[Hub]/) : Traits : BMI :

chr2:35,883,253-38,571,255

Best TWAS P=9.47e-09 · Best GWAS P=4.26e-09 conditioned to 1.6e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous AC007401.1 0.10 0.02 lasso 4 0.02 5.4e-03 5.2 5.6 2.3e-08 0.02 0.10 0.79 FALSE
2 GTEx Artery Tibial CRIM1 0.10 0.04 lasso 4 0.05 1.4e-04 5.2 -5.2 2.1e-07 -0.03 0.16 0.78 FALSE
3 GTEx Brain Cerebellar Hemisphere CRIM1 0.36 0.21 lasso 5 0.16 5.4e-05 5.7 5.7 9.9e-09 -0.01 0.04 0.89 FALSE
4 GTEx Brain Cerebellar Hemisphere FEZ2 0.41 0.30 lasso 6 0.28 8.6e-08 5.4 5.5 4.7e-08 -0.03 0.05 0.94 FALSE
5 GTEx Brain Cerebellar Hemisphere AC007401.1 0.40 0.26 lasso 4 0.22 2.3e-06 5.7 5.6 2.2e-08 -0.02 0.04 0.95 FALSE
6 GTEx Brain Cerebellar Hemisphere RP11-490M8.1 0.37 0.18 lasso 4 0.15 1.2e-04 5.3 5.4 7.4e-08 -0.02 0.06 0.78 FALSE
7 GTEx Brain Cerebellum FEZ2 0.44 0.26 lasso 6 0.23 2.6e-07 5.5 5.7 9.5e-09 -0.03 0.03 0.96 TRUE
8 GTEx Brain Cerebellum AC007401.1 0.27 0.21 enet 5 0.20 1.5e-06 5.7 5.6 1.7e-08 -0.02 0.03 0.96 FALSE
9 GTEx Spleen FEZ2 0.42 0.16 enet 25 0.17 3.9e-05 4.7 5.7 1.4e-08 -0.01 0.09 0.74 FALSE
10 GTEx Whole Blood FEZ2 0.11 0.09 enet 25 0.10 8.4e-10 5.4 5.3 1.1e-07 -0.02 0.08 0.92 FALSE
11 GTEx Whole Blood AC006369.2 0.07 0.04 lasso 6 0.04 7.7e-05 -3.9 5.4 8.4e-08 0.07 0.01 0.19 TRUE
12 GTEx Whole Blood AC007401.1 0.06 0.06 lasso 5 0.05 4.6e-05 5.4 5.6 1.7e-08 -0.01 0.06 0.92 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma FEZ2 0.01 0.01 blup 85 0.01 1.0e-03 5.2 -5.2 2.3e-07 0.00 0.04 0.88 FALSE
14 The Cancer Genome Atlas Colon Adenocarcinoma FEZ2 0.11 0.03 blup 84 0.07 6.1e-05 5.0 -5.2 2.3e-07 0.03 0.03 0.95 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma FEZ2 0.06 0.05 blup 87 0.08 1.4e-08 5.3 -5.7 1.5e-08 0.01 0.03 0.97 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma FEZ2 0.07 0.06 blup 87 0.06 2.4e-06 5.3 -5.6 2.7e-08 0.02 0.03 0.97 FALSE