Best TWAS P=1.51e-17 · Best GWAS P=2.98e-43 conditioned to 7.62e-30
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NAPA | 0.06 | 0.00 | bslmm | 381 | 0.01 | 7.2e-03 | 1.74 | -6.0 | 2.2e-09 | 0.30 | 0.06 | 0.08 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | SAE1 | 0.21 | 0.09 | lasso | 3 | 0.07 | 2.0e-03 | -5.93 | -8.5 | 1.5e-17 | 0.77 | 0.06 | 0.67 | TRUE |
| 3 | METSIM | Adipose | SAE1 | 0.12 | 0.04 | lasso | 5 | 0.07 | 1.7e-10 | -6.57 | -7.4 | 1.4e-13 | 0.61 | 0.61 | 0.39 | FALSE |
| 4 | YFS | Blood | SAE1 | 0.07 | 0.02 | enet | 18 | 0.05 | 3.6e-16 | -6.99 | -6.8 | 9.2e-12 | 0.56 | 0.99 | 0.01 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TMEM160 | 0.04 | 0.00 | blup | 26 | 0.01 | 2.3e-03 | 0.61 | -5.3 | 8.6e-08 | 0.46 | 0.00 | 0.05 | FALSE |