TWAS hub - MAP3K3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0890	0.0360	1.5e-05	0.074	NA	0.066	NA	0.067	1.2e-06	NA	4.7e-06	NA	3.5e-06
2	GTEx	Adipose Visceral Omentum	0.0970	0.0480	4.5e-03	0.043	NA	0.054	NA	0.053	2.8e-03	NA	9.0e-04	NA	9.8e-04
3	GTEx	Artery Tibial	0.0474	0.0216	6.8e-04	0.066	NA	0.069	NA	0.072	6.8e-06	NA	4.1e-06	NA	2.9e-06
4	GTEx	Breast Mammary Tissue	0.0970	0.0410	3.2e-04	0.111	NA	0.060	NA	0.077	2.5e-06	NA	5.2e-04	NA	8.9e-05
5	GTEx	Breast Mammary Tissue (Male)	0.1163	0.0599	8.1e-03	0.140	NA	-0.003	NA	0.067	4.0e-04	NA	3.8e-01	NA	1.2e-02
6	GTEx	Breast Mammary Tissue (Female)	0.0711	0.0506	7.3e-02	0.011	NA	-0.005	NA	-0.003	1.5e-01	NA	4.8e-01	NA	4.1e-01
7	GTEx	Colon Sigmoid	0.1790	0.0710	1.2e-04	0.085	NA	0.089	NA	0.124	6.4e-04	NA	4.7e-04	NA	3.8e-05
8	GTEx	Esophagus Mucosa	0.0540	0.0290	6.9e-03	0.005	NA	0.019	NA	0.019	1.3e-01	NA	1.8e-02	NA	1.9e-02
9	GTEx	Esophagus Muscularis	0.0740	0.0350	4.0e-04	0.016	NA	0.017	NA	0.017	3.5e-02	NA	3.0e-02	NA	3.3e-02
10	GTEx	Lung	0.0690	0.0291	4.2e-04	0.073	NA	0.028	NA	0.059	2.9e-06	NA	3.1e-03	NA	2.8e-05
11	GTEx	Nerve Tibial	0.0738	0.0299	1.6e-04	0.096	NA	0.052	NA	0.077	2.5e-07	NA	1.4e-04	NA	4.1e-06
12	GTEx	Pancreas	0.0960	0.0490	8.2e-03	0.079	NA	0.036	NA	0.067	3.3e-04	NA	1.2e-02	NA	9.0e-04
13	GTEx	Pituitary	0.1080	0.0560	7.2e-03	0.071	NA	0.007	NA	0.041	7.7e-03	NA	2.1e-01	NA	3.5e-02
14	GTEx	Skin Not Sun Exposed Suprapubic	0.1210	0.0460	1.9e-05	0.132	NA	0.148	NA	0.146	1.1e-07	NA	1.8e-08	NA	2.2e-08
15	GTEx	Skin Sun Exposed Lower leg	0.0760	0.0350	3.3e-04	0.084	NA	0.076	NA	0.076	1.9e-07	NA	7.5e-07	NA	6.8e-07
16	GTEx	Spleen	0.2130	0.0830	5.5e-04	0.142	NA	0.030	NA	0.103	1.7e-04	NA	5.7e-02	NA	1.4e-03
17	NTR	Blood	0.0175	0.0085	6.4e-04	0.013	0.006	0.007	0.007	0.010	4.4e-05	0.004	2.1e-03	0.0024	2.0e-04
18	TCGA	Thyroid Carcinoma	0.0210	0.0160	9.8e-03	0.019	0.014	0.005	NA	0.011	5.0e-03	0.014	9.9e-02	NA	2.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Height	31.2	600.7	767.3	26.1	23.7	27.1	26.9	22.4	26.6	-2.6	20.1	20.0	26.3	26.7	21.8	25.6	26.9	26.9	26.5	-27.7	25.3
Standing height	30.9	306.7	388.1	18.7	16.9	19.3	19.3	15.5	19.1	-0.2	15.3	14.1	18.8	19.1	15.8	18.1	19.3	18.9	19.0	-19.7	18.1
Forced vital capacity (FVC)	24.6	94.8	116.6	10.5	8.8	10.4	10.8	8.5	10.7	1.7	9.2	7.3	10.5	10.8	9.8	9.8	10.8	10.5	10.7	-10.2	10.1
Comparative height size at age 10	24.6	135.2	176.9	12.4	10.9	13.3	12.8	9.8	12.6	-1.3	10.3	9.3	12.4	12.7	10.5	12.1	12.9	12.5	12.5	-13.3	12.0
Forced vital capacity (FVC), Best measure	22.3	81.5	102.0	9.7	7.7	10.0	10.1	7.8	9.9	2.8	8.4	6.2	9.8	10.1	8.8	8.9	10.1	9.7	10.0	-9.8	9.3
Trunk fat-free mass	19.9	114.5	166.4	11.6	9.8	12.5	11.9	8.9	11.8	1.0	8.7	7.6	11.4	11.8	9.7	10.8	12.0	11.8	11.6	-12.9	10.7
Trunk predicted mass	19.8	113.0	163.8	11.5	9.7	12.5	11.8	8.9	11.8	1.1	8.6	7.5	11.3	11.7	9.7	10.7	11.9	11.8	11.5	-12.8	10.6
Sitting height	19.3	137.0	176.9	12.5	12.6	12.8	13.0	9.9	12.9	1.2	10.6	8.0	12.7	12.9	10.0	11.8	12.9	12.8	12.8	-13.3	11.8
Forced expiratory volume in 1-second (FEV1), predicted	17.9	37.1	46.9	6.5	5.3	6.2	6.8	6.1	6.7	0.4	5.3	5.2	6.8	6.8	5.3	6.3	6.7	6.6	6.7	-6.2	6.5
Forced expiratory volume in 1-second (FEV1)	16.9	57.0	72.6	8.3	6.2	7.9	8.4	6.3	8.4	2.3	7.3	5.2	8.3	8.5	7.7	7.5	8.4	8.2	8.5	-7.7	7.9
Whole body fat-free mass	16.8	96.1	139.2	10.7	8.4	11.6	10.8	8.2	10.9	1.1	8.1	7.0	10.3	10.8	9.1	9.9	11.0	10.9	10.7	-11.8	9.8
Whole body water mass	16.7	95.0	139.2	10.6	8.4	11.6	10.8	8.0	10.8	1.2	8.0	6.9	10.3	10.8	9.0	9.8	10.9	10.8	10.6	-11.8	9.8
Forced expiratory volume in 1-second (FEV1), Best measure	14.6	46.5	59.1	7.3	5.5	7.6	7.7	5.5	7.5	3.1	6.9	4.1	7.5	7.7	6.5	6.5	7.6	7.2	7.7	-7.7	7.0
Arm fat-free mass (right)	14.3	73.5	108.2	9.4	7.2	10.3	9.5	6.8	9.6	1.4	7.0	5.9	9.0	9.5	8.0	8.6	9.7	9.6	9.3	-10.4	8.6
Leg fat-free mass (right)	13.6	72.6	104.0	9.3	6.7	10.1	9.4	7.1	9.4	1.1	7.0	6.3	9.0	9.4	8.2	8.5	9.6	9.5	9.3	-10.2	8.6
Leg predicted mass (right)	13.5	71.8	104.0	9.3	6.6	10.1	9.3	7.0	9.4	1.2	7.0	6.2	8.9	9.3	8.2	8.5	9.5	9.4	9.3	-10.2	8.5
Basal metabolic rate	13.3	73.5	110.2	9.3	7.2	10.3	9.5	7.0	9.5	1.3	7.1	6.1	9.0	9.4	8.1	8.6	9.6	9.5	9.3	-10.5	8.6
Arm predicted mass (right)	13.2	67.6	102.0	9.0	6.9	9.9	9.1	6.6	9.2	1.3	6.5	5.6	8.6	9.1	7.7	8.2	9.3	9.2	8.9	-10.1	8.2
Leg fat-free mass (left)	12.3	65.0	95.1	8.8	6.3	9.7	8.9	6.7	8.9	1.2	6.9	5.9	8.4	8.9	7.8	8.1	9.0	8.9	8.8	-9.8	8.1
Leg predicted mass (left)	12.1	64.3	94.1	8.7	6.2	9.6	8.8	6.6	8.8	1.2	6.8	5.9	8.4	8.8	7.8	8.0	9.0	8.9	8.7	-9.7	8.1
Arm fat-free mass (left)	11.8	59.7	93.1	8.4	6.4	9.4	8.6	6.1	8.6	1.5	6.3	5.2	8.1	8.5	7.2	7.7	8.7	8.6	8.4	-9.7	7.7
Hand grip strength (right)	10.8	29.3	38.1	6.2	4.1	6.0	6.0	4.5	6.1	2.8	4.4	3.2	5.6	6.2	5.9	5.2	6.0	6.0	5.9	-5.9	5.6
Arm predicted mass (left)	10.5	53.4	84.3	8.0	6.0	9.0	8.1	5.7	8.2	1.4	5.8	4.9	7.6	8.1	6.8	7.2	8.2	8.2	7.9	-9.2	7.2
Leg fat percentage (left)	9.0	32.5	41.3	-6.2	-6.0	-5.6	-6.4	-5.6	-6.2	0.4	-4.7	-4.2	-6.4	-6.3	-5.2	-5.9	-6.3	-6.1	-6.2	5.9	-5.8
Cholesterol lowering medication	8.8	13.0	16.1	-3.7	-3.2	-3.7	-3.9	-3.9	-3.9	0.7	-2.2	-3.9	-3.9	-3.9	-3.5	-3.9	-3.9	-3.8	-3.9	3.6	-4.0
Leg fat percentage (right)	8.7	31.6	40.7	-6.2	-5.9	-5.4	-6.3	-5.5	-6.2	0.5	-4.3	-4.1	-6.4	-6.3	-5.1	-5.8	-6.3	-6.1	-6.2	5.7	-5.8
Body Mass Index (BMI) (2010)	8.2	11.2	15.1	-3.3	-3.2	-3.7	-3.3	-3.4	-3.2	2.4	-3.9	-3.4	-3.3	-3.1	-3.5	-3.5	-3.3	-3.3	-3.3	3.7	-3.3
Number of self-reported non-cancer illnesses	7.8	13.5	16.2	-3.8	-3.6	-4.0	-4.0	-3.9	-3.8	-0.2	-3.5	-3.1	-4.0	-3.9	-4.0	-3.6	-3.9	-3.7	-3.9	3.9	-3.8
Taking other prescription medications	6.9	10.6	13.6	-3.6	-3.3	-3.1	-3.6	-3.5	-3.5	-1.4	-2.8	-2.5	-3.7	-3.6	-3.0	-3.1	-3.6	-3.5	-3.7	3.0	-3.4
