TWAS hub - DDX42

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0930	0.0380	1.4e-05	0.060	NA	0.044	NA	0.050	1.1e-05	NA	1.7e-04	NA	5.9e-05
2	GTEx	Artery Aorta	0.0840	0.0410	5.6e-04	0.010	NA	0.010	NA	0.008	9.1e-02	NA	9.1e-02	NA	1.1e-01
3	GTEx	Artery Tibial	0.1281	0.0393	1.3e-10	0.136	NA	0.140	NA	0.149	8.2e-11	NA	4.1e-11	NA	9.1e-12
4	GTEx	Brain Cerebellum	0.1180	0.0610	5.9e-03	-0.003	NA	0.023	NA	-0.003	4.0e-01	NA	7.0e-02	NA	4.0e-01
5	GTEx	Brain Hypothalamus	0.1510	0.0730	5.0e-03	0.181	NA	0.044	NA	0.089	5.0e-05	NA	3.4e-02	NA	4.2e-03
6	GTEx	Brain Nucleus accumbens basal ganglia	0.2320	0.0930	1.8e-03	0.042	NA	0.017	NA	0.065	2.8e-02	NA	1.1e-01	NA	8.1e-03
7	GTEx	Brain Putamen basal ganglia	0.1610	0.0660	2.1e-03	0.041	NA	0.038	NA	0.060	3.9e-02	NA	4.5e-02	NA	1.5e-02
8	GTEx	Cells EBV-transformed lymphocytes	0.1110	0.0560	7.8e-03	0.141	NA	0.047	NA	0.116	2.4e-05	NA	1.2e-02	NA	1.3e-04
9	GTEx	Colon Transverse	0.1890	0.0720	7.4e-06	0.065	NA	0.098	NA	0.114	4.9e-04	NA	2.1e-05	NA	4.4e-06
10	GTEx	Esophagus Mucosa	0.0770	0.0320	4.2e-05	0.061	NA	0.087	NA	0.090	6.6e-05	NA	1.9e-06	NA	1.3e-06
11	GTEx	Esophagus Muscularis	0.0700	0.0330	5.7e-04	0.016	NA	0.006	NA	0.005	3.4e-02	NA	1.3e-01	NA	1.5e-01
12	GTEx	Lung	0.0571	0.0261	2.3e-04	0.039	NA	0.039	NA	0.031	5.4e-04	NA	5.8e-04	NA	2.0e-03
13	GTEx	Muscle Skeletal	0.0315	0.0148	1.4e-03	0.048	NA	0.048	NA	0.047	1.8e-05	NA	1.8e-05	NA	1.9e-05
14	GTEx	Nerve Tibial	0.0749	0.0295	7.9e-06	0.083	NA	0.062	NA	0.061	1.8e-06	NA	3.7e-05	NA	4.1e-05
15	GTEx	Pancreas	0.1720	0.0570	4.6e-07	0.180	NA	0.121	NA	0.157	4.8e-08	NA	9.2e-06	NA	3.6e-07
16	GTEx	Skin Not Sun Exposed Suprapubic	0.1670	0.0540	1.9e-07	0.095	NA	0.083	NA	0.105	6.9e-06	NA	2.8e-05	NA	2.4e-06
17	GTEx	Skin Sun Exposed Lower leg	0.0710	0.0270	1.7e-05	0.045	NA	0.045	NA	0.055	1.3e-04	NA	1.2e-04	NA	2.5e-05
18	GTEx	Stomach	0.1520	0.0770	1.5e-03	0.008	NA	0.043	NA	0.015	1.3e-01	NA	4.0e-03	NA	6.0e-02
19	GTEx	Thyroid	0.0690	0.0310	3.0e-04	0.069	NA	0.025	NA	0.050	5.5e-06	NA	4.5e-03	NA	1.1e-04
20	GTEx	Whole Blood	0.0540	0.0280	1.7e-03	0.027	NA	0.008	NA	0.014	1.5e-03	NA	6.0e-02	NA	1.7e-02
21	TCGA	Colon Adenocarcinoma	0.0420	0.0330	5.3e-03	0.011	0.023	0.011	NA	0.010	6.8e-02	1.6e-02	7.6e-02	NA	8.6e-02
22	TCGA	Kidney Renal Clear Cell Carcinoma	0.0362	0.0245	7.3e-04	0.016	0.028	0.023	NA	0.020	5.1e-03	3.9e-04	1.2e-03	NA	2.3e-03
23	TCGA	Brain Lower Grade Glioma	0.0606	0.0346	1.7e-07	0.038	0.064	0.063	NA	0.056	3.2e-05	7.9e-08	1.2e-07	NA	5.4e-07
24	TCGA	Prostate Adenocarcinoma	0.0733	0.0418	4.5e-07	0.070	0.068	0.069	NA	0.069	7.4e-08	1.4e-07	9.2e-08	NA	1.1e-07
25	TCGA	Stomach Adenocarcinoma	0.0410	0.0320	2.9e-03	0.022	0.042	0.035	NA	0.029	9.8e-03	5.2e-04	1.4e-03	NA	3.4e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Height	14.5	280.0	702.2	-3.6	-3.8	-22.1	-14.4	-23.5	-24.6	-14.9	-26.5	-16.4	-23.5	-6.8	-14.7	-0.2	-5.9	-23.5	-14.9	-23.7	-6.6	-4.8	-2.5	-13.1	-19.8	-17.5	-22.2	-17.4
Standing height	14.1	139.4	361.0	-1.9	-2.2	-15.8	-9.2	-16.7	-17.8	-9.4	-19.0	-12.2	-16.9	-4.5	-10.1	0.3	-3.9	-16.7	-10.5	-16.9	-4.2	-3.0	-1.5	-9.0	-14.1	-12.2	-15.7	-12.1
Comparative height size at age 10	11.4	62.6	161.3	-1.1	-1.4	-10.5	-5.7	-11.6	-12.0	-7.0	-12.7	-7.7	-11.1	-2.9	-6.7	0.6	-2.6	-11.1	-6.9	-11.5	-2.8	-2.0	-1.1	-6.0	-9.5	-8.2	-10.5	-8.2
Forced vital capacity (FVC)	10.3	39.7	114.5	-0.6	-0.5	-8.7	-3.2	-8.6	-10.5	-3.6	-10.7	-6.5	-9.3	-1.8	-4.5	1.0	-1.5	-9.2	-5.5	-9.4	-2.8	-1.0	-0.4	-4.3	-7.7	-6.2	-8.6	-6.2
Forced vital capacity (FVC), Best measure	8.9	32.4	100.0	-0.3	0.1	-7.8	-2.9	-8.3	-10.0	-2.6	-10.0	-5.3	-8.4	-1.3	-3.6	1.6	-0.7	-8.3	-4.7	-8.7	-2.1	-0.2	0.3	-3.5	-6.8	-5.4	-7.7	-5.4
Forced expiratory volume in 1-second (FEV1), predicted	8.9	18.5	50.8	-0.9	-1.2	-5.7	-3.2	-5.7	-7.1	-2.6	-6.7	-4.6	-6.1	-2.0	-3.6	-0.5	-1.7	-6.0	-4.1	-5.8	-1.2	-1.5	-0.9	-3.5	-5.0	-4.6	-5.7	-4.5
Cholesterol lowering medication	8.8	12.9	20.3	3.1	2.9	4.0	3.8	3.3	4.5	2.3	3.9	4.0	4.0	3.3	3.9	2.6	3.0	4.0	3.8	3.9	3.6	2.9	2.8	3.7	4.0	3.9	4.0	3.9
Trunk fat-free mass	7.3	41.7	139.2	1.4	2.0	-8.6	-4.3	-9.8	-10.7	-4.9	-11.8	-5.9	-9.6	-0.8	-4.6	3.0	0.8	-9.5	-4.2	-9.8	-1.9	1.4	2.5	-3.0	-7.2	-5.6	-8.6	-5.5
Trunk predicted mass	7.2	41.0	139.2	1.4	2.1	-8.5	-4.2	-9.7	-10.6	-4.8	-11.8	-5.8	-9.5	-0.7	-4.5	3.1	0.9	-9.4	-4.1	-9.7	-1.9	1.5	2.6	-2.9	-7.2	-5.5	-8.5	-5.4
Hair/balding pattern: Pattern 3	7.1	10.6	12.9	-3.0	-3.3	-3.4	-3.3	-3.4	-2.8	-2.5	-2.8	-3.6	-3.3	-2.7	-3.2	-3.2	-3.5	-3.3	-3.6	-3.1	-2.8	-3.5	-3.4	-3.5	-3.5	-3.5	-3.4	-3.5
Sitting height	6.9	48.7	166.4	2.0	1.9	-9.4	-4.5	-10.1	-11.6	-5.2	-12.9	-6.0	-10.5	0.4	-4.0	3.3	0.6	-10.4	-4.7	-10.6	-0.0	1.3	2.7	-3.6	-7.9	-6.3	-9.5	-6.2
Body Mass Index (BMI) (2010)	6.8	9.3	15.3	3.1	2.6	3.3	3.9	3.6	2.4	3.5	3.3	3.0	3.3	2.7	3.0	2.2	2.4	3.3	2.9	3.5	2.8	2.4	2.3	2.9	3.2	3.2	3.3	3.2
Cardiovascular Disease	6.7	22.0	52.0	3.5	4.6	4.8	6.1	3.9	2.9	7.2	4.0	4.7	4.5	4.6	5.3	3.8	4.7	4.7	4.8	4.4	2.4	4.7	4.2	5.2	4.8	5.2	4.8	5.2
Worry too long after embarrassment	6.7	11.2	21.0	-3.7	-3.7	-3.0	-2.9	-3.0	-1.7	-3.7	-2.3	-2.1	-2.7	-3.0	-4.2	-3.0	-3.8	-2.9	-3.6	-3.1	-4.6	-3.7	-3.6	-3.9	-3.3	-3.7	-3.1	-3.7
Forced expiratory volume in 1-second (FEV1)	6.5	22.0	72.6	0.7	0.7	-6.5	-1.8	-6.4	-8.5	-1.8	-8.4	-4.8	-7.1	-0.7	-2.6	1.8	-0.2	-6.9	-3.7	-7.2	-1.2	0.2	0.7	-2.7	-5.6	-4.4	-6.4	-4.3
Whole body fat-free mass	6.2	35.4	116.6	1.1	1.7	-7.9	-3.9	-9.1	-9.8	-4.3	-10.8	-5.5	-8.9	-1.0	-4.3	2.7	0.7	-8.7	-3.9	-9.0	-2.3	1.2	2.2	-2.8	-6.7	-5.1	-7.9	-5.1
Medication for cholesterol	6.2	9.3	15.1	-2.6	-2.7	-3.3	-3.9	-2.7	-2.9	-3.7	-3.0	-2.9	-3.3	-2.4	-3.4	-2.5	-2.8	-3.2	-3.1	-3.3	-2.6	-2.7	-2.5	-3.2	-3.2	-3.3	-3.3	-3.3
Whole body water mass	6.1	34.8	116.6	1.2	1.8	-7.8	-3.8	-9.0	-9.8	-4.2	-10.8	-5.4	-8.8	-0.9	-4.3	2.8	0.8	-8.6	-3.8	-9.0	-2.2	1.3	2.3	-2.7	-6.6	-5.0	-7.8	-5.0
Blood White Count	5.5	40.8	54.6	5.6	5.9	6.9	6.6	6.4	6.0	6.0	6.1	7.0	6.7	6.4	7.4	5.1	6.0	6.6	6.7	6.8	4.9	5.9	5.7	6.8	6.8	7.0	6.8	7.0
High cholesterol (Self-reported)	5.4	9.6	13.5	2.9	2.8	3.3	3.4	2.7	2.7	3.4	2.9	3.5	3.3	3.1	3.7	2.5	2.9	3.2	3.2	2.9	3.3	2.9	2.7	3.1	3.2	3.2	3.2	3.2
Forced expiratory volume in 1-second (FEV1), Best measure	5.3	17.0	62.1	0.8	1.1	-5.6	-1.5	-6.1	-7.9	-1.1	-7.5	-3.5	-6.1	-0.3	-2.0	2.2	0.4	-6.1	-3.0	-6.5	-0.8	0.8	1.2	-2.0	-4.8	-3.6	-5.5	-3.6
Qualifications: College or University degree	5.2	16.4	23.0	-3.1	-3.6	-4.7	-3.7	-4.0	-4.3	-3.7	-4.5	-3.9	-4.6	-3.0	-4.0	-3.4	-3.7	-4.6	-4.4	-4.8	-2.2	-3.6	-3.4	-4.2	-4.7	-4.5	-4.7	-4.6
Leg fat-free mass (right)	5.2	27.5	88.5	0.7	1.3	-7.0	-3.3	-7.9	-8.8	-3.6	-9.4	-5.1	-7.8	-1.2	-4.0	2.2	0.3	-7.6	-3.5	-7.9	-2.6	0.8	1.5	-2.5	-6.0	-4.6	-7.0	-4.5
High blood pressure (siblings)	5.1	7.4	12.5	2.9	3.3	2.5	2.7	2.1	0.6	3.3	1.6	2.5	2.3	2.9	3.0	3.5	3.2	2.2	2.8	2.3	2.5	3.2	3.0	3.2	2.5	3.0	2.3	3.0
Leg predicted mass (right)	5.1	27.2	87.4	0.7	1.3	-7.0	-3.2	-7.9	-8.7	-3.5	-9.3	-5.1	-7.7	-1.2	-4.0	2.2	0.4	-7.6	-3.5	-7.9	-2.7	0.8	1.6	-2.5	-5.9	-4.5	-6.9	-4.5
Arm fat-free mass (right)	5.0	25.7	90.6	1.6	2.2	-6.7	-2.9	-7.8	-8.5	-3.4	-9.5	-4.1	-7.6	-0.2	-3.2	3.1	1.2	-7.5	-2.9	-7.7	-1.7	1.8	2.6	-1.9	-5.6	-4.0	-6.7	-4.0
