.6	-0.7	-0.4	-0.2	-0.0	-0.8	-0.2	-0.4	-0.2	0.1	1.3
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.6	0.1	-0.2	0.5	0.5	0.3	0.7	-0.0	-0.2	0.5	-0.8
Heel T-Score	0.2	1.2	2.0	-1.4	1.0	-1.3	0.3	-1.0	-0.4	-1.4	-1.4	0.8	1.2
Hypothyroidism (self reported)	0.2	0.5	0.9	-0.9	-0.9	-0.4	-0.3	-1.0	-0.9	-0.5	-0.8	-0.1	0.4
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.4	0.5	-0.5	-0.1	0.5	0.4	0.6	0.7	0.6	0.6	-0.2
Impedance of leg (right)	0.2	0.8	2.7	1.6	0.1	0.6	0.1	1.0	0.9	0.4	1.0	-0.1	-1.3
Hand grip strength (right)	0.2	0.6	2.7	-0.3	-0.1	0.5	-1.7	0.1	0.0	0.6	-0.5	-1.2	1.0
Impedance of leg (left)	0.2	0.9	2.9	1.7	-0.3	0.7	0.1	1.1	1.4	0.5	1.0	0.1	-1.0
Mouth/teeth dental problems	0.2	0.3	1.2	0.1	-1.1	0.3	-0.7	-0.4	-0.3	0.6	0.3	-0.1	-0.9
Pain all over the body in last month	0.2	0.2	0.7	-0.4	0.4	-0.6	0.5	-0.3	-0.9	0.0	0.4	-0.4	0.3
Worrier / anxious feelings	0.2	0.4	1.1	0.4	-0.6	1.0	0.5	0.2	1.1	0.7	0.5	-0.4	0.3
Noisy workplace	0.2	0.3	0.8	0.3	-0.3	0.4	0.6	0.1	0.8	0.6	0.5	-0.9	-0.2
Wheeze or whistling in the chest in last year	0.2	0.3	1.7	-0.0	0.2	-0.4	-0.5	0.3	1.0	0.0	0.0	0.4	1.3
Age at first live birth	0.2	0.4	1.7	0.1	-1.3	0.6	0.4	-0.1	0.2	-0.0	0.1	-0.0	-1.2
Medication: Seretide 50 evohaler	0.2	0.3	0.9	0.7	-0.2	0.6	-0.2	-0.0	1.0	0.6	0.6	0.2	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.9	-0.1	1.0	0.0	0.1	0.5	0.1	-0.8	-0.7	-0.6	0.6
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.4	-0.2	0.3	-0.3	0.3	0.2	-0.5	-0.4	0.2	-1.2	-0.3
Illnesses of father: Heart disease	0.2	0.3	0.7	-0.8	-0.9	0.2	-0.1	-0.6	-0.8	0.1	-0.4	-0.2	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	2.0	0.2	0.3	0.7	-0.2	0.5	-0.4	0.3	-0.2	1.4	-1.0
Mood swings	0.2	0.4	1.2	-0.7	-0.7	-0.3	0.9	-0.9	-0.1	-0.3	-0.5	0.1	1.1
Mineral and other dietary supplements	0.2	0.3	1.2	0.4	-0.6	0.1	0.7	0.4	-0.5	-0.4	0.4	-1.1	0.1
Basal metabolic rate	0.2	1.1	4.2	0.1	-2.1	1.2	0.7	0.7	1.0	1.4	0.5	1.1	-0.0
Arm fat-free mass (left)	0.2	0.9	5.1	-0.0	-2.3	0.7	0.5	0.6	0.8	1.3	0.3	0.3	0.3
Fractured/broken bones in last 5 years	0.2	0.2	1.0	-0.2	0.1	-0.3	-1.0	-0.1	-0.2	-0.2	-0.7	0.4	-0.2
Age started oral contraceptive pill	0.2	0.3	0.9	-0.2	-0.5	-0.2	-0.6	-0.7	0.7	0.2	-0.1	-0.2	0.9
