Hub : Genes

FAM177A1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0720 0.0250 5.4e-05 0.053 0.040 0.040 0.042 0.037 4.5e-07 1.1e-05 1.1e-05 7.3e-06 2.2e-05
2 GTEx Adipose Subcutaneous 0.1900 0.0480 9.5e-08 0.063 NA 0.049 NA 0.109 7.3e-06 NA 6.6e-05 NA 3.6e-09
3 GTEx Adrenal Gland 0.1725 0.0757 4.6e-03 0.068 NA 0.043 NA 0.041 1.9e-03 NA 1.2e-02 NA 1.3e-02
4 GTEx Artery Tibial 0.0705 0.0316 4.3e-03 0.071 NA 0.074 NA 0.067 3.2e-06 NA 2.1e-06 NA 5.7e-06
5 GTEx Brain Cerebellum 0.1340 0.0600 9.4e-03 0.041 NA -0.006 NA 0.044 2.3e-02 NA 5.5e-01 NA 1.9e-02
6 GTEx Brain Frontal Cortex BA9 0.2200 0.0761 2.2e-03 0.029 NA 0.024 NA 0.056 5.9e-02 NA 7.8e-02 NA 1.3e-02
7 GTEx Cells Transformed fibroblasts 0.3190 0.0620 3.2e-11 0.201 NA 0.215 NA 0.201 5.4e-15 NA 4.7e-16 NA 5.1e-15
8 GTEx Colon Transverse 0.1980 0.0780 7.0e-03 0.023 NA -0.004 NA 0.009 2.7e-02 NA 5.4e-01 NA 1.1e-01
9 GTEx Esophagus Mucosa 0.3250 0.0680 1.5e-08 0.130 NA 0.136 NA 0.138 5.2e-09 NA 2.2e-09 NA 1.7e-09
10 GTEx Heart Left Ventricle 0.0914 0.0432 9.8e-03 0.025 NA 0.056 NA 0.063 1.7e-02 NA 6.0e-04 NA 2.8e-04
11 GTEx Muscle Skeletal 0.1610 0.0373 8.4e-12 0.086 NA 0.154 NA 0.135 8.4e-09 NA 6.0e-15 NA 3.6e-13
12 GTEx Nerve Tibial 0.2286 0.0544 2.8e-08 0.071 NA 0.102 NA 0.096 9.3e-06 NA 1.1e-07 NA 2.7e-07
13 GTEx Skin Not Sun Exposed Suprapubic 0.1710 0.0580 7.2e-04 0.032 NA 0.044 NA 0.026 6.8e-03 NA 2.0e-03 NA 1.4e-02
14 GTEx Skin Sun Exposed Lower leg 0.1880 0.0490 1.8e-07 0.043 NA 0.087 NA 0.098 1.7e-04 NA 1.2e-07 NA 1.7e-08
15 GTEx Testis 0.3000 0.0670 3.6e-08 0.155 NA 0.173 NA 0.232 2.2e-07 NA 3.8e-08 NA 1.2e-10
16 GTEx Thyroid 0.1310 0.0390 1.8e-06 0.040 NA 0.069 NA 0.057 5.0e-04 NA 5.5e-06 NA 3.5e-05
17 GTEx Whole Blood 0.1570 0.0450 1.6e-05 0.088 NA 0.069 NA 0.088 1.8e-08 NA 6.5e-07 NA 1.8e-08
18 METSIM Adipose 0.0466 0.0201 1.2e-03 0.014 0.015 0.011 0.017 0.015 3.1e-03 1.9e-03 7.6e-03 1.3e-03 2.2e-03
19 NTR Blood 0.0211 0.0088 7.3e-04 0.002 0.009 0.001 0.008 0.003 5.1e-02 6.0e-04 1.1e-01 7.5e-04 4.1e-02
20 YFS Blood 0.0880 0.0211 1.1e-15 0.074 0.062 0.070 0.072 0.072 4.6e-23 2.0e-19 9.0e-22 1.5e-22 1.6e-22
21 TCGA Kidney Renal Clear Cell Carcinoma 0.0348 0.0171 6.7e-04 0.020 0.031 0.009 NA 0.020 2.2e-03 2.0e-04 2.8e-02 NA 2.3e-03
22 TCGA Ovarian Serous Cystadenocarcinoma 0.0810 0.0440 4.1e-03 -0.001 0.023 0.018 NA 0.009 3.6e-01 1.0e-02 2.1e-02 NA 7.1e-02
23 TCGA Thyroid Carcinoma 0.0680 0.0300 3.4e-06 0.074 0.059 0.057 NA 0.059 1.0e-07 2.1e-06 2.8e-06 NA 2.2e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bipolar Disorder (2018) 0.9 1.5 5.3 -2.0 -0.1 -0.8 -1.1 -1.4 1.2 1.0 0.6 1.8 -0.5 0.9 -1.2 0.2 -0.7 1.5 -0.9 1.9 -0.3 1.3 1.5 -0.9 2.3 -0.0
Bipolar Disorder or Schizophrenia 1.3 3.1 8.1 -0.5 -1.1 -2.5 -0.9 -1.5 1.9 0.6 2.7 1.3 -2.8 -2.4 -2.5 0.1 -1.7 1.9 0.2 2.1 0.7 2.2 2.2 0.0 0.5 2.4
Depressed Affect (Nagel 2018) 0.3 0.6 3.2 1.8 0.3 0.6 0.9 0.4 1.1 0.2 1.3 0.4 -0.7 -0.8 -0.7 0.2 0.0 -0.4 1.3 0.3 0.4 0.2 0.5 0.3 -0.4 0.8
Depression (Nagel 2018) 1.4 2.2 8.7 2.8 1.4 -0.3 2.0 1.7 0.3 0.7 2.9 0.9 -0.9 -1.8 -0.4 1.0 0.9 -0.7 2.4 0.8 0.7 -0.7 1.1 1.7 -0.5 2.2
Intelligence (Savage-Jansen 2018) 0.4 1.3 4.6 -2.2 -2.1 -1.0 -1.5 -1.2 -1.2 0.5 -0.4 0.1 -1.2 -0.2 -1.1 -1.7 -1.6 1.0 -0.6 0.3 -1.2 -0.2 0.4 -1.3 -1.0 0.2
Neuroticism (Nagel 2018) 0.3 0.7 3.9 1.3 0.4 0.7 1.5 0.1 2.0 -0.0 1.2 0.9 -0.7 -0.2 -0.9 0.5 0.2 -0.8 0.7 0.3 0.5 1.1 0.3 0.7 0.6 0.7
Schizophrenia (2018) 1.6 3.3 14.9 1.0 -1.4 -2.6 -0.3 -0.8 1.4 -0.0 3.0 0.2 -3.3 -3.9 -2.1 -0.0 -1.6 1.2 1.1 1.2 1.2 1.8 1.5 0.8 -1.2 3.1
Schizophrenia vs Biploar Disorder 1.5 2.0 7.9 -0.5 -2.3 -2.8 -0.9 -0.7 2.3 -1.0 1.1 -1.0 -1.5 -1.9 -2.0 -1.2 -2.2 0.7 -0.6 -0.4 0.5 0.7 -0.2 -0.1 -1.6 1.5
Worry (Nagel 2018) 0.3 0.7 2.6 1.2 0.7 1.3 1.5 0.1 1.6 0.3 0.7 1.1 0.2 0.2 -0.7 0.4 0.3 -0.9 0.8 0.0 0.4 1.0 0.2 0.6 1.0 0.0
Alzheimer’s Disease (in mother) 2.0 2.4 7.4 2.3 0.8 0.3 1.0 2.1 -0.1 -2.1 1.0 -1.7 -0.7 -0.5 2.2 0.0 1.1 -2.7 1.0 -2.3 -0.4 -1.4 -2.1 1.6 -2.2 0.8
Alzheimer’s Disease (in father) 1.9 2.1 7.1 1.6 0.1 -1.1 1.6 1.7 0.5 -0.4 2.5 0.2 -2.0 -2.2 -0.3 0.8 1.2 -0.2 2.7 0.4 1.0 0.6 0.7 1.6 -1.6 2.6
Alzheimer’s Disease (including proxy) 1.2 1.7 5.6 2.1 0.6 0.4 1.3 2.4 -0.5 -0.8 1.3 -0.7 -1.1 -0.6 1.2 0.3 1.6 -1.9 2.1 -1.1 -0.1 -1.0 -0.8 1.3 -2.2 1.1
Crohns Disease (2017) 2.0 4.5 15.7 2.0 -1.8 -3.5 1.3 0.5 2.9 -0.2 3.0 -0.5 -2.7 -4.0 0.2 -1.9 -1.3 -0.5 2.5 -1.6 -0.4 -1.6 -0.1 1.4 -3.1 3.3
Irritable Bowel Disease (IBD) 2.4 5.6 19.0 2.5 -1.8 -3.3 1.6 0.7 3.2 -0.2 3.6 -0.5 -3.7 -4.4 0.5 -1.5 -0.7 -0.2 3.2 -1.2 0.1 -1.9 0.4 1.5 -3.9 3.6
Ulcerative Colitis (UC) 1.7 3.3 10.5 2.0 -0.9 -1.6 1.4 1.0 2.5 0.0 2.8 -0.3 -3.2 -3.2 0.6 -0.6 0.2 0.2 2.9 -0.5 0.4 -1.2 0.8 1.1 -3.2 2.6
Major Depression (MDD) 1.0 1.3 4.3 1.8 0.6 -1.0 1.1 0.6 -0.0 -0.1 1.6 0.3 -1.9 -1.8 0.3 0.6 0.3 -0.5 1.7 -0.1 2.1 0.1 0.1 1.5 -0.3 1.9
Reaction Time 0.3 0.6 2.2 0.9 0.7 -0.2 1.2 0.2 0.3 0.5 0.9 1.3 -0.6 -1.5 0.5 0.6 0.8 -0.7 1.2 0.4 0.5 1.0 0.4 0.8 0.6 0.9
Verbal and Numeric Reasoning (VNR) 0.5 1.3 3.2 -0.9 -1.8 -1.0 -1.1 -1.3 -1.6 1.3 -0.7 -0.5 -1.1 -0.5 -0.8 -1.7 -0.6 1.3 0.2 0.7 -1.5 -1.5 1.0 -1.2 -1.5 0.1
Breast Cancer 2.4 5.8 19.5 -2.8 0.4 3.9 -1.5 -1.7 -1.5 2.2 -4.0 -0.2 3.9 3.4 -0.4 -1.0 -0.6 2.0 -2.7 0.8 -2.2 -0.7 0.3 -3.3 2.3 -4.4
Ovarian Cancer 1.5 2.0 5.5 -2.3 -1.2 0.7 -1.2 -1.8 -0.7 1.4 -1.4 0.9 0.5 1.0 -2.2 -1.3 -1.7 1.9 -1.3 1.2 -1.3 0.5 1.0 -2.4 0.5 -1.7
Prostate Cancer 0.5 0.7 5.5 -0.1 -0.1 -0.5 -0.4 -0.3 -2.4 -0.8 -0.6 -1.5 0.1 0.7 0.6 0.4 0.0 -0.8 -0.7 -1.3 0.4 -1.2 -1.3 0.1 -0.3 -0.9
Age at First Birth 0.6 0.9 2.9 -0.8 -1.3 -0.4 -0.4 -1.2 -0.7 1.0 0.1 0.0 -0.5 -1.1 -1.5 -1.6 -1.1 1.0 -0.1 0.2 -1.7 -1.2 0.6 -1.2 -0.2 -0.2
Bipolar Disorder (2011) 0.9 0.8 3.7 -0.1 -0.2 -0.6 -0.8 -1.1 1.9 1.2 0.8 0.9 -0.3 -0.7 -0.8 -0.3 -0.6 1.2 0.3 1.4 -0.9 0.5 1.7 -0.5 1.1 0.5
Body Mass Index (BMI) (2010) 0.9 1.3 3.9 1.1 2.0 1.4 0.5 1.4 -1.8 -1.4 -0.1 -0.4 1.6 -0.0 1.4 1.4 1.2 -1.3 0.8 -0.6 0.7 1.2 -1.1 0.9 0.7 -0.1
Coronary Artery Disease (CAD) 0.6 0.7 2.8 1.0 0.4 0.8 0.9 1.4 0.4 -0.9 0.8 -0.2 0.0 0.9 1.0 0.4 0.0 -1.7 0.1 -1.4 0.6 -0.7 -1.3 0.8 -0.4 0.1
Crohns Disease (2012) 1.6 2.6 9.9 0.9 -1.4 -2.5 0.6 -1.1 2.1 1.9 1.6 1.6 -1.9 -3.2 -1.1 -1.3 -1.0 1.6 1.9 1.2 -1.2 -0.1 2.3 -0.1 -0.5 1.9
Mean Putamen Volume 1.9 2.1 7.3 -1.1 -0.8 -0.3 -1.6 -1.7 -0.9 2.3 0.6 1.5 0.2 -0.2 -2.2 -1.0 -1.6 2.1 -0.8 2.4 -1.4 1.0 2.7 -1.4 1.4 -0.0
Fasting Glucose 0.6 0.7 5.2 -1.3 -0.8 0.4 -0.9 -2.3 0.3 -0.5 -0.6 0.0 0.6 0.3 -0.6 -0.5 -0.5 0.5 -0.9 0.1 -0.7 1.5 -0.3 -0.6 0.6 -0.7
