Best TWAS P=1.19e-14 · Best GWAS P=3.4e-10 conditioned to 0.252
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | GALC | 0.26 | 0.00 | enet | 26 | 0.04 | 3.4e-03 | 6.1 | -5.6 | 1.9e-08 | -0.51 | 0.03 | 0.87 | FALSE |
| 2 | GTEx | Colon Transverse | GALC | 0.28 | 0.06 | lasso | 17 | 0.19 | 2.3e-09 | -3.4 | -5.6 | 2.1e-08 | -0.65 | 0.49 | 0.50 | FALSE |
| 3 | GTEx | Heart Left Ventricle | GALC | 0.12 | 0.05 | enet | 21 | 0.04 | 2.4e-03 | 3.5 | -6.5 | 8.2e-11 | -0.72 | 0.07 | 0.89 | FALSE |
| 4 | GTEx | Thyroid | GALC | 0.14 | 0.02 | lasso | 13 | 0.04 | 8.0e-04 | 3.5 | -6.5 | 7.3e-11 | -0.74 | 0.31 | 0.67 | FALSE |
| 5 | METSIM | Adipose | GALC | 0.07 | 0.05 | lasso | 5 | 0.04 | 4.0e-07 | 6.3 | -6.1 | 1.3e-09 | -0.99 | 0.00 | 1.00 | FALSE |
| 6 | NTR | Blood | GALC | 0.02 | 0.00 | enet | 14 | 0.01 | 2.6e-04 | 6.1 | -5.2 | 1.8e-07 | -0.41 | 0.02 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | GPR65 | 0.09 | 0.01 | blup | 56 | 0.06 | 1.8e-07 | -4.8 | 5.9 | 3.7e-09 | 0.55 | 0.04 | 0.77 | TRUE |
| 8 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | GALC | 0.08 | 0.03 | blup | 130 | 0.05 | 8.1e-04 | 5.8 | -7.7 | 1.2e-14 | -0.71 | 0.02 | 0.82 | TRUE |
| 9 | The Cancer Genome Atlas | Rectum Adenocarcinoma | GALC | 0.23 | 0.14 | lasso | 4 | 0.14 | 3.4e-04 | 4.6 | -5.8 | 7.4e-09 | -0.89 | 0.01 | 0.78 | FALSE |