[Hub]/) : Traits : BMI :

chr17:20,350,968-22,010,013

Best TWAS P=2.42e-17 · Best GWAS P=3.03e-20 conditioned to 4.48e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Muscularis C17orf103 0.16 0.06 lasso 5 0.06 2.1e-04 -5.2 5.7 1.5e-08 0.35 0.20 0.40 FALSE
2 GTEx Lung C17orf103 0.08 0.01 enet 11 0.04 6.6e-04 6.3 7.3 2.7e-13 0.53 0.18 0.40 FALSE
3 GTEx Skin Sun Exposed Lower leg C17orf103 0.11 0.02 enet 15 0.07 1.0e-06 3.5 6.5 1.1e-10 0.32 0.28 0.32 FALSE
4 GTEx Testis C17orf103 0.15 0.21 enet 4 0.19 7.1e-09 -5.2 5.9 3.8e-09 0.35 0.96 0.02 FALSE
5 GTEx Thyroid DHRS7B 0.17 0.02 enet 22 0.11 1.2e-08 -4.3 -5.5 3.0e-08 -0.28 0.71 0.17 FALSE
6 GTEx Thyroid KCNJ12 0.36 0.23 lasso 5 0.25 2.9e-19 -6.7 -8.5 2.4e-17 -0.80 0.66 0.34 TRUE
7 METSIM Adipose MAP2K3 0.08 0.02 blup 211 0.03 6.0e-05 -5.0 5.6 2.0e-08 0.53 0.08 0.87 FALSE
8 NTR Blood C17orf103 0.02 0.02 lasso 2 0.02 1.6e-07 -5.1 5.5 3.7e-08 0.34 0.98 0.01 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma C17orf103 0.08 0.01 blup 44 0.01 3.2e-02 -5.2 5.3 1.0e-07 0.42 0.03 0.46 FALSE