Basal metabolic rate	4.9	27.0	89.5	1.0	1.5	-7.0	-3.2	-8.1	-8.5	-3.4	-9.5	-4.8	-7.8	-0.9	-3.9	2.4	0.5	-7.6	-3.4	-7.9	-2.2	1.0	1.9	-2.4	-5.9	-4.5	-6.9	-4.5
Leg fat-free mass (left)	4.7	24.7	78.7	0.5	1.1	-6.7	-3.1	-7.5	-8.2	-3.2	-8.9	-4.9	-7.4	-1.4	-3.9	1.9	0.2	-7.2	-3.4	-7.5	-2.5	0.6	1.3	-2.5	-5.7	-4.4	-6.6	-4.4
Leg predicted mass (left)	4.6	24.5	78.0	0.5	1.1	-6.6	-3.1	-7.5	-8.1	-3.1	-8.8	-4.9	-7.4	-1.4	-3.9	1.9	0.2	-7.2	-3.5	-7.5	-2.5	0.6	1.3	-2.5	-5.7	-4.4	-6.6	-4.3
Arm predicted mass (right)	4.6	23.5	83.2	1.7	2.3	-6.4	-2.7	-7.6	-8.1	-3.2	-9.1	-4.0	-7.2	-0.2	-3.1	3.1	1.3	-7.1	-2.7	-7.4	-1.7	1.8	2.7	-1.7	-5.3	-3.8	-6.4	-3.8
Age at First Birth	4.3	6.3	10.4	-2.0	-2.0	-2.8	-2.8	-3.0	-2.5	-2.4	-3.0	-1.9	-2.6	-1.5	-2.4	-1.3	-2.0	-3.0	-2.7	-3.1	-3.2	-1.9	-1.9	-2.5	-2.7	-2.7	-2.9	-2.7
Number of self-reported non-cancer illnesses	4.1	7.2	14.7	1.8	1.2	3.3	2.5	3.4	3.8	2.2	3.8	2.9	3.4	1.9	2.7	1.2	1.2	3.4	2.5	3.6	2.1	1.0	1.0	2.2	3.0	2.7	3.3	2.7
Medication: Blood pressure	4.1	7.8	14.0	2.9	2.9	2.7	3.7	1.9	2.3	3.2	2.2	2.8	2.6	2.9	3.4	2.9	2.8	2.6	2.8	2.7	2.4	2.7	2.5	3.0	2.7	3.0	2.7	2.9
Arm fat-free mass (left)	4.1	20.7	73.3	1.6	2.2	-6.0	-2.3	-7.2	-7.6	-2.8	-8.6	-3.6	-6.8	-0.1	-3.0	2.9	1.2	-6.7	-2.5	-7.0	-1.4	1.7	2.5	-1.6	-5.0	-3.6	-6.0	-3.6
Exposure to tobacco smoke outside home	4.0	5.3	9.2	1.7	1.5	2.8	3.0	2.4	2.2	2.1	2.9	2.9	2.9	2.3	2.6	1.1	1.5	2.8	2.3	2.8	1.0	1.4	1.3	2.0	2.6	2.3	2.7	2.4
Eye problems/disorders: Diabetes related eye disease	3.9	4.3	16.7	1.7	2.7	1.6	1.8	1.2	0.7	4.1	0.5	1.9	1.3	2.2	2.5	2.6	2.7	1.1	2.1	1.2	0.9	2.8	2.4	2.6	1.5	2.2	1.3	2.1
Illnesses of siblings	3.9	5.5	8.3	-1.9	-2.5	-2.4	-1.7	-2.3	-1.4	-1.9	-1.9	-2.5	-2.3	-2.3	-2.7	-2.4	-2.6	-2.2	-2.6	-2.4	-1.5	-2.6	-2.3	-2.9	-2.4	-2.8	-2.3	-2.8
Hand grip strength (right)	3.7	10.0	37.6	0.4	1.1	-4.4	-1.4	-4.3	-5.2	-0.0	-6.1	-3.5	-4.9	-1.0	-1.7	1.6	0.6	-4.8	-2.2	-4.7	-0.7	1.0	1.2	-1.2	-3.7	-2.5	-4.4	-2.6
Mean time to correctly identify matches	3.7	7.1	13.2	-2.9	-3.4	-2.2	-2.5	-2.2	-0.2	-3.6	-1.2	-2.2	-2.0	-3.1	-2.8	-3.0	-3.3	-1.9	-2.9	-1.9	-2.8	-3.4	-3.3	-3.1	-2.3	-2.8	-2.1	-2.8
Leg fat percentage (left)	3.7	13.5	39.3	0.4	0.0	4.9	3.6	4.6	5.8	4.0	6.3	4.4	5.2	1.2	2.4	-0.7	0.4	5.2	2.8	5.5	0.7	0.1	-0.1	2.2	4.3	3.4	4.8	3.4
Leg fat percentage (right)	3.6	12.9	38.9	0.0	-0.3	4.7	3.5	4.4	5.9	4.2	6.2	4.2	5.1	0.9	2.2	-1.0	0.1	5.1	2.6	5.3	0.8	-0.2	-0.4	2.0	4.1	3.2	4.7	3.2
Mouth/teeth dental problems: Mouth ulcers	3.6	5.7	8.8	-2.4	-2.3	-2.7	-2.0	-2.5	-0.9	-1.8	-2.4	-2.4	-2.6	-1.9	-2.4	-2.4	-2.2	-2.6	-2.6	-3.0	-2.2	-2.2	-2.2	-2.4	-2.8	-2.6	-2.7	-2.6
Arm predicted mass (left)	3.6	18.4	66.1	1.7	2.3	-5.6	-2.2	-6.7	-7.0	-2.7	-8.1	-3.5	-6.4	0.0	-2.7	3.0	1.4	-6.3	-2.2	-6.5	-1.3	1.8	2.6	-1.3	-4.6	-3.3	-5.6	-3.2
BMI	3.5	20.3	33.9	2.3	3.1	5.5	4.7	4.3	5.7	5.8	5.8	4.4	5.6	2.1	3.8	2.4	3.4	5.7	4.7	5.4	1.2	3.2	2.9	4.6	5.2	5.2	5.6	5.1
Verbal and Numeric Reasoning (VNR)	3.4	8.1	13.7	-2.5	-2.4	-3.3	-2.8	-2.4	-3.7	-3.2	-2.9	-2.7	-3.3	-1.6	-3.0	-1.9	-2.5	-3.2	-3.0	-3.0	-2.7	-2.4	-2.4	-2.9	-3.1	-3.1	-3.2	-3.1
Type 2 Diabetes (T2D) (2012)	3.4	4.0	8.4	0.3	1.1	2.6	1.2	1.9	2.0	2.4	2.9	1.5	2.5	0.7	1.7	0.5	1.5	2.7	2.3	2.7	-1.0	1.6	1.3	2.0	2.4	2.4	2.7	2.4
Vascular/heart problems diagnosed by doctor	3.4	9.2	19.4	-2.0	-2.0	-3.5	-4.0	-3.2	-2.9	-4.4	-3.6	-3.4	-3.6	-2.7	-3.3	-1.9	-2.0	-3.5	-2.7	-3.5	-1.4	-1.9	-1.8	-2.8	-3.3	-3.2	-3.5	-3.1
Lung cancer (father)	3.3	3.9	11.9	-1.6	-2.2	-1.9	-2.1	-2.0	-0.8	-3.5	-1.5	-1.0	-1.7	-1.0	-2.2	-1.6	-2.2	-1.7	-2.0	-1.6	-1.5	-2.2	-2.1	-2.5	-1.8	-2.3	-1.9	-2.2
Intelligence (Savage-Jansen 2018)	3.2	9.8	16.6	-2.2	-2.1	-3.9	-3.1	-3.0	-4.0	-2.6	-3.9	-3.1	-4.0	-1.8	-2.8	-2.1	-2.2	-3.9	-3.2	-4.1	-2.8	-2.1	-2.0	-3.0	-3.6	-3.5	-3.8	-3.4
Medication for cholesterol, blood pressure or diabetes	3.2	5.3	18.2	-1.1	-1.2	-2.6	-3.1	-2.7	-2.1	-4.3	-2.7	-2.6	-2.6	-1.8	-2.5	-1.0	-1.4	-2.6	-1.9	-2.7	-1.3	-1.3	-1.2	-2.0	-2.4	-2.3	-2.5	-2.3
Asthma (self-reported)	3.1	6.2	16.3	2.9	2.1	2.8	1.9	4.0	2.1	0.8	2.6	2.1	2.7	2.2	3.2	1.9	1.9	2.6	2.5	3.2	2.6	1.8	1.4	2.5	2.5	2.7	2.6	2.7
Medication: Atorvastatin	3.1	3.8	9.8	1.3	1.6	2.2	2.1	1.9	3.1	1.4	2.0	1.7	2.3	1.1	2.0	1.8	1.8	2.2	2.2	2.0	1.6	1.8	1.7	1.8	2.2	2.0	2.2	2.0
Blood Red Count	3.0	29.4	57.2	6.8	7.6	3.7	4.6	2.9	2.1	4.5	1.3	5.3	3.0	7.3	6.9	7.3	7.2	3.1	5.6	3.1	4.9	7.4	7.2	6.5	4.3	5.6	3.7	5.5
Heart disease (mother)	3.0	3.6	8.7	1.3	0.9	2.3	2.1	2.1	2.2	1.3	2.6	3.0	2.5	1.6	1.5	0.9	0.9	2.4	1.7	2.6	1.6	0.8	0.8	1.4	2.2	1.8	2.3	1.8
High blood pressure	2.9	8.2	20.2	2.0	2.0	3.2	4.2	2.7	2.2	4.5	3.3	3.4	3.3	2.8	3.2	1.8	2.0	3.2	2.6	3.2	1.3	1.9	1.7	2.6	3.0	3.0	3.2	3.0
Asthma	2.9	5.8	15.9	2.8	2.0	2.7	1.8	4.0	2.2	0.9	2.6	1.8	2.6	1.9	3.1	1.6	1.8	2.6	2.4	3.1	2.5	1.7	1.3	2.4	2.4	2.7	2.5	2.6
Hypertension (Self-reported)	2.9	7.9	19.6	1.7	2.0	3.2	3.8	2.4	2.0	4.4	3.2	3.3	3.2	2.6	3.1	1.8	2.1	3.2	2.6	3.1	1.1	2.0	1.8	2.7	3.0	3.0	3.2	3.0
Long-standing illness, disability or infirmity	2.9	4.5	6.5	2.0	1.9	2.4	2.4	2.5	2.1	1.0	2.1	2.5	2.3	1.9	2.5	1.9	1.9	2.2	2.3	2.5	1.0	1.8	1.8	2.1	2.3	2.2	2.2	2.2
Ovarian Cancer	2.8	3.7	6.6	2.0	1.9	2.0	2.0	2.1	1.2	1.2	1.8	1.5	2.0	1.8	2.4	2.6	1.9	1.9	2.1	1.8	0.9	1.9	1.9	2.0	2.1	2.1	2.0	2.1
Taking other prescription medications	2.8	4.4	12.3	0.7	0.3	2.8	2.3	3.3	3.0	1.1	3.5	1.8	3.0	0.6	1.6	0.4	0.3	2.9	1.8	3.4	-0.2	0.2	0.2	1.3	2.5	2.0	2.7	2.0
Exposure to tobacco smoke at home	2.8	3.2	5.8	1.1	1.0	2.3	0.8	1.4	2.0	0.6	2.4	2.3	2.4	1.3	1.6	1.2	1.3	2.3	2.0	2.0	2.3	1.2	1.4	1.4	2.2	1.7	2.3	1.8
Respiratory disease	2.7	5.9	13.0	2.6	1.7	2.9	2.2	3.6	1.8	1.7	3.0	2.1	2.9	2.0	2.9	1.4	1.5	2.9	2.3	3.2	2.5	1.4	1.1	2.3	2.7	2.6	2.8	2.6
Fluid intelligence score	2.7	5.6	11.8	-2.6	-2.0	-2.7	-2.3	-2.1	-3.4	-1.7	-2.6	-1.9	-2.7	-1.1	-2.5	-1.8	-2.0	-2.8	-2.5	-2.6	-2.2	-1.9	-2.1	-2.3	-2.6	-2.5	-2.7	-2.5
Eye problems/disorders: None of the above	2.7	3.1	5.0	-1.0	-1.4	-2.2	-1.5	-2.0	-1.9	-1.7	-2.2	-1.6	-2.2	-0.9	-1.6	-1.1	-1.5	-2.2	-2.1	-2.2	-0.5	-1.4	-1.3	-1.9	-2.1	-2.0	-2.2	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.7	3.2	7.1	1.1	0.8	2.2	2.3	2.4	1.8	1.2	2.7	2.2	2.3	1.6	1.8	0.3	0.8	2.4	1.6	2.2	0.3	0.7	0.8	1.5	2.1	1.8	2.3	1.8
Alcohol drinker status: Never	2.7	3.2	8.4	-2.5	-2.4	-1.3	-1.5	-1.3	-0.7	-1.3	-0.5	-2.1	-1.2	-2.9	-2.2	-2.2	-2.3	-1.1	-1.8	-1.1	-1.8	-2.3	-2.4	-1.8	-1.4	-1.5	-1.2	-1.6
Illness, injury, bereavement, stress in last 2 years	2.5	3.1	7.2	-1.1	-1.4	-2.0	-2.7	-2.0	-2.1	-1.3	-2.0	-1.9	-2.0	-1.2	-1.8	-1.4	-1.4	-2.0	-1.8	-2.1	-0.1	-1.3	-1.3	-1.6	-2.0	-1.8	-2.0	-1.8
Pain experienced in last month	2.5	4.1	6.6	-1.8	-2.1	-2.1	-1.9	-1.9	-1.4	-0.5	-1.9	-2.5	-2.1	-2.6	-2.5	-2.1	-2.0	-2.1	-2.3	-2.0	-1.0	-2.0	-1.9	-2.2	-2.1	-2.2	-2.2	-2.2
Body mass index (BMI)	2.4	10.4	19.2	1.5	1.9	4.0	3.6	3.4	4.3	3.6	4.4	3.5	4.1	1.6	2.5	1.2	2.1	4.2	3.3	4.1	0.7	2.0	1.8	3.1	3.7	3.6	4.0	3.6
Illnesses of mother	2.4	3.0	9.9	-0.7	0.1	-2.2	-2.0	-2.8	-3.1	0.1	-2.8	-2.3	-2.4	-0.8	-1.5	0.3	0.1	-2.4	-1.2	-2.6	-0.7	0.2	-0.0	-0.6	-2.0	-1.2	-2.2	-1.3