Unable to work because of sickness or disability	0.2	0.3	1.8	-0.3	-0.5	0.0	1.3	-0.7	0.2	-0.4	-0.1	0.2	0.0
BMI	0.1	0.5	2.7	-0.8	-0.8	-0.3	1.6	-0.4	-0.0	-0.1	-0.3	0.3	0.0
Height	0.1	1.6	5.8	0.7	-1.1	1.1	-1.7	0.7	1.7	2.4	0.6	0.5	0.3
Lung FVC	0.1	0.5	1.4	0.4	0.2	0.4	1.1	0.3	-0.7	-0.4	0.0	-1.2	-0.9
Hair Pigment	0.1	3.3	19.5	0.8	-4.4	2.5	1.8	-0.6	1.3	0.7	1.0	0.3	-0.3
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.4	0.1	-0.2	-0.6	0.3	0.3	0.6	0.5	0.1	-0.6	-0.2
Medication: Levothyroxine sodium	0.1	0.1	0.4	-0.1	-0.6	0.3	0.3	-0.2	-0.0	0.1	-0.4	0.3	-0.3
Trunk fat-free mass	0.1	0.4	1.7	-0.6	-1.3	0.6	0.1	0.2	0.3	1.0	-0.3	0.5	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.7	-0.7	0.8	0.1	0.7	-0.3	-0.3	0.2	-0.6	0.3	0.3
Trunk predicted mass	0.1	0.4	1.9	-0.6	-1.4	0.6	-0.0	0.2	0.4	1.0	-0.3	0.5	0.4
Standing height	0.1	1.5	4.4	0.9	-1.5	1.3	-1.1	1.0	1.4	2.1	1.0	0.6	-0.2
Birth weight of first child	0.1	0.2	0.9	-0.0	-0.0	0.4	-0.6	0.3	1.0	-0.3	-0.1	0.0	-0.6
Arm fat-free mass (right)	0.1	0.5	2.4	-0.1	-1.5	0.8	0.2	0.5	0.8	1.0	0.2	0.7	0.1
Arm predicted mass (right)	0.1	0.6	3.0	-0.2	-1.7	0.9	0.6	0.3	0.8	0.9	0.1	0.6	0.3
Alcohol intake frequency.	0.1	0.2	0.9	-0.4	1.0	-0.9	-0.4	-0.4	-0.2	0.1	-0.0	0.4	0.2
Comparative height size at age 10	0.1	0.6	2.6	0.4	-0.3	0.7	-0.6	1.3	0.8	1.6	0.4	-0.3	-0.0
Whole body fat-free mass	0.1	0.8	3.0	-0.2	-1.7	1.1	0.2	0.5	0.7	1.3	0.2	1.0	0.2
Qualifications: nursing, teaching	0.1	0.1	0.5	0.0	0.5	-0.4	-0.1	0.7	-0.3	-0.4	0.2	-0.2	0.5
Whole body water mass	0.1	0.7	3.3	-0.2	-1.8	1.0	0.2	0.5	0.6	1.3	0.2	0.9	0.1
Irritability	0.1	0.1	0.4	-0.1	-0.5	0.3	0.6	-0.2	-0.3	-0.0	0.6	0.4	-0.1
Risk taking	0.1	0.2	0.6	-0.4	0.8	0.2	0.6	-0.4	-0.2	-0.4	-0.5	-0.4	0.5
Pain experienced in last month	0.1	0.2	0.9	0.2	-0.4	0.7	-0.9	0.1	0.2	0.0	-0.3	0.0	-0.1
Arm predicted mass (left)	0.1	0.6	3.3	-0.2	-1.8	0.7	0.3	0.4	0.7	1.2	0.2	0.4	0.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.5	1.3	-0.8	1.1	-0.4	-0.6	-0.8	-0.6	-0.7	-0.5	1.1	-0.3
Chronic bronchitis/emphysema (father)	0.0	0.0	0.1	-0.2	0.1	-0.0	0.3	0.3	0.1	0.1	0.4	-0.2	-0.0
Had other major operations	0.0	0.0	0.3	-0.1	-0.2	-0.0	-0.5	0.1	-0.1	0.2	-0.0	0.2	-0.0

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