[Hub]/) : Traits : BMI :

chr10:64,195,778-66,034,105

Best TWAS P=6.25e-11 · Best GWAS P=2.36e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex REEP3 0.05 0.05 lasso 3 0.04 5.9e-06 -6.1 -6.5 6.7e-11 -0.95 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous REEP3 0.10 0.03 lasso 3 0.03 7.2e-04 5.4 -5.3 1.2e-07 -0.64 0.37 0.36 FALSE
3 GTEx Brain Cortex NRBF2 0.30 0.26 enet 24 0.21 1.4e-06 5.6 6.4 1.8e-10 0.95 0.02 0.97 FALSE
4 GTEx Brain Frontal Cortex BA9 NRBF2 0.25 0.17 lasso 6 0.16 6.1e-05 -6.2 6.5 6.3e-11 0.96 0.02 0.97 TRUE
5 GTEx Cells Transformed fibroblasts JMJD1C 0.09 0.01 enet 18 0.07 8.6e-06 4.9 5.4 7.5e-08 0.61 0.13 0.68 FALSE
6 GTEx Esophagus Mucosa NRBF2 0.14 0.11 lasso 10 0.11 6.4e-08 -6.1 6.1 1.0e-09 0.89 0.07 0.93 FALSE
7 GTEx Nerve Tibial NRBF2 0.08 0.09 enet 11 0.06 5.0e-05 -6.1 5.7 1.2e-08 0.88 0.05 0.95 FALSE
8 GTEx Stomach NRBF2 0.09 0.04 lasso 6 0.03 1.6e-02 4.1 5.8 4.9e-09 0.78 0.06 0.55 FALSE
9 GTEx Testis NRBF2 0.14 0.08 lasso 12 0.09 6.7e-05 -6.1 6.4 1.6e-10 0.92 0.07 0.92 FALSE
10 NTR Blood NRBF2 0.03 0.01 bslmm 386 0.01 3.4e-05 -2.5 -5.2 2.1e-07 -0.51 0.12 0.42 FALSE
11 ROSMAP Brain Pre-frontal Cortex NRBF2 0.34 0.46 lasso 5 0.46 3.1e-66 -6.2 6.4 1.3e-10 0.94 0.06 0.94 FALSE
12 ROSMAP Brain Pre-frontal Cortex REEP3 0.10 0.11 lasso 8 0.09 7.2e-12 5.3 -5.8 7.8e-09 -0.75 0.86 0.14 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma NRBF2 0.05 0.06 lasso 2 0.06 5.5e-12 -6.2 6.1 1.1e-09 0.89 0.00 1.00 FALSE
14 The Cancer Genome Atlas Glioblastoma Multiforme JMJD1C 0.11 0.02 blup 87 0.05 1.4e-02 -6.2 5.2 2.6e-07 0.79 0.01 0.71 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NRBF2 0.04 0.04 enet 5 0.03 1.3e-04 -6.2 6.4 1.2e-10 0.91 0.00 0.99 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NRBF2 0.10 0.06 lasso 7 0.08 3.5e-09 5.5 6.4 1.2e-10 0.86 0.01 0.99 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma NRBF2 0.08 0.08 enet 6 0.08 4.3e-09 -6.2 6.1 1.0e-09 0.90 0.00 1.00 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma REEP3 0.04 0.04 blup 59 0.05 1.8e-06 5.1 -5.5 4.4e-08 -0.80 0.06 0.93 FALSE
19 The Cancer Genome Atlas Lung Adenocarcinoma NRBF2 0.09 0.06 enet 8 0.07 2.7e-08 -6.2 5.2 1.7e-07 0.82 0.00 1.00 FALSE
20 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NRBF2 0.09 0.02 enet 6 0.04 1.4e-05 2.7 5.4 7.8e-08 0.74 0.06 0.91 FALSE
21 The Cancer Genome Atlas Pancreatic Adenocarcinoma NRBF2 0.18 0.13 enet 11 0.08 2.5e-04 -6.2 6.0 1.8e-09 0.82 0.00 0.99 FALSE
22 The Cancer Genome Atlas Prostate Adenocarcinoma JMJD1C 0.04 0.01 blup 88 0.01 9.7e-03 -6.2 6.2 7.2e-10 0.80 0.01 0.90 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma NRBF2 0.08 0.09 lasso 6 0.08 9.7e-09 -6.2 6.4 2.0e-10 0.91 0.00 1.00 FALSE
24 The Cancer Genome Atlas Thyroid Carcinoma NRBF2 0.14 0.10 enet 16 0.09 8.1e-09 -6.2 5.8 5.1e-09 0.86 0.00 1.00 FALSE