Alcohol intake versus 10 years previously	2.3	3.5	9.1	1.1	1.8	1.9	1.1	2.1	1.3	1.1	1.7	3.0	1.8	2.2	2.0	1.5	2.0	1.9	2.1	2.0	0.5	1.9	1.8	2.2	2.0	2.2	1.9	2.2
Qualifications: A levels/AS levels or equivalent	2.3	5.1	11.8	-1.9	-1.5	-2.7	-2.4	-2.6	-3.4	-1.9	-2.8	-2.2	-2.6	-1.8	-1.9	-1.6	-1.4	-2.7	-2.1	-3.2	-1.9	-1.3	-1.2	-2.0	-2.5	-2.3	-2.6	-2.3
Guilty feelings	2.3	3.5	9.5	-2.3	-2.1	-1.6	-2.0	-1.7	-0.6	-3.1	-1.2	-0.7	-1.3	-1.8	-2.6	-1.6	-2.0	-1.6	-1.8	-1.5	-2.2	-2.0	-2.1	-2.0	-1.8	-1.9	-1.7	-1.9
Ulcerative Colitis (UC)	2.2	4.1	7.6	-1.9	-1.3	-2.3	-2.6	-2.8	-2.0	-2.6	-2.4	-1.7	-2.4	-1.5	-2.0	-1.1	-1.3	-2.4	-1.8	-2.5	-2.0	-1.3	-1.6	-1.7	-2.2	-1.9	-2.3	-2.0
Heel T-Score	2.2	17.4	37.7	2.3	2.8	5.0	3.6	4.7	6.1	2.4	5.0	4.7	5.0	3.1	3.9	2.2	3.3	5.0	4.3	5.0	2.7	3.1	3.2	4.1	4.9	4.6	5.0	4.6
Type 2 Diabetes (T2D) (2018)	2.2	4.1	18.1	0.5	1.1	2.1	3.1	1.9	2.6	4.3	1.9	2.7	2.0	1.6	2.0	0.9	1.4	2.0	1.6	2.2	0.6	1.3	1.2	1.9	1.9	2.1	2.0	2.0
Medication: Simvastatin	2.2	3.2	8.2	0.8	0.8	2.2	2.5	1.7	1.5	2.9	2.4	2.0	2.3	1.2	1.8	0.6	0.9	2.2	1.5	2.1	1.5	0.8	0.8	1.6	1.9	1.9	2.1	1.9
Qualifications: O levels/GCSEs or equivalent	2.2	3.5	7.4	-1.5	-1.3	-2.3	-1.7	-2.0	-2.7	-2.0	-2.2	-1.9	-2.4	-1.5	-1.6	-0.9	-1.3	-2.2	-1.8	-2.4	-1.6	-1.2	-1.0	-1.8	-2.0	-2.0	-2.1	-2.0
Mouth/teeth dental problems: Loose teeth	2.2	2.6	7.6	-1.5	-1.7	-1.5	-2.8	-0.7	-0.9	-2.2	-1.2	-1.9	-1.3	-1.7	-1.5	-1.4	-1.8	-1.4	-1.6	-1.4	-1.0	-1.7	-1.9	-1.7	-1.7	-1.6	-1.5	-1.7
Fed-up feelings	2.1	3.9	8.2	0.9	1.1	2.4	2.7	1.9	2.2	2.6	2.5	2.9	2.6	1.6	1.4	1.5	1.2	2.3	1.8	2.4	-0.1	1.2	1.2	1.6	2.2	1.9	2.3	1.9
Heel bone mineral density (BMD) T-score, automated (left)	2.1	4.7	10.5	1.0	1.2	2.7	1.6	2.5	3.2	2.3	2.9	2.4	2.8	1.6	2.1	0.4	1.5	2.8	2.1	2.6	0.8	1.3	1.1	2.0	2.5	2.3	2.7	2.3
Heart attack	2.1	2.7	9.9	1.0	0.4	2.0	1.6	2.5	3.1	0.7	2.5	1.6	2.1	0.6	1.6	0.3	0.3	2.1	1.3	2.5	0.9	0.2	-0.1	1.1	1.8	1.6	2.0	1.6
Allergy	2.1	4.8	8.8	-2.3	-2.3	-2.2	-1.6	-3.0	-1.1	-1.3	-1.7	-2.2	-2.1	-1.7	-2.7	-2.4	-2.2	-1.9	-2.4	-2.6	-2.2	-2.2	-2.0	-2.4	-2.2	-2.4	-2.0	-2.4
Impedance of arm (right)	2.1	10.0	32.1	-4.2	-5.4	-1.5	-2.0	-0.5	-0.0	-0.6	0.7	-2.5	-1.0	-3.6	-2.7	-4.9	-5.2	-0.9	-3.6	-0.7	-1.9	-5.4	-5.7	-3.9	-2.0	-2.9	-1.4	-2.9
Arm fat percentage (right)	2.1	8.5	26.2	-0.4	-0.3	3.8	3.0	3.4	4.7	4.2	5.1	2.9	4.1	0.2	1.5	-0.9	0.1	4.2	2.0	4.1	0.0	-0.1	-0.4	1.7	3.2	2.7	3.9	2.7
Prospective memory result	2.1	2.6	3.6	1.8	1.9	1.6	1.2	1.1	1.6	0.3	1.1	1.8	1.5	1.5	1.8	1.6	1.9	1.4	1.9	1.3	1.4	1.9	1.9	1.9	1.6	1.8	1.5	1.8
Birth weight	2.1	4.6	11.6	-2.3	-1.1	-2.4	-2.4	-2.8	-1.8	-3.4	-2.8	-2.0	-2.5	-2.2	-2.2	-0.6	-0.9	-2.5	-1.5	-2.9	-2.4	-0.8	-0.5	-1.6	-2.3	-2.0	-2.4	-2.0
Irritability	2.1	3.6	9.7	-3.1	-2.8	-1.4	-0.9	-1.7	-0.4	-0.8	-0.6	-1.2	-1.1	-2.1	-2.2	-2.3	-2.5	-1.1	-2.0	-1.5	-2.4	-2.5	-2.6	-2.2	-1.6	-1.9	-1.3	-1.9
Medication: Omeprazole (e.g. Zanprol)	2.1	2.6	6.5	0.8	0.4	2.0	1.4	2.3	2.1	0.4	2.5	2.4	2.2	1.4	1.4	-0.0	0.5	2.2	1.5	2.2	0.5	0.4	0.5	1.1	1.9	1.5	2.1	1.6
Alzheimer’s Disease (in mother)	2.0	2.4	6.3	-1.9	-1.9	-1.1	-1.5	-0.9	-1.4	-2.1	-0.7	-1.2	-1.1	-1.6	-1.0	-2.0	-1.8	-1.1	-1.4	-1.2	-2.5	-1.8	-1.6	-1.7	-1.3	-1.6	-1.2	-1.5
Severe depression (siblings)	2.0	2.3	3.5	-1.6	-1.4	-1.6	-1.2	-1.6	-1.9	-1.6	-1.2	-1.6	-1.7	-1.1	-1.3	-1.8	-1.4	-1.5	-1.6	-1.6	-1.6	-1.4	-1.3	-1.4	-1.5	-1.4	-1.5	-1.5
Average weekly fortified wine intake	2.0	2.4	4.2	-0.9	-1.1	-1.8	-1.0	-1.6	-2.0	-1.5	-2.0	-0.9	-1.8	-0.5	-1.4	-1.0	-1.3	-2.0	-1.6	-2.0	-0.6	-1.2	-1.2	-1.7	-1.9	-1.9	-1.9	-1.9
Peak expiratory flow (PEF)	2.0	4.7	14.0	3.3	2.8	-2.0	1.1	-1.5	-3.2	1.8	-3.7	-1.0	-2.5	2.4	1.2	3.2	2.0	-2.5	-0.2	-2.5	1.9	2.3	2.3	0.6	-1.5	-0.5	-2.0	-0.5
Illnesses of father: Heart disease	2.0	2.7	9.1	0.5	0.6	1.9	2.3	1.6	3.0	2.0	2.2	1.9	1.9	0.9	1.8	0.3	0.9	2.0	1.5	1.8	1.0	0.7	0.6	1.3	1.8	1.6	1.9	1.6
Arm fat percentage (left)	2.0	8.0	24.0	-0.4	-0.2	3.7	3.0	3.3	4.4	4.1	4.9	2.9	4.0	0.3	1.5	-0.7	0.2	4.1	2.0	4.0	-0.1	0.0	-0.3	1.8	3.2	2.7	3.8	2.7
Schizophrenia (2014)	1.9	4.2	11.3	-2.0	-2.1	-2.0	-2.7	-2.2	-2.0	-3.4	-1.6	-1.5	-2.0	-1.9	-2.3	-1.9	-2.0	-1.8	-1.9	-1.9	-1.5	-2.0	-2.1	-2.0	-2.0	-2.0	-1.9	-2.0
Lung FEV1/FVC ratio	1.9	9.4	13.5	2.1	2.3	3.6	2.7	3.2	3.7	3.2	3.5	3.6	3.6	2.0	2.9	1.9	2.6	3.6	3.3	3.2	2.5	2.5	2.4	3.1	3.5	3.3	3.6	3.4
Hair/balding pattern: Pattern 2	1.9	2.4	5.3	1.1	1.3	1.6	2.1	1.9	2.3	1.0	1.2	1.7	1.5	1.2	1.7	0.9	1.6	1.4	1.6	1.7	1.8	1.6	1.6	1.4	1.6	1.4	1.4	1.5
Medication for pain relief, constipation, heartburn	1.9	3.3	9.5	0.2	0.1	-2.3	-2.2	-2.5	-2.2	-2.3	-2.7	-3.1	-2.5	-1.3	-1.7	-0.5	-0.2	-2.3	-1.2	-2.6	0.6	-0.1	-0.1	-0.9	-1.9	-1.5	-2.1	-1.5
Maternal smoking around birth	1.8	2.6	3.5	1.7	1.8	1.6	0.9	1.2	1.1	1.2	1.2	1.3	1.4	1.9	1.8	1.5	1.8	1.5	1.8	1.7	1.8	1.8	1.7	1.8	1.7	1.8	1.5	1.8
Body fat percentage	1.8	7.2	24.1	-0.7	-0.9	3.4	2.8	3.0	4.6	4.0	4.9	2.9	3.8	0.1	1.1	-1.3	-0.6	3.8	1.5	3.9	-0.1	-0.8	-1.1	1.1	2.8	2.2	3.4	2.1
Back pain experienced in last month	1.8	2.7	5.0	1.5	2.0	1.5	1.2	1.4	1.3	0.5	1.1	1.4	1.4	1.6	2.0	2.2	2.0	1.5	2.0	1.3	1.0	2.0	1.8	2.0	1.6	1.9	1.6	1.9
Tinnitus: Yes, now most or all of the time	1.8	2.1	9.2	0.5	0.1	-2.1	-0.1	-1.2	-3.0	-0.9	-2.6	-0.4	-2.3	0.9	-0.6	0.5	-0.3	-2.2	-1.3	-2.0	-0.4	-0.2	-0.0	-1.0	-1.8	-1.4	-2.1	-1.4
Hand grip strength (left)	1.7	4.5	18.0	1.1	1.6	-2.7	-0.7	-2.8	-3.6	0.1	-4.2	-2.3	-3.2	-0.1	-0.7	1.9	1.2	-3.1	-0.9	-3.0	-0.2	1.5	1.6	-0.1	-2.2	-1.2	-2.7	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.7	4.0	9.7	1.0	1.2	2.6	1.0	2.3	3.1	1.4	2.7	1.9	2.7	1.1	1.9	0.6	1.5	2.7	2.1	2.4	0.9	1.3	1.2	1.9	2.5	2.2	2.6	2.2
Medication: Cholesterol lowering	1.7	2.7	9.6	0.4	0.5	2.0	2.1	2.2	2.0	3.1	2.2	1.5	2.0	0.7	1.6	0.4	0.6	2.0	1.2	2.1	0.8	0.6	0.5	1.1	1.7	1.5	1.9	1.5
Impedance of arm (left)	1.7	7.8	24.9	-3.9	-4.8	-1.4	-1.8	-0.5	-0.0	-0.7	0.5	-2.3	-0.9	-3.1	-2.2	-4.2	-4.5	-0.9	-3.2	-0.6	-1.9	-4.7	-5.0	-3.4	-1.8	-2.6	-1.3	-2.6
Reaction Time	1.6	3.1	5.2	-1.5	-2.0	-1.5	-1.9	-1.8	0.2	-2.3	-0.8	-1.8	-1.4	-2.3	-1.8	-1.8	-2.0	-1.3	-1.7	-1.3	-2.2	-2.1	-1.9	-2.0	-1.4	-1.8	-1.4	-1.8
Number of treatments/medications taken	1.6	2.9	7.4	-0.3	-0.1	2.2	2.3	2.1	2.1	2.7	2.7	2.2	2.4	0.5	1.5	0.4	0.1	2.2	1.2	2.4	-0.8	0.0	-0.1	1.0	1.8	1.5	2.0	1.5
Ever had hysterectomy (womb removed)	1.6	1.8	3.4	-1.8	-1.7	-1.2	-0.4	-0.7	-0.1	-1.4	-0.9	-0.9	-1.2	-1.3	-1.6	-1.8	-1.7	-1.2	-1.6	-0.9	-1.4	-1.7	-1.6	-1.5	-1.4	-1.4	-1.3	-1.4
Hearing difficulty/problems with background noise	1.6	2.6	5.7	-2.3	-1.9	-1.4	-1.2	-1.7	-1.2	-1.4	-0.8	-1.0	-1.2	-1.8	-1.8	-1.4	-1.9	-1.2	-1.7	-1.4	-2.4	-1.9	-1.9	-1.7	-1.5	-1.6	-1.3	-1.6
Medication: Omeprazole	1.6	1.9	5.5	0.7	0.2	1.7	1.6	2.0	1.6	0.0	2.3	2.1	1.9	0.9	1.1	-0.1	0.3	1.9	1.2	1.9	0.4	0.2	0.3	0.8	1.7	1.2	1.8	1.2
Illnesses of siblings: Diabetes	1.6	2.0	3.4	1.0	1.0	1.8	1.6	1.5	1.6	1.2	1.7	1.5	1.8	1.1	1.6	1.1	1.0	1.6	1.3	1.7	0.1	0.9	0.8	1.4	1.6	1.6	1.6	1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.8	4.0	-0.5	-0.8	-1.7	-1.5	-1.4	-0.8	-1.2	-2.0	-1.7	-1.8	-1.5	-0.7	-0.6	-0.9	-1.8	-1.4	-1.7	-0.3	-0.8	-0.8	-1.1	-1.6	-1.4	-1.8	-1.4
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	6.6	-1.8	-1.9	0.5	0.4	0.1	2.6	0.1	1.8	-0.4	0.8	-2.2	-0.9	-2.3	-1.5	1.1	-0.4	0.7	-0.8	-1.6	-1.6	-0.8	0.3	-0.2	0.8	-0.2