Exposure to tobacco smoke outside home	6.4	8.6	10.8	-3.1	-2.4	-3.3	-3.0	-2.8	-2.9	1.3	-3.2	-2.8	-3.1	-3.0	-2.8	-3.0	-3.0	-2.9	-3.3	3.3	-3.0
Type 2 Diabetes (T2D) (2012)	6.3	7.2	11.0	-3.0	-2.3	-2.7	-3.1	-2.8	-2.9	1.3	-2.1	-2.5	-3.2	-3.3	-1.4	-2.9	-2.8	-2.9	-3.2	2.0	-2.8
Illnesses of mother	6.0	7.4	9.7	2.9	3.0	3.1	2.8	2.4	2.9	2.2	2.5	2.1	2.6	2.9	2.4	2.4	2.9	2.9	2.9	-3.0	2.6
Qualifications: College or University degree	6.0	18.9	22.8	4.6	3.5	4.0	4.6	4.7	4.4	-2.5	4.4	4.7	4.8	4.5	3.9	4.8	4.5	4.3	4.6	-4.1	4.6
Age at First Birth	5.9	8.6	13.2	3.0	3.2	2.7	3.0	2.8	2.9	-1.2	3.1	3.0	3.1	2.9	3.6	3.1	3.0	3.1	3.1	-2.2	3.0
Medication for cholesterol	5.7	8.6	13.3	3.0	3.3	2.6	3.1	3.2	3.0	-2.2	1.4	3.6	3.2	3.0	2.5	3.3	3.1	3.1	2.9	-2.4	3.1
Hair/balding pattern: Pattern 3	5.6	8.3	17.0	2.9	2.5	2.7	2.7	3.1	2.8	-2.1	4.1	3.4	2.7	2.7	2.7	3.1	2.8	2.8	2.9	-2.2	3.0
Arm fat percentage (right)	5.3	20.9	28.7	-5.0	-5.4	-4.2	-5.1	-4.2	-5.1	1.3	-3.4	-3.4	-5.1	-5.1	-4.0	-4.9	-5.1	-5.0	-5.0	4.2	-4.7
BMI	5.1	29.4	37.5	-5.7	-6.1	-4.3	-5.8	-5.8	-5.8	3.2	-4.7	-5.4	-6.0	-5.7	-4.7	-6.1	-5.7	-5.6	-5.9	4.3	-5.8
Cardiovascular Disease	5.1	16.8	35.0	-4.1	-2.6	-3.5	-4.1	-4.4	-4.1	4.5	-2.7	-5.9	-4.0	-4.1	-3.8	-4.7	-4.3	-4.1	-4.0	3.3	-4.5
Hand grip strength (left)	5.1	13.5	18.6	4.3	2.7	4.2	4.1	2.7	4.2	1.9	3.0	1.8	3.8	4.2	4.1	3.6	4.1	4.0	4.1	-4.1	3.7
Blood White Count	4.9	36.4	54.8	-6.1	-4.3	-6.5	-6.2	-6.9	-6.0	3.9	-4.6	-7.4	-6.2	-6.0	-5.7	-6.5	-6.1	-6.0	-6.0	6.6	-6.3
Intelligence (Savage-Jansen 2018)	4.8	14.9	30.0	3.9	5.5	3.5	4.1	4.0	4.0	-0.8	2.3	3.5	4.4	4.1	3.9	4.1	3.9	4.1	4.2	-3.1	4.0
Body fat percentage	4.8	18.9	24.8	-4.8	-5.0	-4.0	-4.9	-4.2	-4.8	0.9	-3.1	-3.0	-5.0	-4.9	-3.9	-4.6	-4.9	-4.8	-4.8	4.2	-4.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.8	5.7	7.0	-2.6	-2.3	-2.5	-2.6	-2.2	-2.6	-0.1	-2.2	-2.4	-2.4	-2.6	-1.8	-2.5	-2.6	-2.5	-2.5	2.5	-2.5
Arm fat percentage (left)	4.8	19.3	27.0	-4.8	-5.2	-4.0	-4.9	-4.1	-4.9	1.3	-3.3	-3.3	-5.0	-4.9	-3.7	-4.7	-4.9	-4.8	-4.8	4.2	-4.5
Heart disease (mother)	4.7	5.7	8.5	-2.7	-2.9	-2.1	-2.5	-2.4	-2.7	-0.4	-2.4	-2.0	-2.4	-2.7	-2.4	-2.5	-2.6	-2.6	-2.7	1.5	-2.5
High cholesterol (Self-reported)	4.7	8.3	13.7	-2.9	-2.0	-2.7	-3.0	-3.1	-2.9	2.0	-1.6	-3.7	-3.0	-3.1	-3.0	-3.2	-3.1	-3.0	-3.1	2.6	-3.2
Medication for cholesterol, blood pressure or diabetes	4.6	7.6	12.2	2.7	1.4	2.6	3.0	3.0	2.7	-2.1	2.3	3.5	3.2	2.8	2.4	3.0	3.0	2.8	2.9	-2.7	2.8
Heart attack	4.5	5.7	10.8	-2.5	-3.3	-2.5	-2.6	-2.7	-2.5	-0.7	-1.7	-1.8	-2.6	-2.6	-1.7	-2.3	-2.5	-2.2	-2.6	2.8	-2.5
Exposure to tobacco smoke at home	4.5	5.1	7.8	-2.4	-1.6	-1.8	-2.5	-2.7	-2.4	-0.0	-1.7	-2.4	-2.7	-2.4	-2.8	-2.3	-2.3	-2.5	-2.5	1.5	-2.4
Peak expiratory flow (PEF)	4.5	10.4	14.5	3.6	3.5	2.7	3.6	1.8	3.7	3.5	3.3	1.1	3.6	3.7	3.8	2.8	3.5	3.4	3.6	-2.4	3.2
Vascular/heart problems diagnosed by doctor	4.5	12.3	18.6	3.6	2.5	3.3	3.7	4.0	3.6	-1.5	2.7	4.3	3.8	3.7	3.4	3.7	3.8	3.6	3.7	-3.6	3.7
Respiratory disease	4.3	9.5	23.0	-3.0	-3.1	-4.2	-3.1	-2.9	-3.0	1.0	-3.1	-2.6	-2.9	-3.1	-2.0	-3.0	-3.1	-2.8	-3.2	4.8	-3.0
Eye problems/disorders: None of the above	4.3	4.9	8.6	2.4	2.9	1.8	2.2	2.4	2.1	-0.9	2.0	2.1	2.3	2.4	2.3	2.2	2.3	2.4	2.5	-1.6	2.4
Medication: Omeprazole (e.g. Zanprol)	4.3	5.2	6.5	-2.5	-2.5	-2.3	-2.5	-2.2	-2.5	-1.3	-2.2	-1.8	-2.5	-2.5	-1.9	-2.2	-2.5	-2.3	-2.3	2.4	-2.4
Tinnitus: Yes, now most or all of the time	4.2	4.8	7.8	2.6	1.1	1.7	2.5	1.9	2.6	0.4	1.1	2.0	2.6	2.6	2.5	2.4	2.6	2.7	2.8	-1.1	2.5
Asthma (self-reported)	4.1	8.1	23.7	-2.5	-2.8	-4.1	-2.8	-2.7	-2.6	-0.2	-3.2	-2.5	-2.5	-2.7	-1.8	-2.5	-2.8	-2.5	-2.8	4.9	-2.8
Fluid intelligence score	4.0	8.2	24.5	2.6	4.9	3.0	2.8	3.0	2.7	-1.1	2.4	2.7	3.0	2.7	2.4	2.8	2.6	2.7	2.8	-3.3	2.7
Verbal and Numeric Reasoning (VNR)	3.9	9.3	23.1	2.9	4.8	2.8	3.2	3.1	3.0	-1.9	1.5	3.2	3.4	3.0	2.5	3.3	3.0	3.1	3.1	-2.9	3.1
Body mass index (BMI)	3.9	16.6	25.4	-4.3	-5.0	-3.4	-4.4	-4.1	-4.4	1.2	-3.5	-3.6	-4.5	-4.4	-3.5	-4.4	-4.4	-4.2	-4.4	3.5	-4.4
Asthma	3.9	7.8	21.9	-2.5	-2.7	-4.0	-2.7	-2.6	-2.5	-0.1	-3.1	-2.5	-2.5	-2.7	-1.6	-2.5	-2.8	-2.5	-2.8	4.7	-2.7
Worry too long after embarrassment	3.9	6.6	13.4	2.3	2.5	2.5	2.2	2.9	2.3	-3.7	1.7	3.5	2.1	2.2	2.0	2.9	2.3	2.6	2.2	-2.7	2.5
Medication for pain relief, constipation, heartburn	3.8	6.6	8.7	2.8	2.0	2.5	2.8	2.4	2.7	-0.2	2.9	2.5	2.8	2.8	2.3	2.6	2.8	2.6	2.9	-3.0	2.5
Medication: Omeprazole	3.8	4.5	8.1	-2.2	-2.8	-2.1	-2.3	-2.0	-2.2	-1.5	-2.4	-1.5	-2.2	-2.2	-1.8	-1.9	-2.2	-2.1	-2.1	2.2	-2.1
Mouth/teeth dental problems: Mouth ulcers	3.8	6.1	8.9	2.6	2.5	2.2	2.5	3.0	2.5	-1.3	2.7	2.9	2.6	2.4	2.0	2.6	2.4	2.5	2.6	-2.2	2.5
High blood pressure	3.7	10.3	16.8	-3.2	-2.0	-3.0	-3.4	-3.7	-3.3	2.0	-2.2	-4.1	-3.5	-3.4	-3.0	-3.5	-3.5	-3.4	-3.4	3.1	-3.4
Number of treatments/medications taken	3.5	6.2	8.8	-2.7	-2.4	-2.0	-2.8	-2.6	-2.6	0.3	-1.5	-2.5	-2.8	-2.9	-2.0	-2.5	-2.9	-2.8	-3.0	2.3	-2.6
Weight	3.5	17.3	30.8	4.4	2.9	5.5	4.5	3.2	4.5	0.9	3.6	3.0	4.2	4.5	3.8	4.0	4.6	4.6	4.4	-5.5	4.1
Qualifications: A levels/AS levels or equivalent	3.5	7.7	10.8	2.9	1.9	2.6	3.0	3.2	2.8	-1.2	3.3	2.6	3.1	2.9	2.6	2.9	3.0	2.8	3.2	-2.5	2.9
Hypertension (Self-reported)	3.5	9.7	16.8	-3.2	-2.1	-2.7	-3.3	-3.6	-3.2	1.9	-1.7	-4.1	-3.4	-3.3	-3.1	-3.4	-3.4	-3.3	-3.2	2.8	-3.3
Illness, injury, bereavement, stress in last 2 years	3.4	4.1	9.1	1.9	3.0	2.0	2.0	1.9	2.0	-0.3	2.7	2.0	1.9	2.0	1.7	2.0	2.0	2.0	2.0	-2.0	2.1
Medication: Simvastatin	3.3	4.9	6.8	-2.3	-2.1	-1.8	-2.5	-2.2	-2.4	1.3	-1.0	-2.5	-2.6	-2.4	-2.2	-2.5	-2.5	-2.3	-2.6	1.5	-2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.3	7.0	9.5	2.7	2.4	3.0	2.9	2.0	2.9	2.7	3.0	1.3	2.7	2.9	2.3	2.3	2.9	2.7	2.8	-3.1	2.5
