[Hub]/) : Traits : BMI : ← →

chr17:15,149,905-16,908,991

Best TWAS P=3.49e-12 · Best GWAS P=9.71e-12 conditioned to 0.159

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ADORA2B	0.06	0.07	blup	304	0.07	5.0e-09	-6.0	-6.5	5.7e-11	0.92	0.06	0.94	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ZSWIM7	0.25	0.53	lasso	4	0.52	2.2e-74	-6.1	-6.2	7.7e-10	0.97	0.25	0.75	FALSE
3	GTEx	Adipose Subcutaneous	ADORA2B	0.16	0.23	lasso	4	0.26	1.7e-21	-6.1	-6.3	2.1e-10	0.98	0.09	0.91	FALSE
4	GTEx	Adipose Visceral Omentum	TTC19	0.11	0.12	lasso	4	0.11	3.0e-06	-6.0	5.9	4.7e-09	-0.92	0.30	0.70	FALSE
5	GTEx	Adipose Visceral Omentum	ADORA2B	0.13	0.16	lasso	3	0.16	1.8e-08	-6.6	-6.5	6.6e-11	0.99	0.04	0.96	FALSE
6	GTEx	Adrenal Gland	TTC19	0.07	0.09	enet	11	0.09	5.0e-04	-5.9	6.0	2.3e-09	-0.93	0.16	0.67	FALSE
7	GTEx	Adrenal Gland	ADORA2B	0.11	0.03	enet	13	0.00	2.1e-01	-6.7	-5.2	1.5e-07	0.89	0.05	0.78	FALSE
8	GTEx	Artery Aorta	TTC19	0.06	0.00	lasso	3	0.00	7.1e-01	-6.2	6.4	1.6e-10	-0.87	0.09	0.25	FALSE
9	GTEx	Artery Aorta	ADORA2B	0.24	0.08	lasso	5	0.05	8.3e-04	-6.1	-6.3	3.4e-10	0.93	0.10	0.86	FALSE
10	GTEx	Artery Coronary	TTC19	0.19	0.07	enet	2	0.03	3.9e-02	-6.2	6.2	5.3e-10	-0.93	0.11	0.46	FALSE
11	GTEx	Artery Coronary	ADORA2B	0.14	0.12	lasso	2	0.11	2.0e-04	-6.1	-5.9	3.3e-09	0.96	0.04	0.95	FALSE
12	GTEx	Artery Tibial	ADORA2B	0.23	0.42	lasso	3	0.42	1.2e-35	-6.1	-6.3	4.0e-10	0.98	0.28	0.72	FALSE
13	GTEx	Artery Tibial	ZSWIM7	0.23	0.15	lasso	7	0.13	2.0e-10	-6.1	-6.1	1.2e-09	0.97	0.22	0.78	FALSE
14	GTEx	Brain Caudate basal ganglia	ZSWIM7	0.15	0.19	lasso	1	0.17	1.5e-05	-6.1	-6.1	1.0e-09	0.97	0.05	0.86	FALSE
15	GTEx	Brain Cerebellar Hemisphere	ADORA2B	0.16	0.00	lasso	9	-0.01	5.6e-01	-6.6	-6.5	1.0e-10	0.96	0.04	0.65	FALSE
16	GTEx	Brain Cerebellar Hemisphere	ZSWIM7	0.32	0.26	lasso	5	0.15	9.8e-05	-6.1	6.2	5.2e-10	-0.98	0.03	0.96	FALSE
17	GTEx	Brain Cerebellum	CENPV	0.15	0.08	enet	14	0.08	1.9e-03	-3.3	-5.5	4.1e-08	0.81	0.06	0.76	FALSE
18	GTEx	Brain Cerebellum	ZSWIM7	0.25	0.13	lasso	4	0.12	2.6e-04	-6.6	6.6	4.5e-11	-0.99	0.03	0.96	FALSE
19	GTEx	Brain Cortex	ZSWIM7	0.16	0.22	lasso	2	0.22	7.5e-07	-6.0	-6.2	5.5e-10	0.96	0.11	0.87	FALSE
20	GTEx	Brain Frontal Cortex BA9	ZSWIM7	0.15	0.21	lasso	3	0.20	6.3e-06	-6.6	-6.5	6.0e-11	0.99	0.04	0.95	FALSE
21	GTEx	Brain Hypothalamus	ZSWIM7	0.13	0.18	lasso	2	0.14	3.8e-04	-6.6	-6.4	1.2e-10	0.99	0.04	0.85	FALSE
22	GTEx	Brain Nucleus accumbens basal ganglia	NCOR1	0.17	0.06	lasso	5	0.07	6.1e-03	-6.6	-5.5	2.9e-08	0.95	0.04	0.63	FALSE