HbA1C 0.2 0.2 1.0 0.2 0.3 0.8 0.5 0.7 0.2 0.2 0.9 0.7 0.6 0.6 -0.6 -0.3 -0.2 -0.1 -0.0 -0.4 0.3 -1.0 -0.1 -0.0 0.3 0.1
HDL Cholesterol 0.6 1.0 2.7 0.5 1.1 -0.0 1.5 0.8 1.0 0.4 1.3 1.0 -0.2 -1.6 0.5 1.2 1.2 0.0 1.6 0.9 0.9 -0.1 0.8 1.3 0.1 1.2
LDL Cholesterol 0.5 0.8 2.3 -0.6 -1.5 -0.8 -0.5 -0.8 -1.0 1.3 0.0 1.1 -0.6 0.5 -1.3 -1.2 -0.9 0.9 -0.2 0.5 -1.5 -0.4 1.1 -1.2 -0.5 -0.2
Lupus 1.1 1.7 8.0 -0.1 0.4 1.0 1.0 -0.2 1.1 2.4 1.7 2.8 -0.6 -1.4 -0.2 -0.4 0.6 0.4 2.2 1.3 -1.7 -0.2 2.1 0.2 0.7 0.7
Neuroticism (2016) 1.2 1.7 8.0 2.2 -0.5 -1.1 1.3 0.4 1.0 0.7 2.5 0.7 -1.6 -2.8 -0.4 -0.1 -0.2 -0.5 1.9 0.3 -0.5 -0.3 0.8 1.2 -1.0 2.2
Primary Biliary Cirrhosis 3.2 4.6 12.4 -0.7 -2.9 -1.4 -1.8 -2.7 1.4 2.4 1.4 1.5 -2.6 -2.5 -2.6 -2.2 -2.1 3.2 0.8 2.9 -2.3 1.5 3.5 -1.8 -0.4 1.0
Rheumatoid Arthritis 1.7 2.3 8.0 1.7 2.8 2.4 2.1 1.7 -0.8 -0.2 -0.2 0.0 1.4 1.4 2.0 2.0 2.6 -1.6 0.7 -0.2 1.8 -0.6 -0.6 1.5 0.9 -0.7
Schizophrenia (2014) 2.0 4.5 12.6 -0.4 -2.3 -3.5 -0.9 -2.0 1.4 0.4 3.0 1.1 -3.5 -3.4 -3.2 -0.1 -2.3 2.1 0.3 2.0 1.0 2.4 1.9 0.2 -0.5 3.0
Triglycerides 0.1 0.2 1.0 -0.2 -0.3 -0.0 -0.1 -0.1 -0.5 -0.1 -1.0 -0.5 0.6 0.1 -0.6 0.1 0.4 0.4 -0.1 0.1 -0.8 0.5 -0.0 -0.6 -0.3 -0.8
Type 2 Diabetes (T2D) (2012) 0.2 0.2 2.6 -0.1 -0.2 0.7 -0.5 0.3 -1.6 0.2 0.7 -0.2 0.4 -0.1 -0.7 -0.1 -0.5 0.5 0.0 -0.1 0.5 -0.1 0.1 -0.3 0.1 0.1
Ulcerative Colitis 1.2 1.7 7.3 0.6 -1.5 -0.9 0.0 -0.9 2.7 1.2 1.6 1.1 -2.5 -1.9 -0.6 -0.7 -0.5 1.5 1.4 1.2 0.2 0.1 2.0 -0.3 -1.0 1.4
Blood Eosinophil Count 0.9 6.9 34.8 0.5 -0.1 2.2 -0.5 1.5 -5.4 0.9 -3.7 -3.2 2.0 4.2 1.1 -1.5 -0.3 -0.3 -2.4 -1.9 0.6 -5.9 -1.2 -2.3 -1.1 -4.4
Blood Platelet Count 0.1 0.6 2.9 1.4 0.9 0.3 1.4 0.8 0.9 0.3 0.0 -0.5 1.0 0.3 -0.4 1.7 0.4 -0.1 -0.2 0.8 1.5 0.3 0.5 0.6 0.4 0.1
Blood Red Count 1.0 9.8 24.9 -3.2 -3.4 -1.3 -2.8 -4.7 -4.9 5.0 -2.6 2.9 -0.2 0.8 -2.0 -4.1 -3.4 2.6 -2.2 2.0 -4.4 -1.5 2.8 -4.2 1.9 -2.7
Blood White Count 1.7 12.5 43.9 -1.4 -6.6 -5.4 -4.9 -2.9 -2.9 0.2 -1.5 -3.6 -3.4 -1.2 -3.3 -5.0 -6.6 3.7 -3.2 -0.5 -1.9 -0.8 0.5 -3.8 -4.7 0.1
Heel T-Score 2.2 17.1 79.7 -3.2 -4.5 -1.6 -3.8 -1.9 -4.6 2.6 -2.5 -1.7 1.7 3.9 -1.1 -7.7 -5.9 -0.6 -3.7 -4.1 -6.4 -8.9 -1.6 -4.6 -2.3 -3.6
BMI 1.2 6.7 30.9 4.8 3.0 1.3 3.0 4.4 -0.3 0.3 2.0 -0.9 -0.2 -3.1 2.8 2.3 3.3 -1.5 5.6 -0.9 0.9 -2.6 0.4 2.3 -2.2 1.7
Height 0.3 5.8 32.5 -2.5 1.9 2.5 -1.3 -2.0 -1.6 1.8 -1.6 3.3 3.7 1.6 -1.3 0.9 1.2 0.3 -0.4 3.1 -3.0 2.8 1.6 -1.8 5.7 -2.7
Waist Hip Ratio (WHR) 0.7 3.4 8.0 1.5 1.3 2.2 0.7 1.4 0.5 -2.7 -2.2 -2.8 1.8 2.5 2.4 1.4 1.1 -2.0 -1.6 -2.4 1.9 0.4 -2.8 0.6 -0.4 -1.6
Systolic Blood Pressure 0.5 2.7 9.5 1.9 -3.0 -2.0 -1.0 -0.0 -0.2 0.0 0.7 -1.9 -2.6 -1.1 -0.9 -2.4 -2.2 0.5 -0.8 -1.1 -0.8 -2.7 0.5 -1.2 -3.1 0.3
Smoking Status 0.8 1.9 7.2 1.4 -0.5 -2.5 -0.4 0.3 0.7 0.5 1.8 0.2 -1.8 -2.7 -0.3 -0.5 -0.0 1.5 1.8 1.3 -0.5 1.2 1.9 0.4 -1.4 2.5
Allergy or Eczema 3.5 9.3 42.0 -3.1 2.9 4.2 0.8 -0.7 -3.0 1.2 -4.7 1.7 4.8 6.5 0.2 2.4 1.7 -0.5 -3.1 0.9 0.6 -1.1 -0.7 -1.6 5.2 -5.0
Cardiovascular Disease 1.0 3.3 14.8 3.8 -0.6 -1.6 1.5 1.7 0.1 0.0 1.9 -1.7 -2.0 -2.2 1.2 -0.6 -0.0 -1.4 2.0 -1.7 0.5 -2.9 -0.3 1.3 -3.5 1.8
Hypothyroidism (self reported) 1.7 3.9 14.1 3.1 -1.7 -2.7 0.2 0.6 0.0 -1.4 1.7 -2.5 -3.7 -3.3 -0.9 -0.9 -0.7 0.3 1.4 -1.1 1.4 1.0 -0.1 1.3 -3.8 3.2
Respiratory disease 0.6 1.4 6.8 0.2 0.5 0.7 0.9 0.4 -2.4 0.8 -2.6 -0.6 1.6 1.6 0.5 1.2 1.2 1.1 -0.7 0.4 1.2 -1.3 0.3 -0.7 0.2 -1.4
Type 2 Diabetes (T2D) (2018) 1.3 2.5 14.5 1.3 -1.0 -0.7 -0.4 1.4 -1.9 -2.3 0.5 -2.8 -0.4 -0.9 0.8 -1.0 -0.7 -1.3 0.4 -3.0 -0.8 -1.3 -2.2 0.3 -3.8 0.5
Lung FEV1/FVC ratio 0.3 1.8 7.4 -1.5 0.5 1.0 -0.7 -1.5 1.0 -1.2 -1.7 1.2 1.2 1.7 0.8 1.1 0.3 -0.4 -0.9 0.4 -1.7 2.7 -0.7 -0.7 2.5 -1.6
Lung FVC 0.7 3.7 17.3 2.4 -0.5 -3.3 1.4 0.2 -0.2 0.6 2.8 1.4 -2.6 -4.2 -0.7 0.1 0.6 0.7 2.0 0.8 1.0 1.1 1.4 2.0 -1.9 3.7
Neuroticism 0.3 0.8 2.8 1.6 0.2 0.5 1.1 -0.3 1.2 0.3 1.1 1.0 -0.9 -0.7 -0.9 0.4 0.4 -0.1 1.1 1.0 0.1 1.7 1.0 0.5 0.3 0.8
Chronotype (morning person) 0.5 1.1 4.5 0.4 0.5 2.0 0.5 0.7 1.8 -0.7 -1.4 -1.3 0.3 0.3 2.1 0.3 1.2 -1.1 0.5 -1.2 0.2 -0.3 -1.2 0.0 -1.0 -1.2
Hair Pigment 0.1 1.6 7.1 -1.3 -2.0 -1.6 -1.6 -0.7 1.1 -1.4 -0.3 -0.8 -1.1 1.6 -0.6 -1.3 -2.4 -0.1 -2.7 -1.0 0.8 0.2 -1.0 -0.6 -0.5 0.2
Tanning 0.3 3.9 17.5 0.1 -2.5 0.4 -2.5 -0.7 -2.3 1.3 -1.5 -2.9 0.1 -1.0 -0.5 -4.2 -1.9 1.4 0.0 -1.4 -2.5 -2.6 0.0 -2.5 -3.3 -1.5
Hand grip strength (left) 0.5 1.4 8.9 1.1 0.3 0.2 0.5 0.9 -3.0 -0.2 -1.1 -1.6 0.3 -0.1 0.4 -1.2 0.7 -1.0 0.4 -1.2 -0.5 -2.8 -1.1 -0.0 -1.5 -0.8
Number of treatments/medications taken 0.7 1.2 5.8 2.2 0.2 -1.3 0.7 1.3 -0.7 -0.3 1.4 -1.0 -0.8 -0.9 0.9 -0.3 0.0 -0.4 0.9 -0.9 0.2 -1.4 -0.1 1.2 -2.4 1.4
Average weekly spirits intake 0.6 0.7 6.6 -1.2 0.5 0.7 0.0 0.5 2.6 -0.3 0.8 1.3 0.0 -0.7 -0.3 0.0 -0.5 -0.7 0.1 0.1 0.7 1.5 -0.2 0.4 1.1 0.5
Sensitivity / hurt feelings 0.8 1.3 4.6 0.6 1.0 2.1 1.2 -0.2 0.6 1.3 -0.5 1.9 0.9 0.8 -0.4 1.1 1.1 0.1 0.4 1.9 -0.5 1.0 1.3 -0.4 2.1 -1.0
Frequency of depressed mood in last 2 weeks 2.6 3.6 12.5 2.8 1.9 -0.2 2.5 2.2 1.8 -0.1 3.5 1.1 -1.0 -2.9 -0.1 1.3 1.6 -1.3 3.2 0.8 1.0 0.0 1.0 2.5 -0.2 2.9
Hearing difficulty/problems: Yes 0.3 0.4 1.3 0.6 0.4 0.5 -0.4 -0.6 0.6 0.8 -0.8 0.0 0.5 0.7 -0.3 -0.1 0.0 0.8 -0.5 1.0 -1.1 0.2 1.1 -0.8 0.4 -0.9
Relative age of first facial hair 0.6 1.2 4.4 -0.2 -0.7 0.8 -2.1 -1.7 1.4 -0.6 -0.7 -0.5 0.9 1.0 -0.6 -0.6 -1.5 1.0 -1.6 0.7 -0.7 2.1 0.3 -1.2 1.0 -0.7
Other serious medical condition/disability diagnosed by doctor 0.8 1.0 3.8 1.0 -0.4 -1.4 0.9 0.5 1.2 -0.8 1.2 -0.8 -1.6 -1.5 -0.2 0.4 -0.0 -0.8 0.8 -0.9 0.2 0.1 -0.5 1.1 -1.9 1.5
Ever used hormone-replacement therapy (HRT) 3.1 3.9 17.2 2.1 3.2 0.9 3.2 1.6 0.4 -0.6 0.7 1.3 0.7 -0.5 1.9 4.2 2.6 -0.9 1.6 0.7 3.5 2.1 0.1 2.6 1.4 1.6
Ever had hysterectomy (womb removed) 1.6 1.8 8.5 1.9 0.2 -0.3 -0.5 1.5 -0.3 -2.0 0.8 -2.9 -0.3 -0.5 0.9 0.3 -0.7 -0.8 -0.2 -1.8 2.1 -0.5 -1.7 1.3 -2.2 1.2
Systolic blood pressure, automated reading 0.8 2.2 8.1 1.3 -2.4 -1.7 -1.0 0.0 -0.4 -0.3 0.3 -1.9 -2.0 -0.8 -0.5 -2.4 -2.2 0.0 -0.7 -1.7 -0.7 -2.9 -0.2 -1.1 -2.6 0.0
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.5 -0.3 -0.1 1.5 0.6 -0.0 -1.6 0.3 0.2 1.2 0.5 -0.6 -0.5 -0.4 0.0 -0.2 0.3 -0.0 -0.9 -0.3 0.4 -0.6 -0.1 -0.7
Angina 1.3 1.7 4.6 1.7 1.3 0.9 0.6 1.3 -1.3 -1.3 -1.1 -2.1 1.3 1.1 1.8 0.4 0.9 -1.6 -0.4 -1.8 0.7 -1.7 -1.8 0.6 -0.7 -0.9
Medication for hormone replacement therapy 1.7 1.9 8.9 -0.9 1.9 2.1 1.0 0.5 1.1 -1.1 -1.0 0.5 1.8 1.8 1.4 3.0 1.1 -0.6 -0.6 -0.3 1.7 1.7 -1.3 0.7 1.3 -0.9
Vitamin and mineral supplements 1.5 2.1 11.5 1.9 -0.0 0.4 0.6 1.6 0.5 -1.5 -0.2 -2.0 0.1 0.2 1.9 -0.7 -0.1 -2.2 0.5 -3.4 0.9 -1.9 -2.4 0.7 -1.6 -0.2