Heart attack/myocardial infarction (self-reported)	3.3	4.2	9.1	-2.1	-3.0	-2.3	-2.2	-2.2	-2.1	-1.0	-1.3	-1.4	-2.2	-2.2	-1.5	-1.9	-2.1	-1.8	-2.2	2.5	-2.1
Heel bone mineral density (BMD) T-score, automated (left)	3.2	7.3	9.2	-2.9	-1.5	-2.8	-3.0	-2.4	-3.0	0.5	-2.8	-2.5	-3.0	-3.0	-2.6	-2.9	-3.0	-2.9	-2.9	2.6	-2.9
Medication: Paracetamol	3.2	5.3	8.9	-2.3	-2.5	-2.6	-2.3	-1.7	-2.2	1.2	-3.0	-1.9	-2.2	-2.3	-2.1	-2.3	-2.4	-2.4	-2.3	2.9	-2.1
Birth weight	3.2	7.0	13.8	2.9	1.2	3.7	2.8	2.6	2.8	-1.7	1.4	2.4	2.5	2.7	2.7	2.9	2.9	2.6	2.6	-3.3	2.6
Illnesses of father: None of the above (group 1)	3.2	4.0	5.5	2.2	1.8	2.3	2.3	1.9	2.1	0.9	1.6	1.5	2.3	2.2	1.6	1.9	2.2	2.1	2.2	-2.3	2.0
Medication: Blood pressure	3.1	5.5	8.0	-2.3	-1.5	-2.1	-2.6	-2.2	-2.5	1.4	-2.0	-2.7	-2.8	-2.5	-1.5	-2.5	-2.7	-2.6	-2.7	2.4	-2.5
Illnesses of father: Heart disease	3.1	4.3	7.7	-2.1	-2.8	-1.9	-2.4	-2.1	-2.2	0.2	-0.8	-1.8	-2.5	-2.2	-1.4	-2.2	-2.2	-2.1	-2.3	2.1	-2.2
Medication: Atorvastatin	3.1	3.9	6.9	-2.1	-1.7	-1.6	-2.1	-2.2	-2.1	0.3	-1.4	-2.6	-2.1	-2.2	-1.8	-2.1	-2.1	-2.0	-2.2	1.6	-2.1
Lung FVC	3.0	15.1	21.6	4.1	3.2	4.7	4.2	3.3	4.2	2.2	4.6	2.0	4.1	4.2	4.1	3.5	4.1	4.1	4.1	-4.4	3.7
Medication: Cholesterol lowering	3.0	4.7	6.7	-2.2	-1.9	-1.8	-2.4	-2.2	-2.3	1.3	-1.4	-2.6	-2.6	-2.4	-1.9	-2.4	-2.5	-2.2	-2.5	1.8	-2.3
Qualifications: O levels/GCSEs or equivalent	2.9	4.6	5.7	2.3	1.8	2.2	2.3	2.0	2.3	-1.4	2.0	1.8	2.3	2.3	1.9	2.4	2.3	2.2	2.4	-2.0	2.3
Wheeze or whistling in the chest in last year	2.9	5.2	12.2	-2.3	-2.5	-3.0	-2.3	-1.8	-2.4	-1.8	-2.2	-1.4	-2.2	-2.3	-1.4	-2.0	-2.3	-2.1	-2.3	3.5	-2.2
Long-standing illness, disability or infirmity	2.9	4.4	6.6	-2.1	-2.6	-2.3	-2.1	-2.3	-2.1	-0.4	-2.1	-2.1	-2.0	-2.1	-1.6	-2.0	-2.1	-2.1	-2.2	2.5	-2.2
Eye problems/disorders: Glaucoma	2.9	3.4	7.1	-1.8	-2.7	-1.7	-1.9	-2.1	-1.7	0.4	-2.1	-1.5	-2.1	-1.8	-2.1	-1.7	-1.9	-1.9	-1.9	1.2	-1.8
Ulcerative Colitis (UC)	2.8	5.2	7.2	2.3	2.2	2.7	2.2	2.0	2.4	-1.2	2.5	2.5	2.0	2.2	2.5	2.5	2.4	2.2	2.1	-2.4	2.2
Medication: Blood pressure	2.8	5.3	12.7	-2.2	-2.1	-1.8	-2.3	-3.0	-2.2	1.7	-0.6	-3.6	-2.4	-2.2	-2.1	-2.5	-2.2	-2.3	-2.3	1.9	-2.4
Prostate Cancer	2.7	3.7	6.9	-2.0	-2.6	-2.2	-2.1	-1.4	-2.1	-1.8	-1.7	-0.2	-2.1	-2.1	-2.3	-1.6	-2.0	-1.8	-2.0	1.9	-1.7
Heel T-Score	2.7	21.2	25.1	-5.0	-4.1	-4.6	-4.9	-4.5	-5.0	-0.4	-4.5	-4.6	-5.0	-4.9	-4.9	-4.8	-4.8	-4.9	-5.0	4.0	-4.9
Fed-up feelings	2.7	4.9	7.2	-2.5	-1.5	-1.6	-2.4	-2.2	-2.4	0.8	-2.1	-2.5	-2.5	-2.6	-1.9	-2.5	-2.5	-2.3	-2.7	1.4	-2.5
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.3	8.0	-2.7	-1.8	-2.6	-2.8	-2.2	-2.8	-0.1	-2.2	-2.2	-2.8	-2.8	-2.4	-2.7	-2.7	-2.7	-2.6	2.6	-2.7
Knee pain experienced in last month	2.7	4.2	8.9	-2.1	-1.0	-2.6	-2.1	-2.1	-2.0	-0.8	-2.6	-1.5	-2.0	-2.0	-2.1	-1.7	-2.0	-2.0	-2.3	3.0	-1.9
Ever had stillbirth, spontaneous miscarriage or termination	2.7	2.9	4.8	2.0	1.1	0.9	2.0	2.1	2.0	-0.4	1.0	1.7	2.1	2.0	1.5	1.9	1.9	2.2	1.8	-0.3	1.8
Average weekly fortified wine intake	2.6	3.1	6.4	1.8	2.5	1.2	1.9	1.9	1.9	-0.8	0.8	1.8	2.0	1.9	0.7	2.0	1.9	1.9	2.0	-1.2	2.0
Medication: Ramipril	2.6	3.3	4.5	-1.8	-2.0	-1.6	-2.0	-1.6	-2.0	0.2	-1.1	-1.9	-2.1	-2.0	-1.6	-1.9	-2.0	-2.1	-2.1	1.8	-2.0
Pulse wave reflection index	2.6	3.2	5.7	-2.1	-0.4	-1.5	-2.0	-1.4	-2.0	1.2	-1.9	-0.9	-2.0	-2.0	-2.4	-2.0	-1.9	-2.0	-2.1	1.1	-1.8
Shortness of breath walking on level ground	2.6	3.1	5.3	-1.7	-2.2	-2.2	-1.7	-1.6	-1.7	0.6	-2.3	-1.1	-1.8	-1.6	-1.9	-1.6	-1.6	-1.4	-1.6	2.3	-1.5
Pulse wave peak to peak time	2.5	2.9	4.9	1.9	0.6	1.6	1.9	1.7	1.9	-0.3	1.3	0.4	2.0	2.0	1.9	1.8	1.9	2.2	2.2	-1.5	1.7
Type 2 Diabetes (T2D) (2018)	2.4	4.5	7.8	-1.8	-1.9	-1.9	-2.1	-2.0	-1.9	2.7	-2.8	-2.6	-2.2	-2.1	-1.6	-2.3	-2.2	-1.9	-2.1	1.7	-2.1
Trunk fat percentage	2.4	9.7	15.7	-3.4	-4.0	-2.8	-3.6	-3.0	-3.5	0.9	-2.0	-1.9	-3.6	-3.5	-2.5	-3.3	-3.5	-3.4	-3.4	3.1	-3.1
Chest pain or discomfort	2.4	3.5	6.4	-1.9	-2.2	-2.5	-1.9	-1.8	-1.9	-1.5	-2.1	-0.9	-1.8	-1.8	-2.0	-1.6	-1.8	-1.7	-1.6	2.5	-1.6
Hair/balding pattern: Pattern 4	2.3	5.5	7.7	2.4	2.2	2.6	2.7	2.0	2.6	1.2	1.0	1.9	2.6	2.7	2.2	2.3	2.7	2.6	2.6	-2.8	2.4
High blood pressure (siblings)	2.3	3.3	9.7	-1.6	-1.6	-1.2	-1.6	-2.6	-1.6	3.1	-0.2	-2.8	-1.6	-1.6	-1.1	-2.1	-1.6	-1.8	-1.5	1.6	-1.9
Medication: Aspirin	2.3	3.1	5.2	-1.9	-0.6	-1.4	-1.9	-1.7	-1.8	-0.1	-1.7	-1.8	-2.1	-1.9	-2.3	-1.8	-1.9	-1.7	-2.1	1.4	-1.9
Medication: Aspirin	2.3	3.0	4.8	-1.9	-0.7	-1.3	-1.9	-1.6	-1.9	0.2	-1.6	-1.8	-2.0	-1.9	-2.2	-1.8	-1.9	-1.7	-2.1	1.4	-1.9
Fasting Glucose	2.2	2.6	5.0	-1.6	-0.5	-2.2	-1.7	-1.6	-1.6	-0.5	-0.5	-1.7	-1.6	-1.6	-1.8	-1.5	-1.7	-1.7	-1.7	2.2	-1.6
Lung FEV1/FVC ratio	2.2	11.0	21.8	-3.5	-4.7	-2.8	-3.5	-3.3	-3.5	1.5	-2.0	-3.1	-3.5	-3.6	-3.6	-3.7	-3.5	-3.6	-3.3	1.9	-3.5
Tinnitus: Yes, but not now, but have in the past	2.2	2.4	8.5	-1.8	-2.9	-0.6	-1.6	-0.9	-1.8	-1.2	-0.9	-0.7	-1.6	-1.8	-1.8	-1.4	-1.6	-1.6	-1.7	0.1	-1.4
Illnesses of siblings	2.2	3.1	5.7	1.7	2.0	1.5	1.8	2.1	1.8	-1.2	0.4	2.4	1.8	1.8	1.0	2.0	1.8	1.8	1.7	-1.9	2.0
Lung cancer (father)	2.2	2.6	7.1	1.4	2.2	1.4	1.5	1.4	1.4	-2.7	0.3	2.2	1.5	1.4	1.0	1.8	1.6	1.6	1.2	-1.2	1.6
Ovarian Cancer	2.1	2.7	5.4	-1.6	-0.9	-1.7	-1.6	-2.0	-1.7	1.4	-1.0	-2.3	-1.4	-1.6	-1.0	-1.9	-1.6	-1.8	-1.4	2.1	-1.7
Medication: Co-codamol	2.1	2.4	4.7	-1.8	-2.2	-1.4	-1.7	-1.0	-1.8	0.0	-0.6	-1.1	-1.6	-1.8	-1.5	-1.6	-1.8	-1.9	-1.7	1.3	-1.7
Pain experienced in last month	2.1	3.5	5.4	1.9	1.2	1.9	1.9	2.1	1.9	-0.3	1.2	2.3	1.8	1.9	1.6	1.9	1.9	2.0	2.1	-2.3	2.1
Financial difficulties in last 2 years	2.0	2.7	5.7	-1.5	-1.9	-2.0	-1.5	-1.6	-1.5	0.2	-2.4	-1.2	-1.4	-1.5	-2.0	-1.5	-1.5	-1.5	-1.6	1.9	-1.6
Average weekly beer plus cider intake	2.0	2.9	4.8	-1.9	-0.8	-1.7	-1.8	-1.7	-1.9	-0.7	-1.7	-1.4	-1.8	-1.9	-2.2	-1.8	-1.9	-1.7	-2.0	1.5	-1.8
