[Hub]/) : Traits : BMI : ← →

chr17:65,123,352-66,885,526

Best TWAS P=1.17e-14 · Best GWAS P=4.01e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LINC00674	0.12	0.13	enet	6	0.14	9.9e-12	6.7	6.6	3.9e-11	0.79	0.93	0.07	FALSE
2	GTEx	Adipose Subcutaneous	SH3GL1P3	0.08	0.06	lasso	5	0.04	2.5e-04	6.7	6.8	9.5e-12	0.79	0.06	0.91	FALSE
3	GTEx	Brain Cerebellum	BPTF	0.22	-0.01	lasso	10	-0.01	6.9e-01	7.2	-7.0	2.3e-12	-0.85	0.04	0.48	FALSE
4	GTEx	Brain Cortex	C17orf58	0.34	0.09	lasso	6	0.13	2.4e-04	7.7	7.3	2.4e-13	0.95	0.03	0.95	FALSE
5	GTEx	Cells Transformed fibroblasts	LINC00674	0.30	0.31	enet	10	0.32	1.5e-24	6.7	7.0	3.6e-12	0.86	0.97	0.03	FALSE
6	GTEx	Cells Transformed fibroblasts	LRRC37A16P	0.50	0.46	lasso	8	0.47	1.1e-38	6.7	6.8	9.4e-12	0.83	0.97	0.03	FALSE
7	GTEx	Cells Transformed fibroblasts	SH3GL1P3	0.26	0.31	lasso	7	0.31	1.5e-23	6.7	7.2	4.8e-13	0.90	0.97	0.03	FALSE
8	GTEx	Colon Sigmoid	LINC00674	0.42	0.09	lasso	8	0.12	5.5e-05	7.5	7.0	2.2e-12	0.80	0.10	0.76	FALSE
9	GTEx	Esophagus Mucosa	LRRC37A16P	0.11	0.06	enet	13	0.08	7.5e-06	5.1	-5.8	4.8e-09	-0.67	0.13	0.80	FALSE
10	GTEx	Esophagus Muscularis	LINC00674	0.11	0.04	lasso	6	0.07	7.9e-05	3.9	6.5	6.8e-11	0.77	0.19	0.78	FALSE
11	GTEx	Heart Atrial Appendage	LINC00674	0.14	0.08	lasso	17	0.09	1.1e-04	3.9	5.9	3.6e-09	0.74	0.06	0.86	FALSE
12	GTEx	Nerve Tibial	LINC00674	0.09	0.01	enet	13	0.03	2.2e-03	3.9	5.3	1.2e-07	0.65	0.18	0.30	FALSE
13	GTEx	Nerve Tibial	LRRC37A16P	0.09	0.08	lasso	4	0.06	2.7e-05	6.8	6.9	5.9e-12	0.84	0.11	0.77	FALSE
14	GTEx	Skin Sun Exposed Lower leg	BPTF	0.10	0.01	enet	14	0.03	2.7e-03	7.0	-6.3	2.2e-10	-0.69	0.04	0.81	FALSE
15	GTEx	Spleen	C17orf58	0.30	-0.01	lasso	8	-0.01	4.6e-01	3.8	5.8	7.6e-09	0.80	0.03	0.35	FALSE
16	GTEx	Stomach	RP11-147L13.8	0.23	-0.01	enet	9	0.01	8.1e-02	2.9	5.8	5.0e-09	0.57	0.04	0.18	FALSE
17	YFS	Blood	KPNA2	0.01	0.01	blup	312	0.01	2.8e-04	7.5	-7.4	1.8e-13	-0.85	0.05	0.93	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf58	0.02	0.02	lasso	2	0.01	1.8e-02	7.7	7.7	1.2e-14	1.00	0.00	0.76	TRUE