Supplements: Zinc 0.9 1.0 3.4 0.1 -1.4 -1.6 -1.0 -0.9 0.0 1.0 0.0 -0.8 -1.3 -0.8 -0.6 -1.6 -0.7 1.8 -0.1 0.7 -0.9 -0.4 1.1 -0.7 -1.4 0.6
Medication: Co-codamol 1.1 1.2 2.8 1.2 -0.0 -0.9 0.7 1.4 0.9 -1.7 1.4 -0.9 -1.4 -0.9 0.5 0.0 -0.4 -1.6 0.1 -1.4 1.1 0.3 -1.3 1.4 -1.6 1.4
Medication: Metformin 0.7 1.0 5.8 0.9 -0.4 -0.6 0.1 0.9 -0.1 -1.5 1.3 -1.1 -1.7 -1.4 -0.0 -0.3 -0.4 -0.5 0.8 -1.3 -0.1 0.7 -0.7 0.7 -2.4 1.3
Diabetes (father) 0.3 0.3 1.1 -0.9 -0.8 0.1 -0.3 0.4 1.0 -0.7 0.2 -0.8 -0.8 -0.3 -0.6 -0.2 -0.9 -0.1 0.2 -0.9 -0.1 0.0 -0.7 -0.4 -0.6 -0.1
Diabetes (mother) 0.5 0.7 3.9 0.4 -1.2 -0.1 -0.8 -0.7 -1.5 0.5 0.8 0.2 -0.7 -0.3 -0.7 -0.5 -0.9 0.6 0.3 0.5 -2.0 -0.6 1.1 -0.8 -1.1 0.3
Severe depression (siblings) 1.4 1.5 3.5 1.1 1.1 -0.7 1.8 1.4 0.5 -0.7 1.4 0.6 -1.3 -1.1 1.1 1.7 1.4 -0.6 1.7 0.1 1.4 1.3 0.1 1.9 -1.0 1.8
Pack years adult smoking proportion 0.4 0.6 3.3 0.7 0.5 -0.4 0.7 1.2 0.3 -0.9 0.1 -0.6 -0.7 -0.6 0.9 0.8 0.2 -0.8 0.6 -0.7 1.8 0.2 -0.8 0.9 -0.8 0.7
Impedance of leg (right) 1.8 9.0 19.8 -3.5 -4.1 -0.8 -3.9 -4.4 -1.8 2.3 -3.1 -0.3 0.3 2.4 -3.8 -3.8 -3.4 4.2 -4.3 1.9 -2.7 0.2 1.7 -4.4 0.9 -2.6
Leg fat-free mass (left) 1.2 6.5 24.5 3.5 4.3 2.0 3.4 3.1 -0.1 0.5 2.1 1.8 0.6 -1.9 2.8 3.6 4.5 -2.3 5.0 0.7 0.5 -0.4 0.8 2.7 1.0 1.3
Trunk fat percentage 0.5 1.9 7.3 1.5 -0.5 -1.2 -0.4 -0.2 -1.5 1.4 1.1 0.4 -1.5 -2.1 -0.9 0.3 0.1 2.0 2.3 2.1 -1.3 0.4 2.7 -0.6 -0.8 1.3
Hand grip strength (right) 1.6 4.2 12.8 1.9 1.8 1.1 1.5 2.9 -2.7 -1.6 -1.5 -3.2 1.4 0.5 2.4 0.0 2.1 -2.5 0.9 -2.8 -0.1 -3.6 -2.8 0.9 -2.4 -1.2
Townsend deprivation index at recruitment 1.1 1.5 6.1 2.5 0.6 -0.8 1.0 1.4 0.7 -1.3 0.8 -0.9 -0.9 -1.5 0.9 0.9 1.4 -0.4 1.9 -0.1 1.7 0.5 -0.1 1.6 -1.6 1.7
Current tobacco smoking 0.8 1.3 4.4 -0.4 -0.5 -1.0 -0.6 -0.6 0.9 0.6 0.6 1.1 -1.6 -1.5 -1.2 -0.3 -0.1 1.8 0.6 2.0 -0.3 2.1 2.0 -0.4 -0.0 1.2
Average weekly fortified wine intake 0.7 0.9 4.4 -1.3 -0.1 0.1 -0.2 -1.2 0.8 1.3 -0.2 2.1 1.3 0.7 -0.6 -1.0 -0.6 -0.6 -0.7 0.0 -1.1 -0.4 0.0 -0.4 1.8 -0.8
Maternal smoking around birth 0.6 0.9 3.0 -0.0 -0.9 0.3 -0.8 -0.7 -1.2 1.7 -0.9 0.4 0.2 0.5 -1.0 -1.2 -0.7 1.3 -0.1 1.1 -1.0 -0.6 1.4 -1.6 0.0 -1.0
Fed-up feelings 0.4 0.7 4.4 2.1 0.9 1.4 0.8 0.7 0.7 -0.4 0.1 -0.2 0.0 -1.1 0.9 0.8 0.9 -0.8 1.3 -0.2 0.9 0.9 -0.3 0.6 -0.2 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.4 1.8 5.3 2.3 1.4 1.0 1.8 1.7 0.2 0.6 2.0 0.4 -0.4 -2.2 0.9 1.1 1.6 -0.7 2.2 0.3 1.1 -0.6 0.7 1.7 -0.9 1.4
Relative age voice broke 1.0 1.6 8.6 -0.7 -1.4 -0.2 -2.9 -1.0 -0.7 -1.3 -1.0 -2.0 0.2 1.2 -0.6 -1.4 -2.0 0.4 -2.0 -0.7 -0.6 1.1 -0.9 -1.4 -0.5 -0.7
Taking other prescription medications 1.4 2.2 8.2 2.7 -0.5 -2.0 0.4 0.9 -0.3 -1.3 1.6 -1.3 -2.1 -1.9 0.8 -0.1 -0.4 -0.7 0.8 -1.4 1.5 -0.1 -0.7 1.9 -2.9 2.3
Age when periods started (menarche) 1.5 3.6 16.5 -1.0 -2.4 -1.9 -2.8 -1.1 -4.1 -0.8 -1.7 -2.7 0.0 1.5 -0.7 -2.3 -2.6 1.0 -2.7 -1.4 -0.9 -1.5 -1.1 -2.1 -1.3 -1.4
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 3.1 0.4 1.3 0.4 1.1 0.5 -0.7 -0.6 0.1 0.4 0.3 0.8 1.5 1.8 1.1 -1.2 -0.3 -0.6 1.8 0.1 -0.9 1.3 1.0 0.4
Heel bone mineral density (BMD) T-score, automated (left) 1.6 3.5 18.8 -1.6 -0.7 1.3 -0.9 0.0 -1.8 0.2 -1.0 -0.7 1.7 3.2 -0.0 -2.2 -1.5 -1.8 -1.5 -2.5 -2.7 -4.3 -1.9 -1.8 0.0 -2.5
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 5.1 0.4 1.8 0.6 0.6 1.4 -1.1 -2.3 0.2 -1.2 1.4 0.9 1.3 2.0 0.4 -1.7 -0.2 -1.3 1.6 0.0 -1.9 1.1 0.4 -0.3
Qualifications: CSEs or equivalent 0.8 1.0 4.0 1.6 1.0 1.6 1.3 1.2 2.0 -0.3 0.2 0.5 0.6 -0.6 0.7 0.0 0.8 -1.9 1.5 -0.7 -0.5 -0.0 -0.8 0.7 0.1 -0.3
Serious illness, injury or assault to yourself 1.0 1.2 4.1 1.5 1.5 1.3 1.8 1.7 1.3 -0.3 0.6 -0.2 0.5 -1.3 1.1 1.1 1.6 -0.8 2.0 0.0 0.4 0.1 0.1 1.2 -0.7 0.4
High blood pressure 0.4 1.0 6.4 2.5 0.1 -0.7 1.1 1.2 0.1 0.4 0.8 -0.8 -0.8 -1.2 1.0 -0.1 0.1 -0.9 1.3 -0.7 0.3 -1.5 0.0 0.6 -1.7 0.6
Hayfever, allergic rhinitis or eczema 4.4 9.5 45.8 -3.5 1.9 3.8 0.2 -1.5 -2.3 1.7 -5.2 2.0 4.5 6.8 -0.1 1.4 1.2 0.0 -3.3 1.3 0.0 -1.1 -0.3 -2.3 5.4 -5.3
Multivitamins +/- minerals 1.7 2.1 9.6 -2.0 0.3 -0.3 -0.4 -1.4 0.5 1.0 0.4 1.9 -0.1 -0.1 -1.7 1.3 -0.0 2.2 -0.5 3.1 0.0 3.1 2.2 -0.4 1.8 0.6
Stomach or abdominal pain in last month 1.0 1.2 3.4 1.8 1.6 1.5 1.3 1.6 -0.8 -1.1 0.0 -0.9 0.6 0.1 1.0 1.2 1.3 -1.8 0.9 -0.7 0.7 0.0 -1.2 1.3 -0.0 0.1
Supplements: Glucosamine 0.3 0.4 1.3 -0.5 0.5 0.8 0.2 -0.1 -0.9 1.0 0.0 0.4 1.0 0.2 -0.7 0.1 0.3 0.6 -0.3 1.2 -0.8 -0.6 0.8 -0.3 0.5 -0.2
Diverticular disease/diverticulitis (self-reported) 1.5 1.8 7.3 1.8 0.9 1.2 0.5 1.9 2.7 -2.2 0.7 -2.1 0.9 -0.5 1.2 0.0 0.2 -2.0 0.3 -1.9 0.9 -0.2 -1.6 1.2 -0.3 0.2
Medication: Atenolol 0.5 0.7 2.1 -0.4 -0.9 -0.9 -0.9 -0.7 -0.7 1.0 0.2 0.4 -0.5 1.2 -0.9 -1.4 -1.0 0.7 -1.1 0.7 -0.6 -1.1 0.9 -0.7 0.3 -0.3
Medication: Levothyroxine sodium 2.9 4.9 18.6 4.3 -1.1 -2.5 0.6 1.1 1.3 -2.4 2.4 -2.2 -3.1 -3.7 0.6 -0.5 -0.6 -1.1 1.3 -1.8 1.9 1.1 -0.9 2.3 -3.8 3.4
Sitting height 0.6 3.9 14.7 -0.1 1.9 1.6 0.8 -1.1 -1.8 3.5 1.0 3.8 1.5 -0.3 -1.1 1.0 1.9 0.7 1.7 3.3 -2.6 -0.5 3.1 -0.4 3.2 -0.3
Chronic bronchitis/emphysema (father) 0.5 0.6 5.2 0.3 -1.0 -1.0 -0.2 -0.4 -2.3 0.6 0.2 0.1 -1.1 0.2 -0.7 -0.2 -1.0 0.9 -0.4 0.5 0.1 -0.7 0.9 -0.3 -0.9 0.7
High blood pressure (mother) 0.7 1.0 3.0 0.1 -0.9 0.4 -1.1 -0.8 -1.0 -0.3 -1.0 -1.2 0.8 1.1 -0.3 -1.3 -0.8 -0.4 -0.7 -1.0 -1.4 -1.7 -0.9 -1.2 -0.3 -1.7
Body mass index (BMI) 1.3 5.7 22.6 4.5 2.3 0.3 2.6 3.7 -0.4 -0.5 2.2 -1.1 -1.3 -3.2 2.5 2.3 2.8 -1.5 4.8 -0.7 1.4 -1.2 0.2 2.6 -2.5 2.3
Impedance of leg (left) 1.2 6.1 13.7 -2.8 -3.7 -1.1 -3.2 -3.5 -1.3 1.4 -2.4 -0.8 0.4 1.6 -3.4 -3.4 -3.1 3.3 -3.5 1.1 -2.4 -0.1 1.0 -3.6 -0.2 -1.9
Leg predicted mass (left) 1.2 6.5 24.9 3.5 4.3 2.1 3.4 3.1 -0.0 0.5 2.1 1.9 0.6 -1.9 2.7 3.6 4.5 -2.2 5.0 0.8 0.4 -0.3 0.9 2.7 1.0 1.2
Trunk fat mass 0.5 2.0 11.9 2.3 1.1 -0.1 0.8 1.1 -1.4 1.3 1.3 0.5 -0.7 -2.1 0.3 1.3 1.7 0.8 3.5 1.6 -0.9 -0.3 2.2 0.3 -0.6 1.2
Waist circumference 1.0 3.5 10.9 3.2 2.9 1.6 2.4 2.6 -1.2 0.2 1.0 0.3 -0.2 -1.3 2.0 3.0 3.1 -1.1 3.3 0.5 1.5 -0.0 0.7 1.8 -0.1 1.1
Number of incorrect matches in round 0.7 1.2 3.7 -1.5 -1.0 -0.8 -1.6 -1.7 0.6 -0.7 -0.6 -0.1 0.2 1.8 -1.0 -0.5 -1.7 0.7 -1.9 0.1 0.0 1.5 -0.1 -0.9 1.4 -0.6
Past tobacco smoking 0.7 1.3 5.7 -1.6 -0.6 1.1 -0.5 -1.2 0.2 -0.3 -0.5 1.0 0.9 1.9 -0.8 -0.9 -1.7 -1.0 -2.4 -0.7 -0.8 -0.2 -1.1 -0.8 1.6 -1.6
Alcohol usually taken with meals 1.5 2.4 10.5 -2.0 1.4 1.6 0.5 -0.5 -0.6 1.4 -2.0 1.7 2.6 2.8 -0.1 0.4 1.0 0.5 -1.7 1.3 -0.7 0.0 0.5 -1.2 3.2 -2.2