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	2.6	1.4	1.3	1.6	1.3	1.0	1.1	0.6	1.5	1.6	1.6	1.1	1.5	1.0	1.3	1.6	1.5	1.2	0.8	1.3	1.3	1.5	1.5	1.5	1.6	1.5
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	5.0	-2.0	-2.0	-1.4	-1.5	-1.7	-1.1	-0.5	-1.0	-1.8	-1.2	-2.1	-2.2	-2.0	-2.0	-1.3	-1.9	-1.4	-2.2	-2.0	-2.0	-1.9	-1.6	-1.7	-1.4	-1.8
Medication: Blood pressure	1.5	2.6	12.6	-0.5	-0.2	1.9	1.7	1.9	2.4	3.6	2.5	1.6	2.0	0.1	1.4	-0.5	0.2	2.1	0.9	2.1	0.1	0.1	-0.3	1.1	1.6	1.5	1.9	1.5
Medication: Aspirin	1.5	2.0	4.4	0.7	0.5	1.8	1.4	1.4	2.0	1.4	1.8	1.7	1.8	0.7	1.3	0.4	0.7	1.7	1.2	2.1	1.9	0.6	0.7	1.1	1.6	1.4	1.6	1.4
Pain type(s) experienced in last month: Hip pain	1.5	1.9	6.1	0.8	1.0	1.5	1.3	0.9	1.5	-0.3	1.5	2.5	1.5	2.2	1.8	0.4	1.1	1.6	1.5	1.2	0.6	1.1	1.1	1.3	1.5	1.5	1.6	1.5
Rheumatoid Arthritis	1.4	1.9	8.1	-2.9	-1.9	-0.6	-1.2	-0.6	-0.6	-0.8	0.2	-1.0	-0.4	-2.0	-1.6	-2.2	-1.6	-0.3	-1.1	-0.4	-2.7	-1.6	-1.8	-1.0	-0.8	-0.7	-0.5	-0.8
Blood Platelet Count	1.4	15.9	28.0	2.1	2.5	4.7	5.0	4.5	4.4	3.9	4.8	5.3	4.7	3.6	4.5	1.6	2.9	4.7	4.0	4.4	2.1	2.7	2.5	3.7	4.5	4.2	4.7	4.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.8	6.8	0.6	0.7	1.6	1.6	0.9	2.6	1.0	1.8	1.6	1.7	0.6	0.8	0.6	0.9	1.7	1.2	1.8	0.1	0.8	0.9	1.2	1.6	1.4	1.6	1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	3.9	-1.5	-1.6	-1.2	-1.2	-0.7	-0.5	-2.0	-1.0	-1.1	-1.2	-1.0	-1.7	-1.3	-1.4	-1.2	-1.5	-1.1	-0.5	-1.4	-1.2	-1.4	-1.3	-1.4	-1.3	-1.4
Leg pain on walking	1.4	1.8	5.4	-1.7	-1.3	-1.3	-1.1	-1.4	-1.0	-0.2	-1.1	-1.4	-1.3	-2.0	-1.2	-1.1	-1.2	-1.3	-1.3	-1.4	-2.3	-1.2	-1.4	-1.0	-1.4	-1.1	-1.3	-1.2
Medication: Aspirin	1.4	1.8	3.9	0.5	0.5	1.8	1.4	1.3	1.8	1.7	1.8	1.6	1.8	0.6	1.3	0.4	0.6	1.7	1.2	2.0	1.4	0.6	0.6	1.1	1.6	1.4	1.6	1.4
Eye problems/disorders: Glaucoma	1.4	1.7	5.1	0.8	1.0	1.6	2.3	1.8	0.9	1.2	1.7	1.0	1.6	0.7	1.0	0.4	0.8	1.6	1.3	1.7	0.0	0.8	0.5	1.3	1.4	1.5	1.6	1.5
Heart attack/myocardial infarction (self-reported)	1.4	1.8	8.1	0.6	0.1	1.6	1.2	2.1	2.8	0.3	2.1	1.3	1.8	0.3	1.3	0.1	0.0	1.8	0.9	2.1	0.5	-0.1	-0.3	0.8	1.4	1.2	1.6	1.2
Alzheimer’s Disease (including proxy)	1.3	1.9	13.5	-1.2	-1.7	-0.9	-1.9	-0.8	-0.9	-3.7	-0.7	-0.7	-0.9	-0.9	-0.7	-1.0	-1.5	-1.0	-0.8	-0.5	-1.4	-1.4	-1.5	-1.6	-1.0	-1.4	-1.0	-1.4
Coronary Artery Disease (CAD)	1.3	1.6	7.2	-1.9	-1.1	-1.1	-0.7	-0.7	0.3	-0.3	-1.5	-1.3	-1.0	-1.0	-0.4	-1.0	-1.1	-1.2	-1.2	-1.1	-2.7	-1.1	-1.4	-1.2	-1.6	-1.3	-1.3	-1.3
Fasting Glucose	1.3	1.6	6.5	1.3	0.7	1.4	1.4	1.7	1.4	1.2	1.7	0.9	1.4	0.8	1.5	0.7	0.8	1.5	1.1	1.0	2.5	0.7	0.8	0.9	1.3	1.1	1.4	1.1
Sensitivity / hurt feelings	1.3	2.3	6.9	-2.3	-2.6	-0.2	-0.2	-0.5	0.7	1.3	1.1	-0.7	0.2	-1.5	-1.8	-2.1	-2.5	0.2	-1.4	0.1	-1.7	-2.6	-2.6	-1.8	-0.5	-1.2	-0.1	-1.2
Hearing difficulty/problems: Yes	1.3	2.0	3.7	-1.2	-1.7	-1.4	-1.9	-0.5	-0.4	-1.6	-0.6	-1.0	-1.3	-1.4	-1.3	-1.9	-1.9	-1.1	-1.7	-1.0	-1.2	-1.9	-1.9	-1.6	-1.3	-1.5	-1.2	-1.5
Relative age of first facial hair	1.3	2.7	9.9	-3.1	-2.8	-0.3	-1.1	-0.5	0.3	0.5	0.8	-1.0	0.2	-2.8	-1.8	-2.6	-2.4	0.1	-1.5	-0.2	-1.8	-2.5	-2.9	-1.4	-0.7	-0.9	-0.2	-1.0
High blood pressure (mother)	1.3	1.8	4.7	1.5	1.2	1.1	2.2	1.2	1.5	1.9	1.0	1.6	1.1	1.2	1.6	0.8	1.2	1.2	1.2	1.1	1.6	1.2	1.3	1.1	1.3	1.1	1.2	1.2
Had other major operations	1.3	1.6	3.6	1.7	1.9	0.8	0.8	0.5	-0.6	1.0	0.3	1.3	0.7	1.5	1.7	1.9	1.8	0.7	1.5	0.3	0.3	1.8	1.7	1.4	1.0	1.2	0.9	1.2
Financial difficulties in last 2 years	1.3	1.7	7.2	0.7	0.9	1.5	1.2	1.5	2.7	0.7	1.5	1.1	1.6	0.7	1.1	0.7	0.9	1.5	1.3	1.6	0.4	0.9	0.7	1.3	1.4	1.4	1.5	1.4
Medication: Ramipril	1.3	1.6	4.1	-0.6	-0.0	1.6	1.7	1.1	1.7	2.0	2.0	1.8	1.7	0.4	1.3	-0.2	0.2	1.7	1.0	1.8	-0.1	0.2	-0.4	1.0	1.3	1.3	1.5	1.3
Weight	1.3	6.5	20.2	0.3	0.6	-3.4	-0.9	-4.3	-4.0	-1.0	-4.5	-2.3	-3.9	-0.7	-2.4	1.0	0.0	-3.7	-1.8	-3.8	-1.5	0.2	0.8	-1.3	-3.0	-2.3	-3.4	-2.3
Father’s age at death	1.3	1.7	4.0	-1.2	-1.1	-1.4	-1.1	-1.0	-1.5	-0.9	-1.1	-2.0	-1.5	-1.6	-1.6	-1.6	-1.1	-1.2	-1.4	-1.1	-1.3	-1.1	-1.2	-1.1	-1.3	-1.2	-1.3	-1.2
Mouth/teeth dental problems: Dentures	1.3	2.2	4.4	1.2	1.9	1.0	1.9	0.8	0.8	1.1	0.3	1.7	0.8	1.6	1.7	1.7	2.0	0.8	1.6	0.8	1.8	2.1	2.0	1.8	1.1	1.5	1.0	1.5
Medication: Amlodipine	1.3	1.9	7.4	0.8	0.3	1.4	1.4	1.9	1.9	1.6	1.8	1.2	1.4	1.2	1.3	-0.2	0.3	1.5	0.9	1.8	2.7	0.3	0.2	1.0	1.3	1.2	1.5	1.2
Illnesses of father: None of the above (group 1)	1.3	1.6	4.3	-0.4	-0.0	-1.6	-1.7	-1.8	-1.9	-0.7	-2.1	-1.2	-1.7	-0.7	-1.3	-0.1	-0.2	-1.8	-1.0	-1.9	-0.9	-0.1	-0.0	-0.7	-1.5	-1.1	-1.7	-1.2
Illnesses of father: High blood pressure	1.3	1.6	5.1	1.4	0.9	1.0	1.5	1.9	0.5	1.9	1.0	1.6	0.8	1.6	1.5	0.5	0.9	1.0	0.9	1.1	2.2	0.9	1.1	1.0	1.1	1.0	1.1	1.0
Schizophrenia (2018)	1.2	2.5	8.0	-1.6	-1.4	-1.7	-2.1	-1.6	-1.7	-2.8	-1.6	-0.5	-1.6	-0.9	-1.7	-1.3	-1.3	-1.6	-1.4	-1.8	-1.1	-1.2	-1.3	-1.5	-1.6	-1.5	-1.6	-1.6
Multivitamins +/- minerals	1.2	1.5	5.2	-1.4	-1.6	-0.6	-1.1	-0.4	-0.5	0.2	0.1	-1.9	-0.6	-2.3	-1.5	-2.0	-1.7	-0.4	-1.2	-0.1	-1.2	-1.7	-2.0	-1.2	-0.8	-0.9	-0.6	-0.9
Medication: Atenolol	1.2	1.5	3.2	1.3	1.1	1.3	1.0	1.5	1.2	0.6	1.2	1.1	1.3	1.2	1.8	1.1	1.0	1.3	1.2	1.2	1.4	1.0	0.9	1.2	1.2	1.2	1.3	1.2
Diabetes (self-reported)	1.2	1.9	8.5	0.1	0.3	1.5	1.8	1.5	2.9	2.6	1.7	1.9	1.3	1.1	1.2	0.1	0.5	1.5	0.9	1.8	0.1	0.4	0.5	0.9	1.4	1.2	1.4	1.2
Pulse wave reflection index	1.2	1.5	7.6	0.5	-0.2	1.4	0.4	1.0	2.8	1.7	2.0	0.4	1.7	0.0	0.0	-0.8	-0.2	1.5	0.7	1.7	2.3	-0.3	-0.4	0.3	1.2	0.7	1.4	0.8
Medication: Paracetamol	1.2	2.0	6.4	-0.6	-0.1	1.7	2.0	1.7	1.4	2.5	2.3	2.2	1.9	0.7	1.1	-0.0	0.2	1.9	1.0	1.6	-0.8	0.1	-0.3	0.8	1.4	1.2	1.7	1.2
Wheeze or whistling in the chest in last year	1.2	2.2	7.0	0.5	0.2	1.9	1.1	2.6	2.3	-0.7	2.4	1.7	2.0	0.8	1.4	0.2	0.2	2.0	1.2	2.2	0.1	0.1	-0.1	1.1	1.6	1.5	1.9	1.4
Alzheimer’s Disease (in father)	1.1	1.2	3.8	1.2	0.6	1.2	0.2	1.0	1.0	-1.9	1.4	1.3	1.3	1.6	1.1	0.7	0.6	1.3	1.2	1.3	0.9	0.5	0.5	0.7	1.3	0.9	1.3	1.0
HbA1C	1.1	1.2	3.8	1.9	1.2	0.9	0.4	0.6	0.6	0.9	1.0	1.1	0.8	1.6	1.3	0.8	0.9	0.9	1.0	0.5	1.7	0.9	1.5	1.2	1.0	1.2	1.0	1.2
Blood Eosinophil Count	1.1	8.4	12.7	3.5	3.4	2.7	2.6	2.9	2.5	1.8	1.9	2.9	2.6	3.3	3.0	3.6	3.2	2.5	3.1	2.5	2.9	3.2	3.0	3.3	2.7	3.1	2.6	3.1
Hypothyroidism (self reported)	1.1	2.6	4.5	-1.6	-1.8	-1.4	-1.8	-1.9	-1.1	-0.8	-1.0	-1.6	-1.2	-1.7	-2.1	-1.8	-1.9	-1.3	-1.8	-1.5	-1.4	-1.8	-1.7	-1.9	-1.5	-1.7	-1.4	-1.7
Qualifications: None of the above	1.1	2.4	6.2	0.8	1.1	1.8	1.8	1.3	2.5	2.1	1.9	1.6	1.9	1.1	1.2	0.8	1.1	1.9	1.6	1.6	1.2	1.1	0.8	1.5	1.7	1.6	1.8	1.6
Emphysema/chronic bronchitis	1.1	1.3	3.1	1.4	1.6	0.9	1.2	0.3	-0.3	0.3	0.1	1.3	0.8	1.1	1.0	1.4	1.6	0.6	1.2	0.9	1.5	1.6	1.8	1.3	1.0	1.1	0.7	1.1
Knee pain experienced in last month	1.1	1.7	4.0	1.0	0.5	1.7	1.8	1.8	1.3	0.3	2.0	1.2	1.8	1.0	1.2	0.4	0.5	1.7	1.2	1.9	1.3	0.4	0.7	0.8	1.7	1.2	1.7	1.2
Qualifications: nursing, teaching	1.1	1.8	6.2	-0.7	-0.8	-1.6	-1.3	-1.1	-2.5	-1.7	-1.5	-1.8	-1.7	-0.4	-0.7	-1.1	-0.9	-1.5	-1.3	-1.6	-0.6	-0.9	-0.8	-1.2	-1.5	-1.3	-1.4	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	4.9	-1.4	-1.3	-0.9	-1.2	-0.4	-0.8	0.0	-0.7	-0.5	-0.9	-1.1	-0.8	-1.1	-1.4	-1.0	-1.4	-0.7	-2.2	-1.3	-1.6	-1.1	-1.2	-1.0	-1.0	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	12.5	0.1	1.1	-1.7	-0.3	-2.3	-3.5	0.3	-2.9	-0.4	-2.0	0.7	-0.1	1.6	1.0	-2.1	-0.4	-2.5	-0.1	1.2	1.3	-0.1	-1.4	-0.8	-1.8	-0.8
