Best TWAS P=5.6e-09 · Best GWAS P=2.82e-09 conditioned to 0.0309
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | FAM177A1 | 0.13 | 0.04 | enet | 18 | 0.07 | 5.5e-06 | -5.5 | 5.6 | 2.8e-08 | -0.96 | 0.02 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | BAZ1A | 0.07 | 0.04 | enet | 14 | 0.03 | 5.6e-07 | -5.7 | -5.8 | 5.6e-09 | 0.79 | 0.00 | 1.00 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA0391 | 0.12 | 0.11 | enet | 14 | 0.14 | 2.0e-13 | -5.3 | 5.3 | 1.4e-07 | -0.68 | 0.15 | 0.85 | FALSE |