Best TWAS P=5.65e-11 · Best GWAS P=1.36e-09 conditioned to 0.129
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FARP1 | 0.10 | 0.05 | enet | 5 | 0.05 | 1.4e-06 | -5.8 | 5.9 | 4.6e-09 | -0.65 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | STK24 | 0.18 | 0.06 | lasso | 8 | 0.08 | 2.4e-07 | -4.9 | -5.6 | 1.9e-08 | 0.65 | 0.04 | 0.96 | FALSE |
| 3 | GTEx | Esophagus Mucosa | FARP1-AS1 | 0.11 | 0.03 | lasso | 2 | 0.04 | 1.7e-03 | -5.8 | -5.9 | 2.7e-09 | 0.70 | 0.01 | 0.98 | FALSE |
| 4 | NTR | Blood | FARP1 | 0.02 | 0.01 | lasso | 3 | 0.01 | 4.3e-04 | -5.7 | -6.6 | 5.6e-11 | 0.78 | 0.02 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | STK24 | 0.04 | 0.03 | lasso | 6 | 0.04 | 5.3e-05 | 5.5 | 5.5 | 3.5e-08 | -0.58 | 0.10 | 0.87 | FALSE |