Miserableness	1.1	1.9	8.5	-1.8	-1.9	-0.5	-0.3	-1.3	0.3	1.1	0.4	-0.5	-0.2	-1.7	-1.8	-1.2	-1.9	-0.3	-1.4	-0.6	-2.9	-2.0	-2.1	-1.5	-0.9	-1.1	-0.5	-1.2
Fractured/broken bones in last 5 years	1.1	1.4	4.4	-0.4	-0.2	-1.2	-1.1	-1.5	-1.1	-1.5	-1.6	-2.1	-1.4	-1.8	-1.2	0.0	-0.4	-1.5	-0.9	-1.4	-1.0	-0.3	-0.2	-0.6	-1.3	-0.9	-1.4	-0.9
Prostate Cancer	1.0	1.4	4.4	-0.7	-1.7	0.9	-0.3	1.1	1.3	-0.6	2.1	-0.2	1.2	-1.6	-0.8	-2.0	-1.5	1.3	-0.1	1.5	1.4	-1.6	-1.5	-0.7	0.8	-0.0	1.1	0.0
Ulcerative Colitis	1.0	1.5	3.6	-1.4	-0.9	-1.3	-1.6	-1.9	-1.1	0.0	-1.4	-1.2	-1.5	-1.0	-0.9	-1.2	-0.7	-1.4	-1.1	-1.7	-1.5	-0.8	-0.8	-0.8	-1.4	-1.0	-1.4	-1.1
Vitamin and mineral supplements	1.0	1.3	3.7	1.2	1.4	0.8	1.0	0.6	0.5	0.7	0.3	1.6	0.7	1.9	1.4	1.5	1.5	0.7	1.2	0.3	0.9	1.5	1.7	1.3	0.9	1.0	0.8	1.0
Current tobacco smoking	1.0	1.6	3.9	-0.9	-1.8	-0.6	-1.4	0.2	0.8	-1.8	0.0	-1.6	-0.4	-1.8	-1.2	-1.8	-1.9	-0.5	-1.2	-0.1	-0.8	-1.9	-2.0	-1.5	-0.8	-1.2	-0.7	-1.2
Nervous feelings	1.0	1.8	5.8	-2.0	-1.9	-0.9	-0.9	-1.0	0.0	-0.6	-0.4	-1.1	-0.6	-1.4	-1.6	-1.5	-1.7	-0.8	-1.4	-0.8	-2.4	-1.7	-1.5	-1.7	-1.0	-1.5	-0.9	-1.4
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.6	0.8	0.8	1.4	0.9	0.6	1.4	-0.4	1.4	1.6	1.4	1.3	1.2	0.5	0.8	1.4	1.3	1.2	-1.2	0.8	0.9	0.9	1.4	1.1	1.4	1.1
Comparative body size at age 10	1.0	2.8	13.2	-0.8	-1.1	-1.9	-2.0	-1.4	-1.3	-3.6	-1.8	-1.4	-1.9	-1.0	-1.5	-1.2	-1.2	-1.9	-1.4	-1.9	-1.5	-1.2	-0.9	-1.6	-1.8	-1.8	-1.8	-1.8
Pulse wave peak to peak time	1.0	1.2	6.1	0.2	1.1	-1.1	-0.5	-1.1	-2.5	-0.7	-2.0	-0.8	-1.4	0.0	0.3	1.1	1.1	-1.3	-0.0	-1.6	-0.8	1.3	1.4	0.4	-0.8	-0.2	-1.0	-0.2
Smoking status: Current	1.0	1.5	3.6	-0.8	-1.8	-0.4	-1.3	0.4	0.9	-1.8	0.2	-1.6	-0.3	-1.8	-1.2	-1.8	-1.9	-0.3	-1.1	0.2	-0.5	-1.9	-1.9	-1.5	-0.6	-1.1	-0.5	-1.1
Ever taken oral contraceptive pill	1.0	1.1	1.9	-0.5	-1.1	-1.2	-0.7	-1.4	-1.0	-0.4	-1.1	-0.8	-1.2	-1.1	-1.0	-0.7	-1.1	-1.2	-1.2	-1.2	-0.1	-1.1	-0.8	-1.3	-1.1	-1.4	-1.2	-1.3
Impedance of whole body	1.0	5.2	20.0	-3.0	-4.4	0.1	-0.8	0.8	1.6	0.3	2.1	-0.6	0.6	-2.0	-1.1	-3.9	-4.0	0.6	-2.2	1.0	-0.5	-4.2	-4.5	-2.6	-0.5	-1.5	0.1	-1.5
Allergy or Eczema	0.9	2.3	4.5	1.1	1.4	1.6	1.2	1.8	0.9	1.6	1.4	1.7	1.5	0.8	1.5	1.6	1.5	1.5	1.7	1.7	2.1	1.5	1.3	1.7	1.6	1.7	1.6	1.7
Lung FVC	0.9	4.7	18.1	0.3	1.1	-2.7	-0.4	-3.1	-4.2	-0.7	-4.2	-1.2	-3.1	0.2	-0.2	2.1	1.0	-3.2	-1.0	-3.5	-0.9	1.2	1.4	-0.5	-2.3	-1.5	-2.8	-1.5
Supplements: Zinc	0.9	1.0	2.9	-1.4	-1.6	-0.6	-0.2	-0.7	0.2	-0.7	-0.0	-0.7	-0.5	-1.4	-1.2	-1.3	-1.5	-0.4	-1.1	-0.3	-0.5	-1.6	-1.7	-1.1	-0.8	-0.9	-0.5	-0.9
Medication: Co-codamol	0.9	1.0	3.4	-0.5	-0.1	1.4	0.9	1.2	1.2	0.9	1.8	1.3	1.5	-0.1	0.6	-0.2	0.1	1.5	0.8	1.5	-0.1	0.1	-0.1	0.7	1.3	1.0	1.4	1.0
Impedance of leg (right)	0.9	4.3	13.7	-2.2	-3.7	1.1	-0.3	1.6	3.0	0.9	3.0	0.8	1.6	-1.1	-0.3	-3.5	-3.3	1.6	-1.2	1.9	0.6	-3.5	-3.6	-1.8	0.5	-0.7	1.1	-0.6
Trunk fat percentage	0.9	3.6	12.7	-1.2	-1.4	2.2	1.9	1.7	3.3	3.3	3.6	1.8	2.5	-0.5	0.4	-1.6	-1.2	2.5	0.5	2.5	-0.8	-1.4	-1.6	0.3	1.6	1.2	2.2	1.1
Hayfever, allergic rhinitis or eczema	0.9	1.9	3.6	1.3	1.4	1.3	0.9	1.9	0.6	1.1	1.0	1.5	1.2	1.0	1.7	1.6	1.4	1.2	1.4	1.6	1.6	1.4	1.2	1.5	1.4	1.5	1.2	1.5
Medication: Lansoprazole	0.9	1.0	2.9	0.4	0.2	1.1	1.5	0.9	1.5	1.2	1.7	1.5	1.2	1.1	0.9	-0.4	0.1	1.4	0.7	1.2	-0.1	0.0	-0.1	0.7	1.0	1.0	1.3	0.9
Headache pain in last month	0.9	1.6	3.0	-0.4	0.6	1.5	1.6	1.3	1.2	1.7	1.7	1.4	1.6	0.3	0.6	0.4	0.9	1.7	1.3	1.5	-0.5	0.9	0.6	1.4	1.5	1.5	1.6	1.5
Chronic bronchitis/emphysema (mother)	0.9	1.0	4.9	0.3	0.4	1.3	0.7	1.3	2.2	0.1	1.3	1.1	1.3	0.6	0.5	0.3	0.5	1.2	0.9	1.2	1.1	0.5	0.6	0.8	1.1	0.9	1.2	1.0
Shortness of breath walking on level ground	0.9	1.1	3.7	0.5	0.2	1.4	0.5	1.9	1.0	0.1	1.7	0.9	1.5	-0.0	1.0	-0.2	0.3	1.4	1.0	1.9	0.8	0.2	0.4	0.7	1.4	1.0	1.4	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	4.1	-1.3	-1.6	0.0	-0.5	0.8	0.9	0.3	0.8	-0.7	0.3	-1.3	-0.4	-2.0	-1.6	0.2	-0.9	0.3	-1.2	-1.7	-2.0	-0.9	-0.3	-0.5	0.0	-0.5
Number of full sisters	0.9	1.1	5.0	0.9	1.1	0.7	1.1	1.6	0.9	2.2	0.4	0.8	0.7	1.1	1.5	1.4	1.0	0.6	0.8	0.8	-0.2	1.0	0.7	0.9	0.7	0.9	0.7	0.9
Overall health rating	0.9	1.9	4.8	0.7	0.5	1.8	1.7	1.5	1.8	1.1	2.2	1.6	1.8	0.7	1.1	0.5	0.5	1.8	1.2	2.2	-0.4	0.4	0.2	1.0	1.6	1.4	1.8	1.4
Ever had bowel cancer screening	0.9	1.1	4.6	-0.5	-0.7	-1.2	-1.0	-1.0	-1.1	-2.1	-1.3	0.1	-1.2	0.2	-0.9	-0.5	-0.7	-1.3	-1.1	-1.4	-0.1	-0.7	-0.5	-1.1	-1.2	-1.2	-1.3	-1.2
Average weekly beer plus cider intake	0.9	1.3	3.8	1.0	0.3	1.4	0.6	1.5	1.7	0.1	2.0	1.2	1.6	0.8	0.7	0.4	0.3	1.7	1.0	1.5	1.3	0.2	0.5	0.5	1.5	0.9	1.6	1.0
Crohns Disease (2012)	0.8	1.3	3.4	1.8	1.6	0.5	0.7	0.4	0.5	0.3	0.0	0.4	0.1	1.3	1.4	1.6	1.6	0.5	1.2	0.1	1.7	1.6	1.9	1.3	0.8	1.0	0.7	1.0
Impedance of leg (left)	0.8	4.0	12.5	-2.1	-3.5	1.1	-0.3	1.6	2.8	0.6	3.0	1.0	1.6	-0.8	-0.2	-3.4	-3.1	1.6	-1.1	1.9	0.5	-3.4	-3.5	-1.7	0.6	-0.6	1.1	-0.5
Number of incorrect matches in round	0.8	1.3	3.0	1.6	1.4	1.0	1.6	0.4	0.4	-0.4	0.7	1.0	0.9	1.1	1.2	1.5	1.4	1.0	1.3	0.9	0.3	1.3	1.7	1.2	1.2	1.1	1.1	1.2
Number of live births	0.8	1.1	3.1	-1.7	-1.4	-0.7	-1.8	-1.0	-0.6	-0.7	-0.4	-0.4	-0.5	-1.1	-0.9	-1.1	-1.2	-0.7	-1.1	-0.7	-1.0	-1.3	-1.3	-1.1	-0.8	-1.0	-0.7	-1.0
Hair/balding pattern: Pattern 4	0.8	2.1	6.9	0.1	0.2	-2.0	-1.1	-2.0	-2.3	-0.5	-2.6	-0.9	-2.1	-0.2	-1.3	1.1	-0.1	-2.2	-1.2	-2.2	-0.1	-0.0	0.1	-0.8	-1.8	-1.3	-2.0	-1.3
Migraine (self-reported)	0.8	0.9	2.6	1.6	0.8	1.0	1.4	1.3	0.2	-0.0	1.0	0.4	0.9	1.1	0.5	0.8	0.6	1.0	0.9	1.1	1.6	0.6	0.9	0.7	1.1	0.8	1.0	0.8
Chest pain or discomfort	0.8	1.1	4.3	-0.2	-0.4	1.3	1.0	2.1	1.3	-0.3	2.0	1.3	1.4	0.4	0.9	-0.1	-0.4	1.5	0.5	1.9	-0.4	-0.5	-0.6	0.4	1.1	0.8	1.3	0.8
Mother’s age at death	0.8	1.0	3.8	-0.8	-0.6	-1.1	-1.0	-0.9	-0.2	-1.9	-1.1	-1.2	-1.1	-0.5	-1.3	-0.1	-0.8	-1.2	-0.9	-1.0	-1.1	-0.7	-0.6	-1.0	-1.2	-1.1	-1.2	-1.1
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.9	-1.0	-0.2	-1.1	-0.9	-1.5	-1.7	-1.0	-1.6	-0.7	-1.1	-0.9	-1.2	0.4	-0.1	-1.3	-0.7	-1.4	-0.4	-0.0	-0.2	-0.6	-1.1	-0.8	-1.2	-0.9
Medication: Lisinopril	0.8	1.1	2.3	0.3	0.4	1.4	0.7	0.7	0.7	1.1	1.5	1.4	1.5	0.5	0.9	1.0	0.7	1.5	1.0	1.0	0.5	0.7	0.9	0.8	1.4	1.0	1.4	1.1
Myopia	0.8	1.2	3.1	-0.6	-1.3	-1.2	-0.7	-0.1	-1.2	-0.7	-0.7	-1.0	-1.1	-0.8	-1.3	-1.8	-1.4	-0.9	-1.3	-0.7	0.7	-1.4	-1.2	-1.4	-1.1	-1.3	-1.0	-1.3
Neuroticism (Nagel 2018)	0.7	1.7	5.1	-2.1	-2.0	-0.2	0.1	-0.5	1.1	0.5	0.5	0.4	0.1	-1.0	-1.8	-1.9	-2.0	-0.2	-1.2	-0.2	-2.0	-2.0	-2.3	-1.6	-0.8	-1.1	-0.4	-1.2
Bipolar Disorder (2011)	0.7	0.7	2.5	0.0	0.2	-1.0	-0.9	-1.2	-1.5	-0.8	-1.6	-1.1	-1.1	-0.2	-0.4	0.5	0.2	-1.2	-0.4	-1.2	-0.7	0.3	0.0	-0.3	-0.9	-0.6	-1.1	-0.6
Primary Biliary Cirrhosis	0.7	0.9	3.2	0.8	0.7	1.0	0.7	1.1	1.8	-0.4	0.9	1.4	1.0	1.0	1.3	0.2	0.8	1.0	1.1	0.8	-0.2	0.8	0.9	0.9	1.0	0.9	1.0	0.9
Waist Hip Ratio (WHR)	0.7	3.1	11.0	-1.9	-3.0	0.7	-0.8	1.9	2.4	-0.8	2.4	0.1	1.1	-1.6	-0.8	-3.3	-2.7	1.3	-0.9	1.6	-1.0	-2.9	-2.7	-1.5	0.5	-0.6	0.9	-0.5
Medication: Metformin	0.7	1.0	5.1	-1.6	-1.5	0.3	0.4	0.2	2.3	1.5	0.9	0.7	0.4	-0.8	-0.7	-1.4	-1.3	0.4	-0.6	0.6	-0.9	-1.3	-1.4	-0.6	-0.0	-0.2	0.2	-0.2