Eye problems/disorders: Diabetes related eye disease	1.9	2.0	22.6	-0.6	-0.4	-0.8	-0.6	-1.3	-0.5	4.8	-0.7	-1.9	-0.7	-0.6	-0.2	-1.3	-0.8	-0.6	-0.7	1.3	-0.9
Severe depression (siblings)	1.9	2.1	4.3	1.4	1.3	0.9	1.6	1.8	1.4	-0.5	2.1	1.5	1.8	1.4	0.7	1.6	1.4	1.7	1.6	-0.7	1.5
Diabetes (self-reported)	1.9	2.9	8.7	-1.5	-0.4	-1.4	-1.9	-1.6	-1.6	1.1	-3.0	-1.8	-2.0	-1.8	-1.4	-1.8	-1.9	-1.6	-2.0	1.1	-1.7
Medication: Lansoprazole	1.9	2.2	3.3	-1.8	-1.7	-1.3	-1.6	-1.5	-1.7	1.1	-0.5	-1.4	-1.6	-1.6	-1.1	-1.7	-1.6	-1.5	-1.6	1.3	-1.5
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	6.2	-1.6	-2.5	-1.0	-1.7	-1.1	-1.7	-0.5	-1.7	-1.0	-1.7	-1.7	-1.0	-1.5	-1.7	-1.5	-1.9	1.2	-1.5
Illnesses of siblings: Diabetes	1.9	2.4	3.5	-1.5	-1.7	-1.8	-1.6	-1.5	-1.6	-0.0	-1.9	-1.4	-1.4	-1.6	-1.1	-1.5	-1.6	-1.6	-1.4	1.9	-1.6
Fractured/broken bones in last 5 years	1.9	2.4	5.0	1.7	0.2	1.7	1.6	1.6	1.7	-0.0	1.3	1.5	1.7	1.5	2.2	1.6	1.6	1.4	1.7	-1.6	1.6
Alzheimer’s Disease (in father)	1.8	2.0	3.3	-1.4	-0.9	-1.8	-1.4	-1.4	-1.4	-1.7	-1.4	-0.5	-1.2	-1.4	-1.7	-1.1	-1.3	-1.4	-1.4	1.8	-1.4
Bipolar Disorder (2011)	1.8	1.7	3.6	1.6	0.9	1.4	1.5	1.1	1.5	0.4	1.9	1.0	1.5	1.5	1.7	1.4	1.5	0.0	1.4	0.0	1.4
Blood Platelet Count	1.8	20.8	25.2	-4.8	-5.0	-4.8	-4.8	-4.4	-4.8	1.2	-3.3	-4.7	-4.6	-4.9	-4.2	-4.8	-5.0	-5.0	-4.8	4.8	-4.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	3.4	-1.7	-1.3	-1.3	-1.7	-1.5	-1.7	0.3	-1.4	-1.5	-1.7	-1.8	-1.8	-1.7	-1.6	-1.7	-1.7	1.1	-1.7
Qualifications: None of the above	1.8	3.7	5.2	-2.1	-2.1	-1.5	-2.1	-2.0	-1.9	1.7	-1.8	-1.8	-2.3	-2.0	-2.0	-2.1	-1.9	-1.7	-2.2	1.5	-2.0
Medication: Amlodipine	1.8	2.6	4.7	-1.6	-0.4	-1.8	-1.7	-1.5	-1.7	0.0	-1.0	-1.8	-1.5	-1.7	-2.2	-1.7	-1.8	-1.7	-1.8	1.8	-1.7
Overall health rating	1.8	3.9	5.6	-2.1	-2.1	-1.6	-2.1	-2.1	-2.1	-0.4	-2.3	-1.9	-2.1	-2.1	-1.3	-2.0	-2.1	-2.0	-2.4	1.8	-2.1
Supplements: Fish oil (including cod liver oil)	1.8	2.3	4.6	1.4	1.3	2.1	1.6	1.4	1.5	-1.1	1.4	0.9	1.5	1.5	1.3	1.6	1.6	1.5	1.5	-2.1	1.4
Pain type(s) experienced in last month: Hip pain	1.7	2.2	3.4	-1.5	-1.4	-1.6	-1.6	-1.5	-1.5	-0.3	-0.9	-1.5	-1.6	-1.5	-1.8	-1.4	-1.4	-1.6	-1.4	1.5	-1.6
Medication: Paracetamol	1.7	2.6	5.6	-1.5	-2.3	-1.8	-1.6	-0.9	-1.5	0.4	-2.4	-1.0	-1.5	-1.6	-1.3	-1.4	-1.7	-1.6	-1.7	2.3	-1.3
Qualifications: CSEs or equivalent	1.6	2.2	3.7	-1.4	-1.8	-1.2	-1.5	-1.2	-1.4	1.1	-1.9	-1.1	-1.5	-1.6	-1.2	-1.5	-1.6	-1.6	-1.5	1.4	-1.5
Chronic bronchitis/emphysema (mother)	1.6	1.8	5.0	-1.2	-0.3	-1.5	-1.3	-1.1	-1.3	0.1	-2.2	-1.0	-1.3	-1.3	-1.9	-1.2	-1.4	-1.3	-1.3	1.8	-1.3
Average weekly red wine intake	1.6	2.3	5.5	1.5	1.2	1.9	1.4	1.3	1.4	2.0	2.3	1.2	1.2	1.4	1.3	1.1	1.4	1.2	1.4	-2.1	1.3
Depressed Affect (Nagel 2018)	1.5	3.1	4.6	-2.0	-2.1	-1.2	-2.0	-1.5	-2.0	-0.4	-1.7	-0.9	-2.0	-2.1	-2.0	-1.8	-2.0	-2.0	-2.0	1.2	-1.8
Hair/balding pattern: Pattern 2	1.5	1.9	4.3	-1.2	-1.0	-1.5	-1.4	-1.2	-1.2	0.4	-2.1	-1.7	-1.4	-1.3	-1.5	-1.3	-1.3	-1.2	-1.6	1.5	-1.3
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	3.1	-1.5	-1.4	-1.2	-1.5	-1.6	-1.4	-0.3	-0.6	-1.8	-1.5	-1.5	-1.4	-1.4	-1.4	-1.4	-1.2	1.1	-1.5
Glaucoma (self-reported)	1.5	1.7	4.8	-1.2	-2.2	-1.4	-1.3	-1.5	-1.1	0.8	-1.3	-1.2	-1.4	-1.2	-1.4	-1.2	-1.2	-1.2	-1.2	0.9	-1.2
LDL Cholesterol	1.4	2.3	3.1	-1.7	-0.3	-1.6	-1.7	-1.4	-1.7	0.5	-1.2	-1.2	-1.8	-1.7	-1.6	-1.6	-1.7	-1.7	-1.6	1.4	-1.5
Schizophrenia (2014)	1.4	3.1	6.6	1.6	1.1	1.7	1.6	2.1	1.5	-2.6	1.8	2.5	1.6	1.5	1.5	1.9	1.7	1.9	1.5	-1.6	1.7
Impedance of leg (right)	1.4	6.6	11.6	-3.1	-0.9	-3.3	-2.9	-1.9	-3.0	-1.2	-1.4	-0.9	-2.7	-3.0	-2.5	-2.3	-3.1	-3.0	-2.9	3.4	-2.2
Medication: Atenolol	1.4	1.8	5.2	-1.1	-1.0	-1.7	-1.4	-1.8	-1.3	-0.4	-0.5	-1.7	-1.4	-1.2	-0.8	-1.2	-1.2	-1.4	-1.1	2.3	-1.3
Impedance of leg (left)	1.4	6.8	12.2	-3.1	-1.1	-3.4	-3.0	-1.9	-3.0	-1.3	-1.8	-0.9	-2.8	-3.0	-2.5	-2.4	-3.1	-3.0	-2.9	3.5	-2.3
Allergy	1.4	3.3	5.6	1.6	2.4	2.3	1.7	1.8	1.6	-0.6	1.6	2.3	1.6	1.7	1.4	1.8	1.8	1.5	1.8	-2.4	1.9
Headache pain in last month	1.4	2.4	6.2	-1.7	-2.5	-0.6	-1.6	-0.9	-1.7	0.8	-1.4	-1.9	-1.6	-1.8	-1.2	-1.7	-1.8	-1.8	-1.6	0.6	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	5.0	0.9	2.1	1.0	1.0	1.7	1.0	-2.2	0.7	1.8	1.0	1.0	0.6	1.4	1.0	1.2	0.8	-1.3	1.1
Mean time to correctly identify matches	1.4	2.7	12.2	1.2	-0.3	1.2	1.3	1.6	1.3	-3.5	1.2	2.6	1.4	1.3	1.1	1.9	1.5	1.6	1.5	-0.9	1.6
Ever had bowel cancer screening	1.4	1.6	3.7	1.3	1.9	1.1	1.2	1.0	1.4	-1.9	0.5	1.2	1.2	1.2	0.8	1.6	1.3	1.2	1.2	-0.8	1.3
Qualifications: nursing, teaching	1.4	2.1	4.0	1.5	1.7	0.7	1.5	1.1	1.4	-1.3	2.0	1.4	1.6	1.6	1.3	1.6	1.6	1.4	1.8	-0.1	1.5
Guilty feelings	1.4	2.0	5.4	1.2	1.2	1.5	1.2	1.8	1.2	-1.9	-0.1	2.3	1.2	1.2	0.7	1.6	1.4	1.3	1.4	-1.7	1.4
Medication: Lisinopril	1.4	1.8	3.0	-1.5	-0.6	-0.8	-1.5	-1.6	-1.5	-0.4	-0.7	-1.7	-1.5	-1.5	-1.5	-1.4	-1.5	-1.2	-1.5	0.8	-1.5
Schizophrenia (2018)	1.3	2.7	4.7	1.6	1.2	1.3	1.6	2.2	1.5	-1.9	1.6	2.1	1.7	1.5	1.0	1.8	1.7	2.0	1.6	-1.3	1.6
Waist Hip Ratio (WHR)	1.3	5.7	15.3	-2.3	-2.6	-3.2	-2.4	-0.9	-2.4	-3.0	-2.7	0.4	-2.0	-2.4	-2.3	-1.8	-2.4	-2.2	-2.2	3.9	-1.8
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	5.4	-1.1	-1.5	-2.0	-1.2	-1.3	-1.0	-1.1	-1.3	-0.3	-1.3	-1.1	-0.6	-0.9	-1.1	-0.9	-1.4	2.3	-1.1
Alcohol intake versus 10 years previously	1.3	1.9	3.0	-1.6	-1.0	-1.4	-1.4	-1.2	-1.6	0.5	-1.5	-1.7	-1.2	-1.5	-0.9	-1.7	-1.5	-1.3	-1.5	1.3	-1.7
Prospective memory result	1.3	1.6	3.8	-1.1	-1.6	-1.3	-1.2	-1.3	-1.1	0.7	-0.8	-1.3	-1.3	-1.2	-0.9	-1.2	-1.2	-1.1	-1.4	2.0	-1.4
Comparative body size at age 10	1.3	3.7	10.0	2.0	1.0	1.8	1.9	1.7	1.9	-3.2	1.7	2.1	1.9	1.8	2.0	2.2	1.9	2.0	1.7	-1.2	1.8
Mother’s age at death	1.3	1.7	3.9	1.1	1.5	1.7	1.1	0.6	1.2	-1.3	2.0	1.2	1.0	1.1	1.0	1.3	1.2	1.1	1.1	-1.8	1.2