23	GTEx	Brain Nucleus accumbens basal ganglia	ZSWIM7	0.24	0.31	lasso	2	0.30	8.5e-09	-6.1	-6.2	7.9e-10	0.97	0.11	0.85	FALSE
24	GTEx	Breast Mammary Tissue	TTC19	0.07	0.05	enet	6	0.05	2.0e-03	-5.8	6.3	3.7e-10	-0.98	0.09	0.87	FALSE
25	GTEx	Breast Mammary Tissue	ADORA2B	0.10	0.15	lasso	2	0.12	5.9e-07	-6.1	-6.2	7.1e-10	0.97	0.04	0.96	FALSE
26	GTEx	Breast Mammary Tissue (Male)	TTC19	0.13	0.08	lasso	3	0.01	1.6e-01	-6.6	6.4	1.3e-10	-0.99	0.05	0.71	FALSE
27	GTEx	Cells EBV-transformed lymphocytes	TTC19	0.15	0.05	lasso	4	0.08	1.6e-03	-6.6	6.4	1.3e-10	-0.99	0.04	0.93	FALSE
28	GTEx	Cells Transformed fibroblasts	TTC19	0.13	0.21	lasso	5	0.24	9.6e-18	-6.0	6.0	1.9e-09	-0.95	0.57	0.43	FALSE
29	GTEx	Cells Transformed fibroblasts	ZSWIM7	0.47	0.27	lasso	3	0.24	2.4e-18	-6.1	-6.0	1.5e-09	0.97	0.45	0.55	FALSE
30	GTEx	Colon Transverse	TTC19	0.09	0.10	lasso	5	0.11	5.4e-06	-6.2	5.9	3.7e-09	-0.91	0.31	0.68	FALSE
31	GTEx	Esophagus Gastroesophageal Junction	ADORA2B	0.39	0.44	lasso	4	0.41	3.3e-16	-6.1	-6.2	5.4e-10	0.97	0.13	0.87	FALSE
32	GTEx	Esophagus Mucosa	ADORA2B	0.07	0.04	enet	17	0.07	1.9e-05	-6.6	-5.6	2.3e-08	0.86	0.04	0.95	FALSE
33	GTEx	Esophagus Muscularis	ADORA2B	0.29	0.46	lasso	2	0.45	4.8e-30	-6.1	-6.1	9.7e-10	0.97	0.32	0.68	FALSE
34	GTEx	Heart Atrial Appendage	ADORA2B	0.19	0.14	lasso	10	0.13	2.4e-06	-6.7	-6.7	1.9e-11	0.98	0.03	0.97	FALSE
35	GTEx	Heart Atrial Appendage	ZSWIM7	0.41	0.23	lasso	3	0.22	5.2e-10	-6.1	-6.0	2.0e-09	0.94	0.22	0.78	FALSE
36	GTEx	Heart Left Ventricle	ADORA2B	0.14	0.11	lasso	7	0.10	6.0e-06	-6.7	-6.0	1.4e-09	0.96	0.03	0.97	FALSE
37	GTEx	Heart Left Ventricle	ZSWIM7	0.12	0.22	lasso	2	0.22	4.4e-12	-6.1	-6.2	4.8e-10	0.97	0.13	0.87	FALSE
38	GTEx	Liver	ADORA2B	0.15	0.15	lasso	6	0.10	8.2e-04	-6.1	-6.2	5.7e-10	0.98	0.04	0.89	FALSE
39	GTEx	Lung	TTC19	0.07	0.10	lasso	3	0.10	4.0e-08	-6.0	6.1	1.0e-09	-0.96	0.33	0.67	FALSE
40	GTEx	Lung	ADORA2B	0.19	0.09	lasso	4	0.07	3.2e-06	-6.1	-6.3	2.3e-10	0.97	0.04	0.96	FALSE
41	GTEx	Lung	ZSWIM7	0.05	0.06	lasso	1	0.05	1.3e-04	-6.1	6.1	1.0e-09	-0.97	0.07	0.84	FALSE
42	GTEx	Muscle Skeletal	TTC19	0.03	0.04	lasso	3	0.02	2.9e-03	-5.9	5.5	2.9e-08	-0.87	0.40	0.40	FALSE
43	GTEx	Muscle Skeletal	ADORA2B	0.27	0.44	lasso	3	0.45	5.3e-48	-6.1	-6.3	2.8e-10	0.98	0.40	0.60	FALSE
44	GTEx	Muscle Skeletal	ZSWIM7	0.22	0.42	enet	15	0.42	9.6e-45	-6.1	-6.5	1.0e-10	0.98	0.22	0.78	FALSE
45	GTEx	Nerve Tibial	TTC19	0.09	0.11	lasso	3	0.11	2.3e-08	-6.3	5.6	1.9e-08	-0.89	0.17	0.83	FALSE
46	GTEx	Nerve Tibial	ADORA2B	0.29	0.36	lasso	5	0.34	8.2e-25	-6.1	-6.4	1.2e-10	0.97	0.42	0.58	FALSE
