[Hub]/) : Traits : BMI : ← →

chr17:60,930,216-62,599,864

Best TWAS P=1.8e-10 · Best GWAS P=2.01e-09 conditioned to 0.000203

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	MAP3K3	0.09	0.07	lasso	6	0.07	3.5e-06	-5.8	-5.7	1.5e-08	0.98	0.04	0.96	FALSE
2	GTEx	Adipose Visceral Omentum	MAP3K3	0.10	0.04	enet	12	0.05	9.0e-04	-5.7	-6.1	9.2e-10	0.83	0.04	0.87	FALSE
3	GTEx	Artery Tibial	DDX42	0.13	0.14	lasso	5	0.15	9.1e-12	-5.7	5.5	3.8e-08	-0.93	0.04	0.96	FALSE
4	GTEx	Brain Nucleus accumbens basal ganglia	DDX42	0.23	0.04	lasso	12	0.07	8.1e-03	-5.7	5.7	1.0e-08	-0.83	0.04	0.82	FALSE
5	GTEx	Brain Putamen basal ganglia	DDX42	0.16	0.04	lasso	4	0.06	1.5e-02	4.5	5.8	6.1e-09	-0.53	0.06	0.50	FALSE
6	GTEx	Breast Mammary Tissue	DCAF7	0.08	0.00	enet	18	0.05	1.1e-03	-5.7	-6.0	1.6e-09	0.52	0.04	0.56	FALSE
7	GTEx	Breast Mammary Tissue	MAP3K3	0.10	0.11	lasso	8	0.08	8.9e-05	-5.7	-5.8	6.5e-09	1.00	0.04	0.96	FALSE
8	GTEx	Breast Mammary Tissue (Male)	MAP3K3	0.12	0.14	lasso	2	0.07	1.2e-02	-6.0	-5.8	7.9e-09	0.95	0.04	0.76	FALSE
9	GTEx	Breast Mammary Tissue (Female)	DCAF7	0.10	0.02	lasso	3	0.00	4.4e-01	-5.8	-6.3	3.9e-10	0.94	0.03	0.54	FALSE
10	GTEx	Breast Mammary Tissue (Female)	MAP3K3	0.07	0.01	lasso	1	0.00	4.1e-01	-5.8	-5.8	8.3e-09	0.99	0.03	0.48	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	DDX42	0.11	0.14	lasso	2	0.12	1.3e-04	-5.8	5.8	5.9e-09	-0.98	0.04	0.90	FALSE
12	GTEx	Esophagus Mucosa	DDX42	0.08	0.06	lasso	3	0.09	1.3e-06	-5.7	5.6	2.4e-08	-0.95	0.04	0.95	FALSE
13	GTEx	Esophagus Muscularis	DCAF7	0.08	0.06	lasso	7	0.05	6.7e-04	-5.9	-5.8	4.8e-09	0.98	0.03	0.95	FALSE
14	GTEx	Esophagus Muscularis	MAP3K3	0.07	0.02	enet	8	0.02	3.0e-02	-5.8	-5.4	6.0e-08	0.87	0.06	0.89	FALSE
15	GTEx	Lung	MAP3K3	0.07	0.07	lasso	2	0.06	2.8e-05	-6.0	-6.0	1.6e-09	1.00	0.03	0.97	FALSE
16	GTEx	Muscle Skeletal	PSMC5	0.04	0.02	lasso	2	0.02	3.1e-03	-5.9	-5.5	3.5e-08	0.78	0.07	0.87	FALSE
17	GTEx	Nerve Tibial	MAP3K3	0.07	0.10	lasso	2	0.08	4.1e-06	-5.7	-5.7	9.7e-09	0.99	0.04	0.96	FALSE
18	GTEx	Pancreas	DDX42	0.17	0.18	lasso	3	0.16	3.6e-07	-5.8	5.7	1.5e-08	-0.96	0.04	0.96	FALSE
19	GTEx	Pituitary	MAP3K3	0.11	0.07	lasso	6	0.04	3.5e-02	-5.8	-6.1	1.1e-09	0.98	0.05	0.63	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	MAP3K3	0.12	0.13	enet	10	0.15	1.8e-08	-5.7	-5.7	1.5e-08	0.99	0.04	0.96	FALSE
21	GTEx	Skin Sun Exposed Lower leg	DDX42	0.07	0.04	lasso	4	0.05	2.5e-05	-5.4	5.4	6.3e-08	-0.96	0.04	0.96	FALSE
22	GTEx	Skin Sun Exposed Lower leg	MAP3K3	0.08	0.08	lasso	3	0.08	6.8e-07	-5.7	-5.6	1.9e-08	0.98	0.04	0.96	FALSE
23	GTEx	Spleen	FTSJ3	0.19	0.07	lasso	3	0.06	1.2e-02	-5.8	-5.5	4.4e-08	0.88	0.09	0.76	FALSE
24	GTEx	Spleen	MAP3K3	0.21	0.14	lasso	10	0.10	1.4e-03	-5.7	-5.9	3.5e-09	0.98	0.04	0.92	FALSE
25	GTEx	Stomach	DCAF7	0.24	0.00	enet	33	0.08	1.2e-04	-1.5	-6.4	1.8e-10	0.41	0.04	0.50	TRUE
26	GTEx	Testis	PSMC5	0.14	0.13	lasso	6	0.14	6.0e-07	-5.4	5.6	1.8e-08	-0.98	0.04	0.96	FALSE
27	YFS	Blood	SMARCD2	0.03	0.04	lasso	7	0.05	7.6e-15	-5.4	-5.4	7.6e-08	0.92	0.04	0.96	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DDX42	0.04	0.02	blup	51	0.03	3.9e-04	-5.4	5.2	2.2e-07	-0.91	0.01	0.96	FALSE
29	The Cancer Genome Atlas	Brain Lower Grade Glioma	DDX42	0.06	0.04	blup	51	0.06	7.9e-08	3.2	5.2	2.5e-07	-0.83	0.07	0.93	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	SMARCD2	0.08	0.04	blup	28	0.04	5.1e-05	-5.4	-5.5	5.1e-08	0.97	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Lung Adenocarcinoma	SMARCD2	0.04	0.02	blup	28	0.01	1.6e-02	-5.8	-5.5	2.9e-08	0.95	0.00	0.83	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	DDX42	0.07	0.07	enet	11	0.07	9.2e-08	-5.8	5.6	2.4e-08	-0.94	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	MAP3K3	0.02	0.02	blup	52	0.01	1.4e-02	-6.0	-5.8	6.7e-09	0.98	0.02	0.74	FALSE