Best TWAS P=5.59e-10 · Best GWAS P=3.03e-13 conditioned to 1.49e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | WNT2B | 0.06 | 0.02 | lasso | 7 | 0.03 | 0.00094 | -4.6 | -5.4 | 7.3e-08 | -0.14 | 0.56 | 0.02 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CTTNBP2NL | 0.04 | 0.00 | blup | 53 | 0.02 | 0.00211 | -5.7 | -5.6 | 2.8e-08 | -0.27 | 0.03 | 0.19 | TRUE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | WNT2B | 0.05 | 0.02 | blup | 46 | 0.05 | 0.00047 | -4.5 | -5.1 | 3.1e-07 | -0.30 | 0.06 | 0.10 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | RHOC | 0.04 | 0.03 | enet | 9 | 0.04 | 0.00014 | -5.5 | -6.2 | 5.6e-10 | -0.30 | 0.01 | 0.96 | TRUE |