Nervous feelings 0.7 1.2 4.1 0.6 1.6 1.8 0.9 0.0 0.8 1.3 -0.3 1.9 1.9 1.4 -0.2 0.6 1.0 -0.1 -0.0 1.0 -0.4 1.0 0.9 -0.0 2.0 -1.1
Frequency of tenseness / restlessness in last 2 weeks 2.9 4.6 15.1 2.3 2.8 0.9 3.9 2.4 2.1 0.8 3.0 1.9 -0.2 -2.6 1.3 1.8 2.8 -1.3 3.7 0.6 1.4 -0.1 0.9 3.0 -0.0 2.5
Hearing difficulty/problems with background noise 0.1 0.1 2.0 1.4 0.5 -0.3 0.2 0.2 0.2 0.1 -0.1 -0.1 0.1 0.5 -0.1 0.0 0.2 0.1 -0.1 0.4 -0.1 -0.2 0.5 -0.0 -0.3 -0.1
Hair/balding pattern: Pattern 2 0.8 1.1 3.9 1.1 1.9 0.7 1.6 1.6 -0.5 -0.3 0.4 -0.2 0.7 0.1 0.7 1.6 1.2 -1.2 0.7 -0.4 2.0 -0.8 -0.7 1.4 0.4 0.5
Had menopause 0.3 0.3 1.8 0.3 0.9 1.1 0.2 0.3 0.1 0.4 -0.6 -0.3 1.4 -0.5 1.1 0.4 0.3 0.3 0.6 0.1 0.4 -0.2 0.3 -0.1 0.4 -0.4
Had other major operations 2.8 3.4 10.2 2.8 2.7 0.1 2.5 2.0 0.4 -1.6 1.7 -0.5 0.2 -1.7 1.7 3.2 2.3 -1.3 2.1 -0.5 2.0 0.9 -0.6 2.9 -0.7 2.0
Forced vital capacity (FVC) 0.2 0.7 3.5 0.9 0.6 -0.7 0.4 -0.2 -0.7 1.0 1.1 1.9 -0.1 -1.3 -0.6 0.0 0.9 -0.1 1.1 0.9 -1.0 0.1 0.9 0.6 1.1 0.9
Heel bone mineral density (BMD) T-score, automated (right) 1.7 3.9 28.6 -0.7 -0.4 1.0 -0.3 0.9 -2.6 -0.6 -0.4 -1.4 1.2 2.5 0.7 -2.1 -1.1 -2.7 -1.0 -3.4 -2.1 -5.3 -2.6 -0.9 -0.9 -1.7
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 2.6 0.0 -0.7 -0.9 -0.0 -1.0 -0.1 0.3 1.2 0.8 -1.4 -1.1 -1.6 0.1 -0.6 0.7 0.4 1.1 0.5 1.0 0.7 0.3 -0.0 1.3
Qualifications: None of the above 0.8 1.6 5.3 1.1 1.2 1.0 0.4 1.9 -0.7 -2.0 0.1 -2.3 1.2 0.2 1.3 1.0 0.2 -1.7 -0.3 -1.9 1.8 -0.5 -2.1 1.0 -0.7 -0.1
Financial difficulties in last 2 years 0.7 1.0 3.6 0.3 -0.6 -0.4 1.8 -0.3 1.6 1.1 0.8 0.9 -1.9 -1.6 -1.1 -0.2 -0.1 0.1 1.4 0.5 0.4 0.5 0.7 0.5 -0.8 1.3
Mouth/teeth dental problems 0.5 0.7 2.2 -1.1 0.4 0.5 0.0 -0.1 1.0 -1.4 -1.0 -0.1 0.2 1.2 0.9 1.0 0.6 -0.5 -0.8 -0.1 0.9 1.2 -0.9 0.2 1.5 -0.6
Heart attack 0.4 0.5 2.5 0.5 0.0 0.9 -0.2 0.1 0.7 0.6 0.7 -0.2 0.1 -0.6 0.0 -1.6 -1.1 -0.5 -0.1 -0.7 -0.7 -1.5 0.1 -0.3 -0.1 -0.1
Allergy 2.6 6.0 28.1 2.1 -2.1 -3.2 -1.1 0.6 2.0 -1.5 4.2 -1.5 -3.9 -5.3 -0.4 -1.7 -1.9 0.0 2.0 -0.9 -0.5 1.7 0.2 1.3 -4.0 4.0
Pain all over the body in last month 0.9 1.0 3.0 -0.8 -1.6 -0.6 -1.3 -0.3 0.2 -1.7 1.0 -0.4 -0.7 0.0 -0.8 -1.5 -1.6 -0.7 -1.0 -1.4 -0.9 0.9 -1.0 -0.2 -1.0 0.2
Diabetes (self-reported) 1.0 1.5 7.9 1.7 -0.1 0.0 0.6 1.6 -2.0 -0.5 1.0 -1.2 -0.5 -1.3 0.5 -0.9 -0.1 -1.1 1.6 -1.9 -1.1 -1.6 -0.8 0.3 -2.8 0.4
Hayfever/allergic rhinitis (self-reported) 1.2 1.6 5.4 -1.1 0.7 1.3 0.7 -0.1 -2.1 0.8 -2.2 1.1 2.2 2.3 -0.5 0.3 0.5 -0.1 -1.4 0.4 0.6 -0.4 -0.1 -1.0 1.8 -2.1
Medication: Ramipril 1.2 1.5 6.4 1.9 1.3 1.0 1.2 1.7 1.1 -0.4 0.7 -0.9 0.7 -0.4 1.8 0.8 0.6 -1.7 1.0 -1.3 1.4 -2.5 -0.9 1.1 -0.2 0.1
Medication: Simvastatin 2.3 3.3 9.8 2.1 0.6 -0.6 0.6 2.8 -0.2 -2.3 2.0 -2.8 -1.0 -1.8 1.5 -0.1 -0.1 -2.4 1.8 -2.8 0.9 -1.3 -2.2 1.8 -3.1 1.7
Fluid intelligence score 0.5 1.0 2.8 -0.7 -1.6 -0.7 -1.4 -1.1 -1.4 0.9 -0.7 -0.6 -0.6 0.5 -0.2 -1.7 -0.7 0.6 -0.4 0.0 -1.6 -1.7 0.3 -1.1 -1.2 -0.3
Illnesses of siblings 1.1 1.5 6.2 -1.9 0.2 0.4 -0.1 -1.5 0.2 0.7 -1.1 2.1 0.7 1.4 -0.9 0.6 0.0 0.7 -1.2 1.6 -0.7 2.5 0.5 -0.5 2.5 -0.7
Neuroticism score 0.4 0.9 4.3 1.2 0.3 0.7 1.1 -0.1 2.1 0.4 1.4 1.3 -0.4 -0.7 -1.0 0.6 0.4 -0.2 0.9 1.0 0.1 1.1 1.0 0.6 0.8 0.8
Weight 1.0 4.9 22.6 3.6 3.5 1.7 2.7 3.0 -1.1 0.8 1.5 0.6 0.4 -2.0 2.4 2.9 3.8 -1.4 4.7 0.6 0.3 -1.1 1.0 2.0 -0.1 1.1
Impedance of arm (right) 4.3 20.0 55.1 -6.3 -4.4 -1.6 -5.5 -7.4 -1.5 3.8 -3.2 3.4 0.1 2.9 -5.9 -2.9 -4.2 6.2 -5.2 5.5 -3.8 4.0 4.2 -5.6 4.7 -2.6
Arm fat percentage (right) 0.5 2.0 7.3 2.1 -0.1 -1.1 -0.0 0.4 -1.5 1.4 1.4 0.4 -1.8 -2.5 -0.5 0.6 0.6 1.5 2.7 1.8 -0.7 0.1 2.6 0.1 -1.0 1.7
Trunk fat-free mass 1.5 8.4 28.2 3.7 5.3 3.4 4.0 4.1 -0.5 0.3 1.1 0.7 2.2 -0.8 3.9 3.4 5.1 -3.4 4.7 -0.7 0.7 -2.1 -0.4 2.8 0.7 0.1
Hip circumference 0.8 3.6 11.8 1.4 1.5 0.4 1.2 0.1 -1.9 2.8 1.6 3.2 -1.0 -2.1 -0.5 1.6 1.8 1.2 3.4 3.3 -0.9 1.0 3.4 0.3 1.5 1.3
Time employed in main current job 0.9 1.0 4.7 1.1 0.3 -0.2 0.6 1.6 0.4 -1.1 1.1 -0.9 -0.7 -0.0 0.8 0.2 1.0 -1.2 1.0 -1.6 -0.1 -1.3 -0.7 1.0 -2.2 0.5
Alcohol intake versus 10 years previously 0.4 0.6 2.5 1.4 -1.4 -0.8 -0.6 -0.2 -0.2 -0.4 0.2 -1.1 -1.3 -0.4 0.1 -0.9 -0.9 0.2 -0.6 -0.5 0.2 0.8 -0.3 0.2 -1.6 0.6
Father’s age at death 1.6 2.1 5.7 -1.9 -1.6 -0.7 -2.4 -1.8 -0.9 1.1 -0.9 -0.2 -0.7 1.0 -1.6 -1.8 -2.4 2.1 -2.0 0.8 -1.2 0.4 0.9 -2.0 0.7 -0.8
Worrier / anxious feelings 0.4 0.8 3.1 -0.4 1.0 1.5 0.9 0.3 1.0 -0.6 -0.1 0.9 0.6 1.2 -0.2 1.0 0.3 -1.4 -0.6 -0.1 1.2 0.9 -0.5 0.5 1.7 -0.8
Frequency of tiredness / lethargy in last 2 weeks 1.4 2.3 6.7 2.6 0.8 0.2 1.5 1.6 1.7 -1.8 1.6 -0.4 -1.1 -1.7 1.6 1.0 1.5 -1.7 1.8 -0.6 1.7 0.5 -0.8 2.4 -1.9 1.9
Falls in the last year 0.7 0.9 4.0 -0.5 0.6 0.1 0.5 -0.1 1.2 -0.2 1.7 1.7 -0.6 -0.7 -0.4 1.7 -0.5 -0.4 0.1 0.5 1.0 2.0 0.2 0.7 1.5 0.9
Hair/balding pattern: Pattern 3 0.2 0.3 0.8 0.7 -0.3 -0.8 -0.8 0.2 0.9 -0.1 0.5 -0.1 -0.3 -0.8 -0.3 -0.3 -0.9 0.7 -0.1 0.3 0.4 0.5 0.3 0.0 -0.7 0.5
Number of live births 0.2 0.2 1.1 1.0 0.2 -0.8 0.2 -0.1 0.5 0.2 0.6 0.4 -0.2 -0.6 -0.0 0.1 0.3 -0.0 0.8 0.4 -0.6 -0.3 0.5 0.1 0.2 0.5
Forced expiratory volume in 1-second (FEV1) 0.4 1.3 5.8 0.9 1.4 -0.1 1.3 0.1 -0.1 0.4 1.2 2.4 0.0 -1.0 0.0 1.3 1.8 -0.8 1.4 0.9 -0.4 1.1 0.4 1.4 1.9 1.1
Pulse rate 1.3 2.2 8.6 1.2 2.0 0.5 2.9 1.8 1.6 -0.8 1.6 1.2 0.5 -0.6 1.3 2.1 1.8 -2.0 1.8 -0.9 1.0 0.3 -0.5 2.2 0.1 1.4
Happiness 0.9 1.1 3.6 -0.1 -1.1 -1.8 -0.3 -0.4 -0.2 0.7 1.1 1.4 -1.5 -1.3 -1.5 -1.3 -1.9 0.4 -0.3 0.6 -0.8 0.1 1.3 -0.2 -0.6 1.3
Noisy workplace 0.4 0.4 2.1 1.0 -0.4 0.1 -0.4 0.6 0.1 -0.5 0.6 -0.6 -0.5 -1.4 -0.8 0.1 0.6 0.5 1.4 0.4 -0.3 0.1 0.3 -0.0 -1.2 0.5
Qualifications: A levels/AS levels or equivalent 0.2 0.4 1.8 -1.3 -1.1 -0.7 -0.8 -1.3 0.3 0.7 -0.5 0.1 -1.0 -0.1 -0.0 -0.9 -0.2 0.4 -0.5 0.4 -0.2 -0.2 0.4 -0.2 0.3 0.3
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 3.1 -0.1 1.0 0.6 1.0 0.7 0.1 -0.0 -0.8 -1.0 1.6 0.7 1.6 0.4 1.1 -0.6 -0.0 -0.8 -0.1 -1.8 -0.9 0.4 0.0 -0.4
Mouth/teeth dental problems: Dentures 1.0 1.6 6.5 1.3 0.0 0.0 0.3 0.2 -2.5 2.5 0.6 0.5 0.1 -1.9 -0.6 -0.8 0.2 1.1 1.7 1.2 -1.9 -1.7 2.0 -0.7 -0.8 0.1
Asthma 0.7 1.4 5.6 1.1 1.0 1.2 1.6 0.6 -2.3 0.7 -1.9 -0.5 1.8 1.4 0.8 0.9 1.6 0.0 0.1 -0.3 0.7 -2.4 -0.1 -0.1 -0.3 -1.2
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 4.1 0.7 -1.4 -0.0 -0.3 -0.2 -0.3 0.6 0.5 -0.2 -1.3 -1.6 -0.9 -1.2 -0.5 0.7 1.2 -0.4 -0.7 -0.1 0.4 -0.3 -2.0 0.4
Medication: Cholesterol lowering 1.7 2.6 11.2 1.2 -0.3 -0.8 -0.0 2.2 -0.4 -1.6 1.1 -2.6 -0.6 -0.4 1.6 -1.3 -0.6 -2.1 0.6 -3.0 -0.3 -2.6 -1.9 0.7 -3.3 0.6
