Best TWAS P=7.84e-08 · Best GWAS P=6.04e-07 conditioned to 0.000302
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | HMG20A | 0.04 | 0.00 | lasso | 4 | 0.01 | 0.0719 | -4.5 | 5.4 | 7.8e-08 | -0.28 | 0.04 | 0.41 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TSPAN3 | 0.03 | 0.01 | blup | 43 | 0.01 | 0.0082 | -4.9 | 5.2 | 2.2e-07 | -0.83 | 0.00 | 0.90 | FALSE |