47	GTEx	Ovary	ADORA2B	0.58	0.64	lasso	1	0.64	4.4e-20	-6.1	-6.1	1.0e-09	0.97	0.18	0.82	FALSE
48	GTEx	Pancreas	TTC19	0.12	0.09	enet	9	0.07	8.5e-04	-6.0	6.2	4.6e-10	-0.86	0.18	0.51	FALSE
49	GTEx	Pancreas	ADORA2B	0.12	0.16	enet	9	0.14	1.5e-06	-6.6	-6.4	1.9e-10	0.99	0.03	0.97	FALSE
50	GTEx	Skin Not Sun Exposed Suprapubic	TTC19	0.21	0.18	lasso	5	0.18	6.3e-10	-6.0	6.1	1.3e-09	-0.92	0.50	0.50	FALSE
51	GTEx	Skin Not Sun Exposed Suprapubic	ADORA2B	0.15	0.13	lasso	3	0.12	3.8e-07	-6.7	-6.7	2.0e-11	0.99	0.03	0.97	FALSE
52	GTEx	Skin Not Sun Exposed Suprapubic	ZSWIM7	0.17	0.17	lasso	4	0.19	1.1e-10	-6.6	6.5	1.0e-10	-0.99	0.03	0.97	FALSE
53	GTEx	Skin Sun Exposed Lower leg	TTC19	0.08	0.18	lasso	3	0.17	6.9e-14	-6.2	6.3	2.3e-10	-0.94	0.35	0.65	FALSE
54	GTEx	Skin Sun Exposed Lower leg	ADORA2B	0.12	0.17	lasso	4	0.17	3.1e-14	-6.6	-6.5	5.7e-11	0.99	0.03	0.97	FALSE
55	GTEx	Skin Sun Exposed Lower leg	ZSWIM7	0.12	0.08	enet	16	0.10	2.1e-08	-6.6	6.3	3.5e-10	-0.92	0.06	0.94	FALSE
56	GTEx	Spleen	TTC19	0.28	0.06	enet	12	0.03	7.0e-02	-6.2	5.6	2.5e-08	-0.88	0.14	0.56	FALSE
57	GTEx	Spleen	ADORA2B	0.23	0.27	enet	10	0.24	7.4e-07	-6.3	-6.7	2.2e-11	0.97	0.05	0.95	FALSE
58	GTEx	Spleen	ZSWIM7	0.37	0.39	lasso	7	0.40	2.8e-11	-6.5	6.4	1.3e-10	-0.99	0.04	0.96	FALSE
59	GTEx	Stomach	TTC19	0.14	0.12	enet	13	0.09	2.8e-05	-6.2	5.3	8.6e-08	-0.83	0.51	0.46	FALSE
60	GTEx	Testis	NCOR1	0.15	0.00	enet	27	0.08	2.8e-04	2.3	-5.2	1.6e-07	0.64	0.06	0.81	FALSE
61	GTEx	Testis	ZSWIM7	0.34	0.59	lasso	8	0.58	2.4e-31	-6.1	6.2	5.2e-10	-0.97	0.15	0.85	FALSE
62	GTEx	Thyroid	ADORA2B	0.35	0.55	lasso	2	0.54	9.1e-49	-6.1	-6.1	9.6e-10	0.97	0.46	0.54	FALSE
63	GTEx	Whole Blood	NCOR1	0.09	0.12	lasso	2	0.11	2.4e-10	-5.5	-5.5	4.6e-08	0.89	0.68	0.32	FALSE
64	GTEx	Whole Blood	ADORA2B	0.08	0.00	lasso	5	0.00	2.5e-01	-6.3	-6.9	6.9e-12	0.85	0.04	0.68	FALSE
65	METSIM	Adipose	ADORA2B	0.10	0.20	lasso	3	0.20	4.2e-29	-6.4	-6.4	1.3e-10	0.99	0.04	0.96	FALSE
66	METSIM	Adipose	TTC19	0.09	0.21	lasso	4	0.21	4.1e-30	-6.0	6.0	2.8e-09	-0.93	0.50	0.50	FALSE
67	NTR	Blood	ADORA2B	0.02	0.03	lasso	1	0.03	1.3e-10	-6.1	-6.1	1.0e-09	0.97	0.05	0.95	FALSE
68	NTR	Blood	ZSWIM7	0.02	0.03	lasso	5	0.03	9.3e-10	-5.9	6.1	8.5e-10	-0.97	0.04	0.96	FALSE
69	ROSMAP	Brain Pre-frontal Cortex	TTC19	0.14	0.24	lasso	10	0.27	1.2e-34	-6.8	-6.5	1.0e-10	0.95	0.02	0.98	FALSE
70	ROSMAP	Brain Pre-frontal Cortex	ADORA2B	0.09	0.11	lasso	5	0.10	5.7e-13	-6.4	-6.3	3.0e-10	0.98	0.04	0.96	FALSE
71	ROSMAP	Brain Pre-frontal Cortex	ZSWIM7	0.36	0.71	lasso	2	0.70	1.1e-128	-6.1	-6.2	7.8e-10	0.97	0.34	0.66	FALSE