Depression (self-reported) 2.6 3.1 12.3 1.3 0.5 -0.9 1.7 0.7 0.3 0.4 3.5 2.2 -2.4 -2.3 -0.9 1.7 0.8 0.2 2.4 1.7 2.2 1.0 1.9 2.1 0.2 3.1
Medication: Lansoprazole 0.7 0.8 7.8 -0.2 -0.0 -0.3 0.9 -0.9 2.8 0.1 1.1 1.7 -0.4 -0.4 -0.5 0.2 -0.5 -0.4 -0.1 0.3 -0.5 1.0 0.1 0.4 1.1 0.5
Prospective memory result 0.5 0.6 2.6 -1.2 0.1 0.2 -0.2 -1.0 -0.1 0.2 -1.1 0.4 0.8 1.4 0.3 -0.5 -0.2 -0.5 -1.6 -0.3 -0.5 -0.6 -0.7 -0.5 1.1 -1.2
Lung cancer (father) 1.2 1.4 6.2 2.5 0.5 -1.0 0.6 0.5 0.9 -0.7 1.6 -0.3 -1.0 -1.5 1.0 1.3 0.2 -0.6 1.0 -0.4 2.2 1.2 -0.1 1.8 -0.6 2.0
Illnesses of mother 0.7 0.8 5.4 -1.1 0.3 -0.5 0.1 -0.5 1.0 0.3 -0.5 0.7 -0.1 0.0 -0.8 0.9 0.4 1.3 -0.5 1.4 1.3 2.3 0.8 0.2 1.4 0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.5 4.6 1.1 1.1 -0.2 1.4 -0.0 0.5 0.5 1.3 2.2 -0.1 -2.0 -0.4 1.3 1.7 -0.1 1.7 1.3 -0.6 1.6 0.9 1.2 1.4 1.3
Pulse wave Arterial Stiffness index 1.2 1.4 5.0 -0.7 0.1 1.9 -0.4 -0.9 -2.2 1.7 -1.5 0.9 1.3 0.8 -0.6 0.0 0.4 0.9 -0.2 1.4 -1.1 -0.1 1.1 -1.6 1.4 -1.9
Impedance of arm (left) 3.4 15.6 44.2 -5.9 -4.0 -1.7 -4.6 -6.6 -0.3 3.0 -2.2 3.3 -0.1 2.2 -5.3 -2.2 -3.8 5.5 -4.7 5.1 -3.1 4.4 3.7 -4.6 4.4 -1.8
Arm fat mass (right) 0.6 2.5 14.4 2.9 1.4 0.1 1.2 1.7 -1.2 1.1 1.6 0.4 -0.9 -2.4 0.8 1.5 1.9 0.2 3.8 1.1 -0.2 -0.7 1.9 0.9 -1.0 1.5
Trunk predicted mass 1.5 8.6 28.7 3.8 5.4 3.4 4.0 4.2 -0.5 0.4 1.1 0.8 2.3 -0.7 3.9 3.4 5.2 -3.4 4.7 -0.6 0.7 -2.1 -0.4 2.8 0.7 0.1
Standing height 0.5 4.8 19.6 -1.4 2.7 2.8 0.5 -1.0 -1.7 2.7 -1.3 3.3 3.6 2.0 0.2 1.4 2.6 0.2 0.7 2.6 -2.5 0.1 1.7 -1.1 4.4 -2.4
Length of working week for main job 2.0 2.2 7.8 1.5 0.7 -0.1 1.3 2.2 0.4 -2.8 -0.4 -1.5 -0.1 0.2 1.7 0.6 0.6 -2.6 0.5 -2.7 1.4 -0.3 -2.7 1.4 -1.6 -0.0
Exposure to tobacco smoke at home 0.6 0.7 4.9 -0.3 0.5 1.0 0.4 0.9 1.2 -0.9 -0.1 -0.6 -0.8 0.3 0.7 1.5 0.7 -0.1 0.2 -0.1 2.2 0.9 -0.5 0.7 -0.0 0.5
Breastfed as a baby 0.4 0.5 2.8 0.2 0.9 0.1 1.5 0.4 -0.2 -0.4 0.3 0.5 0.3 -0.0 0.7 1.7 1.2 -0.7 0.4 -0.0 0.8 -0.3 -0.6 0.9 0.6 0.0
Tense / ‘highly strung’ 1.8 2.9 9.7 1.8 0.6 -0.2 2.1 0.4 1.9 1.5 3.1 2.4 -1.6 -2.7 -1.2 0.6 1.2 0.1 3.1 1.6 -0.4 0.9 2.2 1.4 -0.3 2.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.5 2.3 7.5 1.4 2.0 0.9 2.3 1.0 -0.7 1.2 1.6 2.7 -0.2 -0.7 -0.2 2.2 2.4 -0.2 2.2 1.9 0.6 1.2 1.7 1.4 1.2 0.9
Hair/balding pattern: Pattern 4 0.7 1.7 6.0 -0.1 -1.8 -2.4 -0.3 -1.2 -2.5 1.0 1.1 1.3 -2.2 -0.9 -1.2 -0.8 -0.2 1.0 0.6 1.1 -1.1 -0.2 1.6 0.0 -0.9 1.7
Birth weight of first child 1.0 1.9 4.1 1.0 0.4 -0.9 2.0 1.4 0.7 -1.5 1.7 -0.5 -1.3 -1.8 0.7 1.1 0.6 -2.0 1.5 -1.6 1.2 -0.6 -1.6 2.0 -1.3 1.7
Peak expiratory flow (PEF) 0.7 1.7 7.6 0.9 1.9 0.8 1.6 -0.2 -2.0 0.5 -0.0 2.5 1.4 0.7 0.3 1.8 2.3 -1.0 0.6 0.9 0.1 0.3 0.0 1.0 2.8 -0.1
Pulse wave reflection index 1.1 1.4 3.6 -1.0 -0.9 0.4 -1.3 -1.7 -1.5 1.4 -1.6 -0.1 0.7 0.5 -0.9 -1.0 -0.6 1.7 -0.9 1.1 -1.7 -0.6 0.9 -1.9 0.8 -1.7
Ever highly irritable/argumentative for 2 days 0.9 1.1 6.4 0.5 -0.3 -0.7 0.4 -0.0 1.1 -0.2 1.9 1.2 -0.9 -2.5 -1.1 0.1 -0.4 0.1 1.2 0.9 -0.1 1.7 0.7 0.7 -0.0 1.8
Loud music exposure frequency 0.5 0.6 1.7 -0.4 -0.8 -0.0 -0.4 -1.1 0.9 1.1 -0.4 1.3 -0.3 -0.1 -0.9 -0.9 -0.5 0.9 0.3 1.2 -0.9 0.1 1.2 -0.8 0.4 -0.2
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 3.8 -1.1 -1.9 -1.6 -0.8 -1.2 0.3 0.8 0.3 1.2 -1.5 0.1 -1.2 -1.4 -0.9 0.9 -0.2 0.9 -0.6 -0.2 1.2 -0.7 0.1 0.6
Mouth/teeth dental problems: Bleeding gums 2.3 3.0 9.2 0.3 -2.7 -3.0 -0.8 -0.4 0.1 -0.9 2.4 -0.8 -2.6 -2.0 -2.0 -2.0 -3.0 0.0 -0.3 -1.2 -0.6 -0.2 -0.1 0.1 -3.0 2.3
Blood clot in the leg (DVT) 2.2 2.9 9.2 1.3 3.0 2.2 2.4 1.6 3.0 0.7 1.6 0.9 0.7 -1.4 1.4 2.0 2.6 -0.8 2.8 0.6 0.3 0.1 0.7 1.8 0.9 0.8
Medication: Paracetamol 0.5 0.9 3.3 1.6 -0.8 -0.6 0.6 0.9 -0.7 -0.3 1.2 -0.5 -0.6 -1.4 0.5 -0.9 -0.5 -0.9 1.2 -1.1 -0.3 -1.1 -0.4 0.6 -1.8 1.1
Headache pain in last month 0.7 1.2 5.0 2.2 0.8 0.0 0.7 1.2 2.0 -0.5 1.3 -0.3 -0.5 -2.0 0.9 0.2 0.9 -0.6 1.9 -0.3 -0.0 -0.1 0.1 1.3 -0.6 1.1
Medication for cholesterol, blood pressure or diabetes 0.8 1.4 5.2 -2.0 0.5 1.1 -0.2 -1.2 -0.5 0.0 -2.0 0.8 1.2 1.2 -0.5 1.1 0.5 1.1 -1.1 1.4 0.5 1.7 0.2 -0.9 2.3 -1.3
Glaucoma (self-reported) 0.4 0.5 2.2 -1.1 0.5 0.2 0.3 -1.1 0.0 0.5 -0.2 1.5 0.0 -0.4 0.0 0.7 0.3 0.4 -0.3 0.9 -0.2 1.2 0.3 0.1 1.5 -0.3
Gout (self-reported) 0.8 1.1 4.6 -0.9 -1.7 -0.8 -2.1 -0.0 0.2 -1.0 0.6 -1.3 -0.9 0.4 -1.2 -1.1 -2.1 0.5 -1.0 -0.8 0.1 -0.4 -0.5 -0.8 -1.4 0.2
Hypothyroidism/myxoedema (self-reported) 1.7 3.2 10.7 2.6 -2.1 -2.5 -0.3 0.2 0.8 -1.7 1.5 -2.2 -3.3 -3.0 -1.1 -1.1 -1.4 0.3 0.6 -1.2 1.2 1.2 -0.3 0.8 -3.3 2.6
Medication: Amlodipine 0.2 0.3 2.3 1.5 -0.0 -0.2 -0.5 0.3 0.5 0.1 0.4 -0.4 -0.7 -0.9 0.6 0.6 -0.1 0.2 0.6 0.2 0.4 0.2 0.4 -0.1 -1.0 0.3
Medication: Ventolin 100micrograms inhaler 1.3 1.6 9.4 -0.7 -0.1 0.8 -0.4 -1.3 -3.1 1.3 -1.8 0.4 1.4 2.7 0.8 -0.1 0.2 0.3 -1.3 0.3 -0.7 -1.8 0.3 -0.9 0.9 -1.4
Birth weight 0.1 0.3 1.2 -0.3 0.5 -0.1 0.0 0.2 0.5 0.5 1.1 0.7 -0.0 -0.9 -0.5 0.5 0.2 0.4 0.6 1.0 -0.1 0.8 0.6 0.4 0.4 0.6
Chronic bronchitis/emphysema (mother) 0.7 0.8 3.2 1.6 1.1 1.0 1.1 1.6 0.8 -0.3 0.9 -0.1 1.0 -1.3 0.2 0.9 0.8 -0.5 1.8 -0.3 0.0 -0.5 0.0 0.7 -0.4 0.3
High blood pressure (siblings) 0.2 0.4 1.2 1.0 -0.5 -0.3 -0.7 0.4 0.1 -0.2 0.6 -1.1 -0.4 -0.8 -0.3 -0.4 -0.7 0.2 0.5 -0.2 0.8 -0.9 0.4 -0.3 -1.0 0.2
Forced vital capacity (FVC), Best measure 0.2 0.8 2.6 0.9 0.3 -0.5 0.5 -0.3 -0.5 1.2 0.9 1.6 0.1 -1.6 -1.1 0.2 0.8 0.5 1.2 1.3 -1.1 0.3 1.3 0.3 0.8 0.8
Body fat percentage 0.5 2.0 8.1 2.2 -0.3 -1.2 0.2 0.8 -1.6 1.0 1.4 -0.4 -1.7 -2.5 -0.3 0.3 0.5 1.4 2.8 1.2 -0.8 -0.6 2.1 0.0 -1.8 1.7
Leg fat percentage (right) 0.7 2.4 9.6 3.0 0.1 -0.6 1.0 1.8 -1.5 0.6 1.1 -1.3 -1.7 -2.5 0.5 0.3 1.1 0.5 3.1 0.0 -0.1 -1.6 1.2 0.6 -2.7 1.6
Arm fat-free mass (right) 2.0 10.4 31.2 4.7 5.1 2.7 4.6 5.1 0.1 -0.6 2.4 0.1 1.4 -1.8 4.0 3.4 5.0 -4.0 5.6 -1.4 1.2 -2.6 -0.9 3.6 -0.6 1.3
Exposure to tobacco smoke outside home 0.5 0.6 3.4 -0.3 -0.6 -0.2 -0.3 0.3 0.8 -1.8 0.4 -0.5 -0.9 0.7 -0.7 0.7 -0.6 -0.5 -1.1 -0.0 1.2 1.7 -0.5 0.2 0.4 0.7
Comparative body size at age 10 0.4 1.1 6.6 1.0 0.6 2.0 0.2 1.1 0.8 1.4 0.2 0.6 0.5 -1.2 0.2 0.0 1.2 0.4 2.6 0.6 -1.0 -0.7 1.5 -0.4 0.2 -0.4
Number of full brothers 1.6 2.0 5.8 2.0 1.5 -0.9 1.3 1.7 0.5 -2.4 1.0 -1.4 -0.0 -0.7 1.9 1.1 0.8 -2.0 0.2 -1.8 1.7 -0.0 -1.9 2.0 -0.7 0.8
Worry too long after embarrassment 0.2 0.3 1.1 -0.4 0.4 -0.2 0.8 0.0 0.8 -0.6 0.1 0.5 0.2 0.6 0.4 0.3 0.1 -1.0 -0.5 -0.3 0.3 0.6 -0.7 0.8 0.5 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 2.8 3.6 11.4 2.6 1.4 -1.3 3.1 1.7 1.3 -0.5 3.4 1.8 -1.7 -2.1 0.7 1.3 2.0 -1.6 2.4 0.0 1.0 0.5 0.4 3.1 -0.7 3.0
