Best TWAS P=4.36e-11 · Best GWAS P=1.34e-10 conditioned to 0.327
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | PPFIA3 | 0.25 | 0.23 | lasso | 4 | 0.21 | 3.9e-06 | 6.1 | -6.6 | 4.4e-11 | -0.91 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | SNRNP70 | 0.05 | 0.02 | lasso | 3 | 0.02 | 2.9e-02 | 5.5 | -6.0 | 1.6e-09 | -0.69 | 0.02 | 0.64 | FALSE |