72	YFS	Blood	ADORA2B	0.17	0.04	enet	38	0.07	7.7e-21	-6.0	-5.6	2.4e-08	0.66	0.14	0.86	FALSE
73	YFS	Blood	NCOR1	0.02	0.04	lasso	5	0.04	2.6e-13	-5.8	-5.2	2.4e-07	0.91	0.58	0.42	FALSE
74	YFS	Blood	PIGL	0.02	0.02	blup	279	0.02	1.5e-06	-4.2	-7.0	3.5e-12	0.88	0.17	0.83	TRUE
75	YFS	Blood	ZSWIM7	0.63	0.76	bslmm	272	0.76	0.0e+00	-6.1	6.1	1.0e-09	-0.96	0.46	0.54	FALSE
76	The Cancer Genome Atlas	Breast Invasive Carcinoma	ADORA2B	0.07	0.14	lasso	1	0.14	9.0e-27	-6.1	-6.1	1.0e-09	0.97	0.06	0.94	FALSE
77	The Cancer Genome Atlas	Breast Invasive Carcinoma	PIGL	0.02	0.01	blup	71	0.02	3.5e-04	-4.8	-5.4	6.1e-08	0.90	0.07	0.86	FALSE
78	The Cancer Genome Atlas	Breast Invasive Carcinoma	TTC19	0.03	0.02	lasso	4	0.02	2.7e-04	-5.9	5.2	1.9e-07	-0.69	0.12	0.49	FALSE
79	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZSWIM7	0.06	0.10	lasso	2	0.09	1.4e-17	-6.5	-6.5	7.4e-11	0.99	0.01	0.99	FALSE
80	The Cancer Genome Atlas	Colon Adenocarcinoma	ZSWIM7	0.04	0.02	blup	44	0.03	5.0e-03	-6.7	-6.4	1.9e-10	0.99	0.02	0.80	FALSE
81	The Cancer Genome Atlas	Glioblastoma Multiforme	ZSWIM7	0.12	0.11	blup	43	0.10	6.9e-04	-5.9	-6.2	4.2e-10	0.96	0.03	0.81	FALSE
82	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TTC19	0.03	0.04	enet	11	0.04	1.0e-05	-5.7	6.2	4.6e-10	-0.90	0.10	0.89	FALSE
83	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ZSWIM7	0.12	0.10	lasso	3	0.11	1.5e-12	-6.1	-5.9	4.0e-09	0.92	0.14	0.86	FALSE
84	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADORA2B	0.11	0.09	lasso	5	0.08	4.3e-09	-6.1	-6.2	6.6e-10	0.97	0.02	0.98	FALSE
85	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TTC19	0.04	0.06	lasso	2	0.06	7.7e-07	-5.9	5.9	3.2e-09	-0.91	0.09	0.91	FALSE
86	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZSWIM7	0.14	0.25	lasso	7	0.24	3.3e-27	-6.1	-6.2	5.2e-10	0.98	0.04	0.96	FALSE
87	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ADORA2B	0.28	0.24	enet	14	0.27	7.3e-16	-6.1	-6.7	2.2e-11	0.95	0.02	0.98	FALSE
88	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TTC19	0.07	0.08	lasso	2	0.07	5.2e-05	-6.0	6.1	9.2e-10	-0.92	0.06	0.88	FALSE
89	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ZSWIM7	0.10	0.15	lasso	1	0.14	1.6e-08	-5.7	-5.7	9.3e-09	0.86	0.11	0.89	FALSE
90	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADORA2B	0.06	0.10	lasso	2	0.10	5.9e-12	-6.1	-5.7	1.1e-08	0.95	0.04	0.96	FALSE
91	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCOR1	0.03	0.04	blup	97	0.04	8.1e-06	-6.5	-6.5	6.6e-11	0.99	0.04	0.96	FALSE