Wheeze or whistling in the chest in last year 1.0 1.8 5.7 1.2 2.3 1.6 1.6 1.8 -0.6 -0.5 -1.3 -0.8 1.8 1.0 2.0 2.1 2.4 -0.7 0.7 -0.4 1.7 -0.8 -0.6 0.9 -0.0 -0.8
Number of children fathered 1.6 1.8 6.2 1.2 2.0 1.2 2.4 1.3 -1.0 0.3 -0.5 0.0 1.0 0.3 2.4 1.6 2.5 -1.3 1.3 -0.5 0.4 -1.8 -0.8 1.2 -0.2 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.1 3.7 1.4 0.9 -0.1 1.9 0.5 -0.0 0.9 1.5 1.3 -0.6 -1.7 0.8 0.7 1.3 -0.8 1.8 0.5 -0.1 -0.2 0.6 1.3 -0.0 1.3
Age at first live birth 0.4 0.8 3.3 -0.6 0.0 -1.4 0.9 -0.4 0.1 0.9 1.5 1.8 -1.0 -1.3 -0.3 -0.2 0.3 -0.3 0.8 0.5 -0.7 -0.4 0.5 0.9 0.3 1.3
Pulse wave peak to peak time 0.8 1.0 3.5 0.5 -0.1 -1.9 0.2 0.7 1.8 -1.4 1.2 -0.7 -1.0 -0.5 0.6 -0.3 -0.5 -0.8 0.0 -1.2 0.7 -0.2 -1.0 1.2 -1.2 1.6
Health satisfaction 0.3 0.4 1.9 1.4 0.4 0.5 0.4 0.7 0.9 -1.1 0.1 -0.6 0.4 0.0 0.7 0.0 -0.5 -0.9 -0.0 -0.9 0.6 0.5 -0.7 0.5 -0.4 0.2
Shortness of breath walking on level ground 0.9 1.1 3.9 1.9 -0.8 0.5 0.4 1.1 0.4 -1.1 1.2 -0.8 -0.9 -1.3 0.4 -0.7 -0.3 -1.1 0.8 -1.4 0.9 -1.2 -0.7 0.5 -2.0 0.6
Qualifications: College or University degree 1.1 3.4 9.2 -2.4 -1.9 -1.4 -2.6 -3.0 -1.0 1.7 -1.1 1.2 -0.8 0.9 -2.0 -1.3 -1.7 2.7 -2.3 2.6 -1.6 1.1 2.2 -2.0 1.5 -0.5
Eye problems/disorders: None of the above 0.2 0.2 1.0 0.4 0.2 0.8 -0.6 0.3 1.0 -0.2 -0.7 -0.6 0.6 0.6 0.0 0.2 0.1 0.2 0.3 0.2 -0.1 0.3 0.0 -0.3 0.5 -0.5
Mouth/teeth dental problems: Loose teeth 0.9 1.1 4.2 -2.0 -0.4 0.3 0.3 -0.6 1.0 1.6 0.3 2.1 -0.6 0.1 -1.9 -0.4 -0.6 1.2 0.2 1.4 -0.8 0.2 1.5 -0.9 0.8 -0.0
Emphysema/chronic bronchitis 1.0 1.1 4.2 1.2 0.9 0.5 2.0 1.0 -0.8 0.3 1.1 1.7 -0.3 -1.0 0.4 1.0 1.8 -0.7 1.8 0.4 0.1 0.4 0.5 1.3 -0.2 1.1
Medication for pain relief, constipation, heartburn 0.7 1.3 3.6 -1.9 1.0 1.7 -0.5 -0.3 0.1 -0.4 -1.8 -0.3 1.5 1.7 0.7 1.2 0.6 0.2 -1.3 0.4 1.0 1.1 -0.5 -0.4 1.8 -1.5
Neck or shoulder pain in last month 0.9 1.2 5.3 1.4 0.5 0.2 1.6 1.3 -0.5 1.0 0.9 0.0 -1.2 -2.3 0.6 -0.5 0.9 -0.2 2.2 -0.2 -0.5 -0.2 0.5 0.9 -1.7 1.4
Medication: Blood pressure 0.7 1.2 4.9 2.2 0.8 -0.3 1.5 1.3 1.4 0.7 2.1 1.1 -0.4 -1.0 0.4 0.1 0.4 -1.3 1.7 -0.4 -0.2 -1.3 0.3 1.1 -0.5 1.0
Angina (self-reported) 1.1 1.5 3.9 1.6 1.2 1.0 0.5 1.0 -1.3 -0.9 -1.4 -2.0 1.4 1.3 1.7 0.2 0.8 -1.4 -0.6 -1.7 0.5 -1.7 -1.6 0.4 -0.6 -1.1
Migraine (self-reported) 0.6 0.7 3.6 1.1 -0.1 -0.9 0.5 0.2 1.3 -0.0 1.1 -0.5 -1.9 -1.3 0.4 -0.3 0.3 0.2 1.3 -0.2 0.7 -0.5 0.2 0.7 -0.9 1.4
Medication: Ibuprofen 0.6 0.7 2.9 0.7 -1.1 0.0 -0.2 -0.2 -0.1 0.4 0.5 -0.1 -1.4 -1.7 -0.8 -1.1 -0.4 0.8 1.1 -0.3 -0.8 0.7 0.5 -0.3 -1.6 0.5
Medication: Allopurinol 1.1 1.5 6.4 -1.7 -2.0 -0.4 -2.5 -1.2 -0.8 -0.3 -0.1 -0.4 -0.4 1.6 -1.3 -1.4 -2.3 0.4 -2.0 -0.3 -0.6 0.1 -0.1 -1.3 0.1 -0.6
Medication: Omeprazole 0.8 1.0 3.6 1.0 1.5 0.5 1.9 0.3 0.3 0.2 0.4 1.2 -0.7 -0.1 0.8 1.6 1.7 -1.0 0.5 0.5 1.0 1.1 0.0 1.5 0.8 0.6
Medication: Seretide 50 evohaler 0.6 0.7 2.5 1.4 0.2 -0.8 1.2 1.1 -1.1 -0.2 0.9 -0.3 -0.7 -0.2 0.4 0.5 0.4 -0.5 0.6 -0.5 1.0 -1.4 -0.1 0.7 -1.6 0.9
Mean time to correctly identify matches 0.1 0.2 0.6 0.3 0.3 -0.7 0.4 -0.1 -0.8 0.4 0.0 0.5 0.0 -0.5 0.2 0.5 0.3 -0.1 0.5 0.5 0.4 0.3 0.3 0.1 0.6 0.3
Heart disease (mother) 0.8 1.0 5.1 -0.0 -1.0 -1.3 -0.3 0.4 -1.3 0.8 0.3 -0.5 -1.3 -0.7 -0.2 -1.1 -0.4 0.7 1.2 -0.1 -1.0 -2.2 0.6 -0.7 -2.2 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.5 1.1 -0.6 -0.8 -0.4 -0.4 -0.5 -0.7 -0.7 -1.2 0.1 0.1 0.7 -1.2 -0.4 -0.2 -0.3 -1.0 -0.6 -1.1 -0.8 -0.0 -0.9 -0.4
Whole body fat mass 0.6 2.6 15.4 3.0 1.4 0.1 1.4 2.0 -1.2 0.8 1.7 -0.0 -0.9 -2.5 1.0 1.4 1.9 -0.0 3.9 0.7 -0.4 -1.1 1.6 1.0 -1.3 1.6
Leg fat mass (right) 1.1 4.1 19.7 3.8 1.9 0.2 2.3 2.9 -1.3 0.5 1.9 -0.5 -1.0 -2.8 1.6 1.8 2.6 -0.7 4.4 -0.0 0.4 -1.7 1.0 1.8 -2.1 1.9
Arm predicted mass (right) 1.8 9.3 29.4 4.5 4.7 2.6 4.3 4.8 0.0 -0.4 2.1 0.0 1.4 -2.0 3.8 3.1 4.8 -3.7 5.4 -1.4 0.9 -2.6 -0.7 3.3 -0.7 1.1
Pulse rate, automated reading 0.1 0.3 1.9 -0.7 0.7 0.5 0.9 1.0 0.3 -0.5 0.3 0.2 0.7 0.1 -0.4 1.4 0.3 -0.5 0.2 -0.2 -0.0 0.3 -0.0 0.2 0.0 -0.0
Alcohol intake frequency. 0.3 0.8 5.5 2.3 1.2 1.6 1.0 1.2 -0.0 -0.4 0.6 -0.4 1.2 0.5 0.2 0.5 0.3 -1.2 0.0 -0.4 0.8 -0.8 -0.5 0.8 0.1 -0.1
Comparative height size at age 10 0.8 4.1 19.0 -0.9 3.2 2.7 1.4 -0.0 -0.2 2.0 -0.2 3.2 2.7 1.0 0.4 2.6 3.2 -0.2 1.8 2.5 -1.1 0.3 1.6 -0.2 4.4 -1.4
Number of full sisters 0.8 1.0 6.0 1.8 0.3 -1.1 -0.1 1.0 -0.3 -0.8 1.5 -0.3 -0.5 -2.4 -0.2 0.7 -0.2 -0.4 1.1 -0.1 0.6 0.7 -0.0 1.1 -1.2 1.5
Suffer from ‘nerves’ 1.0 1.6 5.6 1.7 0.5 0.3 1.6 0.0 1.9 1.1 2.2 2.4 -0.7 -1.3 -0.9 0.4 1.0 -0.0 2.0 1.1 -0.6 0.8 1.7 0.9 0.3 1.2
Overall health rating 1.6 3.4 10.7 3.3 2.2 -0.0 2.1 2.7 0.3 -1.8 1.1 -1.5 -0.9 -1.6 1.8 2.7 2.9 -0.9 2.5 0.1 2.0 1.0 0.0 2.3 -1.7 1.8
Chest pain or discomfort 2.2 3.1 10.6 3.2 1.9 0.2 2.3 2.0 1.3 -1.3 1.2 -0.8 -0.6 -2.4 1.9 2.2 2.3 -1.0 2.7 -0.5 1.8 0.6 -0.2 2.4 -1.5 1.6
Had major operations 0.9 1.0 2.9 0.1 0.7 -1.0 0.3 1.6 -0.2 -1.7 1.5 -0.7 -0.9 -0.0 0.4 0.8 -0.7 -1.2 -0.8 -1.1 1.7 0.4 -1.2 1.3 -0.9 1.1
Age at last live birth 1.0 1.4 8.0 -1.8 -0.3 -0.7 0.6 -1.4 0.7 2.1 0.5 2.8 -0.7 -0.6 -1.5 -0.8 0.1 0.5 0.5 1.5 -1.4 0.1 1.4 -0.4 1.8 0.5
Family relationship satisfaction 0.4 0.5 2.0 -0.8 -0.9 -1.4 0.3 -0.4 0.2 0.4 0.6 0.7 -1.2 -0.8 -0.5 -1.0 -0.9 -0.0 0.0 -0.4 -0.5 -0.7 0.3 0.1 -0.8 0.6
Leg pain on walking 0.3 0.3 2.2 1.5 0.2 0.8 -0.0 -0.6 -0.2 0.4 0.2 0.7 -0.0 -0.3 -0.5 0.2 -0.3 -0.0 -0.0 0.9 0.1 1.0 0.9 -0.2 0.9 -0.2
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 5.2 -0.8 -1.5 -0.2 -1.9 -1.0 0.6 0.9 -1.4 -1.2 -0.9 -1.1 -0.3 -1.2 -1.1 2.3 -0.0 0.7 -0.9 0.8 1.0 -1.7 -1.3 -0.4
Commuting to job workplace: Car/motor vehicle 2.0 2.3 5.6 1.8 2.3 0.9 2.3 2.4 -0.6 -1.2 1.3 -0.0 0.7 0.5 1.8 1.8 1.9 -2.3 1.5 -1.1 1.3 -0.4 -1.2 2.2 -0.3 0.9
Illness, injury, bereavement, stress in last 2 years 0.4 0.4 1.8 0.8 -0.1 -1.2 -1.2 0.3 -1.3 -0.8 0.5 -1.1 -0.4 -1.3 -0.0 0.0 -0.1 0.1 0.5 -0.1 -0.5 -0.2 0.1 0.0 -0.4 0.3
Medication: Aspirin 0.7 0.9 4.4 2.0 -0.3 -1.3 0.2 0.4 0.6 0.1 0.6 -0.6 -0.4 -0.3 0.6 -1.4 0.2 -0.6 1.1 -1.0 -1.5 -2.1 -0.2 0.3 -1.3 0.7
Supplements: Vitamin C 2.2 2.6 8.4 -2.4 -1.3 -0.6 -1.9 -2.2 -1.1 1.5 -1.2 0.5 -0.2 0.0 -2.2 -0.8 -1.3 2.9 -1.0 2.5 -1.4 1.7 1.8 -2.1 1.2 -0.7
Knee pain experienced in last month 0.7 1.1 4.5 -0.5 -1.3 -1.3 -1.4 -0.3 -0.5 0.5 -0.4 -0.7 -1.1 -0.7 -1.5 -0.9 -1.2 2.1 -0.5 1.0 -0.7 0.4 1.3 -1.1 -1.9 0.3
Hypertension (Self-reported) 0.4 1.1 7.1 2.7 -0.2 -0.9 0.7 1.1 0.2 0.3 0.9 -1.0 -1.1 -1.2 1.0 -0.4 -0.3 -0.9 1.2 -0.9 0.2 -1.8 -0.0 0.5 -1.9 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 3.0 0.3 0.9 -0.1 1.4 -0.2 0.6 0.7 0.7 1.7 -0.0 -0.1 -0.3 1.3 0.9 -0.0 0.5 1.0 0.4 1.1 0.7 0.8 0.6 0.6