Ulcerative Colitis	1.2	1.7	3.2	1.4	1.8	1.3	1.1	1.2	1.5	0.9	1.6	1.3	0.9	1.2	1.6	1.3	1.3	1.2	1.1	-1.5	1.2
Smoking Status	1.2	2.9	4.3	-1.8	-2.0	-1.9	-1.7	-0.9	-1.8	-1.9	-1.4	0.1	-1.6	-1.9	-2.0	-1.4	-1.8	-1.8	-1.8	2.1	-1.6
Serious illness, injury or assault to yourself	1.2	1.5	6.7	-1.0	-2.6	-0.6	-1.1	-0.7	-1.1	-2.2	-1.9	-0.3	-1.1	-1.1	-0.3	-0.6	-1.0	-1.2	-1.1	0.8	-0.9
Father’s age at death	1.2	1.6	2.5	1.2	0.8	1.4	1.4	1.6	1.1	-1.1	1.1	1.3	1.5	1.3	1.0	1.3	1.2	1.1	1.3	-1.5	1.3
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	2.5	-1.3	-1.3	-0.9	-1.4	-1.4	-1.4	0.0	-0.4	-1.0	-1.4	-1.5	-1.1	-1.4	-1.4	-1.3	-1.6	1.2	-1.5
Angina (self-reported)	1.2	1.6	3.6	-1.4	-1.9	-1.3	-1.3	-0.8	-1.4	-1.4	-0.7	-0.6	-1.3	-1.4	-1.1	-1.1	-1.3	-1.1	-1.6	1.5	-1.2
Ever smoked	1.2	2.1	3.5	-1.6	-1.9	-1.5	-1.4	-0.7	-1.6	-0.6	-1.4	-0.3	-1.3	-1.6	-1.6	-1.5	-1.5	-1.7	-1.6	1.6	-1.4
Ever had hysterectomy (womb removed)	1.1	1.3	3.7	0.8	-0.0	0.9	1.0	1.5	0.9	-1.9	0.7	1.4	1.2	1.0	1.1	1.3	1.0	1.2	1.2	-0.9	1.2
Maternal smoking around birth	1.1	1.6	2.8	-1.2	0.3	-1.2	-1.1	-1.2	-1.2	1.6	-1.2	-1.6	-1.1	-1.2	-1.7	-1.4	-1.2	-1.3	-1.2	1.2	-1.3
Medication: Seretide 50 evohaler	1.1	1.2	3.9	-0.8	-2.0	-1.4	-1.0	-0.8	-0.8	-0.4	-1.9	-0.5	-1.0	-0.8	-0.0	-0.8	-0.9	-0.9	-1.2	1.9	-0.9
Leg pain on walking	1.1	1.4	3.0	1.1	0.1	1.3	1.2	1.1	1.2	0.8	1.4	1.2	1.2	1.2	1.7	1.1	1.2	1.2	1.1	-0.9	1.2
Diabetes diagnosed by doctor	1.1	1.7	5.4	-1.1	-0.7	-1.1	-1.4	-1.2	-1.1	1.6	-2.3	-1.2	-1.5	-1.3	-0.9	-1.3	-1.4	-1.1	-1.3	1.1	-1.2
Angina	1.0	1.4	3.0	-1.3	-1.7	-1.2	-1.2	-0.6	-1.3	-1.4	-0.7	-0.6	-1.2	-1.3	-1.0	-1.0	-1.2	-1.1	-1.5	1.3	-1.1
Past tobacco smoking	1.0	1.9	3.1	1.7	1.5	1.0	1.5	0.8	1.7	0.9	1.0	0.5	1.4	1.6	1.8	1.4	1.5	1.6	1.7	-0.8	1.5
Pain all over the body in last month	1.0	1.1	2.6	-1.2	-0.5	-1.0	-1.1	-1.1	-1.1	-0.7	-1.6	-0.6	-1.0	-1.1	-1.2	-1.0	-1.0	-1.0	-1.0	1.3	-0.9
Hip circumference	1.0	4.5	10.5	2.1	1.1	3.2	2.2	1.2	2.2	2.5	2.1	1.0	1.9	2.1	1.9	1.7	2.2	2.1	2.0	-3.2	1.8
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	3.2	-1.4	-1.5	-1.6	-1.4	-0.8	-1.3	-1.3	-1.3	-0.2	-1.3	-1.5	-1.2	-1.0	-1.3	-1.1	-1.5	1.8	-1.2
Mouth/teeth dental problems: Loose teeth	1.0	1.2	3.6	1.1	1.2	0.2	1.0	1.3	1.2	-1.0	0.5	1.9	1.2	1.1	0.8	1.3	1.2	1.1	1.2	-0.1	1.3
Migraine (self-reported)	1.0	1.3	3.8	-1.1	-1.1	-1.6	-1.1	-1.1	-1.0	-0.3	-1.4	-0.5	-1.1	-1.0	-1.9	-0.9	-1.0	-1.1	-0.8	1.2	-0.9
Alcohol intake frequency.	1.0	2.3	8.1	-1.6	-2.8	-1.5	-1.5	-0.9	-1.5	0.4	-1.6	-1.1	-1.3	-1.5	-1.3	-1.5	-1.5	-1.4	-1.5	1.5	-1.5
Family relationship satisfaction	1.0	1.2	2.5	1.0	1.4	1.5	1.1	1.0	1.1	-0.5	1.4	0.6	1.0	1.0	0.7	1.1	1.0	0.9	1.2	-1.6	1.0
Mood swings	1.0	1.8	3.4	-1.5	-1.0	-0.7	-1.4	-1.3	-1.4	0.9	-1.1	-1.2	-1.5	-1.6	-1.8	-1.5	-1.5	-1.5	-1.6	0.4	-1.4
Back pain experienced in last month	1.0	1.5	2.8	-1.1	-1.7	-1.2	-1.1	-1.4	-1.2	1.3	-0.5	-1.6	-1.1	-1.1	-1.2	-1.3	-1.1	-1.3	-1.1	1.1	-1.3
Osteoarthritis (self-reported)	1.0	1.3	2.4	-1.2	-1.1	-1.2	-1.2	-1.2	-1.2	-1.3	-0.8	-0.5	-1.2	-1.2	-0.8	-0.9	-1.1	-1.3	-1.2	1.6	-1.1
Medication: Gliclazide	1.0	1.1	2.4	-1.0	-0.9	-1.6	-1.2	-0.7	-1.1	-0.9	-1.3	-0.6	-1.2	-1.1	-1.1	-0.8	-1.2	-0.9	-1.1	1.4	-0.8
Hearing aid user	1.0	1.1	5.0	-1.0	-2.2	-0.4	-1.1	-0.5	-1.1	0.1	-0.9	-0.7	-1.2	-1.1	-0.9	-1.1	-1.1	-1.2	-1.3	0.1	-1.1
Commuting to job workplace: Public transport	1.0	1.2	4.8	1.1	2.2	0.8	1.0	0.9	1.1	-0.0	0.8	1.1	1.0	1.1	1.0	1.1	1.0	1.2	1.2	-0.9	1.0
Coronary Artery Disease (CAD)	0.9	1.1	7.1	1.1	0.9	0.8	0.9	0.9	1.0	0.3	0.7	0.9	1.0	0.8	2.7	1.0	0.9	0.8	0.9	0.6	1.0
Length of working week for main job	0.9	1.0	2.6	-0.8	-1.2	-1.5	-0.8	-1.0	-0.7	-0.7	-1.5	-0.7	-0.7	-0.7	-1.6	-0.6	-0.7	-0.6	-0.7	1.2	-0.7
Eye problems/disorders: Cataract	0.9	1.1	1.8	-1.3	-1.3	-0.7	-1.1	-0.6	-1.1	-1.1	-0.8	0.1	-1.1	-1.3	-0.9	-0.8	-1.2	-1.3	-1.3	0.7	-1.0
Illnesses of father: High blood pressure	0.9	1.2	2.6	-0.9	-0.6	-1.5	-1.0	-0.8	-0.9	0.0	-1.6	-1.4	-1.0	-1.0	-0.8	-1.0	-1.2	-0.9	-1.0	1.6	-0.9
HbA1C	0.8	0.9	1.8	-0.8	-0.6	-1.3	-0.9	-0.9	-0.8	1.0	-0.9	-0.8	-0.8	-0.8	-0.8	-0.9	-0.8	-0.9	-1.0	1.3	-0.9
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	6.3	-0.9	-2.5	-0.6	-0.8	-0.8	-0.8	-0.4	-1.1	-0.7	-0.8	-0.9	-0.7	-0.8	-0.9	-1.0	-1.1	0.6	-0.9
High blood pressure (mother)	0.8	1.1	3.0	-1.1	-0.8	-1.0	-1.0	-1.1	-1.0	0.9	-0.7	-1.7	-1.1	-1.0	-0.7	-1.2	-1.1	-1.0	-1.2	0.8	-1.1
Noisy workplace	0.8	1.0	4.5	-0.8	-2.1	-1.2	-1.0	-0.6	-0.9	0.2	-0.7	-0.6	-1.0	-0.9	-0.2	-0.9	-1.0	-0.7	-1.1	1.7	-0.8
Birth weight of first child	0.8	1.4	3.6	1.1	0.5	1.8	1.3	0.9	1.2	0.4	0.8	0.3	1.2	1.3	1.2	1.1	1.3	1.3	1.3	-1.9	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	4.1	-0.7	-1.6	-1.8	-0.9	-0.4	-0.8	-1.1	-0.6	0.2	-0.7	-0.8	-0.5	-0.5	-0.8	-0.8	-0.6	2.0	-0.5
Friendships satisfaction	0.8	1.0	1.6	1.0	1.1	0.6	1.1	0.9	1.0	1.2	1.0	0.5	1.2	1.1	1.1	0.9	1.0	0.9	1.2	-0.4	1.0
Ever taken oral contraceptive pill	0.8	0.9	2.0	1.0	0.4	0.6	1.1	1.3	1.1	-0.0	0.2	1.4	1.2	1.1	0.4	1.1	1.1	1.2	1.0	-0.4	1.2
Commuting to job workplace: Cycle	0.8	0.9	2.6	0.8	1.0	1.2	1.0	1.0	0.9	0.9	0.6	0.6	1.0	0.9	0.8	0.7	0.9	1.0	1.0	-1.6	0.9
Supplements: Calcium	0.8	0.8	2.4	1.0	-0.2	0.3	1.2	1.6	1.1	0.3	0.3	0.7	1.4	1.0	0.7	1.0	0.9	1.0	1.0	0.1	0.9
Pack years of smoking	0.8	1.2	3.4	-1.1	0.4	-0.8	-1.0	-0.7	-1.2	-1.0	-1.8	-1.0	-0.9	-1.1	-1.4	-1.1	-1.0	-1.1	-1.2	0.6	-1.1
Irritable Bowel Disease (IBD)	0.7	1.7	3.0	1.4	1.7	1.7	1.3	1.0	1.5	-0.7	1.1	0.9	1.1	1.3	1.5	1.4	1.5	1.3	1.0	-1.6	1.1
Reaction Time	0.7	1.3	4.6	0.9	-1.1	1.0	0.9	0.9	0.9	-2.1	0.9	1.8	0.9	0.9	1.1	1.3	1.1	1.1	1.0	-0.5	1.1
Breast Cancer	0.7	1.7	2.6	-1.5	-1.6	-1.4	-1.5	-1.3	-1.4	-0.5	-1.1	-1.0	-1.5	-1.4	-0.7	-1.3	-1.4	-1.3	-1.3	1.4	-1.3
Allergy or Eczema	0.7	1.9	6.2	-1.3	-2.5	-1.1	-1.2	-1.2	-1.4	0.5	-0.7	-1.5	-1.1	-1.4	-1.8	-1.4	-1.4	-1.1	-1.4	0.9	-1.5