92	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZSWIM7	0.19	0.32	lasso	4	0.32	5.9e-37	-6.1	-6.3	2.9e-10	0.98	0.03	0.97	FALSE
93	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ADORA2B	0.13	0.17	blup	37	0.16	8.2e-08	-6.6	-6.8	7.2e-12	0.96	0.01	0.99	FALSE
94	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	TTC19	0.10	0.09	lasso	7	0.08	1.9e-04	-5.9	5.7	1.6e-08	-0.90	0.08	0.79	FALSE
95	The Cancer Genome Atlas	Lung Adenocarcinoma	ZSWIM7	0.05	0.05	blup	48	0.05	3.3e-06	-6.1	-6.7	1.6e-11	0.98	0.02	0.98	FALSE
96	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TTC19	0.03	0.03	enet	8	0.03	2.0e-04	-6.5	6.5	8.7e-11	-0.97	0.03	0.96	FALSE
97	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZSWIM7	0.04	0.06	lasso	1	0.06	4.1e-07	-6.1	-6.1	1.0e-09	0.97	0.02	0.97	FALSE
98	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ADORA2B	0.10	0.07	enet	9	0.08	5.0e-06	-6.1	-6.3	3.2e-10	0.94	0.01	0.98	FALSE
99	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ZSWIM7	0.10	0.04	lasso	5	0.04	1.6e-03	-6.3	-6.4	1.9e-10	0.95	0.03	0.96	FALSE
100	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	TTC19	0.10	0.11	lasso	1	0.09	9.6e-05	-6.4	6.4	1.3e-10	-0.99	0.04	0.95	FALSE
101	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ZSWIM7	0.08	0.02	blup	45	0.03	1.8e-02	-5.9	-5.5	4.0e-08	0.93	0.03	0.80	FALSE
102	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ADORA2B	0.15	0.16	enet	12	0.18	1.6e-07	-6.1	-6.3	2.5e-10	0.93	0.01	0.99	FALSE
103	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ZSWIM7	0.13	0.12	lasso	2	0.13	6.5e-06	-6.1	-6.1	1.2e-09	0.97	0.03	0.97	FALSE
104	The Cancer Genome Atlas	Prostate Adenocarcinoma	ADORA2B	0.14	0.19	lasso	3	0.20	8.0e-21	-6.1	-6.2	5.9e-10	0.96	0.02	0.98	FALSE
105	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZSWIM7	0.15	0.25	enet	13	0.26	2.0e-27	-6.6	-6.6	5.2e-11	0.99	0.01	0.99	FALSE
106	The Cancer Genome Atlas	Skin Cutaneous Melanoma	ZSWIM7	0.27	0.26	blup	44	0.30	1.2e-08	-6.5	-6.2	4.7e-10	0.96	0.01	0.98	FALSE
107	The Cancer Genome Atlas	Stomach Adenocarcinoma	ZSWIM7	0.14	0.15	lasso	3	0.15	4.1e-11	-6.1	-6.4	2.0e-10	0.97	0.02	0.98	FALSE
108	The Cancer Genome Atlas	Thyroid Carcinoma	ADORA2B	0.12	0.23	lasso	7	0.24	1.5e-23	-6.1	-6.3	2.6e-10	0.97	0.01	0.99	FALSE
109	The Cancer Genome Atlas	Thyroid Carcinoma	TTC19	0.16	0.21	lasso	5	0.20	1.4e-19	-6.1	6.0	1.9e-09	-0.92	0.32	0.68	FALSE
110	The Cancer Genome Atlas	Thyroid Carcinoma	ZSWIM7	0.28	0.45	lasso	7	0.46	2.5e-50	-6.1	-6.2	5.0e-10	0.97	0.05	0.95	FALSE