Qualifications: CSEs or equivalent	0.7	1.0	4.3	0.3	0.3	1.4	1.4	1.0	1.1	2.1	1.4	0.7	1.4	-0.3	0.3	0.2	0.4	1.3	0.8	1.3	-0.2	0.4	0.3	0.6	1.2	0.9	1.2	0.9
Serious illness, injury or assault to yourself	0.7	0.9	6.6	-1.5	-1.1	0.5	-0.0	0.1	0.9	-0.8	1.1	-0.2	0.7	-1.8	-0.4	-0.9	-1.0	0.6	-0.2	0.5	-2.6	-1.0	-1.0	-0.5	0.2	-0.1	0.4	-0.1
Alcohol usually taken with meals	0.7	1.1	3.5	1.9	1.4	-0.2	1.1	0.1	-1.1	1.0	-0.9	0.7	-0.6	1.8	1.0	1.3	1.2	-0.4	0.5	-0.4	1.9	1.3	1.4	0.7	0.1	0.4	-0.2	0.4
Length of working week for main job	0.7	0.8	2.3	1.5	0.8	0.8	0.9	1.1	0.3	-1.2	0.7	0.7	0.8	1.1	1.0	0.7	0.6	0.8	0.8	1.0	0.9	0.6	0.9	0.6	0.9	0.7	0.8	0.7
Tense / ‘highly strung’	0.7	1.1	4.1	0.1	0.8	1.1	1.7	1.0	0.7	2.0	0.9	1.3	1.0	0.6	1.0	0.4	1.0	1.0	1.0	1.1	0.5	1.0	0.9	1.1	1.1	1.1	1.0	1.1
Glaucoma (self-reported)	0.7	0.9	3.3	0.4	0.6	1.0	1.8	1.2	0.7	1.4	1.1	0.5	0.9	0.4	1.0	0.4	0.5	1.1	0.8	1.0	0.2	0.5	0.2	1.0	0.9	1.1	1.1	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.7	-0.7	-0.7	1.1	0.2	0.7	1.7	0.6	1.6	0.4	1.2	-1.3	-0.0	-0.6	-0.5	1.3	0.4	1.6	-0.5	-0.5	-0.6	0.2	0.9	0.6	1.1	0.6
Loneliness, isolation	0.7	1.0	2.9	0.9	1.2	1.0	0.9	0.4	1.2	1.0	0.5	0.7	1.0	0.7	0.7	1.7	1.2	0.8	1.0	0.7	0.9	1.2	1.0	1.1	0.9	1.1	0.8	1.0
Diabetes diagnosed by doctor	0.7	1.2	9.2	-0.7	-0.4	0.9	1.7	0.8	2.3	3.0	1.2	1.6	0.8	0.5	0.5	-0.7	-0.3	0.9	0.1	1.1	-0.8	-0.3	-0.4	0.3	0.6	0.6	0.8	0.5
Eye problems/disorders: Cataract	0.7	0.8	3.8	-1.0	-1.3	0.4	-0.4	0.4	2.0	-0.4	1.1	0.1	0.6	-0.9	-0.7	-1.4	-1.2	0.6	-0.3	0.7	-0.7	-1.3	-1.3	-0.7	0.1	-0.3	0.4	-0.3
Breast cancer (self-reported)	0.7	0.9	4.0	1.1	1.4	-0.3	0.4	-0.5	-0.9	0.8	-0.9	0.6	-0.5	1.4	1.3	2.0	1.3	-0.3	0.6	-0.9	0.6	1.4	1.2	0.8	-0.1	0.4	-0.2	0.3
Depressed Affect (Nagel 2018)	0.6	1.2	4.1	-0.9	-0.9	1.3	1.1	0.7	1.8	1.3	2.0	1.4	1.6	-0.6	-0.5	-0.6	-0.8	1.4	0.2	1.3	-1.3	-0.9	-1.2	-0.1	0.7	0.4	1.2	0.4
Crohns Disease (2017)	0.6	1.3	5.0	1.0	1.7	0.4	0.2	0.2	0.3	-0.8	-0.1	0.8	0.2	1.4	1.3	2.2	1.8	0.5	1.4	-0.1	1.2	1.9	1.9	1.4	0.8	1.1	0.6	1.1
LDL Cholesterol	0.6	0.9	3.0	-0.2	-0.3	1.1	1.2	1.1	0.7	1.6	1.7	1.4	1.3	0.8	0.4	-0.4	-0.1	1.4	0.5	1.3	0.2	-0.2	-0.4	0.3	1.1	0.7	1.2	0.7
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.7	-1.3	-0.8	-0.7	-0.6	-0.4	-0.8	-0.9	-0.7	-0.1	-0.7	-0.7	-1.2	-0.9	-0.8	-0.8	-0.9	-0.6	-1.0	-0.8	-0.8	-0.7	-0.8	-0.8	-0.8	-0.8
Neuroticism score	0.6	1.2	4.7	-2.0	-1.7	-0.4	0.2	-0.6	0.3	0.7	0.2	-0.1	-0.1	-1.1	-1.5	-0.9	-1.5	-0.3	-1.1	-0.3	-2.2	-1.5	-1.7	-1.3	-0.7	-1.0	-0.4	-1.0
Time employed in main current job	0.6	0.7	1.5	-0.1	1.1	0.7	0.5	-0.1	-0.3	-1.1	0.3	1.2	0.6	0.9	0.4	1.0	1.2	0.6	1.1	0.3	-0.7	1.2	1.1	1.1	0.7	1.0	0.7	1.0
Family relationship satisfaction	0.6	0.7	2.7	-1.0	-0.3	-0.9	-0.5	-1.7	-0.2	-0.8	-1.0	-1.5	-0.9	-1.1	-0.9	-0.3	-0.1	-0.9	-0.5	-1.3	-1.4	-0.1	-0.2	-0.4	-0.8	-0.6	-0.8	-0.6
Smoking status: Previous	0.6	0.9	1.7	0.6	0.6	1.1	0.9	0.6	1.3	0.8	1.1	1.1	1.2	0.3	0.6	0.8	0.7	1.2	1.0	0.9	1.2	0.7	0.9	0.8	1.1	0.9	1.2	0.9
Medication: Gliclazide	0.6	0.7	3.1	-0.8	-1.4	0.5	0.3	1.0	1.8	0.2	1.1	0.7	0.6	-0.1	-0.1	-1.2	-1.1	0.6	-0.5	1.1	0.9	-1.1	-0.9	-0.7	0.4	-0.2	0.4	-0.2
Medication: Paracetamol	0.6	1.0	4.1	-1.5	-1.0	0.9	0.7	0.9	0.7	2.0	1.5	1.1	1.1	-0.6	0.2	-1.0	-0.7	1.1	0.1	0.8	-2.0	-0.7	-0.9	-0.1	0.6	0.3	0.9	0.3
Pack years of smoking	0.6	1.0	1.9	0.3	0.7	1.2	-0.1	1.1	1.4	-0.8	1.2	0.8	1.3	0.5	0.6	0.7	0.9	1.2	1.2	1.0	0.4	0.9	1.1	0.9	1.3	1.0	1.2	1.1
HDL Cholesterol	0.5	0.8	2.4	-1.3	-1.2	-0.5	-0.1	-0.7	0.1	-1.0	0.1	-0.0	-0.2	-0.3	-1.1	-1.2	-1.2	-0.3	-0.8	-0.3	-1.6	-1.2	-1.5	-1.1	-0.5	-0.9	-0.4	-0.8
Smoking Status	0.5	1.1	4.4	-0.5	-1.2	1.0	-0.4	1.4	2.1	-1.0	1.8	-0.2	1.2	-1.2	-0.5	-1.3	-1.0	1.2	0.2	1.6	0.7	-1.1	-1.0	-0.3	0.8	0.2	1.0	0.2
Neuroticism	0.5	1.3	4.7	-2.2	-1.9	0.1	0.4	-0.4	1.1	0.5	0.8	0.4	0.4	-1.2	-1.6	-1.4	-1.7	0.2	-0.9	0.2	-1.6	-1.7	-1.9	-1.2	-0.3	-0.8	0.0	-0.8
Angina	0.5	0.6	3.1	-0.8	-0.6	0.9	0.2	0.7	1.8	-0.1	1.2	1.0	1.1	-0.5	0.7	-0.2	-0.4	1.0	0.3	0.9	-0.8	-0.4	-0.4	0.2	0.7	0.4	0.8	0.4
Relative age voice broke	0.5	0.8	3.6	-1.9	-1.3	0.1	0.1	-0.4	0.1	0.7	0.8	-0.5	0.3	-1.8	-1.2	-1.5	-1.0	0.3	-0.6	0.1	-1.1	-1.1	-1.5	-0.4	-0.1	-0.1	0.2	-0.2
Pulse wave Arterial Stiffness index	0.5	0.6	2.2	-0.3	-1.2	-0.2	-0.2	-0.4	0.8	0.1	0.3	-0.2	0.0	-0.3	-1.1	-0.9	-1.4	-0.2	-0.8	0.2	0.3	-1.5	-1.5	-1.2	-0.4	-0.8	-0.3	-0.8
Breastfed as a baby	0.5	0.6	1.4	-0.9	-1.0	-0.5	-0.7	-1.1	0.2	-0.7	-0.2	-0.7	-0.4	-1.2	-1.0	-0.4	-0.9	-0.4	-0.8	-0.5	-1.0	-1.0	-1.0	-0.9	-0.6	-0.8	-0.5	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.3	0.2	1.2	0.6	1.2	-0.3	0.7	0.9	0.0	0.8	0.5	0.1	0.6	1.5	1.3	0.4	0.9	0.1	-1.0	1.3	1.3	1.1	0.6	0.9	0.5	0.9
Angina (self-reported)	0.5	0.6	3.3	-0.6	-0.6	1.0	0.4	0.8	1.8	-0.1	1.3	1.0	1.2	-0.5	0.7	-0.1	-0.4	1.0	0.3	1.0	-0.5	-0.5	-0.4	0.1	0.7	0.4	0.9	0.5
Medication: Seretide 50 evohaler	0.5	0.6	1.8	0.7	0.4	0.9	0.9	1.3	1.3	-0.1	0.9	0.8	0.9	0.2	0.8	0.4	0.4	0.8	0.8	1.3	0.1	0.3	0.3	0.6	0.8	0.8	0.8	0.8
Average weekly red wine intake	0.5	0.7	2.5	-0.4	0.2	-1.1	0.0	-1.3	-1.6	-0.1	-1.5	-1.0	-1.3	-0.0	-0.6	0.6	0.1	-1.1	-0.5	-1.3	-0.4	0.2	0.0	-0.2	-0.9	-0.5	-1.0	-0.6
Mood swings	0.5	1.0	3.7	-0.2	0.3	1.3	1.9	0.4	0.7	1.5	1.4	1.5	1.4	0.4	0.3	0.5	0.4	1.3	0.9	1.0	-0.6	0.4	0.4	0.7	1.1	0.9	1.2	0.9
Osteoarthritis (self-reported)	0.5	0.6	3.0	-0.6	0.1	1.0	0.2	0.7	0.8	-0.7	1.2	0.9	1.2	-0.0	0.3	0.1	0.1	1.0	0.6	0.9	-1.7	0.1	-0.2	0.5	0.7	0.8	0.9	0.7
Hearing aid user	0.5	0.6	4.0	-0.9	-0.1	0.9	0.6	0.9	2.0	0.4	1.2	1.0	0.9	-0.4	0.3	-0.2	0.2	1.0	0.6	0.9	-0.0	0.1	-0.0	0.5	0.7	0.7	0.9	0.7
Bipolar Disorder or Schizophrenia	0.4	1.0	3.9	-1.1	-0.8	-1.0	-1.9	-0.8	-0.9	-2.0	-1.0	-0.3	-1.0	-0.9	-1.1	-0.8	-0.7	-1.0	-0.7	-0.9	-0.8	-0.6	-0.9	-0.7	-1.0	-0.8	-1.0	-0.8
Schizophrenia vs Biploar Disorder	0.4	0.5	1.9	-0.9	-1.1	-0.2	-0.6	-0.8	-0.8	-1.4	0.2	0.4	0.1	-0.4	-1.1	-0.6	-1.1	0.0	-0.7	-0.1	-0.3	-1.1	-1.1	-0.9	-0.4	-0.7	-0.2	-0.7
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	1.1	0.6	0.6	0.9	0.9	0.8	1.1	0.3	0.9	1.0	0.8	0.1	0.7	0.5	0.6	0.8	0.9	1.0	0.0	0.6	0.8	0.7	0.9	0.7	0.8	0.8
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.6	-1.0	0.6	0.3	0.5	-0.6	0.3	1.1	0.1	0.2	0.2	-0.6	0.2	0.6	0.8	0.3	0.5	0.1	-1.6	0.8	0.3	1.0	0.2	0.9	0.4	0.8
Medication for hormone replacement therapy	0.4	0.5	3.0	-1.4	-0.3	-0.4	0.1	-0.6	-1.6	0.4	-0.5	-0.6	-0.5	-1.2	-0.5	-0.3	-0.1	-0.4	-0.4	-0.4	-1.7	-0.2	-0.3	-0.2	-0.5	-0.2	-0.4	-0.3
Diabetes (father)	0.4	0.5	2.1	-0.6	-1.3	0.1	0.2	0.3	1.0	0.2	0.7	0.1	0.3	-0.6	-0.7	-0.9	-1.3	0.3	-0.7	0.4	-0.2	-1.4	-1.4	-1.0	-0.1	-0.6	0.1	-0.5
Pack years adult smoking proportion	0.4	0.6	1.9	0.1	0.4	1.0	-0.2	0.9	1.4	-0.8	1.1	0.5	1.1	0.2	0.3	0.5	0.6	1.0	0.9	0.9	0.1	0.6	0.8	0.6	1.0	0.7	1.0	0.8
Chronic bronchitis/emphysema (father)	0.4	0.4	3.5	-0.8	-0.4	0.7	-0.5	0.4	0.8	-0.3	0.9	-0.5	0.8	-0.7	0.0	-0.1	-0.3	0.7	0.3	0.7	-1.9	-0.3	-0.6	0.1	0.4	0.4	0.6	0.3
Past tobacco smoking	0.4	0.8	4.0	-0.0	0.2	-1.2	-0.3	-0.8	-2.0	-0.1	-1.6	-0.8	-1.3	0.4	-0.1	0.1	0.1	-1.3	-0.7	-1.2	-0.8	0.1	0.1	-0.4	-1.0	-0.7	-1.2	-0.7
Pain all over the body in last month	0.4	0.5	1.4	0.8	0.4	1.0	-0.2	1.0	-0.4	0.3	1.2	0.8	1.0	0.7	0.3	0.3	0.3	0.9	0.6	1.2	-0.1	0.2	0.3	0.5	0.8	0.7	0.9	0.7
