[Hub]/) : Traits : BMI : ← →

chr12:53,075,660-55,370,164

Best TWAS P=4.58e-11 · Best GWAS P=8.46e-12 conditioned to 0.0339

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PRR13 0.13 0.10 lasso 7 0.09 9.2e-08 5.0 -5.2 2.3e-07 -0.04 0.86 0.13 FALSE
2 GTEx Breast Mammary Tissue SP1 0.12 0.13 lasso 5 0.08 9.5e-05 4.8 5.3 1.2e-07 0.06 0.83 0.12 FALSE
3 GTEx Esophagus Gastroesophageal Junction PRR13 0.22 0.16 lasso 4 0.18 3.2e-07 5.0 -5.7 1.6e-08 -0.05 0.27 0.10 FALSE
4 GTEx Skin Sun Exposed Lower leg SP1 0.13 0.10 lasso 3 0.13 1.1e-10 4.7 5.2 2.4e-07 0.04 0.69 0.31 FALSE
5 YFS Blood CBX5 0.02 0.01 lasso 3 0.02 2.0e-07 -6.8 -6.5 1.1e-10 0.82 0.01 0.99 FALSE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRR13 0.13 0.04 blup 28 0.07 3.3e-06 4.1 -5.9 2.9e-09 0.01 0.07 0.40 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PRR13 0.05 0.03 blup 28 0.04 4.1e-03 5.0 -5.5 2.9e-08 -0.04 0.03 0.05 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma PRR13 0.07 0.04 blup 28 0.05 4.7e-06 5.0 -5.8 5.9e-09 -0.05 0.36 0.29 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma SMUG1 0.08 0.05 enet 13 0.06 3.8e-07 2.4 5.2 1.6e-07 -0.54 0.06 0.02 FALSE
10 The Cancer Genome Atlas Rectum Adenocarcinoma CBX5 0.16 0.10 lasso 4 0.11 1.5e-03 -6.8 -6.6 4.6e-11 0.92 0.01 0.71 TRUE
11 The Cancer Genome Atlas Rectum Adenocarcinoma PCBP2 0.25 0.04 blup 36 0.10 2.3e-03 -6.3 -5.9 3.2e-09 -0.04 0.00 0.62 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma PCBP2 0.04 0.01 enet 6 0.02 4.8e-03 3.7 -6.0 1.5e-09 -0.01 0.01 0.38 TRUE