Hypothyroidism (self reported)	0.7	1.6	3.9	1.0	2.0	1.6	1.2	1.4	0.9	-0.9	1.3	1.3	1.3	1.0	0.6	1.2	1.1	1.1	1.1	-1.6	1.1
Stomach or abdominal pain in last month	0.7	0.8	1.4	0.9	1.1	0.6	0.9	0.7	1.0	-1.2	1.0	0.5	0.9	1.0	0.3	1.1	1.0	1.2	1.0	-0.7	0.9
Hearing difficulty/problems with background noise	0.7	1.1	3.2	0.7	0.8	1.0	0.9	1.4	0.8	-1.8	1.2	1.5	0.9	0.8	0.4	1.1	0.9	1.0	0.8	-0.8	0.9
Worrier / anxious feelings	0.7	1.3	8.7	0.9	3.0	1.1	0.8	0.7	1.0	1.3	0.5	0.9	0.7	0.9	1.2	0.7	0.9	0.9	0.8	-0.8	0.9
Tense / ‘highly strung’	0.7	1.2	4.0	-0.9	-0.3	-1.0	-1.0	-0.7	-0.9	1.7	-2.0	-1.4	-1.0	-0.9	-1.1	-1.1	-1.0	-0.7	-1.0	1.1	-1.0
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	2.8	1.0	1.2	1.7	1.1	1.4	0.9	-0.4	1.3	1.6	1.1	1.0	0.9	1.1	1.0	0.9	1.0	-1.4	1.1
Leg fat mass (right)	0.7	2.6	5.7	-1.7	-2.4	-0.7	-1.8	-1.9	-1.7	0.8	-0.9	-1.0	-2.0	-1.8	-1.2	-1.7	-1.7	-1.6	-1.8	0.8	-1.7
Smoking status: Previous	0.7	1.0	1.6	-1.2	-1.3	-0.4	-1.1	-0.8	-1.2	-0.1	-0.3	-0.7	-1.1	-1.1	-1.3	-1.2	-1.1	-1.2	-1.2	0.1	-1.1
Breast cancer (self-reported)	0.7	0.8	5.0	0.8	0.6	0.4	0.7	0.2	0.8	2.2	1.5	-0.2	0.6	0.8	1.0	0.4	0.8	1.0	0.6	-0.2	0.5
Leg fat mass (left)	0.7	2.8	6.0	-1.8	-2.5	-0.9	-1.9	-2.0	-1.8	0.8	-1.2	-1.2	-2.1	-1.9	-1.3	-1.8	-1.8	-1.7	-1.8	1.0	-1.8
Depression (Nagel 2018)	0.6	0.9	1.8	-0.9	-1.3	-0.8	-1.1	-0.8	-0.9	-0.7	-1.1	-0.5	-1.2	-1.0	-0.9	-0.8	-1.0	-1.0	-1.1	0.9	-0.8
Alzheimer’s Disease (in mother)	0.6	0.7	2.4	0.7	-0.5	0.2	0.5	1.2	0.7	-1.1	0.8	1.5	0.7	0.6	1.3	0.9	0.7	0.6	0.7	0.2	0.8
Primary Biliary Cirrhosis	0.6	0.9	2.0	-0.8	-1.0	-1.1	-1.1	-0.4	-1.0	-1.0	-0.5	-0.7	-1.0	-1.0	0.0	-0.9	-1.0	-0.9	-1.1	1.4	-1.0
Blood Eosinophil Count	0.6	4.8	7.5	-2.0	-1.9	-2.2	-2.0	-2.7	-2.0	1.7	-2.6	-2.7	-2.0	-2.0	-1.9	-2.2	-2.1	-1.9	-2.0	2.7	-2.3
Medication: Metformin	0.6	0.8	3.6	-0.8	-0.8	-0.6	-1.0	-0.7	-0.9	0.6	-1.9	-0.3	-1.1	-1.0	-0.5	-0.8	-1.1	-0.7	-1.0	0.8	-0.8
Pack years adult smoking proportion	0.6	1.0	3.3	-1.0	0.5	-0.8	-0.9	-0.6	-1.0	-1.0	-1.8	-0.8	-0.9	-1.0	-1.2	-0.9	-0.9	-1.0	-1.1	0.6	-1.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.0	0.6	0.1	0.9	0.9	1.4	0.7	-0.6	0.7	1.0	1.1	0.7	0.7	0.9	0.7	0.8	0.9	-1.2	0.8
Hayfever, allergic rhinitis or eczema	0.6	1.3	4.4	-0.9	-2.1	-1.4	-1.0	-1.1	-1.0	0.2	-0.6	-1.4	-0.8	-1.0	-1.1	-1.0	-1.1	-0.9	-1.0	1.3	-1.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.0	0.9	1.0	1.4	0.9	0.4	1.0	-0.3	0.0	0.7	0.7	0.8	1.0	0.9	0.8	0.9	0.7	-1.1	0.8
Chronic bronchitis/emphysema (father)	0.6	0.7	1.8	-0.9	-0.4	-0.9	-1.1	-0.5	-0.9	-0.4	-0.9	-0.3	-1.0	-1.0	0.1	-0.8	-0.9	-1.0	-0.8	1.3	-0.9
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.7	-0.9	0.1	-1.1	-1.0	-0.7	-1.0	-0.7	-1.2	-0.6	-0.9	-1.0	-0.5	-0.8	-0.9	-0.8	-1.1	1.3	-1.0
Number of full sisters	0.6	0.7	4.2	-0.5	-0.9	-1.2	-0.5	-0.5	-0.4	2.1	-0.3	-1.2	-0.4	-0.4	0.4	-0.8	-0.6	-0.4	-0.5	1.5	-0.5
Commuting to job workplace: Walk	0.6	0.7	2.8	0.8	1.1	1.1	0.8	0.4	0.8	1.1	-0.0	0.1	0.5	0.8	0.4	0.6	0.9	0.7	0.7	-1.7	0.6
Alcohol drinker status: Never	0.6	0.7	3.5	0.6	-0.8	0.6	0.5	1.2	0.5	-1.6	-0.1	1.9	0.4	0.6	0.4	0.8	0.7	0.5	0.5	-0.6	0.7
Impedance of whole body	0.6	3.1	8.3	-2.1	-0.7	-2.7	-2.0	-0.9	-2.1	-1.1	-0.6	-0.0	-1.7	-2.0	-1.4	-1.4	-2.1	-2.2	-1.9	2.9	-1.3
Alzheimer’s Disease (including proxy)	0.5	0.7	4.6	0.6	-0.2	-0.1	0.3	0.7	0.8	-2.1	0.2	1.8	0.5	0.4	0.9	1.0	0.6	0.6	0.5	0.3	0.7
Lupus	0.5	0.8	1.4	-1.0	0.4	-0.8	-1.0	-0.1	-1.1	-0.9	-0.4	-0.2	-0.9	-1.1	-1.1	-0.8	-1.1	-1.2	-1.0	1.0	-0.9
Blood Red Count	0.5	5.2	29.7	-1.3	-0.0	-1.9	-1.2	-3.0	-1.3	5.5	-0.3	-4.8	-1.2	-1.1	-1.0	-2.4	-1.3	-1.5	-1.1	1.9	-2.0
Sensitivity / hurt feelings	0.5	0.8	1.8	-1.2	0.1	-0.4	-1.2	-0.4	-1.1	0.9	-0.0	0.7	-1.3	-1.2	-1.2	-1.0	-1.1	-1.0	-1.1	0.1	-0.7
Hearing difficulty/problems: Yes	0.5	0.7	2.2	0.7	-0.0	-0.2	0.7	1.2	0.7	-1.4	0.2	1.5	0.9	0.7	0.6	1.0	0.7	0.7	0.8	0.7	1.0
Happiness	0.5	0.6	2.8	0.7	1.7	0.8	0.8	0.3	0.7	0.4	0.8	-0.1	0.8	0.7	0.4	0.6	0.8	0.7	0.9	-0.8	0.7
Arm fat mass (right)	0.5	1.9	4.8	-1.3	-2.2	-0.3	-1.4	-1.5	-1.4	1.7	-0.8	-1.2	-1.6	-1.4	-0.9	-1.6	-1.4	-1.3	-1.4	0.3	-1.4
Neck or shoulder pain in last month	0.5	0.6	4.7	-0.7	-1.6	-0.3	-0.5	-0.0	-0.7	-2.2	-0.1	-0.1	-0.4	-0.6	-0.7	-0.3	-0.5	-0.6	-0.6	0.7	-0.5
Suffer from ‘nerves’	0.5	0.8	1.9	-0.7	1.0	-0.8	-0.9	-0.9	-0.7	-0.6	-1.4	-0.9	-0.9	-0.9	-1.1	-0.6	-0.8	-0.8	-1.1	0.8	-0.8
Age at last live birth	0.5	0.7	2.4	0.7	1.6	0.8	0.7	0.8	0.9	1.4	0.3	0.6	0.5	0.8	0.7	0.6	0.8	0.9	0.6	-1.0	0.7
Smoking status: Current	0.5	0.7	5.1	-0.3	0.0	-1.2	-0.2	0.3	-0.2	-2.3	-1.4	1.1	0.1	-0.3	-0.3	0.2	-0.2	-0.1	-0.2	1.7	0.0
Basal cell carcinoma (self-reported)	0.5	0.6	2.3	0.3	0.7	1.4	0.5	0.6	0.4	0.7	1.5	0.1	0.5	0.4	1.0	0.2	0.5	0.4	0.5	-1.5	0.3
Alcohol drinker status: Previous	0.5	0.6	1.6	-0.6	-1.2	-0.9	-0.6	-0.3	-0.7	0.7	-1.1	-0.3	-0.4	-0.7	-0.5	-0.7	-0.8	-0.7	-0.7	1.1	-0.5
Bipolar Disorder or Schizophrenia	0.4	1.1	1.8	1.0	0.4	1.1	1.0	1.3	1.0	-0.9	1.2	1.4	1.1	0.9	0.9	1.1	1.0	1.2	0.9	-0.9	0.9
Medication for hormone replacement therapy	0.4	0.5	2.2	0.4	-0.7	1.0	0.6	0.9	0.5	0.7	0.6	0.5	0.5	0.5	0.7	0.4	0.5	0.4	0.6	-1.5	0.5
Diabetes (mother)	0.4	0.5	1.0	-0.8	-0.4	0.1	-0.8	-0.4	-0.9	-1.0	-0.2	-0.6	-0.8	-0.9	-0.4	-0.7	-0.8	-1.0	-0.8	-0.5	-0.8
Current tobacco smoking	0.4	0.7	4.7	-0.1	0.1	-1.1	-0.1	0.3	-0.1	-2.2	-1.2	1.2	0.2	-0.1	-0.2	0.3	-0.1	0.1	-0.0	1.7	0.2
Waist circumference	0.4	1.5	3.7	-1.3	-1.9	-0.6	-1.4	-1.1	-1.3	-0.3	-1.3	-0.3	-1.5	-1.4	-1.4	-1.2	-1.2	-1.1	-1.4	0.8	-1.2
Number of incorrect matches in round	0.4	0.7	2.3	-0.7	-1.5	-0.7	-0.7	-1.2	-0.7	-0.1	-1.2	-1.3	-0.7	-0.7	-1.0	-0.7	-0.6	-0.8	-0.5	0.5	-0.7
Pulse rate	0.4	0.7	2.7	-0.5	-1.0	-1.1	-0.8	-1.1	-0.7	-0.0	-0.2	-0.6	-0.9	-0.7	-0.3	-0.7	-0.8	-0.8	-0.8	1.6	-0.8
