Best TWAS P=1.89e-07 · Best GWAS P=2.07e-09 conditioned to 0.00256
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | ANKRD26 | 0.16 | 0.13 | lasso | 4 | 0.14 | 4.2e-18 | 5.7 | 5.2 | 1.9e-07 | 0.91 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | MASTL | 0.22 | 0.06 | blup | 61 | 0.08 | 4.2e-03 | 5.9 | -5.2 | 2.3e-07 | -0.75 | 0.01 | 0.81 | FALSE |