Best TWAS P=5.22e-11 · Best GWAS P=1.41e-14 conditioned to 3.42e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | TCF7L2 | 0.19 | 0.09 | lasso | 6 | 0.05 | 0.0010 | -6.7 | 6.6 | 5.2e-11 | -0.69 | 0.17 | 0.81 | TRUE |
| 2 | NTR | Blood | VTI1A | 0.02 | 0.00 | blup | 610 | 0.00 | 0.0113 | -1.6 | 6.3 | 3.2e-10 | -0.40 | 0.04 | 0.13 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | TDRD1 | 0.06 | 0.02 | bslmm | 509 | 0.02 | 0.0014 | -1.7 | -5.1 | 3.0e-07 | 0.04 | 0.03 | 0.96 | TRUE |