Illnesses of father: Heart disease 0.9 1.3 4.9 -0.8 -2.0 -1.3 -1.1 -1.7 -1.4 1.0 -0.5 0.5 -0.8 -0.0 -0.9 -2.2 -1.3 0.6 -1.0 0.2 -1.9 -0.3 0.4 -1.1 -0.6 -0.2
Illnesses of siblings: Diabetes 1.1 1.4 6.4 0.4 -0.0 0.0 0.1 1.6 -0.6 -1.1 0.5 -1.6 0.2 0.5 1.4 -0.6 -0.3 -1.4 0.2 -2.3 -1.1 -2.5 -1.4 0.1 -2.2 -0.3
Smoking status: Previous 0.3 0.4 1.5 1.0 0.2 -0.6 -0.0 0.8 -0.4 0.4 -0.2 -1.1 -0.2 -0.4 0.4 0.4 0.8 0.8 1.2 0.2 0.3 -0.2 0.5 0.0 -1.1 0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 2.9 0.4 -0.2 0.5 0.7 -0.9 -1.0 1.6 0.4 1.7 -0.3 -0.7 -0.8 -0.5 0.4 0.2 0.8 0.9 -1.7 0.6 1.3 -0.2 0.3 -0.2
Whole body fat-free mass 1.5 8.4 26.8 4.0 5.1 2.8 4.0 4.1 -0.2 0.3 1.8 1.1 1.6 -1.5 3.6 3.5 5.1 -3.1 5.2 -0.2 0.6 -1.7 0.1 3.0 0.5 0.8
Leg fat-free mass (right) 1.4 7.5 27.7 3.7 4.6 2.0 3.7 3.5 0.4 0.1 2.5 1.8 0.7 -2.2 2.9 3.8 4.7 -2.7 5.3 0.5 0.6 -0.4 0.6 3.1 0.7 1.6
Arm fat percentage (left) 0.5 2.0 8.7 2.1 0.2 -0.9 0.3 0.8 -0.8 1.0 1.7 0.4 -1.8 -2.7 -0.2 1.0 0.8 1.1 3.0 1.6 -0.3 0.3 2.2 0.5 -1.0 1.9
Average weekly red wine intake 1.4 2.0 6.8 -0.5 0.7 -0.4 1.1 -0.4 1.1 2.6 0.9 2.5 -0.3 -1.6 -0.1 0.2 2.0 1.5 2.2 2.6 -1.1 -0.3 2.6 0.2 0.5 0.8
Handedness (chirality/laterality): Left-handed 0.6 0.7 5.8 -0.7 0.7 0.3 -0.4 1.1 -0.2 -1.0 0.4 -1.0 -0.8 -0.5 0.4 1.0 0.1 -0.1 -0.2 0.0 2.4 1.8 -0.2 0.8 -0.0 0.6
Mood swings 1.4 2.6 10.4 1.9 0.4 -0.3 1.8 0.5 1.5 1.1 3.2 1.8 -1.8 -2.9 -1.0 0.9 0.7 0.0 2.7 1.4 0.1 0.9 1.9 1.3 -0.5 2.4
Loneliness, isolation 0.5 0.7 2.4 1.3 0.3 0.6 1.0 0.2 0.8 0.6 1.1 1.1 -0.5 -1.1 -1.4 -0.0 0.4 0.3 1.0 1.2 0.1 0.8 1.5 0.1 0.3 0.9
Long-standing illness, disability or infirmity 1.2 1.8 4.5 2.1 0.6 -1.0 2.0 1.3 0.2 -1.4 1.1 -0.9 -1.1 -1.3 1.6 1.1 0.6 -1.7 0.9 -1.7 1.1 -0.4 -1.2 2.0 -1.9 1.6
Ever had bowel cancer screening 0.6 0.7 3.5 0.6 -0.4 -0.5 0.1 0.7 1.6 -0.1 1.2 -0.2 -0.8 -1.9 -0.8 -0.5 -0.8 0.3 1.0 -0.4 0.3 0.4 0.5 0.2 -1.4 0.9
Diabetes diagnosed by doctor 1.4 2.3 10.3 2.0 0.2 -0.3 0.9 2.2 -2.2 -1.4 1.4 -1.9 -0.7 -1.3 0.7 -0.3 0.2 -1.6 1.6 -2.4 -0.0 -1.8 -1.4 1.0 -3.2 1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.7 3.3 1.3 0.6 0.0 1.0 0.4 0.5 0.7 1.3 1.1 -0.8 -1.2 0.0 0.7 0.6 -0.6 1.8 0.6 0.3 0.0 0.8 0.8 0.5 1.0
Friendships satisfaction 1.0 1.3 5.6 1.1 -1.4 -1.1 0.5 -0.1 1.2 -0.1 1.7 0.4 -1.7 -2.4 -0.3 -1.2 -1.4 -0.5 0.7 -1.0 -0.6 -0.9 0.1 0.4 -1.8 1.4
Qualifications: nursing, teaching 0.3 0.4 3.0 0.5 -0.1 -0.7 0.6 -0.6 0.2 -0.1 0.6 0.3 -1.7 -0.5 0.1 0.6 0.5 -0.3 0.5 0.2 -0.0 0.4 0.2 0.8 0.4 1.2
Commuting to job workplace: Walk 0.4 0.5 2.1 -0.5 -0.4 0.0 -0.9 -1.1 1.0 -0.3 -0.8 -0.1 0.0 0.1 -0.1 0.1 -0.6 0.9 -1.4 0.6 0.5 1.4 0.2 -0.3 0.5 -0.3
Eye problems/disorders: Cataract 0.3 0.3 1.1 0.4 0.3 -0.7 0.8 0.4 -0.2 -0.3 1.0 0.0 -0.5 0.4 -0.3 0.2 0.1 -0.7 -0.4 -0.3 0.5 -0.4 -0.2 0.7 -0.9 0.8
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 2.4 1.2 1.0 -0.1 0.6 0.9 -0.2 0.1 1.5 0.2 0.6 -0.1 0.8 0.0 0.4 -1.2 1.0 -0.8 0.3 -1.0 -0.4 1.3 -0.3 0.8
Medication for cholesterol 0.4 0.6 1.6 -0.9 -0.7 -1.2 -0.9 -0.8 -0.8 0.2 0.4 0.6 -0.0 0.3 -1.3 -0.9 -0.8 0.6 -1.0 0.8 -1.2 -0.1 0.7 -0.7 1.0 0.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.4 1.6 6.5 -1.7 -1.0 -1.0 -1.3 -2.0 0.8 0.4 -0.2 2.0 0.1 1.3 -1.2 -0.3 -1.2 0.9 -2.0 1.3 -0.2 1.9 0.7 -0.7 2.5 -0.3
Back pain experienced in last month 0.3 0.4 2.3 0.5 0.2 -0.0 0.2 0.2 -0.1 0.3 0.3 0.6 -0.2 0.3 -1.5 0.5 -0.7 0.3 -0.6 1.1 0.8 0.8 0.9 -0.2 1.0 0.4
Mineral and other dietary supplements 0.6 0.8 4.1 1.1 -0.5 -0.5 -0.1 0.3 0.3 -1.5 -0.5 -1.1 -0.3 -0.4 1.5 -0.1 -0.4 -1.5 0.0 -2.0 0.9 -0.4 -1.8 0.3 -0.5 -0.0
Breast cancer (self-reported) 0.9 1.1 4.3 0.3 -0.5 -1.7 -0.6 0.8 0.5 -0.9 1.9 -0.5 -2.1 -1.0 -1.0 -0.8 -0.0 0.5 0.4 0.2 0.4 0.3 0.5 0.7 -1.9 2.0
Asthma (self-reported) 0.6 1.2 5.9 1.1 0.5 0.8 1.3 0.3 -2.4 1.0 -1.8 -0.5 1.5 1.2 0.4 0.5 1.3 0.5 -0.1 0.1 0.5 -2.3 0.2 -0.4 -0.5 -1.0
Osteoporosis (self-reported) 0.3 0.4 1.9 0.1 0.5 -0.3 0.7 0.1 -0.1 0.1 -0.4 0.9 0.4 1.4 -0.5 0.6 -0.1 0.1 -1.3 0.7 0.9 0.8 0.3 0.2 0.8 0.0
Osteoarthritis (self-reported) 0.4 0.5 2.3 0.3 -0.1 -1.5 0.7 0.0 0.1 -0.2 1.1 0.8 -0.7 -1.1 0.3 0.6 0.3 0.2 0.3 0.4 -0.1 0.3 0.7 0.8 -0.6 1.4
Medication: Aspirin 0.9 1.2 5.7 2.0 -0.0 -1.2 0.4 0.9 0.5 -0.2 0.6 -0.7 -0.2 -0.2 1.1 -1.5 0.2 -1.3 1.0 -1.7 -1.1 -2.4 -0.8 0.6 -1.5 0.7
Medication: Gliclazide 1.6 1.8 7.4 1.0 -2.0 -2.7 -0.6 0.1 0.4 -0.9 2.0 -0.1 -2.6 -2.1 -1.2 -1.0 -1.3 0.1 0.7 -0.4 -0.5 -0.2 0.1 0.3 -2.3 1.8
Illnesses of father: None of the above (group 1) 0.8 1.0 3.5 0.8 1.5 0.7 0.7 0.1 1.5 -0.9 0.1 -0.0 1.0 0.9 0.9 1.9 1.1 -0.8 -0.2 0.1 1.4 1.3 -0.5 1.0 1.6 0.1
Smoking status: Current 1.0 1.6 5.7 -0.1 -0.0 -1.0 -0.1 -0.4 1.4 0.5 1.1 1.6 -1.8 -2.0 -0.8 0.3 0.4 1.4 1.1 2.2 0.2 2.4 2.1 0.3 0.3 1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 3.5 0.1 -1.1 -1.6 -0.1 -0.6 1.0 -0.9 1.6 0.3 -1.4 -1.6 -0.7 -0.6 -0.9 -0.5 -0.3 -0.4 -0.2 1.1 -0.4 0.9 -0.1 1.9
Whole body water mass 1.5 8.4 26.3 4.0 5.1 2.9 4.0 4.1 -0.2 0.3 1.8 1.1 1.6 -1.4 3.6 3.6 5.0 -3.2 5.1 -0.3 0.7 -1.6 -0.0 3.0 0.6 0.7
Leg predicted mass (right) 1.4 7.4 26.7 3.6 4.6 2.0 3.7 3.4 0.3 0.1 2.4 1.9 0.8 -2.1 2.9 3.9 4.7 -2.7 5.2 0.5 0.6 -0.3 0.6 3.1 0.8 1.5
Arm fat mass (left) 0.7 3.0 16.4 3.2 1.6 0.1 1.5 2.0 -1.0 0.9 1.9 0.5 -1.1 -2.6 1.0 1.8 2.0 -0.2 4.0 1.0 0.1 -0.6 1.7 1.3 -1.0 1.8
Number of self-reported non-cancer illnesses 0.9 1.6 8.1 2.8 0.1 -1.5 1.3 1.0 -0.2 -0.5 1.1 -1.0 -1.4 -1.8 0.7 0.5 -0.1 -0.6 1.0 -0.6 1.6 -0.6 -0.1 1.6 -2.0 1.8
Average weekly champagne plus white wine intake 0.7 1.0 6.5 0.5 1.2 1.0 1.3 -0.5 -0.3 1.5 0.3 2.6 0.9 1.2 -0.0 0.4 1.3 -0.2 0.6 0.8 -0.3 -0.1 0.8 0.5 2.0 -0.0
Miserableness 0.2 0.4 3.0 0.6 0.2 1.7 0.5 0.4 0.9 -0.2 0.9 0.7 -0.3 -0.5 -0.9 -0.1 0.1 -0.8 0.9 -0.2 -0.0 0.3 -0.2 0.3 0.0 0.3
Guilty feelings 0.7 1.0 4.3 -0.0 0.2 -0.4 0.5 0.9 2.1 -1.4 1.2 -0.5 -1.6 -1.3 -0.7 1.1 -0.4 -0.3 0.4 0.1 1.2 1.9 -0.1 0.9 -0.7 1.5
Wears glasses or contact lenses 1.7 1.9 5.6 -1.6 0.4 1.6 -0.7 -1.1 -1.6 1.2 -1.8 1.8 2.4 2.1 0.3 -0.4 -0.8 -0.0 -1.4 0.4 -0.7 0.8 -0.0 -1.3 2.3 -2.4
Ever taken oral contraceptive pill 2.1 2.4 7.6 2.7 1.7 -0.0 1.7 1.5 0.2 0.3 1.6 0.3 -0.6 -1.8 1.0 1.7 2.1 0.1 2.6 1.2 1.5 1.1 1.4 2.1 -1.0 2.2
Hearing aid user 0.7 0.7 3.5 -0.2 0.2 0.6 -0.4 -0.4 1.5 0.7 -1.9 -0.7 1.4 1.0 -0.2 -0.6 0.3 0.6 -0.3 0.1 -1.1 -0.9 -0.1 -1.1 0.7 -1.4
Mother’s age at death 1.2 1.5 6.7 -0.7 -0.1 0.4 -1.0 -1.5 -2.6 0.8 -1.6 0.0 1.6 2.5 0.4 -1.0 -0.8 -0.2 -2.0 -0.2 -0.7 -0.8 -0.3 -0.8 1.5 -1.3