Depression (self-reported)	0.4	0.5	1.1	0.8	-0.0	0.3	0.8	0.8	0.9	0.8	0.7	0.5	0.9	0.8	0.2	0.7	0.8	0.8	1.1	-0.3	0.7
Gout (self-reported)	0.4	0.6	2.7	0.5	1.6	1.3	0.5	0.1	0.6	0.7	0.6	0.2	0.3	0.6	0.5	0.4	0.6	0.7	0.8	-1.5	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.7	-0.8	-1.3	-0.4	-0.6	-0.5	-0.7	-0.4	-0.7	0.0	-0.6	-0.7	-1.6	-0.5	-0.7	-0.6	-0.4	0.1	-0.6
Age at first live birth	0.4	0.6	1.1	0.8	0.8	1.0	0.8	0.7	0.8	-0.2	1.1	0.5	0.8	0.8	0.7	0.7	0.8	0.9	0.8	-1.0	0.7
Supplements: Vitamin C	0.4	0.5	4.2	0.1	-0.6	-0.3	0.4	0.3	0.2	-2.1	0.2	0.4	0.6	0.3	-1.3	0.6	0.4	0.3	0.4	-0.6	0.4
Loneliness, isolation	0.4	0.5	2.4	-0.5	-0.0	-0.7	-0.4	-0.5	-0.5	1.6	-1.3	-0.4	-0.4	-0.5	-0.9	-0.8	-0.5	-0.4	-0.5	0.9	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.5	0.7	-0.8	0.2	0.6	0.7	0.7	0.1	-0.5	1.1	0.6	0.7	1.2	0.7	0.7	0.9	0.7	0.4	0.9
Arm fat mass (left)	0.4	1.6	4.8	-1.2	-2.2	-0.3	-1.3	-1.5	-1.2	1.5	-0.7	-1.1	-1.5	-1.3	-0.8	-1.4	-1.2	-1.2	-1.3	0.3	-1.3
Irritability	0.4	0.7	2.7	0.4	1.6	0.8	0.6	1.3	0.5	-0.9	0.2	1.4	0.6	0.4	0.1	0.8	0.5	0.6	0.5	-0.9	0.8
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.9	-0.7	-0.2	-0.5	-0.8	-0.6	-0.7	0.5	-0.6	-0.6	-0.9	-0.8	-1.0	-0.7	-0.8	-0.8	-0.8	0.6	-0.7
Diastolic blood pressure, automated reading	0.4	1.4	5.0	1.1	2.2	0.1	0.8	0.5	1.1	1.9	1.6	0.7	0.8	1.1	1.4	0.8	0.9	1.0	1.3	0.1	1.0
Myopia	0.4	0.6	1.5	0.6	1.2	0.5	0.7	0.9	0.7	-0.2	-0.0	1.2	0.7	0.8	0.5	0.8	0.8	0.8	0.9	-0.9	0.9
Mean Putamen Volume	0.3	0.4	1.5	-0.6	-0.6	-0.8	-0.5	-0.4	-0.6	0.3	0.5	-0.2	-0.4	-0.6	-1.2	-0.6	-0.6	-0.7	-0.5	0.6	-0.5
Neuroticism	0.3	0.7	2.0	-0.9	0.8	-0.3	-1.0	-0.3	-0.8	-0.7	-1.4	0.1	-1.1	-1.0	-1.4	-0.6	-0.9	-0.9	-1.0	0.2	-0.6
Chronotype (morning person)	0.3	0.7	7.6	-0.5	2.8	0.1	-0.3	-0.5	-0.5	0.1	-0.1	-0.9	-0.4	-0.4	-1.2	-0.5	-0.4	-0.3	-0.7	-0.4	-0.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	2.4	-0.5	-0.9	-0.4	-0.5	-0.4	-0.5	0.3	-1.5	-0.4	-0.6	-0.6	-0.9	-0.6	-0.5	-0.4	-0.8	0.3	-0.5
Systolic blood pressure, automated reading	0.3	0.8	4.1	-0.5	-0.1	-1.3	-1.0	-1.1	-0.6	2.0	0.4	-0.6	-1.1	-0.6	-0.4	-0.9	-0.8	-0.6	-0.4	1.3	-0.6
Diabetes (father)	0.3	0.4	1.0	-0.6	-1.0	-0.8	-0.7	-0.2	-0.8	-0.7	-0.2	0.3	-0.5	-0.8	-0.3	-0.6	-0.8	-1.0	-0.5	0.6	-0.4
Townsend deprivation index at recruitment	0.3	0.4	1.0	-0.6	-1.0	-0.5	-0.6	-0.4	-0.6	0.2	-0.4	0.1	-0.7	-0.6	-0.7	-0.7	-0.6	-0.7	-0.6	0.5	-0.5
Relative age voice broke	0.3	0.5	2.9	-0.7	-1.7	-0.2	-0.7	-0.0	-0.8	0.5	-0.8	0.2	-0.8	-0.7	-0.5	-0.7	-0.6	-0.6	-0.7	0.1	-0.5
Alcohol usually taken with meals	0.3	0.4	1.1	0.9	0.1	0.1	0.8	0.4	0.9	1.1	0.2	0.1	0.9	0.8	0.1	0.6	0.7	0.6	0.8	-0.3	0.6
Nervous feelings	0.3	0.7	5.4	0.4	2.3	0.5	0.5	1.1	0.4	-0.8	-0.4	0.9	0.4	0.5	0.1	0.6	0.5	0.5	0.2	-0.8	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	2.4	-0.5	-0.4	-0.8	-0.6	-0.4	-0.6	0.1	-1.5	-0.2	-0.5	-0.6	-0.6	-0.5	-0.6	-0.7	-0.6	1.0	-0.5
Time employed in main current job	0.3	0.3	1.2	-0.3	1.1	0.7	-0.2	-0.7	-0.3	-0.6	0.8	-1.0	-0.3	-0.4	-0.5	-0.2	-0.2	-0.4	-0.2	-0.8	-0.5
Breastfed as a baby	0.3	0.4	2.0	0.2	-0.6	0.9	0.2	-0.0	0.2	-1.1	1.1	0.5	0.1	0.2	0.1	0.4	0.2	0.2	-0.1	-1.4	0.3
Blood clot in the leg (DVT)	0.3	0.4	1.3	0.5	-0.6	0.6	0.6	0.4	0.6	1.1	0.3	0.4	0.6	0.7	0.7	0.3	0.7	0.7	0.5	-0.7	0.6
Number of full brothers	0.3	0.4	1.8	-0.7	-1.3	-0.0	-0.7	-0.6	-0.7	-0.8	0.2	-0.5	-0.7	-0.8	-0.3	-0.6	-0.7	-0.6	-0.6	0.0	-0.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.1	-0.5	-0.6	-0.5	-0.5	-0.6	-0.6	-1.1	-1.0	-0.2	-0.6	-0.5	-0.6	-0.4	-0.5	-0.5	-0.6	0.6	-0.5
Risk taking	0.3	0.5	4.5	0.0	-2.1	-0.5	-0.1	0.1	-0.1	-1.4	-0.6	0.6	-0.1	-0.1	-0.8	0.2	0.1	-0.2	-0.2	0.2	0.0
Ever depressed for a whole week	0.3	0.3	1.6	0.4	0.7	1.2	0.3	0.1	0.5	0.3	0.9	0.1	0.1	0.4	0.5	0.4	0.5	0.6	0.6	-1.0	0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.5	0.5	-0.7	0.6	0.6	0.5	0.6	1.2	0.2	0.3	0.6	0.7	0.8	0.3	0.6	0.6	0.5	-0.6	0.6
Schizophrenia vs Biploar Disorder	0.2	0.3	3.7	-0.3	0.4	0.2	-0.2	0.1	-0.4	-1.9	-0.3	0.4	-0.2	-0.2	-0.7	0.0	-0.0	0.0	-0.1	-0.5	0.1
Worry (Nagel 2018)	0.2	0.5	8.0	0.0	2.8	-0.0	-0.1	0.0	-0.0	0.9	-0.6	-0.3	-0.4	-0.0	-0.3	-0.1	-0.0	-0.0	-0.2	0.1	0.0
Major Depression (MDD)	0.2	0.3	1.3	0.5	0.4	-0.3	0.3	-0.1	0.5	0.4	-1.1	-0.2	0.3	0.4	0.6	0.4	0.4	0.6	0.5	0.6	0.3
Neuroticism (2016)	0.2	0.3	2.5	-0.2	0.8	0.1	-0.0	-0.0	-0.1	0.8	-1.6	-0.1	-0.1	0.1	-0.9	-0.2	-0.1	0.2	0.1	-0.3	0.1
Rheumatoid Arthritis	0.2	0.3	1.7	-0.1	-0.1	0.4	0.0	0.8	-0.1	-1.3	-1.2	0.6	-0.0	0.0	0.4	0.2	0.0	0.0	-0.2	-0.5	0.1
Triglycerides	0.2	0.2	0.9	-0.5	-0.1	0.0	-0.3	-0.7	-0.4	1.0	0.6	-0.8	-0.2	-0.4	-0.4	-0.6	-0.5	-0.6	-0.2	-0.0	-0.4
Systolic Blood Pressure	0.2	1.1	12.2	0.1	0.5	-0.3	-0.2	-0.5	0.1	3.5	2.2	-1.1	-0.4	0.1	0.8	-0.4	-0.1	-0.1	0.4	0.1	-0.0
Tanning	0.2	2.8	4.7	1.9	1.5	1.6	1.8	1.8	1.8	0.3	1.5	1.9	1.8	1.8	2.2	1.7	1.8	1.5	1.7	-1.1	1.8
Relative age of first facial hair	0.2	0.4	2.0	-0.7	-1.4	-0.5	-0.7	0.4	-0.9	-0.1	0.7	0.7	-0.7	-0.7	-0.2	-0.5	-0.7	-0.5	-0.5	0.5	-0.3
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.9	-0.2	-0.9	0.9	0.0	0.0	-0.1	1.4	0.1	-0.5	0.0	-0.1	0.2	-0.3	-0.1	-0.1	-0.1	-1.2	-0.2
Vitamin and mineral supplements	0.2	0.3	1.4	-0.2	0.5	0.1	-0.4	-0.7	-0.3	1.2	0.0	-0.9	-0.5	-0.3	-0.2	-0.6	-0.3	-0.3	-0.4	0.1	-0.5
Supplements: Zinc	0.2	0.2	1.0	-0.0	-1.0	-0.3	0.3	0.8	-0.0	-0.9	0.4	0.8	0.6	0.0	-0.6	0.3	0.1	0.0	0.2	0.1	0.2
Age when periods started (menarche)	0.2	0.6	2.3	-0.8	-1.0	-0.5	-0.6	-0.1	-0.7	1.5	-0.9	-0.9	-0.5	-0.7	-1.0	-0.8	-0.8	-0.7	-0.6	0.1	-0.6
Had other major operations	0.2	0.3	1.6	-0.4	-0.9	-0.3	-0.3	-0.6	-0.3	1.3	0.1	-0.9	-0.2	-0.4	-0.1	-0.5	-0.3	-0.3	-0.2	0.4	-0.5
Number of live births	0.2	0.3	0.8	0.3	0.8	0.5	0.5	0.9	0.4	0.0	0.3	0.9	0.5	0.4	-0.6	0.5	0.4	0.4	0.4	-0.5	0.5