Hip circumference	0.4	1.5	7.3	0.2	0.7	-1.6	-0.0	-2.7	-1.3	1.2	-2.1	-1.0	-1.8	-0.3	-1.1	0.8	0.3	-1.7	-0.6	-2.0	-0.8	0.5	0.5	-0.2	-1.4	-0.7	-1.5	-0.8
Worrier / anxious feelings	0.4	0.7	2.8	-0.6	-0.5	-0.9	0.2	-0.8	-1.1	0.9	-1.0	-0.5	-0.9	0.2	-0.8	0.0	-0.7	-1.0	-0.9	-1.0	-1.7	-0.6	-0.7	-0.8	-1.0	-0.9	-1.0	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.1	-0.6	-1.2	0.6	0.1	0.6	1.0	-0.2	1.4	0.4	0.7	-0.6	-0.3	-1.4	-1.1	0.8	-0.2	1.0	-1.1	-1.3	-1.0	-0.6	0.5	-0.1	0.6	-0.1
Health satisfaction	0.4	0.5	1.6	0.4	0.9	0.5	1.3	0.1	0.7	0.3	0.2	0.8	0.3	0.4	0.9	0.8	0.9	0.4	0.7	0.4	-0.7	0.9	1.1	0.9	0.6	0.8	0.5	0.8
Alcohol intake frequency.	0.4	1.0	2.6	0.0	0.4	1.3	0.8	1.4	0.1	1.4	1.6	1.1	1.3	0.0	0.6	0.2	0.5	1.4	0.9	1.4	-0.9	0.3	0.2	0.9	1.2	1.1	1.3	1.1
Had major operations	0.4	0.4	2.2	-1.3	-0.7	-0.1	-1.2	-0.1	-0.4	-0.4	-0.0	-0.3	0.0	-0.9	-0.4	-0.4	-0.6	-0.2	-0.4	-0.5	-1.5	-0.6	-0.9	-0.4	-0.5	-0.3	-0.3	-0.4
Friendships satisfaction	0.4	0.5	2.2	-0.6	-0.1	-0.9	0.5	-1.0	-0.8	0.6	-1.0	-0.5	-0.9	-0.2	-0.1	0.2	-0.2	-0.9	-0.6	-1.0	-1.5	-0.1	-0.3	-0.3	-0.8	-0.5	-0.8	-0.5
Average weekly champagne plus white wine intake	0.4	0.5	1.9	0.6	0.9	0.4	0.7	-0.2	-0.6	1.2	-0.1	1.0	0.4	1.4	0.6	0.6	0.9	0.2	0.6	-0.0	0.3	1.0	1.1	0.7	0.4	0.5	0.3	0.5
Financial situation satisfaction	0.4	0.5	1.0	0.7	0.9	0.5	0.9	0.4	0.8	0.7	0.1	0.6	0.4	0.3	0.9	0.5	1.0	0.4	0.7	0.3	-0.3	1.0	1.0	0.9	0.6	0.8	0.5	0.7
Commuting to job workplace: Public transport	0.4	0.4	1.2	0.1	-0.1	-0.9	-0.6	-0.5	-0.7	-0.5	-1.1	-0.5	-1.0	0.3	-0.6	0.1	-0.3	-1.0	-0.7	-0.9	-0.1	-0.3	-0.3	-0.5	-0.8	-0.7	-0.9	-0.7
Ever smoked	0.4	0.8	2.9	0.0	-0.2	1.2	0.0	1.0	1.7	0.1	1.6	0.5	1.4	-0.5	0.1	-0.5	-0.0	1.3	0.8	1.1	0.8	-0.1	-0.2	0.5	1.0	0.8	1.2	0.8
Risk taking	0.4	0.6	3.5	0.5	-0.5	-0.1	-1.1	-0.2	0.9	-1.9	0.0	-1.0	-0.1	-1.3	-0.7	-0.8	-0.5	-0.1	-0.1	-0.0	1.7	-0.5	-0.4	-0.6	-0.1	-0.5	-0.2	-0.4
Commuting to job workplace: Cycle	0.4	0.5	1.7	-0.6	-0.3	-0.8	-1.0	-1.0	-0.2	-0.2	-0.9	-0.2	-0.7	-0.3	-0.9	0.1	-0.4	-0.8	-0.6	-1.2	-1.3	-0.3	-0.4	-0.6	-0.9	-0.7	-0.8	-0.7
Supplements: Calcium	0.4	0.4	2.2	-0.4	-0.0	-0.7	-0.2	-0.4	-0.8	-0.2	-1.0	-1.5	-0.8	-1.3	-0.2	0.1	0.1	-0.9	-0.4	-0.8	-0.1	0.1	-0.0	-0.1	-0.7	-0.3	-0.8	-0.4
Leg fat mass (left)	0.4	1.5	4.5	0.5	0.5	1.5	1.7	0.8	1.6	2.1	1.8	1.7	1.5	0.5	0.5	0.2	0.5	1.6	1.1	1.6	-0.3	0.4	0.5	1.0	1.4	1.2	1.5	1.2
Depression (Nagel 2018)	0.3	0.5	4.2	-0.3	-0.6	0.5	0.8	0.4	2.1	-0.1	1.0	0.1	0.6	-0.9	-0.3	-0.8	-0.5	0.6	-0.0	1.0	-0.6	-0.6	-0.5	-0.2	0.4	0.1	0.5	0.1
Irritable Bowel Disease (IBD)	0.3	0.8	4.0	-0.4	0.4	-1.0	-1.3	-1.4	-0.9	-2.0	-1.5	-0.5	-1.2	0.1	-0.1	0.8	0.5	-1.1	-0.1	-1.4	-0.3	0.6	0.4	0.0	-0.7	-0.4	-0.9	-0.4
Breast Cancer	0.3	0.7	2.4	0.2	0.1	1.0	1.5	1.1	0.6	0.0	1.4	0.6	1.1	0.4	0.8	0.0	0.2	1.2	0.7	1.0	-0.7	0.1	-0.1	0.7	0.8	0.9	1.2	0.9
Lupus	0.3	0.4	1.6	-1.1	-1.1	0.6	0.1	-0.0	0.3	0.3	1.2	0.7	0.8	-0.1	-0.0	-1.3	-0.7	0.7	-0.2	0.7	0.1	-0.9	-0.9	-0.2	0.5	0.2	0.6	0.2
Triglycerides	0.3	0.5	1.6	0.8	0.8	0.7	0.7	0.4	0.3	1.3	0.5	1.0	0.7	0.7	0.7	1.1	0.7	0.6	0.6	0.6	0.3	0.7	1.0	0.8	0.7	0.8	0.6	0.8
Systolic Blood Pressure	0.3	1.4	13.8	-0.8	0.5	0.2	2.2	0.3	-0.3	3.7	-0.1	1.4	0.1	1.8	1.9	-0.3	0.6	0.1	0.2	0.0	-1.9	0.6	-0.1	0.8	0.1	0.7	0.1	0.6
Chronotype (morning person)	0.3	0.6	2.3	0.7	0.6	0.6	1.2	-0.4	1.5	1.0	0.5	0.3	0.5	1.3	0.3	1.2	0.6	0.6	0.4	0.7	1.4	0.5	0.7	0.6	0.7	0.6	0.6	0.6
Stomach or abdominal pain in last month	0.3	0.4	1.7	0.6	0.4	-0.7	0.0	-0.9	-0.9	-1.3	-0.9	0.1	-0.8	1.1	-0.0	0.6	0.2	-0.7	-0.2	-0.8	0.8	0.3	0.4	-0.1	-0.5	-0.4	-0.6	-0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.3	-0.0	-0.2	-0.8	-0.6	-1.1	-0.6	-0.1	-0.9	-0.6	-0.9	-0.5	-0.7	0.2	-0.3	-0.9	-0.5	-0.6	0.0	-0.2	-0.2	-0.5	-0.7	-0.7	-0.8	-0.6
Medication: Levothyroxine sodium	0.3	0.4	1.5	-0.7	-1.0	-0.0	-0.4	-0.6	0.5	-0.3	0.3	-0.7	0.2	-1.2	-0.8	-1.0	-1.0	-0.0	-0.6	-0.1	-0.6	-1.0	-0.9	-0.7	-0.3	-0.5	-0.1	-0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.2	0.1	-0.3	0.7	0.4	1.5	1.2	0.1	1.0	0.7	0.8	0.3	0.9	0.0	-0.4	0.7	0.3	1.2	-0.0	-0.4	-0.7	0.1	0.5	0.4	0.6	0.4
Pulse rate	0.3	0.5	1.4	0.4	0.4	0.8	1.0	0.7	0.7	0.0	0.7	0.7	0.9	0.7	1.2	0.5	0.5	0.7	0.7	0.8	-0.4	0.4	0.4	0.6	0.8	0.6	0.7	0.7
Noisy workplace	0.3	0.4	2.4	-0.0	-0.1	0.6	0.8	1.1	1.5	0.3	1.0	0.3	0.6	-0.3	0.6	-0.1	-0.1	0.7	0.4	0.7	0.3	-0.1	-0.3	0.3	0.5	0.5	0.7	0.5
Arm fat mass (right)	0.3	1.4	6.9	0.5	0.8	1.3	1.9	0.4	1.5	2.6	1.4	1.3	1.2	0.4	0.5	0.6	0.7	1.4	1.1	1.2	-0.4	0.7	0.7	1.1	1.2	1.2	1.3	1.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.7	-0.4	-0.8	-0.1	0.7	-0.3	0.6	0.4	0.2	-0.3	-0.1	-0.5	-0.3	-1.0	-0.8	0.0	-0.4	-0.3	-1.3	-0.8	-0.7	-0.6	-0.3	-0.4	-0.1	-0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.3	0.0	0.2	0.8	0.1	0.9	0.7	-0.5	1.0	0.8	0.7	1.0	0.6	0.3	0.2	0.8	0.6	1.1	-0.1	0.2	0.1	0.7	0.7	0.8	0.8	0.8
Neck or shoulder pain in last month	0.3	0.5	3.4	-1.3	-0.8	0.3	0.2	0.5	0.5	-1.8	0.8	0.2	0.4	-1.0	-0.6	-1.0	-0.7	0.4	-0.0	0.8	-0.7	-0.7	-0.7	-0.2	0.2	0.1	0.3	0.1
Leg fat mass (right)	0.3	1.2	4.3	0.1	0.1	1.3	1.5	0.7	1.7	2.1	1.8	1.5	1.4	0.2	0.2	-0.2	0.1	1.5	0.8	1.4	-0.4	0.0	0.1	0.7	1.1	1.0	1.3	1.0
Supplements: Vitamin C	0.3	0.4	2.6	0.4	-0.2	-0.4	-0.4	-0.5	-1.3	-1.6	-0.2	-0.9	-0.3	-0.3	-0.6	-0.0	-0.5	-0.3	-0.4	-0.3	1.3	-0.4	-0.4	-0.5	-0.3	-0.5	-0.4	-0.4
Commuting to job workplace: Walk	0.3	0.3	1.4	0.4	0.6	-0.4	-0.2	-0.7	0.1	0.6	-0.8	-0.3	-0.5	-0.2	0.0	0.8	0.7	-0.5	0.2	-0.7	1.2	0.8	1.0	0.4	-0.2	0.0	-0.3	0.1
Arm fat mass (left)	0.3	1.0	5.9	0.3	0.5	1.1	1.7	0.3	1.3	2.4	1.3	1.1	1.1	0.1	0.3	0.4	0.5	1.2	0.8	1.1	-0.5	0.5	0.5	0.9	1.0	1.0	1.1	1.0
Alcohol drinker status: Previous	0.3	0.3	1.1	-0.6	-0.8	0.2	0.4	0.6	0.7	1.0	0.7	0.3	0.3	-0.3	-0.1	-0.3	-0.8	0.3	-0.4	0.6	-1.0	-0.9	-1.0	-0.3	-0.0	-0.1	0.2	-0.1
Major Depression (MDD)	0.2	0.2	0.7	0.5	0.7	-0.1	-0.2	-0.1	-0.8	0.2	-0.6	-0.0	-0.2	0.3	0.4	0.7	0.5	-0.3	0.2	-0.4	-0.7	0.6	0.5	0.3	-0.1	0.1	-0.2	0.1
Neuroticism (2016)	0.2	0.2	1.2	-1.0	-0.6	-0.2	0.2	-0.2	0.3	0.5	0.1	0.1	0.0	-0.5	-0.8	-0.2	-0.6	-0.0	-0.5	0.1	-1.1	-0.6	-0.8	-0.5	-0.3	-0.4	-0.2	-0.4
Tanning	0.2	2.4	5.6	-1.4	-1.3	-1.7	-2.0	-1.4	-1.2	-1.0	-1.8	-1.8	-1.6	-1.6	-1.4	-0.7	-1.3	-1.8	-1.6	-1.5	-2.4	-1.3	-1.2	-1.5	-1.7	-1.7	-1.8	-1.6
Average weekly spirits intake	0.2	0.2	0.9	0.7	0.5	0.4	0.2	0.8	0.5	0.0	0.3	0.3	0.3	0.9	0.8	0.5	0.5	0.3	0.4	0.6	0.1	0.5	0.4	0.4	0.4	0.4	0.4	0.5
Frequency of depressed mood in last 2 weeks	0.2	0.3	2.6	-0.1	-0.1	0.5	1.2	-0.0	1.6	0.8	0.5	0.3	0.5	-0.8	-0.2	0.1	0.0	0.4	0.2	0.5	-0.3	0.0	0.2	0.1	0.4	0.2	0.4	0.3
Systolic blood pressure, automated reading	0.2	0.7	5.9	-0.6	-0.2	0.6	1.3	1.0	0.6	2.4	0.7	1.2	0.6	1.1	1.2	-0.9	-0.1	0.5	0.1	0.7	-0.7	-0.1	-0.4	0.3	0.4	0.5	0.5	0.5
Diabetes (mother)	0.2	0.3	1.0	-0.6	-0.4	0.6	0.8	-0.2	1.0	-0.0	0.9	0.1	0.7	-1.0	-0.2	-0.4	-0.3	0.7	0.1	0.4	-1.0	-0.3	-0.3	-0.0	0.5	0.2	0.6	0.2
Age when periods started (menarche)	0.2	0.5	4.2	-0.9	-0.5	0.4	0.8	0.6	0.3	2.0	0.8	-0.0	0.3	-1.0	-0.3	-1.1	-0.2	0.5	-0.2	0.9	0.1	-0.3	-0.4	0.1	0.5	0.3	0.5	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.6	-0.5	-0.7	0.3	0.3	0.3	1.1	0.7	0.6	-0.4	0.4	-1.3	-0.4	-0.6	-0.6	0.3	-0.2	0.6	-1.1	-0.7	-0.5	-0.3	0.2	-0.1	0.2	-0.1