Financial situation satisfaction 0.6 0.8 2.4 0.7 0.0 -1.0 0.7 1.2 1.5 -0.8 1.2 -0.0 -0.9 -1.2 0.4 -0.1 -0.9 -1.2 0.4 -1.1 0.5 -0.1 -0.8 0.8 -1.1 0.9
Tinnitus: Yes, now most or all of the time 0.6 0.7 3.7 0.1 0.9 1.1 0.1 -0.6 -0.7 0.7 -1.9 0.6 1.4 0.8 0.4 0.3 0.7 0.3 -0.4 0.4 -0.6 0.6 0.2 -0.6 1.1 -1.5
Commuting to job workplace: Public transport 1.3 1.6 5.6 -0.8 -2.1 -1.5 -2.4 -1.4 -0.0 0.2 -1.6 -1.5 -0.3 -0.3 -0.8 -1.8 -1.6 1.6 -1.5 -0.2 -0.4 -0.6 0.2 -1.6 -1.0 -0.7
Eye problems/disorders: Glaucoma 0.4 0.4 3.0 -0.4 0.6 -0.3 0.2 -0.7 -1.7 1.0 0.3 0.9 -0.3 -0.6 0.3 0.5 0.7 0.6 0.3 0.9 -0.6 0.3 0.5 0.2 0.6 0.1
Medication: Blood pressure 0.5 1.0 5.0 2.0 -0.5 0.0 0.1 0.6 -0.1 0.2 -0.4 -1.9 -0.5 -0.9 1.2 -1.1 -0.0 -0.3 1.0 -1.2 0.2 -1.9 -0.4 -0.0 -2.2 -0.2
Pain type(s) experienced in last month: Hip pain 0.3 0.4 1.7 -0.7 -0.8 -0.5 -0.4 -0.1 0.8 0.4 0.4 -0.1 -0.6 0.1 -1.3 -1.1 -1.0 0.7 -0.5 0.1 -0.7 0.1 0.7 -0.7 -0.4 0.0
Supplements: Fish oil (including cod liver oil) 0.7 1.0 4.0 -1.6 -0.9 0.2 -0.9 -1.3 -1.1 0.8 -0.0 0.3 0.1 0.9 -1.8 -1.3 -1.0 0.6 -1.0 0.6 -2.0 -0.4 0.7 -1.1 0.2 -0.7
High cholesterol (Self-reported) 1.9 3.4 15.6 2.8 -1.1 -1.1 -0.1 1.6 -1.4 -1.5 0.9 -3.1 -1.2 -1.3 1.4 -1.4 -0.7 -1.8 1.4 -3.0 0.2 -2.9 -1.9 0.6 -3.9 0.8
Medication: Bendroflumethiazide 0.6 0.9 4.2 2.1 0.4 -0.2 1.1 0.9 -0.1 -0.5 0.9 -0.3 -0.7 -1.2 0.9 0.7 0.6 -1.0 1.0 -0.7 1.5 -0.4 -0.6 1.2 -0.9 0.9
Medication: Paracetamol 0.6 0.9 3.0 0.6 -1.4 -1.2 -0.1 0.3 -0.9 -0.2 1.5 -0.2 -1.1 -0.8 -0.3 -1.7 -1.4 -0.6 0.1 -1.1 -0.6 -0.8 -0.2 0.2 -1.7 1.2
Medication: Lisinopril 0.2 0.3 1.4 0.5 -0.1 0.3 0.3 0.1 0.1 -0.2 0.2 -0.4 0.0 0.6 0.1 -0.7 -0.6 -1.2 0.0 -1.2 -0.3 -1.0 -0.9 0.1 -0.5 -0.3
Medication: Atorvastatin 1.3 1.6 6.1 2.5 0.0 -0.6 1.2 1.6 0.3 -1.3 0.4 -1.3 -1.6 -1.5 1.3 0.5 0.7 -1.3 0.9 -1.5 1.4 0.1 -1.1 1.4 -2.0 1.1
Illnesses of father: High blood pressure 0.5 0.7 2.2 0.2 0.2 0.9 0.4 0.6 0.6 1.4 0.6 1.4 -0.7 -1.4 -0.9 -0.3 0.1 0.4 1.2 1.2 -0.7 -0.2 1.5 -0.4 0.0 0.1
Alcohol drinker status: Never 0.6 0.7 2.9 0.3 1.3 1.7 0.7 1.0 -0.1 -0.3 0.5 0.7 1.5 1.1 0.1 1.3 0.8 -1.1 -0.3 0.0 0.4 -0.4 -0.6 0.3 1.1 -0.6
Ever smoked 0.8 1.4 4.3 1.3 -0.0 -2.0 -0.2 0.9 0.1 -0.8 0.7 -1.5 -1.7 -2.0 0.5 0.6 0.7 0.9 1.6 0.3 1.1 0.9 0.6 1.0 -1.9 2.1
Basal metabolic rate 1.4 7.8 27.2 4.1 4.8 2.5 3.8 3.9 -0.4 0.4 1.8 1.1 1.1 -1.8 3.4 3.5 4.9 -2.8 5.2 0.0 0.7 -1.4 0.3 2.9 0.4 1.0
Leg fat percentage (left) 0.9 3.1 13.0 3.4 0.5 -0.5 1.5 2.4 -1.2 0.3 1.5 -1.4 -1.5 -2.9 0.8 0.6 1.4 0.1 3.6 -0.3 -0.0 -1.8 1.0 1.0 -3.2 1.9
Arm fat-free mass (left) 1.7 8.4 27.6 4.7 4.6 2.9 3.8 4.3 -0.8 0.4 1.5 0.2 1.5 -1.4 3.7 2.8 4.8 -3.2 5.3 -0.9 0.6 -2.9 -0.2 2.6 -0.4 0.5
Number of operations (self-reported) 2.6 3.8 18.8 1.4 3.3 1.1 2.7 2.5 1.2 -1.5 1.5 -0.0 0.5 -0.3 2.1 4.3 2.8 -1.5 1.8 -0.2 2.6 1.0 -1.0 2.6 0.1 1.3
Average weekly beer plus cider intake 0.3 0.4 1.8 0.3 -0.7 -0.8 -0.7 -0.2 0.8 -0.6 -0.2 -0.8 -0.9 -1.3 -0.5 -0.3 -0.2 0.3 0.1 -0.0 -0.1 1.1 -0.1 0.1 -0.8 0.6
Irritability 0.6 1.0 4.1 2.0 -0.2 -0.9 1.3 -0.5 1.3 0.6 1.2 0.5 -1.0 -1.7 0.6 -0.0 0.9 -0.4 1.2 0.1 0.4 -0.8 0.5 1.1 -0.5 1.5
Risk taking 2.8 4.0 15.9 1.1 -0.0 -2.2 2.7 0.9 1.4 1.4 3.0 1.5 -3.3 -4.0 -0.5 1.1 0.6 0.7 3.0 1.2 1.2 0.3 1.7 1.9 -2.1 3.3
Ever had prostate specific antigen (PSA) test 2.2 2.6 6.7 -1.7 -1.0 0.9 -2.1 -1.9 0.3 0.6 -1.9 0.6 1.6 2.4 -1.4 -1.8 -2.1 1.0 -2.1 0.3 -1.3 1.1 0.2 -2.6 1.9 -2.5
Fractured/broken bones in last 5 years 1.0 1.2 3.9 0.2 1.1 1.0 -0.1 -1.1 -1.3 0.1 -1.6 0.1 1.6 0.2 0.6 1.8 1.1 1.1 -0.7 1.5 0.9 2.0 0.6 -0.3 1.9 -0.9
Age started oral contraceptive pill 0.6 0.7 3.3 1.8 1.6 0.6 1.1 1.4 -1.6 0.5 0.4 -0.2 0.7 -0.3 0.7 0.6 0.9 -0.4 0.8 0.0 0.0 -0.2 0.5 0.8 -0.5 0.4
Diastolic blood pressure, automated reading 0.3 0.9 4.9 -0.2 -1.3 -1.1 -0.1 0.5 0.6 -0.8 1.6 0.3 -2.2 -0.7 -1.0 -1.0 -1.7 -0.9 -0.4 -0.9 -0.7 -0.2 -0.1 0.1 -1.3 0.8
Ever depressed for a whole week 1.8 2.3 10.4 -0.6 -0.8 -0.4 0.6 -1.7 -0.8 2.5 0.9 3.2 -0.8 -1.0 -2.1 -1.0 -0.5 1.5 0.9 2.5 -1.8 0.9 2.6 -0.6 1.0 0.6
Unable to work because of sickness or disability 1.3 1.7 7.4 1.1 1.4 0.4 1.0 1.5 0.4 -1.6 1.5 -0.4 -0.4 -1.1 0.3 2.2 0.8 -1.5 0.5 -0.2 2.7 2.0 -0.5 2.0 0.3 1.3
Commuting to job workplace: Cycle 1.5 1.9 4.6 -1.5 -1.2 0.2 -2.1 -2.0 -0.9 1.4 -1.9 0.6 0.5 1.1 -0.8 -1.6 -1.6 1.3 -1.8 0.9 -0.0 0.4 1.0 -1.9 1.8 -1.7
Myopia 0.6 0.8 3.2 -0.9 0.8 1.4 -0.7 -0.3 -1.1 -0.0 -0.4 1.3 1.7 1.0 1.0 0.9 0.5 -0.8 -0.8 0.3 -0.3 0.9 -0.1 -0.1 1.8 -1.1
Vascular/heart problems diagnosed by doctor 0.6 1.7 9.4 -3.1 -0.3 1.1 -1.3 -1.7 -0.4 -0.1 -1.4 1.1 1.0 1.8 -1.1 -0.0 -0.1 1.2 -1.5 1.0 -0.8 1.6 0.1 -1.2 1.9 -1.3
Cholesterol lowering medication 1.8 2.7 8.7 3.0 0.3 -0.3 1.5 1.9 0.3 -1.2 1.4 -2.0 -1.7 -2.9 1.3 0.1 0.7 -1.5 2.3 -1.9 0.8 -0.5 -1.1 1.7 -2.7 1.8
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 2.3 1.2 1.0 0.5 1.5 -0.1 -0.2 0.7 0.1 1.4 -0.2 0.1 0.6 1.0 1.4 -0.7 0.3 0.6 0.2 0.8 0.3 0.8 0.7 0.0
Pain experienced in last month 0.2 0.3 1.6 -0.9 -0.6 -0.5 -0.3 -1.3 -0.0 0.1 -0.5 0.7 0.2 0.7 -0.3 0.0 -0.4 0.1 -0.9 -0.3 0.7 0.3 -0.6 -0.1 0.8 -0.1
Supplements: Calcium 1.7 1.8 6.9 -1.3 0.2 0.1 -0.7 -1.7 -0.9 2.1 -0.6 2.2 0.0 0.4 -1.5 -0.3 -0.2 2.0 -1.1 2.6 -1.0 1.1 2.1 -0.9 2.0 -0.3
Basal cell carcinoma (self-reported) 1.4 1.6 5.8 1.1 1.1 0.3 2.1 0.6 2.0 0.5 1.9 1.7 -0.2 -1.6 0.3 1.1 2.1 -0.7 2.4 0.7 -0.5 -0.4 0.6 1.4 0.7 1.2
Heart attack/myocardial infarction (self-reported) 0.5 0.6 3.2 0.7 0.1 0.9 0.0 0.5 0.7 0.4 0.9 -0.4 -0.0 -0.8 0.3 -1.7 -1.1 -0.8 0.1 -1.2 -0.6 -1.8 -0.2 -0.0 -0.6 0.0
Deep venous thrombosis (DVT) (self-reported) 2.3 2.9 8.8 1.4 3.0 2.0 2.5 1.6 2.5 0.6 1.7 0.9 0.6 -1.6 1.7 2.2 2.7 -1.0 3.0 0.4 0.5 -0.2 0.5 1.9 0.7 0.9
Heart disease (siblings) 0.2 0.3 0.9 0.8 -0.2 -0.8 -0.3 -0.1 0.4 -0.4 0.3 -0.5 0.1 -0.7 0.9 -0.5 0.1 -0.5 0.2 -1.0 -0.2 -0.6 -0.5 0.4 -0.5 0.6
Alcohol drinker status: Previous 1.7 1.9 6.7 2.6 0.5 0.1 0.8 2.0 -0.7 -1.6 1.1 -2.1 0.3 -0.3 0.8 -0.1 0.1 -1.9 0.9 -2.1 0.9 -2.3 -1.6 1.6 -1.7 0.9
Pack years of smoking 0.5 0.7 3.7 0.7 0.5 -0.5 0.6 1.3 0.4 -1.2 0.0 -0.9 -0.6 -0.5 1.0 0.8 0.3 -0.8 0.5 -0.9 1.9 0.4 -1.0 1.0 -0.9 0.7
Impedance of whole body 2.7 13.6 36.6 -5.0 -4.6 -1.7 -4.7 -6.0 -1.3 2.6 -2.6 1.6 0.1 2.3 -5.2 -3.2 -4.1 5.3 -4.8 3.8 -3.3 2.7 2.9 -4.9 2.5 -2.2
Leg fat mass (left) 1.2 4.6 21.8 4.0 2.1 0.4 2.4 3.2 -1.1 0.4 2.1 -0.5 -0.8 -3.0 1.8 1.9 2.7 -0.9 4.7 -0.2 0.3 -1.8 0.9 1.9 -2.3 2.0
Arm predicted mass (left) 1.5 7.7 24.9 4.3 4.6 3.1 3.6 4.1 -0.6 0.5 1.3 0.3 1.7 -1.3 3.6 2.8 4.7 -3.0 5.0 -0.7 0.5 -2.6 -0.1 2.5 -0.2 0.3