Mouth/teeth dental problems: Dentures	0.2	0.3	1.4	-0.3	0.0	-0.4	-0.3	-0.5	-0.3	0.9	-0.7	-1.2	-0.3	-0.4	-0.5	-0.5	-0.4	-0.4	-0.7	0.8	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.8	0.3	0.9	0.8	0.6	0.4	0.4	0.5	0.2	-0.1	0.6	0.5	0.7	0.3	0.6	0.5	0.4	-0.6	0.5
Pulse wave Arterial Stiffness index	0.2	0.2	0.8	-0.3	0.9	0.1	-0.3	-0.5	-0.3	0.4	-0.1	0.7	-0.4	-0.4	-0.6	-0.2	-0.3	-0.6	-0.6	-0.1	-0.2
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.9	-0.2	-0.7	-0.5	-0.4	0.0	-0.3	0.5	-0.3	0.2	-0.3	-0.4	0.5	-0.2	-0.4	-0.5	-0.4	1.0	-0.2
Loud music exposure frequency	0.2	0.2	1.3	0.1	-0.7	0.2	0.3	0.4	0.1	-1.1	-0.4	0.3	0.4	0.1	-0.6	0.4	0.2	0.3	0.2	0.0	0.2
Number of children fathered	0.2	0.2	1.9	0.2	-0.6	0.2	0.2	-0.1	0.4	0.9	0.8	0.0	0.2	0.3	1.4	0.2	0.2	0.2	0.4	0.1	0.3
Health satisfaction	0.2	0.2	1.2	-0.2	-0.5	0.0	-0.0	-0.2	-0.1	1.1	-0.9	-1.0	0.0	-0.1	0.2	-0.3	-0.1	-0.1	-0.2	0.3	-0.3
Emphysema/chronic bronchitis	0.2	0.2	0.9	-0.3	-0.1	-0.0	-0.1	-0.2	-0.2	0.8	-0.8	-1.0	-0.2	-0.1	-0.5	-0.4	-0.1	-0.2	-0.3	-0.3	-0.4
Medication: Allopurinol	0.2	0.2	1.1	0.1	1.0	0.8	0.2	-0.5	0.3	0.7	0.3	-0.2	0.1	0.3	-0.3	0.1	0.3	0.4	0.5	-1.1	0.2
Whole body fat mass	0.2	0.7	2.6	-0.8	-1.6	0.3	-0.8	-0.9	-0.8	1.2	-0.1	-0.4	-1.0	-0.8	-0.4	-0.9	-0.8	-0.7	-0.8	-0.2	-0.7
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.5	-0.2	-1.2	-0.7	-0.1	-0.4	-0.1	-0.4	-0.7	-0.0	0.0	-0.1	-0.0	-0.1	-0.2	-0.2	-0.1	1.1	-0.0
Mineral and other dietary supplements	0.2	0.3	1.5	-0.3	0.1	-0.8	-0.5	-0.5	-0.5	1.2	-0.3	-0.0	-0.5	-0.4	-0.1	-0.6	-0.4	-0.3	-0.2	0.9	-0.4
Osteoporosis (self-reported)	0.2	0.2	2.2	0.4	-0.1	0.5	0.4	0.3	0.4	-0.1	1.5	-0.0	0.3	0.4	0.6	0.4	0.4	0.4	0.2	-0.4	0.2
Wears glasses or contact lenses	0.2	0.2	0.9	-0.4	-0.2	-0.3	-0.5	-0.3	-0.4	-1.0	0.1	-0.1	-0.6	-0.5	-0.3	-0.2	-0.5	-0.4	-0.5	0.5	-0.5
Medication: Bendroflumethiazide	0.2	0.3	0.8	-0.5	-0.3	0.1	-0.5	-0.6	-0.5	0.7	0.7	-0.9	-0.7	-0.6	-0.1	-0.6	-0.6	-0.7	-0.6	0.3	-0.6
Number of operations (self-reported)	0.2	0.4	1.3	-0.6	-1.1	-0.5	-0.7	-0.6	-0.5	-0.7	-0.2	-0.4	-0.7	-0.7	-0.3	-0.4	-0.6	-0.6	-0.6	0.2	-0.7
Unable to work because of sickness or disability	0.2	0.3	0.9	0.4	-0.9	-0.7	0.4	0.4	0.4	-0.8	-0.3	0.4	0.3	0.5	0.2	0.5	0.5	0.6	0.5	0.8	0.5
Bipolar Disorder (2018)	0.1	0.2	0.8	-0.4	-0.9	0.1	-0.4	-0.6	-0.3	0.8	0.1	-0.5	-0.5	-0.4	0.1	-0.5	-0.5	-0.5	-0.5	0.2	-0.5
Neuroticism (Nagel 2018)	0.1	0.3	0.7	-0.5	0.8	-0.1	-0.6	-0.0	-0.4	-0.3	-0.8	0.6	-0.7	-0.7	-0.8	-0.2	-0.6	-0.5	-0.6	0.1	-0.2
Crohns Disease (2017)	0.1	0.2	0.7	0.1	0.7	0.4	0.1	-0.3	0.1	-0.1	-0.7	-0.9	-0.1	0.0	-0.3	-0.0	0.2	0.1	-0.3	-0.7	-0.3
Crohns Disease (2012)	0.1	0.2	1.1	0.0	0.4	-0.4	-0.2	-0.7	-0.1	0.8	-0.5	-1.0	-0.4	-0.1	-0.1	-0.3	-0.0	-0.2	-0.5	0.3	-0.5
HDL Cholesterol	0.1	0.2	2.0	-0.1	0.4	0.4	-0.1	0.1	-0.1	-1.4	-0.2	0.6	-0.3	-0.1	0.0	0.1	-0.0	0.1	-0.2	-0.7	-0.0
Hair Pigment	0.1	3.5	6.5	-2.1	-2.5	-2.1	-2.0	-1.0	-2.1	-2.2	-0.6	-0.4	-1.9	-2.1	-2.2	-1.5	-2.1	-2.0	-1.9	1.4	-1.8
Average weekly spirits intake	0.1	0.2	1.4	-0.3	-0.2	-0.7	-0.3	-0.0	-0.3	-0.2	-0.0	-0.5	-0.1	-0.3	0.3	-0.3	-0.3	-0.3	-0.2	1.2	-0.3
Multivitamins +/- minerals	0.1	0.1	0.7	-0.2	-0.2	-0.2	-0.1	0.5	-0.1	-0.1	-0.6	0.8	0.1	-0.1	0.3	0.1	-0.1	-0.1	-0.0	0.2	0.1
Supplements: Glucosamine	0.1	0.2	1.3	-0.4	-0.5	-0.5	-0.3	-0.1	-0.3	-0.5	-1.2	-0.1	-0.2	-0.3	-0.5	-0.2	-0.3	-0.2	-0.4	0.4	-0.3
Medication: Levothyroxine sodium	0.1	0.1	0.6	-0.2	0.1	0.0	-0.2	-0.0	-0.3	-0.8	0.0	0.3	-0.2	-0.2	-0.4	-0.1	-0.2	-0.3	-0.4	0.1	-0.2
Mouth/teeth dental problems	0.1	0.2	0.8	-0.5	-0.9	0.1	-0.4	-0.6	-0.3	0.1	-0.1	-0.7	-0.5	-0.3	-0.0	-0.3	-0.3	-0.4	-0.0	-0.6	-0.3
Neuroticism score	0.1	0.2	1.5	-0.2	1.2	0.2	-0.3	0.1	-0.2	0.3	-0.8	0.5	-0.5	-0.3	-0.5	-0.1	-0.3	-0.2	-0.4	-0.3	-0.0
Impedance of arm (right)	0.1	0.6	2.1	-0.7	-0.0	-1.2	-0.5	0.6	-0.7	-1.4	0.7	1.4	-0.2	-0.6	0.1	0.0	-0.7	-0.7	-0.4	1.2	0.2
Falls in the last year	0.1	0.2	2.0	0.1	-0.5	-0.5	0.1	-0.2	0.3	0.4	-1.4	0.2	0.1	0.1	-0.4	0.2	0.1	0.2	0.1	0.5	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	1.4	-0.1	-1.2	-0.3	0.0	0.4	-0.1	-0.2	1.1	-0.2	0.2	-0.1	0.0	-0.0	-0.0	-0.0	0.0	-0.3	-0.1
Impedance of arm (left)	0.1	0.5	1.8	-0.4	0.2	-1.1	-0.3	0.7	-0.4	-1.2	0.7	1.2	-0.1	-0.3	0.3	0.2	-0.5	-0.5	-0.2	1.3	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	1.5	-0.1	-0.6	0.3	-0.0	0.1	-0.0	1.2	0.1	-0.7	0.0	-0.1	-0.6	-0.2	-0.0	-0.1	0.2	-0.8	-0.2
Medication: Ibuprofen	0.1	0.1	0.5	0.1	0.6	0.6	0.3	0.2	0.2	-0.7	0.3	-0.1	0.3	0.2	0.7	0.3	0.3	0.3	0.1	-0.5	0.3
Had major operations	0.1	0.1	0.5	0.1	-0.7	0.1	0.0	-0.0	0.1	-0.3	0.7	0.2	0.1	-0.1	0.2	0.1	-0.0	-0.2	-0.1	0.0	-0.0
Average weekly champagne plus white wine intake	0.1	0.2	1.2	0.0	1.1	0.4	0.1	0.1	0.0	0.9	0.6	-0.2	0.0	0.0	0.3	-0.2	0.0	-0.1	0.0	-0.6	-0.1
Miserableness	0.1	0.2	1.1	-0.4	-0.5	0.5	-0.2	-0.1	-0.3	0.2	-1.0	0.6	-0.2	-0.4	-0.1	-0.2	-0.3	-0.2	-0.4	-0.1	-0.1
Financial situation satisfaction	0.1	0.1	0.5	-0.2	-0.4	-0.3	-0.1	-0.3	-0.2	0.7	-0.2	-0.6	-0.1	-0.1	0.2	-0.3	-0.2	-0.1	0.1	0.3	-0.2
Age started oral contraceptive pill	0.1	0.2	1.7	-0.1	0.2	0.4	0.1	0.3	-0.0	-0.6	1.3	0.3	0.1	-0.1	0.1	0.2	-0.1	-0.1	-0.2	-0.7	0.0
Heart disease (siblings)	0.1	0.1	0.9	-0.0	-0.9	0.3	-0.1	-0.2	-0.1	-0.6	0.5	0.1	-0.3	-0.1	-0.1	0.0	-0.0	-0.0	-0.2	0.0	-0.2
Trunk fat mass	0.0	0.2	0.9	-0.0	-0.9	0.9	-0.0	-0.3	0.0	0.9	0.4	0.4	-0.2	-0.0	0.3	-0.0	0.0	0.1	-0.0	-0.7	0.1
Had menopause	0.0	0.1	0.3	-0.3	-0.2	0.3	-0.1	-0.2	-0.1	0.1	-0.1	0.0	-0.2	-0.1	-0.4	-0.0	-0.1	-0.2	-0.2	-0.6	-0.1
Pulse rate, automated reading	0.0	0.1	0.4	0.2	0.2	-0.6	-0.0	-0.1	0.1	0.1	0.3	-0.3	-0.0	0.0	-0.0	0.1	-0.1	0.1	-0.1	0.6	-0.2

Hub : Genes

MAP3K3

Models

Trait associations