[Hub]/) : Traits : BMI :

chr9:13,891,813-16,758,776

Best TWAS P=7.43e-28 · Best GWAS P=6.15e-24 conditioned to 0.187

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CCDC171 0.18 0.05 lasso 5 0.08 2.2e-05 -4.3 -6.0 1.7e-09 0.32 0.33 0.08 FALSE
2 GTEx Artery Tibial CCDC171 0.10 0.09 enet 9 0.12 7.2e-10 5.1 -7.0 2.4e-12 0.62 0.82 0.18 FALSE
3 GTEx Artery Tibial RP11-408A13.4 0.22 0.08 lasso 10 0.12 1.0e-09 4.8 5.7 1.2e-08 0.00 0.93 0.07 FALSE
4 GTEx Brain Caudate basal ganglia CCDC171 0.30 0.18 lasso 4 0.23 2.4e-07 9.4 -9.9 4.1e-23 0.96 0.09 0.91 FALSE
5 GTEx Brain Caudate basal ganglia RP11-408A13.4 0.30 0.17 lasso 9 0.16 2.5e-05 5.5 6.0 1.4e-09 0.03 0.21 0.11 TRUE
6 GTEx Brain Cerebellar Hemisphere CCDC171 0.46 0.19 lasso 7 0.23 1.3e-06 -9.5 -10.9 7.4e-28 0.88 0.19 0.77 TRUE
7 GTEx Brain Cerebellar Hemisphere RP11-408A13.4 0.71 0.05 lasso 20 0.13 4.0e-04 4.8 5.5 4.2e-08 0.04 0.13 0.12 FALSE
8 GTEx Brain Cerebellum CCDC171 0.46 0.22 lasso 7 0.15 3.4e-05 -10.0 -10.1 5.5e-24 0.97 0.06 0.93 FALSE
9 GTEx Brain Cortex CCDC171 0.26 0.15 lasso 2 0.16 2.8e-05 -7.9 -9.1 6.4e-20 0.91 0.16 0.75 FALSE
10 GTEx Brain Frontal Cortex BA9 CCDC171 0.27 0.18 enet 10 0.19 8.3e-06 9.2 -9.2 2.7e-20 0.86 0.09 0.84 FALSE
11 GTEx Brain Hypothalamus CCDC171 0.32 0.17 enet 6 0.09 4.0e-03 -9.5 -8.4 6.5e-17 0.88 0.12 0.58 FALSE
12 GTEx Breast Mammary Tissue CCDC171 0.21 0.01 lasso 5 0.03 1.5e-02 8.2 -5.9 3.8e-09 0.55 0.36 0.21 FALSE
13 GTEx Esophagus Gastroesophageal Junction RP11-408A13.4 0.30 0.16 lasso 3 0.09 3.1e-04 5.4 5.3 9.6e-08 0.01 0.24 0.17 FALSE
14 GTEx Lung CCDC171 0.13 0.03 enet 9 0.01 5.0e-02 5.3 -7.4 1.1e-13 0.71 0.34 0.46 FALSE
15 GTEx Nerve Tibial CCDC171 0.25 0.16 lasso 6 0.14 2.1e-10 -9.4 -9.5 1.7e-21 0.95 0.27 0.73 FALSE
16 GTEx Ovary CCDC171 0.21 0.19 lasso 4 0.16 7.7e-05 8.8 8.4 3.5e-17 -0.89 0.11 0.66 FALSE
17 GTEx Pituitary CCDC171 0.28 0.16 enet 29 0.12 5.2e-04 8.6 -9.3 1.2e-20 0.90 0.25 0.66 FALSE
18 GTEx Prostate RP11-408A13.4 0.30 0.03 lasso 7 0.05 2.1e-02 4.5 5.5 3.7e-08 0.02 0.15 0.10 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic CCDC171 0.20 0.04 enet 45 0.06 4.9e-04 9.0 -5.5 3.1e-08 0.41 0.65 0.24 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic RP11-408A13.4 0.26 0.05 lasso 6 0.10 6.4e-06 4.8 5.2 2.2e-07 0.00 0.87 0.06 FALSE
21 GTEx Skin Sun Exposed Lower leg CCDC171 0.14 0.09 enet 13 0.12 1.9e-10 8.8 -6.8 1.0e-11 0.65 0.96 0.04 FALSE
22 GTEx Stomach RP11-408A13.4 0.32 0.26 lasso 7 0.25 3.1e-12 4.8 5.1 2.9e-07 0.00 0.95 0.05 FALSE
23 METSIM Adipose CCDC171 0.03 0.00 blup 828 0.01 4.0e-02 9.1 -8.1 6.3e-16 0.80 0.20 0.58 FALSE
24 ROSMAP Brain Pre-frontal Cortex CCDC171 0.14 0.11 enet 21 0.11 8.3e-14 9.5 -8.7 4.1e-18 0.84 0.78 0.22 FALSE
25 The Cancer Genome Atlas Soft Tissue Sarcoma C9orf93 0.06 0.05 lasso 3 0.03 5.3e-03 8.2 -7.3 3.9e-13 0.69 0.13 0.28 FALSE