Had menopause	0.2	0.2	1.3	-1.1	-0.6	-0.2	0.8	-0.6	0.1	0.2	0.1	0.3	-0.1	-0.0	-0.3	-0.3	-0.6	-0.1	-0.4	-0.2	-0.9	-0.6	-1.1	-0.1	-0.4	-0.0	-0.1	-0.1
Happiness	0.2	0.2	0.7	0.2	0.6	-0.2	-0.3	-0.9	-0.6	-0.3	-0.7	-0.3	-0.2	-0.1	0.3	0.8	0.7	-0.4	0.2	-0.6	-0.4	0.7	0.8	0.3	-0.1	0.1	-0.3	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	4.0	-1.0	-0.2	-0.3	0.3	-0.3	-0.3	0.1	-0.4	0.5	-0.2	0.3	0.2	0.3	0.1	-0.3	-0.1	-0.4	-2.0	0.1	0.2	-0.1	-0.2	-0.2	-0.3	-0.2
Birth weight of first child	0.2	0.4	2.4	-0.4	0.4	-0.8	0.2	-1.5	-0.5	-0.8	-1.2	0.1	-1.0	0.4	-0.2	0.1	0.5	-0.9	-0.1	-1.0	-0.7	0.6	0.5	0.1	-0.7	-0.3	-0.7	-0.3
Loud music exposure frequency	0.2	0.2	2.9	-0.6	-0.2	-0.0	-0.6	-0.6	-0.1	-1.7	-0.2	0.2	0.0	-0.5	-0.4	-0.2	-0.2	-0.1	-0.1	-0.2	0.2	-0.2	-0.2	-0.1	-0.1	-0.1	-0.1	-0.1
Number of children fathered	0.2	0.2	1.1	0.5	0.4	-0.3	1.0	0.1	-1.1	0.5	-0.3	-0.2	-0.3	-0.1	0.5	0.5	0.2	-0.3	-0.0	-0.5	-0.5	0.2	-0.0	0.2	-0.3	0.1	-0.2	0.0
Medication: Ibuprofen	0.2	0.2	3.6	-0.9	-0.4	-0.1	-0.1	-0.1	-0.2	-0.4	-0.2	0.6	-0.1	0.1	0.1	-0.0	-0.1	-0.2	-0.1	-0.1	-1.9	-0.1	0.2	-0.2	-0.1	-0.3	-0.2	-0.2
Suffer from ‘nerves’	0.2	0.3	2.9	0.0	-0.1	0.6	0.6	0.5	1.7	0.3	0.7	0.9	0.7	0.7	0.5	0.3	-0.0	0.6	0.4	0.6	-0.4	-0.0	0.0	0.0	0.4	0.2	0.5	0.2
Age at last live birth	0.2	0.3	1.2	-0.4	-0.3	-0.7	-1.0	-1.0	0.0	0.6	-0.9	-0.3	-0.7	-0.1	-0.2	-0.1	-0.1	-0.8	-0.5	-1.1	0.1	-0.1	0.2	-0.6	-0.6	-0.7	-0.7	-0.7
Osteoporosis (self-reported)	0.2	0.2	0.7	-0.4	0.5	0.0	-0.2	-0.3	0.4	-0.2	-0.3	0.7	-0.0	-0.1	0.5	0.9	0.7	-0.1	0.4	-0.3	-0.6	0.7	0.4	0.6	0.0	0.4	-0.0	0.4
Wears glasses or contact lenses	0.2	0.2	1.5	-1.2	-0.6	0.2	0.1	0.6	0.1	-0.2	0.4	0.2	0.2	-0.2	-0.2	-1.0	-0.5	0.2	-0.2	0.4	-0.5	-0.5	-0.9	0.1	-0.1	0.2	0.1	0.1
Number of operations (self-reported)	0.2	0.3	1.7	-0.2	0.3	0.6	-0.9	0.5	0.1	-0.2	0.6	0.6	0.8	-0.0	0.4	0.8	0.3	0.5	0.5	0.0	-1.3	0.3	-0.1	0.5	0.3	0.5	0.5	0.5
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.0	-0.7	-0.4	0.6	-0.4	0.7	1.0	0.8	0.7	0.4	0.7	-0.7	0.1	-0.7	-0.0	0.6	0.3	0.6	-0.5	-0.0	-0.0	0.1	0.5	0.3	0.5	0.3
Age started oral contraceptive pill	0.2	0.3	1.1	-0.5	-0.7	-0.3	0.6	-0.1	1.1	-0.1	0.0	-0.5	-0.2	-0.2	-0.6	-0.8	-0.8	-0.2	-0.6	0.1	0.2	-0.8	-0.9	-0.5	-0.4	-0.4	-0.3	-0.4
Diastolic blood pressure, automated reading	0.2	0.7	2.5	-0.5	-0.6	-0.9	0.3	-0.4	-1.0	1.5	-1.0	-0.3	-1.0	0.7	0.2	-0.7	-0.6	-1.0	-0.9	-0.9	-1.6	-0.6	-0.5	-0.7	-0.9	-0.8	-1.0	-0.8
Basal cell carcinoma (self-reported)	0.2	0.2	3.2	-0.3	0.2	-0.2	-0.2	-0.6	-1.8	-0.1	-0.4	-0.5	-0.3	-0.2	-0.2	0.0	0.3	-0.2	0.1	-0.4	-0.6	0.3	0.3	0.2	-0.1	0.0	-0.2	0.0
Bipolar Disorder (2018)	0.1	0.2	0.5	0.1	0.5	0.5	-0.3	0.7	0.6	0.3	0.4	0.1	0.3	-0.3	0.4	0.2	0.6	0.4	0.6	0.7	0.1	0.5	0.2	0.7	0.4	0.7	0.4	0.6
Worry (Nagel 2018)	0.1	0.2	1.8	-0.5	-0.3	-0.1	1.0	-0.2	0.6	1.3	-0.0	0.5	0.0	0.7	-0.1	-0.3	-0.2	-0.0	-0.3	0.2	-0.2	-0.2	-0.3	-0.3	-0.1	-0.2	-0.1	-0.2
Mean Putamen Volume	0.1	0.2	1.0	0.3	-0.2	0.4	0.1	0.4	0.8	0.1	0.6	0.5	0.5	0.4	0.3	0.3	-0.2	0.4	0.1	0.5	1.0	-0.2	0.0	-0.0	0.4	0.1	0.4	0.1
Townsend deprivation index at recruitment	0.1	0.2	1.9	-0.3	-0.4	0.4	0.2	-0.1	1.4	0.4	0.6	0.1	0.5	-0.4	-0.2	-0.3	-0.2	0.5	0.1	0.4	-0.2	-0.2	-0.2	-0.2	0.4	0.0	0.4	0.1
Supplements: Glucosamine	0.1	0.1	0.8	0.3	0.2	0.4	0.9	0.3	0.2	0.3	0.3	0.1	0.4	-0.2	-0.1	-0.1	0.2	0.3	0.2	0.4	0.5	0.3	0.3	0.2	0.3	0.2	0.3	0.2
Trunk fat mass	0.1	0.5	2.2	-0.7	-0.8	-0.4	0.5	-1.1	0.0	1.5	0.1	0.0	-0.3	-0.7	-1.0	-0.7	-0.9	-0.3	-0.7	-0.3	-1.3	-0.9	-0.8	-0.6	-0.5	-0.5	-0.3	-0.5
Waist circumference	0.1	0.5	2.8	-0.6	-0.6	0.7	0.6	0.2	1.7	0.9	1.3	0.8	0.8	-0.3	-0.4	-0.8	-0.5	0.9	0.2	0.8	-0.7	-0.6	-0.5	-0.0	0.6	0.3	0.8	0.3
Mouth/teeth dental problems	0.1	0.1	1.3	0.0	0.1	0.2	0.1	0.5	-1.1	1.0	0.3	-0.2	0.3	-0.3	-0.1	0.4	0.1	0.3	0.1	0.6	0.1	0.0	-0.1	0.1	0.2	0.2	0.3	0.2
Falls in the last year	0.1	0.2	1.2	-0.0	-0.3	-0.2	-0.5	0.3	0.2	0.4	-0.3	-0.6	-0.2	-1.1	-0.7	-0.2	-0.4	-0.3	-0.3	-0.0	0.2	-0.4	-0.2	-0.4	-0.2	-0.4	-0.3	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.4	0.6	0.3	0.0	0.0	-0.0	-0.5	0.0	0.1	0.4	-0.0	0.4	0.6	-0.1	0.2	0.1	0.2	0.1	0.5	0.2	0.1	0.1	0.1	0.1	0.1	0.1
Depression (self-reported)	0.1	0.2	0.7	0.1	0.5	-0.3	-0.4	0.0	-0.3	0.0	-0.8	0.3	-0.4	0.3	0.2	0.7	0.5	-0.6	0.0	-0.6	-0.0	0.5	0.7	0.2	-0.2	-0.1	-0.5	-0.1
Blood clot in the leg (DVT)	0.1	0.2	1.0	-0.4	-0.3	-0.6	-0.1	-0.2	0.2	0.2	-0.6	-1.0	-0.6	-0.8	-0.1	-0.0	-0.2	-0.5	-0.4	-0.4	-0.1	-0.2	-0.2	-0.3	-0.5	-0.4	-0.5	-0.4
Gout (self-reported)	0.1	0.1	0.7	-0.4	0.1	-0.4	-0.2	-0.5	-0.8	0.5	-0.5	0.2	-0.4	0.1	-0.4	0.3	0.2	-0.4	-0.0	-0.6	-0.4	0.2	0.2	0.1	-0.3	-0.1	-0.3	-0.1
Number of full brothers	0.1	0.2	0.9	-0.2	-0.4	0.5	0.1	0.4	0.1	0.3	0.8	-0.3	0.7	-0.9	-0.4	0.1	-0.4	0.5	-0.1	0.7	-0.6	-0.4	-0.2	-0.1	0.4	0.1	0.4	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.6	-0.6	-0.5	0.4	0.3	0.0	-0.1	0.4	0.6	0.8	0.6	-0.6	-0.7	-0.1	-0.5	0.4	-0.1	0.0	-0.3	-0.5	-0.5	-0.3	0.2	-0.1	0.3	-0.1
Age at first live birth	0.1	0.3	1.1	0.1	0.3	-0.4	-1.1	-0.8	-0.2	-0.6	-0.8	-0.4	-0.5	-0.0	-0.0	0.4	0.5	-0.5	0.0	-0.9	0.5	0.6	0.7	0.0	-0.3	-0.2	-0.4	-0.2
Medication: Allopurinol	0.1	0.1	0.8	0.6	0.3	-0.2	0.2	-0.2	-0.9	0.4	-0.2	0.2	-0.2	0.4	-0.3	0.9	0.2	-0.2	0.0	-0.2	0.5	0.2	0.4	-0.0	-0.0	-0.1	-0.1	-0.1
Whole body fat mass	0.1	0.5	4.9	-0.4	-0.3	0.4	1.0	-0.3	0.9	2.2	0.8	0.7	0.5	-0.3	-0.4	-0.3	-0.3	0.6	0.0	0.5	-0.9	-0.3	-0.3	0.1	0.3	0.3	0.5	0.3
Pulse rate, automated reading	0.1	0.4	1.3	-0.0	0.6	0.4	1.1	0.3	0.5	0.5	-0.0	0.8	0.3	1.0	1.2	0.6	0.8	0.1	0.6	0.2	-0.4	0.8	0.6	0.8	0.4	0.7	0.2	0.6
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.8	0.8	0.2	0.2	0.1	0.5	-0.9	0.1	0.2	-0.4	0.2	-0.3	0.2	0.0	0.0	0.1	0.0	0.5	0.1	0.0	0.2	0.1	0.2	0.1	0.1	0.1
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.8	0.0	-0.4	0.2	-0.2	0.3	0.6	-0.9	0.5	0.5	0.4	-0.2	-0.1	0.0	-0.3	0.4	0.1	0.0	0.8	-0.4	-0.5	-0.2	0.1	-0.0	0.3	-0.0
Mineral and other dietary supplements	0.1	0.1	0.4	0.3	-0.3	0.1	-0.5	0.3	0.6	0.7	0.5	0.3	0.1	0.6	0.5	-0.6	-0.4	0.3	-0.1	0.1	-0.3	-0.4	-0.3	-0.1	0.1	0.0	0.2	0.0
Medication: Bendroflumethiazide	0.1	0.2	1.3	-0.6	-0.1	0.4	0.6	-0.3	0.7	1.1	0.5	0.1	0.4	0.1	0.3	-0.1	0.0	0.4	0.2	0.5	-0.3	0.0	-0.3	0.3	0.3	0.4	0.4	0.4
Ever depressed for a whole week	0.1	0.2	1.1	-0.7	0.1	-0.3	-0.2	-0.8	-0.2	-0.3	-0.4	-0.2	-0.4	-0.6	-0.3	0.2	0.2	-0.3	0.0	-0.7	-1.1	0.3	0.2	0.1	-0.3	-0.0	-0.2	-0.1
Unable to work because of sickness or disability	0.1	0.2	0.7	-0.1	-0.1	-0.4	-0.2	0.4	-0.8	-0.8	-0.3	-0.6	-0.4	-0.6	0.1	-0.3	-0.2	-0.4	-0.3	-0.1	-0.8	-0.2	-0.3	-0.1	-0.4	-0.2	-0.4	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.9	-0.5	-0.2	-0.5	-0.2	-0.2	0.5	0.3	-0.6	-1.0	-0.5	-1.0	-0.0	-0.1	-0.1	-0.5	-0.4	-0.4	-0.6	-0.1	-0.1	-0.1	-0.4	-0.2	-0.4	-0.3
Heart disease (siblings)	0.1	0.1	0.5	-0.3	0.3	0.1	0.2	-0.0	0.3	-0.3	0.0	0.3	0.1	0.2	0.0	0.5	0.2	0.1	0.3	0.0	-0.7	0.3	0.1	0.3	0.1	0.3	0.1	0.3
Hair Pigment	0.0	1.3	4.1	-0.8	-1.2	1.0	-0.4	1.4	0.8	-1.5	2.0	-0.8	1.1	-1.5	-0.4	-2.0	-1.0	1.4	0.1	1.5	0.4	-1.2	-1.2	-0.3	0.9	0.3	1.1	0.3

Hub : Genes

DDX42

Models

Trait associations