Best TWAS P=1.02e-11 · Best GWAS P=6.61e-11 conditioned to 0.0191
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | FAM108C1 | 0.02 | 0.01 | bslmm | 542 | 0.01 | 6.1e-03 | -1.7 | 5.2 | 2.2e-07 | -0.38 | 0.09 | 0.28 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 5.8 | -5.4 | 6.2e-08 | 0.52 | 0.12 | 0.87 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -6.4 | -6.8 | 1.0e-11 | 0.72 | 0.01 | 0.87 | TRUE |